Clinical trials: Mental Illness
Disaster Preparedness, Anxiety
The Effect of Basic Disaster Awareness Education on Disaster Literacy and AnxietyLevels in Adolescents
This study aimed to determine the effect of basic disaster awareness education on adolescents' disaster literacy and earthquake anxiety levels.
- Trial name
- ADEB-RCT (NCT07667244)
- Testing
- Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Erzincan Binali Yildirim Universitesi
Alzheimer's Disease
Behavioral Expressions in Alzheimer's Disease
Behavioral expressions, such as agitation and aggression, affect up to 90% of persons with dementia and are a major source of patient and caregiver distress, nursing home placement, anti-psychotic medication use, restraints, and…
- Trial name
- NCT02719834
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Florida
Alzheimer Disease, Late Onset, Cognitive Impairment
Effects of Personalized Music Listening in Advanced Alzheimer's
Recent functional imaging studies have facilitated a better understanding of the neuroplasticity mechanisms underlying the strong and multifaceted effects of music on brain development.
- Trial name
- NCT06765434
- Testing
- Music ( Dmitri Shostakovich's Jazz Waltz Suite), Music( Personalized music)
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Okan University
Diabetes Mellitus, Type 1, Eating Disorders
Safe Management of People With Type 1 Diabetes and EAting Disorders studY
There is currently no effective intervention for type 1 diabetes and eating disorders. The main objective of STEADY Stage 2 is to test the feasibility of the newly developed STEADY intervention.
- Trial name
- STEADY-II (NCT05140564)
- Testing
- STEADY intervention
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- King's College London
Laughter Yoga, Intellectual Disability
Laughter Yoga's Impact on Parental Stress, Burnout, and Self-Efficacy
The present study aims to investigate the effects of laughter yoga on stress levels, burnout, and parental self-efficacy among parents of children with intellectual disabilities.
- Conditions
- Laughter Yoga, Intellectual Disability, Parents, Burnout
- Trial name
- NCT07119164
- Testing
- Laughter yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Heroin Dependence, Opioid-Related Disorders
Effects of Pre-Session Supplemental Hydromorphone on Drug Seeking Behavior in Opioid Dependent Individuals
The purpose of this study is to determine whether the opportunity to take free supplemental hydromorphone (HYD) influences drug seeking behavior in heroin dependent individuals.
- Trial name
- NCT00218309
- Testing
- Hydromorphone
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Depression - Major Depressive Disorder, Menopausal Depression
Interest of Adaptated Physical Activity (APA) on the K Recovery Constant, Reflecting the Rate of Muscle Oxygenation Recovery in Menopausal Women Suffering From Depression
APhyDeM is a randomized controlled study investigating the relationship between adapted physical activity and mitochondrial function in postmenopausal women with major depressive disorder.
- Trial name
- APhyDeM (NCT07417709)
- Testing
- APA, CCATTP
- Where
- France
- Volunteers
- 52 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Pain (Visceral, Somatic, or Neuropathic), Anxiety Acute
The Effect of Sound-Based Interventions on Pain and Anxiety in Pediatric Patients
This study is a prospective, three-arm, single-blind, randomized controlled clinical trial designed to evaluate the effectiveness of non-pharmacological sound-based interventions on pain and anxiety in pediatric patients.
- Trial name
- PED-SOUND-PAIN (NCT07727109)
- Testing
- white noise, pink noise
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Tokat Gaziosmanpasa University
Dementia
Decoding Death and Dying in People With Dementia by Digital Thanotyping
How can healthcare professionals recognize that a person with dementia is at the end of life? When people are dying, their physical, mental, and social abilities are gradually declining.
- Trial name
- 5-D (NCT06437132)
- Testing
- No intervention
- Where
- Norway
- Volunteers
- 270 people
- Sponsor
- University of Bergen
Parkinson Disease, Multiple System Atrophy
A Pilot Biomarker Study Assessing Alpha-synuclein Aggregates Across Biofluid Reservoirs in Patients With Synucleinopathies
This will be an observational study looking at clinical and biomarker characteristics in patients with Parkinson's Disease (PD), Multiple System Atrophy (MSA), Rapid Eye Movement Sleep Behavior Disorder (RBD), Normal Pressure…
- Conditions
- Parkinson Disease, Multiple System Atrophy, Rapid Eye Movement Sleep Behavior Disorder, Normal Pressure Hydrocephalus
- Trial name
- NCT04020198
- Testing
- Biomarker assay
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Hospices, Poly Pharmacy
Standardized Patient-Centered Medication Review in Home Hospice
This is a pilot cluster randomized trial that tests the effect of a novel intervention that trains hospice staff to 1. regularly review, simplify, and align patients' prescribed medications with their goals of care as their…
- Conditions
- Hospices, Poly Pharmacy, Deprescriptions, Caregivers
- Trial name
- SPECTORx (NCT03972163)
- Testing
- NIA Medication Management - Active Comparator, STOPPFrail (Screening Tool of Older Persons Prescriptions), "Discontinuing Medication Appropriately" and "Understanding the Art of Communication about Deprescribing"
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Massachusetts, Worcester
Restless Legs Syndrome, Anxiety
Investigation of the Effects of Different Exercise Programs in Patients With Restless Legs Syndrome.
