Clinical trials: Mental Illness
Posttraumatic Stress Disorder
Dose-Response Study of MDMA-assisted Psychotherapy in People With PTSD
The goal of this clinical trial is to learn if MDMA in combination with therapy is safe and effective in people with chronic, treatment-resistant PTSD.
- Trial name
- NCT01793610
- Testing
- Comparator Dose (40mg) MDMA HCl, Active Dose 2 (100 mg) MDMA HCl, Active Dose 1 (125 mg) MDMA HCl
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Resilient Pharmaceuticals
Daytime Wetting, Enuresis
Voiding School as a Treatment of Children's Day-time Incontinence or Enuresis
The Voiding School is a simple educational intervention to treat children with daytime incontinence or enuresis.The purpose of this study is to implement the intervention in primary care, child welfare clinics.
- Conditions
- Daytime Wetting, Enuresis, Functional Incontinence
- Trial name
- NCT03478813
- Testing
- Voiding school
- Where
- Finland
- Sponsor
- Helsinki University Central Hospital
Cognitive Impairment
Development and Application of Portable Multisensory Stimulation Device
This is a study to develop the vibroacustic devices, and to compare the effects between vibroacustic device therapy and music therapy in adults with dementia or with neck pain.
- Trial name
- NCT04005313
- Testing
- vibroacoustic device
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Autism Spectrum Disorder, Behavior Problem
The Family Check-Up in Autism Services
Many children and youth with autism spectrum disorder have high levels of emotional and behavioural problems. Parents play a powerful role in supporting their children's well-being.
- Conditions
- Autism Spectrum Disorder, Behavior Problem, Emotional Problem
- Trial name
- NCT05280613
- Testing
- Family Check-Up, Treatment as Usual
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- McMaster University
Psychotic Disorders
Fast Titration Of Quetiapine Versus Currently Approved Titration
The purpose of this study is to evaluate the safety and tolerability of a more rapid dose titration in acute schizophrenic patients compared to the conventional titration.
- Trial name
- NCT00254813
- Testing
- Quetiapine
- Where
- 7 sites in Norway
- Volunteers
- 150 people
- Sponsor
- AstraZeneca
BIPOLAR DISORDER
Involvement of the Sodium Pump and Endogenous Digitalis-like Compounds in Bipolar Disorder
This study deals with the possible molecular mechanisms that underlie the etiology of bipolar disorders (BD). Previous studies have implicated Na+, K+-ATPase and endogenous digitalis-like compounds (DLC) in the depressive state…
- Trial name
- NA\K-MANIA (NCT01322113)
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Hadassah Medical Organization
Major Depression
Depression: The Search for Treatment-Relevant Phenotypes-Pilot Study
We are doing this pilot study to learn more about four aspects of treating depression: 1. The features of a depressed person's mood and anxiety and how these features affect a person's capacity to get better and stay better. 2.
- Trial name
- NCT00222820
- Testing
- escitalopram, Interpersonal Psychotherapy
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Pittsburgh
Cognitive Dysfunction
Cognitive Dysfunction in Patients With Cancer Pain
To investigate the occurrence of cognitive dysfunction in cancer patients with pain in China.Analysis of patients with different cancer pain, different analgesic drugs and different treatments are associated with the severity of…
- Trial name
- NCT03641820
- Where
- China
- Volunteers
- 928 people
- Sponsor
- Fujian Cancer Hospital
Sedation, Tolerance
Randomized Study With Midazolam for Sedation in Flexible Bronchoscopy
The Flexible Bronchoscopy (FB) is a diagnostic and therapeutic procedure which is not usually tolerated by the patient. This makes the examination more difficult and a repetition of the examination, if necessary, resulting in a…
- Conditions
- Sedation, Tolerance, Anxiety, Satisfaction
- Trial name
- NCT01038882
- Testing
- Midazolam, Physiological serum
- Where
- Spain
- Volunteers
- 238 people
- Sponsor
- Hospital Universitario La Fe
Dementia, Alzheimer Disease
Translating a Dementia Caregiver Intervention Into a Mobile Application
The overall goal of this development project is to combine elements of two efficacious interventions into a mobile health (mHealth) App for informal dementia caregivers.
