Clinical trials: Mental Illness
Sleep Deprivation
Combined Effects of Acute Sleep Restriction and Moderate Acceleration (+Gz) on Physiological and Behavioral Responses to High Mental Workload
Fighter pilots have to perform tasks requiring high mental workload during moderate-intensity acceleration phases (2 to 3G) that can last several minutes.
- Trial name
- CogPhyAero (NCT06017882)
- Testing
- Partial sleep deprivation
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Delirium
Dexmedetomidine Versus Propofol for Prolonged Sedation in Critically Ill Trauma and Surgical Patients
The purpose of this study is to assess the efficacy of dexmedetomidine versus propofol for prolonged sedation in trauma and surgical patients.
- Trial name
- NCT02548923
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Tennessee Graduate School of Medicine
Autistic Disorder
Evaluation of the Efficiency of Treatment by BUMETANIDE on Autistic Children With a Known Ethiology
During a previous therapeutic trial, investigators showed that the bumetanide improved significantly autism. This trial showed that a therapeutic response was obtained in 75% of cases.
- Trial name
- BUMAUTEP (NCT02947880)
- Testing
- Bumetanide
- Where
- France
- Sponsor
- University Hospital, Limoges
Substance Use, Sexual Risk Behaviors
Targeting HIV Risk Behaviors in Juvenile Drug Court-Involved Youth
This study is designed to gain knowledge about effective interventions for reducing HIV risk in a high risk population. A new Risk Reduction Therapy for Adolescents (RRTA) will be compared to usual services received by youth in…
- Trial name
- NCT01511380
- Testing
- Risk Reduction Therapy for Adolescents, Usual services
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Medical University of South Carolina
Autism Spectrum Disorder, Gastrointestinal Diseases
Fecal Microbiota Transplantation for Patients With Autism Spectrum Disorder.
This study aims to evaluate the efficacy of fecal microbiota transplantation on the gastrointestinal symptoms, autistic symptoms and emotional behavior symptoms of patients with autism spectrum disorder, and investigate the…
- Conditions
- Autism Spectrum Disorder, Gastrointestinal Diseases, Healthy
- Trial name
- NCT06290258
- Testing
- Fecal microbiota transplantation
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Emergence Delirium, Perioperative Neurocognitive Disorder
Quantitative Neurofeedback Techniques for Treating Perioperative Cognitive Disorders in Elderly Patients
The goal of this clinical trial is to learn if quantitative measurement of brain and neurofeedback intervention techniques works to prevent perioperative neurocognitive deficits in elderly oncology patients who are to undergo…
- Trial name
- NCT06752148
- Testing
- neurofeedback intervention training game
- Volunteers
- 390 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Major Depressive Disorder, Neoplasms
Pilot Study to Evaluate Individualized Choice of Antidepressants in Patients With Cancer
This is a pilot study to test the hypothesis that the antidepressants mirtazapine and citalopram are effective treatment for major depressive disorder (MDD) in cancer patients.
- Trial name
- NRR (NCT01725048)
- Testing
- Mirtazapine, Citalopram
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Cardiovascular Diseases, Schizophrenia
Effect of Nutritional Counseling on Anthropometry and Biomarkers in Patients Diagnosed With Schizophrenia/Psychosis or Bipolar Affective Disorder
The goal of this clinical trial is to compare the effect of nutritional counseling versus no treatment in patients with schizophenia or bipolar affective disorder.
- Conditions
- Cardiovascular Diseases, Schizophrenia, Psychosis, Bipolar Disorder
- Trial name
- NCT06197048
- Testing
- Nutritional counseling
- Where
- 2 sites in Norway
- Volunteers
- 40 people
- Sponsor
- Vestre Viken Hospital Trust
Eating Disorder, University Students
Social Media and Eating Disorder Fear
The goal of this observational study is to learn about the relationship between social media use and fear of eating disorders in university students.
- Conditions
- Eating Disorder, University Students, Social Media, Eating Behavior
- Trial name
- NCT06639048
- Testing
- Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 799 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Cannabis, Psychotic Disorders
Cannabinoids, Learning, and Memory
The overarching goal of this study is to characterize the effects of cannabinoids on working and episodic memory.
- Trial name
- THC-Memory (NCT02407808)
- Testing
- THC
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yale University
Social Isolation or Loneliness, Anxiety
Health Surveillance at Constructor University Bremen (CUB)
The aim of Health Surveillance is to analyze and describe the state of health of students at Constructor University, key influencing factors and individual resources by using mixed-method design.