Restless leg syndrome (RLS) is a very common neurological condition characterized by an uncontrollable desire to move the legs. Due to the traumatic effect of RLS on morbidity, the patient is negatively affected in many different…
- Conditions
- Restless Legs Syndrome, Anxiety, Sleep
- Trial name
- NCT04711993
- Testing
- Aerobic exercise, Stretchin exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Gulhane School of Medicine
Huntington Disease
28-Day Study of SAGE-718 on Functioning Capacity in Participants With Huntington's Disease
The primary purpose of this study is to assess the magnitude of the baseline difference between participants with early Huntington's Disease (HD) and healthy participants (HP) with respect to measures of cognitive performance.
- Trial name
- NCT05358821
- Testing
- SAGE-718
- Where
- 14 sites in United States, Canada
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Supernus Pharmaceuticals, Inc.
Alcohol Use Disorders
Internet Based Cognitive Behavior Treatment for Alcohol Use Disorders
The purpose of this study is to determine whether extensive internet based cognitive behavior treatment program with guidance is a more effective method to treat individuals with alcohol use disorders than a briefer cognitive…
- Trial name
- ICBT-AUD (NCT02645721)
- Testing
- Extended self-help program with guidance, Briefer Self-help program, no guidance, WL: Extended self-help program, choice of guidance intensity
- Where
- Sweden
- Volunteers
- 166 people
- Sponsor
- Karolinska Institutet
Chronic Insomnia
REST: Restoring Effective Sleep Tranquility in College Veterans With Service-Related Injuries
The purpose of the project is to improve the sleep quality and sleep duration of post 9/11 veterans seeking college degrees. Preliminary research findings within CSU's New Start for Student Veterans program indicate veterans with…
- Trial name
- NCT02871414
- Testing
- REST - Early Group, REST - Late Group
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Colorado State University
Pregnant Women, Labor Pain
Neuraxial Labor Analgesia and Offspring Neurodevelopment
How perinatal factors affect the long-term development of children has always been an issue of much concern. This study is designed to explore the potential impact of maternal neuraxial labor analgesia exposure on offspring…
- Conditions
- Pregnant Women, Labor Pain, Analgesia, Epidural, Infants
- Trial name
- NCT04964206
- Testing
- Neuraxial labor analgesia, No neuraxial labor analgesia
- Where
- 2 sites in China
- Volunteers
- 4,645 people
- Sponsor
- Dong-Xin Wang
Cocaine-Related Disorders, Substance-Related Disorders
Dextroamphetamine as an Adjunct in Cocaine Treatment - 1
The purpose of this study is to evaluate dextroamphetamine sulfate (sustained release) as an adjunct in cocaine treatment; an evaluation of the ""replacement"" strategy.
- Trial name
- NCT00000304
- Testing
- Dextroamphetamine, D-Amphetamine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Dementia With Lewy Bodies
Study Evaluating Intepirdine (RVT-101) in Subjects With Dementia With Lewy Bodies: The HEADWAY-DLB Study
This study seeks to evaluate the efficacy and safety of intepirdine (RVT-101) in patients with dementia with Lewy bodies.
- Trial name
- NCT02669433
- Testing
- RVT-101 35 mg, RVT-101 70 mg
- Where
- 65 sites in United States, Canada and 5 more
- Volunteers
- 484 people
- Sponsor
- Axovant Sciences Ltd.
Toxoplasmosis
Role of Circulating MicroRNAs in Differentiating Psychological Disorders Among Women With Chronic Toxoplasmosis
Chronic Toxoplasma gondii (T. gondii) infection is a widespread condition that can negatively affect brain function and is considered a risk factor for various psychiatric conditions, including depression and schizophrenia.
- Trial name
- NCT07346833
- Testing
- Circulating miRNA Expression and T. gondii Serology
- Where
- Egypt
- Volunteers
- 55 people
- Sponsor
- Benha University
Positron Emission Tomography, Alzheimer Disease
CSF1R PET Probe [18F]CSF-23 in Alzheimer's Disease Brain Imaging
To explore the diagnostic value of [18F]CSF-23 brain imaging for CSF1R expression in Alzheimer's disease. PET imaging with this PET tracer was used to assess the role and expression of CSF1R in AD and to evaluate the level and…
- Conditions
- Positron Emission Tomography, Alzheimer Disease, Neurodegenerative Diseases
- Trial name
- NCT06148233
- Testing
- [18F]CSF-23
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
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