- Conditions
- Dementia, Alzheimer Disease, Caregiver Burnout
- Trial name
- NCT04330482
- Testing
- CARE-Well App, Internet Links
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Healthy
Lavender Essential Oil-based Product System for Sleep
The goal of this clinical trial is to learn whether lavender essential oil-based product system can affect gene expression, serum protein markers, and sleep quality in healthy volunteers.
- Trial name
- NCT06510335
- Testing
- Lavender essential oil-based product system
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- dōTERRA International
Nicotine Addiction, Smoking Cessation
Computer-Facilitated 5A's for Smoking Cessation in Primary Care
This study tests the use of handheld computer tablets to promote the integration of 5A's (Ask, Advise, Assess, Assist, Arrange) for smoking cessation in academic and community primary care clinics.
- Trial name
- NCT02046408
- Testing
- Computer Tablet
- Where
- 2 sites in United States
- Volunteers
- 961 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Attention Deficit Disorder With Hyperactivity
Effectiveness and Security Testing of a Mobile App
To assess the effectiveness and security of a mobile App (beta version) for self-managing emotion dysregulation in a pragmatic randomized controlled trial with 80 adolescents with attention-deficit/hyperactivity disorder…
- Trial name
- NCT04519008
- Testing
- Mobile app, Treatment as usual
- Volunteers
- 80 people
- Sponsor
- Consorci Sanitari del Maresme
Anorexia Nervosa
PRE-GAiN Bone Health Pilot Study
This study will assess the affects of an estradiol hemihydrate transdermal system on bone health in 24 adolescent females aged 12-19 years old with anorexia nervosa.
- Trial name
- PRE-GAiN (NCT04021017)
- Testing
- Estradiol Hemihydrate Transdermal System
- Where
- Canada
- Sponsor
- University of Saskatchewan
Overactive Bladder (OAB), Botulinum Toxin Injection
Pretibial TENS for Pain and Anxiety During Intravesical OnabotulinumtoxinA Injection
Overactive bladder is a common condition that causes a frequent, urgent need to urinate and can significantly reduce quality of life.
- Conditions
- Overactive Bladder (OAB), Botulinum Toxin Injection, Procedural Pain Relief, Anxiety
- Trial name
- NCT07707791
- Testing
- Active Pretibial TENS
- Volunteers
- 68 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Laryngomalacia, Gastro Esophageal Reflux
Initiation of Acid Suppression Therapy Prospective Outcomes for Laryngomalacia
Laryngomalacia (LM) is the most common cause of stridor in infants. Symptoms of gastroesophageal reflux (GER) are often seen in the setting of LM; therefore, acid suppression therapy (AST) has been empirically used in the…
- Trial name
- NCT04614974
- Testing
- Famotidine, Speech Language Therapy
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Reema Padia
Bowel Dysfunction
Methylnaltrexone in Patients With Opioid-Induced Bowel Dysfunction
This is a double-blind, randomized, parallel group, dose ranging study of subcutaneous methylnaltrexone to be conducted in patients with advanced medical illness and poorly controlled opioid induced constipation.
- Trial name
- NCT01367574
- Testing
- SC MNTX
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Bausch Health Americas, Inc.
Generalized Anxiety Disorder
Effects of rTMS on the Anxiety State of Older Patients With GAD
The purpose of this study is to evaluate the effects of low-frequency repetitive transcranial magnetic stimulation on anxiety state in older patients with generalized anxiety disorder.
- Trial name
- NCT05883774
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Yi Yang
Schizophrenia
Serum Clozapine and Cognition
This study aim to investigate the relationship between serum levels of clozapine and cognitive performance in patients with ICD-10 Schizophrenia and treated with clozapine monotherapy.
- Trial name
- NCT00951418
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- University of Aarhus
Mitochondrial Diseases, Developmental Delay Disorder
Reference Values of Intraepidermal Nerve Fiber Density in Children and Small Fiber Neuropathy in Neurodevelopmental Disorders
Background: Small-Fiber-Neuropathy describes the degeneration of mildly or unmyelinated nerve fibers and causes neuropathic pain and autonomic dysfunction.
- Conditions
- Mitochondrial Diseases, Developmental Delay Disorder, Small Fiber Neuropathy, Cerebral Palsy
- Trial name
- SFN_children (NCT05645874)
- Testing
- Skin biopsy
- Where
- Germany
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
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