- Conditions
- Social Isolation or Loneliness, Anxiety, Anxiety Depression (Mild or Not Persistent), Health Behavior
- Trial name
- CUB-HS2025 (NCT06899308)
- Testing
- questionnaire
- Where
- 2 sites in Germany
- Volunteers
- 373 people, healthy volunteers welcome
- Sponsor
- Jacobs University Bremen gGmbH
Developmental, Behavioral and Mental Health, Adhd
Using Telehealth to Deliver Mental Health Services in Primary Care Settings for Children in Underserved Areas
In partnership with a multi-site, Los Angeles-area community clinic consortium, North East Valley Health Corporation (NEVHC), the investigators will use telehealth to integrate pediatric developmental, behavioral and mental…
- Conditions
- Developmental, Behavioral and Mental Health, Adhd, Depression, Anxiety
- Trial name
- NCT02396576
- Testing
- Telehealth Intervention
- Where
- 6 sites in United States
- Volunteers
- 359 people
- Sponsor
- University of California, Los Angeles
AD, Early Alzheimer's Disease
A Study to Evaluate the Efficacy and Safety of TTYP01 Tablets in Early Symptomatic Alzheimer's Disease
This is a multicenter, randomized, double-blind, placebo-controlled parallel Phase II core period study to evaluate the efficacy and safety of TTYP01 Tablets in early symptomatic AD (Mild cognitive impairment [MCI] due to AD, or…
- Trial name
- NCT07252440
- Testing
- TTYP01 tables 60mg, TTYP01 tables 90mg, TTYP01 tables 0mg
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Shanghai Auzone Biological Technology Co., Ltd.
Depression
Videoconferencing Acceptance and Commitment Therapy With a Web App Use for Family Caregivers of People With Dementia
The purpose of the pilot study is to assess the effects of an 8-week program on improving mental health in depressed family caregivers of people with dementia.
- Trial name
- NCT05518968
- Testing
- Acceptance and commitment therapy
- Where
- United States
- Sponsor
- University of Alabama at Birmingham
Chronic Insomnia
Interest of Auriculotherapy in the Management of Chronic Insomnia
The aim of the study is to show that auriculotherapy is effective in the treatment of chronic insomnia.
- Trial name
- AURICULO-DODO (NCT04471168)
- Testing
- Cryo-Auriculotherapy
- Where
- 4 sites in France
- Volunteers
- 65 people
- Sponsor
- Hopital Foch
Panic Disorder, Agoraphobia
Providing Tools for Effective Care and Treatment of Anxiety Disorders
PROTECT-AD is a cognitive behavioral treatment study involving highly qualified psychotherapeutic centers at seven German universities.
- Conditions
- Panic Disorder, Agoraphobia, Specific Phobias, Social Anxiety Disorder
- Trial name
- PROTECT-AD (NCT02605668)
- Testing
- Intensified psychological intervention, Standard intervention
- Where
- Germany
- Volunteers
- 726 people
- Sponsor
- Technische Universität Dresden
Type 2 Diabetes, Mild Cognitive Impairment
Transcutaneous Auricular Vagus Nerve Stimulation in Type 2 Diabetes With Mild Cognitive Impairment
This study is a 24-week, single-center, randomized, double-blind, sham-controlled, parallel-group clinical trial. A total of 38 patients with type 2 diabetes and mild cognitive impairment were enrolled and randomly assigned in a…
- Trial name
- NCT07642518
- Testing
- active transcutaneous auricular vagus nerve stimulation
- Volunteers
- 38 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Down Syndrome, Cognitive Dysfunction
Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 6 To 10
The purpose of this study is to determine the efficacy and safety of donepezil hydrochloride (Aricept) in the treatment of cognitive dysfunction shown by children with Down syndrome, aged 6 to 10 years.
- Trial name
- NCT00754013
- Testing
- Aricept (Donepezil hydrochloride)
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Eisai Inc.
Pelvic Floor Dysfunction, Perineal Laceration
Perineal Protection Device for Reducing Perineal Trauma During Vaginal Delivery in First-time Mothers: a Multicenter Randomized Controlled Trial
The goal of this clinical trial is to determine whether using a soft perineal protection device (BabySlide®) in addition to standard manual perineal support during vaginal delivery can reduce the risk of perineal trauma in…
- Conditions
- Pelvic Floor Dysfunction, Perineal Laceration, Wound Dehiscence, Anal Incontinence
- Trial name
- PeriPROTECT (NCT07862660)
- Testing
- Perineal protection device, BabySlide, Standard manual perineal support
- Where
- Sweden
- Volunteers
- 4,226 people
- Sponsor
- Region Skane
Coronary Heart Disease (CHD), Anxiety Disorders
Closed-Loop Neurofeedback Targeting the Right Dorsolateral Prefrontal Cortex for Cardiac Autonomic Modulation in Coronary Artery Disease With Anxiety
The goal of this clinical trial is to test whether real-time fNIRS-BCI neurofeedback targeting the right dorsolateral prefrontal cortex (right DLPFC), using active volitional control during a slow-wave auditory acoustic paradigm…
- Trial name
- HEART-SET-1 (NCT07238920)
- Testing
- Real-time fNIRS-ECG neurofeedback
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Shenyang Medical College
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