Clinical trials: Mental Illness
Substance Withdrawal Syndrome
Does Abstinence From E-cigarettes Produce Withdrawal Symptoms?
The purpose of this study is to see whether adults who use e-cigarettes every day experience symptoms of nicotine withdrawal when they stop using e-cigarettes for 6 days.
- Trial name
- NCT02825459
- Testing
- Abstinence from e-cigarettes
- Where
- 2 sites in United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Pain and Anxiety
The Effect of Virtual Reality on Pain and Anxiety During Colposcopic Biopsy: A Randomized Controlled Trial
The study was planned as a prospective, two-arm (1:1) randomized controlled experimental study to determine the effect of virtual reality applied during colposcopic biopsy on pain and anxiety.
- Trial name
- NCT06811259
- Testing
- Virtual reality (in experimental group), Standart care
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Mersin University
Stress Disorders, Post-Traumatic
Suicide and Trauma Reduction Initiative Among VEterans
The present study is a pragmatic clinical trial that will examine the effectiveness of Cognitive Processing Therapy (CPT) in reducing PTSD symptom severity, depression symptoms, and suicidal thoughts among military personnel and…
- Trial name
- STRIVE (NCT03933059)
- Testing
- Psychotherapy
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Utah
Alcohol Use Disorder
Evaluating the Effectiveness of Implementation Intentions to Strengthen Approach-avoidance Training
Approach Bias Modifcation corresponds to computerized interventions designed to change a cognitive bias (i.e., the approach bias) that may contribute to the maintenance of Alcohol Use Disorder.
- Trial name
- IMBA (NCT06211959)
- Testing
- Approach Bias Modification with Implementation Intentions
- Where
- France
- Volunteers
- 112 people
- Sponsor
- Clinique de la Mitterie
Posttraumatic Stress Disorder, Chronic Pain
Enhancing Cognitive Processing Therapy for Posttraumatic Stress Disorder Via Stellate Ganglion Block Treatment: A Pilot Trial
Cognitive Processing Therapy (CPT) is an effective first-line, evidence-based treatment for posttraumatic stress disorder (PTSD).
- Trial name
- SGB (NCT05534126)
- Testing
- Stellate Ganglion Block Treatment
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Behavioural Problems
Effectiveness of Multisystemic Therapy for Adolescents From Families With Intellectual Disabilities
The goal of this observational study is to determine the effectiveness of a specialisation of multisystemic therapy (MST) for adolescents with severe behavioural problems from families with an intellectual disability (ID…
- Trial name
- NCT06032455
- Testing
- Multisystemic therapy, Multisystemic therapy - intellectual disabilities
- Where
- 4 sites in Netherlands
- Volunteers
- 470 people
- Sponsor
- De Viersprong
Autism Spectrum Disorder, Early Developmental Impairment
Multicenter Validation Study on Autism Screening Using a Machine-assisted System
The goal of this observational study is to assess the effectiveness of a machine-assisted system for early screening of autism. The main questions it aims to answer are: Does the machine-assisted system including 5 main…
- Conditions
- Autism Spectrum Disorder, Early Developmental Impairment, Language Development Disorders
- Trial name
- NCT07006948
- Testing
- Autism Diagnostic Observation Schedule, the 2nd edition(ADOS-2), Griffiths Developmental Scales, Chinese edition(GDS-C)
- Where
- 10 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Restless Legs Syndrome
Observational Study of Sifrol® in Patients With Primary Restless Legs Syndrome (RLS)
The objectives of this Post Marketing Surveillance (PMS) are: Evaluation of the treatment effect of pramipexole on Restless Legs Syndrome (RLS) severity as measured by International Restless Legs Syndrome Scale (IRLS) and…
- Trial name
- NCT02248155
- Testing
- Pramipexole
- Volunteers
- 2,644 people
- Sponsor
- Boehringer Ingelheim
Sleep, Sleep Disturbance
An Exploratory Investigation of a Supplement to Enhance Sleep Quality and Quantity
This double-blind study will examine the effectiveness of Dream Powder and Dream Powder Extra Strength over a six week period. The main outcomes of interest will be sleep quantity and quality, as well as self-reported changes in…
- Conditions
- Sleep, Sleep Disturbance, Sleep Hygiene
- Trial name
- NCT05521243
- Testing
- Beam Organics Dream Powder, Beam Organics Dream Powder Extra Strength
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Beam
Schizophrenia
A Study Comparing the Safety and Efficacy of Ziprasidone and Risperidone for the Treatment of Chronic Schizophrenia
The purpose of this study is to compare the safety of ziprasidone and risperidone for the treatment of chronic schizophrenia. The primary purpose is to differentiate the effects of ziprasidone and risperidone on extrapyramidal…
- Trial name
- NCT00645515
- Testing
- Ziprasidone, Risperidone
- Where
- 3 sites in Spain
- Volunteers
- 240 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Anxiety, Fear Anxiety
Effect of AI(Artificial Intelligence)-Based Storytelling Video on Anxiety and Fear During Skin Prick Test in Children
This study evaluates the effectiveness of an AI-generated therapeutic storytelling video on pre-procedural anxiety and fear levels in children aged 4 to 10 years undergoing their first Skin Prick Test (SPT).
