Clinical trials: Mental Illness
Schizophrenia
Folate Supplementation in Schizophrenia
This study aims to examine factors potentially contributing to differences in blood folate, homocysteine or B12 levels between schizophrenia patients, to test the hypothesis that low folate is associated with negative symptoms…
- Trial name
- NCT00249288
- Testing
- Folate
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Massachusetts General Hospital
Post-Traumatic Stress Disorder
Guanfacine for the Treatment of Post Traumatic Stress Disorder (PTSD)
This is a double-blind, placebo-controlled, randomized study lasting 8 weeks. Purpose of the study is two-fold: first, to use a pharmacological agent to treat symptoms of PTSD, and second, to explore neurobiological mechanisms of…
- Trial name
- NCT00018603
- Testing
- guanfacine
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Post Traumatic Stress Disorder, Depression
Treatment of Sleep Disturbances in Trauma-affected Refugees
The overall aim of this study is to examine the effects of sleep enhancing treatment in refugees with PTSD.
- Trial name
- PTF5 (NCT02761161)
- Testing
- Mianserin, Imagery Rehearsal Therapy
- Where
- Denmark
- Volunteers
- 241 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Anxiety, Autism Spectrum Disorder
Adaptation and Feasibility of the Community-Based Anxiety Program Tailored for Autism (CAPTA)
Anxiety is very common in autistic youth. Recently, an intervention has been created by the investigators to target these symptoms in autistic youth in a community setting.
- Conditions
- Anxiety, Autism Spectrum Disorder, Separation Anxiety, Generalized Anxiety Disorder
- Trial name
- NCT06046170
- Testing
- Cognitive Behavioral Therapy, Treatment as Usual
- Where
- 3 sites in United States
- Volunteers
- 32 people
- Sponsor
- Baylor College of Medicine
Insomnia Disorder
Investigating Racing Thoughts in Patients With Insomnia Disorder
Cognitive arousal has been identified as playing a key role in the inability to fall asleep or stay asleep. However, although people with insomnia frequently complain about racing thoughts appearing as soon as they get into bed…
- Trial name
- TIP (NCT04752254)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Strasbourg, France
GAINS Expert Guiding Technology to Coach Life Skill Teaching
GAINS Expert Guiding Technology to Coach Life Skill Teaching
Based on proven techniques in operant conditioning, the expert behavior guiding functionality in GAINS to teach life skills will be evaluated.
- Trial name
- NCT07203105
- Testing
- GAINS expert guiding technology to coach life skill teaching
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Guiding Technologies Corporation
Crohn's Disease, Inflammatory Bowel Disease
GI Symptoms and Sleep Disturbances in Patients With Quiescent Crohns Disease
In this study we would like to clarify the effect of long lasting Crohn's Disease on motility of the gastrointestinal system in patient and the effect regarding sleep disturbances.
- Conditions
- Crohn's Disease, Inflammatory Bowel Disease, Sleep Disturbances
- Trial name
- NCT02245594
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Host and Microbiome, Pregnancy Outcomes
Human Genes and Microbiota in Early Life
The long-term goal of the Human Genes and Microbiota in Early Life (HuGME) is to explore the short- and long-term effects of maternal microbiota during pregnancy and the microbiota colonization of their offspring early in life…
- Conditions
- Host and Microbiome, Pregnancy Outcomes, Pregnancy Complications, Neurodevelopmental Disorders
- Trial name
- HuGME (NCT06926166)
- Testing
- No intervention
- Where
- China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Cocaine-Related Disorders
Effectiveness of GABA Agonists in Reducing the Reinforcing Effects of Cocaine
Cocaine abuse continues to represent a significant public-health concern. Cocaine likely creates its addictive effects by increasing levels of dopamine, a chemical found in the brain.