- Conditions
- Anxiety, Fear Anxiety, Allergic Rhinitis, Asthma (Diagnosis)
- Trial name
- NCT07453615
- Testing
- AI-Generated Storytelling Video, Standard Clinic Care
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Antalya Training and Research Hospital
Narcolepsy Type 1, Narcolepsy Type 2
A Study to Investigate the Effects of Cleminorexton Compared With Placebo in the Treatment of Participants With Central Disorders of Hypersomnolence
Narcolepsy Type 1 (NT1) and Narcolepsy Type 2 (NT2) are rare conditions that make people feel very sleepy during the day (often referred to as excessive daytime sleepiness [EDS]).
- Trial name
- NCT07598708
- Testing
- cleminorexton
- Where
- 26 sites in United States
- Volunteers
- 222 people
- Sponsor
- Centessa Pharmaceuticals (UK) Limited
Post Intensive Care Syndrome, Anxiety
Targeted Group-based Psychotherapy to Address Emotional Stress in at Risk ICU Survivors
This study is a pilot clinical trial to assess the feasibility of implementing a group-psychotherapy intervention to modify emotional stress (e.g., anxiety, depression, post-traumatic stress) following ICU hospitalization
- Conditions
- Post Intensive Care Syndrome, Anxiety, Traumatic Stress, Depression
- Trial name
- NCT05856240
- Testing
- Managing Stress & Emotions Group (MSEG)
- Sponsor
- Beth Israel Deaconess Medical Center
Schizophrenia
Effects of Gamified Rehabilitation on Cognitive and Psychosocial Outcomes in Inpatients With Schizophrenia
Schizophrenia is a severe and chronic mental disorder that profoundly impacts patients' psychological, social, and occupational functions. Cognitive impairment is a core symptom that severely limits daily living abilities.
- Trial name
- NCT07557368
- Testing
- Gamified Digital Rehabilitation
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Shanghai Mental Health Center
Alzheimer Disease
Alzheimer's National Registry for Treatment and Diagnostics(ALZ-NET)
The Alzheimer's Network for Treatment and Diagnostics (ALZ-NET) will collect longitudinal clinical and safety data for enrolled patients being evaluated for or treated with novel FDA-approved Alzheimer's disease (AD) therapies.
- Trial name
- ALZ-NET (NCT06170268)
- Testing
- Routine Care Documentation
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Alzheimer's Disease and Related Disorders Association, Inc
Human ARDS, Coronavirus Infection
Post-intensive Care Follow-up of Patients Hospitalized for an Acute Respiratory Distress Syndrome Caused by COVID-19
For the last years, studies have described the " Post-intensive care Syndrome " (PICS), which consists in alteration of quality of life, cognition, autonomy and psychological disorders within the months after intensive-care.
- Trial name
- RE-CoV-ERY (NCT04619368)
- Testing
- Follow up calls
- Where
- France
- Volunteers
- 52 people
- Sponsor
- University Hospital, Toulouse
Alzheimer Disease
Transcranial Magnetic Stimulation (TMS) Treatment for Alzheimer Patients
Transcranial Magnetic Stimulation (TMS) for treatment of Alzheimer disease.
- Trial name
- NCT01334450
- Testing
- TMS , H2-coil
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Hadassah Medical Organization
Pressure Injury, Wound
Pressure Injury Prediction and Education Model Using a Mobile Application System
Pressure injuries are common in the elderly and patients who reduced physical activities. Its complications significantly impact the health care system and social burden, even causing the death rate to be as high as 68%.
- Trial name
- NCT05357391
- Testing
- The Pressure Injury Prediction and Education model using a mobile application system
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch
Attention Deficit Hyperactivity Disorder
Sequencing Treatments for Mothers With ADHD and Their At - Risk Children
We hypothesize that successfully treating maternal Attention Deficit Hyperactivity Disorder (ADHD) will have a beneficial effect that extends to the child.
- Trial name
- TMF (NCT01816074)
- Testing
- Vyvanse (lisdexamphetamine), Behavior Parent Training
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Seattle Children's Hospital
Obesity and Overweight, Sleep Disorder
Overweight and Obesity in Adolescents - Sleep Behavioral Intervention
Sleep plays a crucial role in energy balance, alongside diet and physical activity. Research has linked poor sleep quality and short sleep duration to obesity and cardiometabolic risk, such as insulin resistance and hypertension.
- Trial name
- SLEEP-OB (NCT07255274)
- Testing
- Sleep Behavioral Intervention, Standard Obesity Treatment
- Where
- 2 sites in Portugal
- Volunteers
- 126 people
- Sponsor
- University of Beira Interior
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