- Trial name
- NCT00218166
- Testing
- GABA Agonists
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Shotblocker, Injection Pain Prevention
The Effect of SHOTBLOCKER
This study was conducted as a randomized controlled experimental cross over study to examine the effect of injection pain, anxiety and comfort level with the use of Shotblocker in geriatric patients undergoing subcutaneous…
- Conditions
- Shotblocker, Injection Pain Prevention, Pain, Anxiety
- Trial name
- SHOTBLOCKER (NCT06956066)
- Testing
- shotblocker
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istanbul Medeniyet University
Hemophilic Arthropathy
Kinesiophobia in the Parents of Hemophilia Patients
Recurrent joint bleedings lead to the development of a debilitating arthropathy in the patients with hemophilia (PwH). This hemophilic arthropathy (HA) is characterized by chronic pain, periarticular atrophy and a limited range…
- Trial name
- NCT06952322
- Testing
- Questionnaire and Physical Exam
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Bursa City Hospital
Alcohol Dependence, Alcohol-Related Disorders
Remote Alcohol Monitoring and Episodic Thinking
Nearly 18% of United States adults meet criteria for alcohol dependence sometime in their lifetime, with only 24% of those individuals ever receiving any treatment for their disorder (Hasin et al., 2007).
- Trial name
- RMET (NCT03340051)
- Testing
- Episodic Future Thinking (EFT), Episodic Recent Thinking (ERT)
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Major Depressive Disorders
Relapse Predicting Model for First Episode Depression
Major depressive depression(MDD) is an severe public mental disorders. The purpose of current study is using big data analysis based on clinical features and immunochemistry to investigate and establish an relapse predict model…
- Trial name
- RPM-FED (NCT02942251)
- Testing
- Clinical features and medication, Psycho-social, immunology
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Post Operative Delirium
The Effect of Preoperative Duloxetine on the Occurance of Postoperative Delirium in Patients Undergoing Cancer Surgery.
This is prospective double-blinded placebo-randomized controlled trial that aims to compare the effect of preoperative administration of oral duloxetine 60 mg on decreasing the incidence of postoperative delirium in cancer…
- Trial name
- NCT05949229
- Testing
- Duloxetine 60 MG
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Amira Hassan Ahmed Ali
Depression, Anxiety
Testing a Digital Health Intervention App for Depression and Anxiety
Although mobile applications ("apps") for mental health are popular and widely available, little is known about how well they actually help people with common mental health symptoms of depression, anxiety, and stress.
- Trial name
- NCT05373329
- Testing
- Sanvello (app)
- Where
- United States
- Volunteers
- 4,607 people
- Sponsor
- University of Nevada, Las Vegas
Sleep Deprivation
Predicting Cognitive Resilience Against Sleep Loss
Resilience is the ability to cope effectively and adapt to a wide range of stressful environmental challenges. Sleep loss has been shown to reduce activity in the brain regions responsible for resilience.
- Trial name
- NCT01651429
- Testing
- Sleep deprivation
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Postpartum Depression
Birth Experience During COVID-19 Confinement
Different studies have demonstrated that the absence of companionship during labor and childbirth may be responsible for a negative birth experience, an increased risk of postnatal depression and/or post traumatic stress…
- Trial name
- CONFINE (NCT04348929)
- Testing
- Self-administered questionnaires
- Where
- France
- Volunteers
- 927 people
- Sponsor
- Central Hospital, Nancy, France
Neurocognitive Disorders, Alzheimer Disease
Non Verbal Communication and Dementia
Cognitive impairements in Alzheimer's and apparented disorders may lead to the decreased engagement in activities, spetially in moderate and advanced stages of evolution.
- Trial name
- GEMAN (NCT04255329)
- Testing
- Montessori reading roundtable, Usual reading
- Where
- France
- Sponsor
- University Hospital, Montpellier
Stroke
Kinesiophobia and Balance in Stroke Patients
This is a cross-sectional clinical study planned to include 138 stroke patients receiving inpatient treatment at the Istanbul Physical Therapy and Rehabilitation Training and Research Hospital.Data on kinesiophobia (Tampa…
- Trial name
- NCT07241429
- Testing
- Survey using a questionnaire.
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Generalized Anxiety Disorder
Cognitive-Behavioral Treatment and Interpretation Modification Training for Adults With Generalized Anxiety Disorder
Generalized Anxiety Disorder (GAD) is a condition characterized by chronic and excessive worry and anxiety. Our group has developed a cognitive-behavioural treatment (CBT) for GAD that has been tested in four previous clinical…
- Trial name
- CBT+IMT-GAD (NCT01681329)
- Testing
- Cognitive-behavioral therapy, Interpretation training
- Where
- Canada
- Volunteers
- 79 people
- Sponsor
- Concordia University, Montreal
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