Clinical trials: Mental Illness
Stress Disorders, Post-Traumatic
Train Your Brain: Neurofeedback Intervention for PTSD
The investigator's aim is to evaluate the efficacy of two types of neurofeedback treatments for PTSD symptoms reduction. Half of the participants will receive the current standard for PTSD neurofeedback care undergoing…
- Trial name
- NCT03858933
- Testing
- eBrainFit Platform
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Southern California
Inpatient Facility Diagnoses, Psychiatric Disorders
Behavioral Activation - From Inpatient to Outpatient Services
The purpose of this study is to compare the effectiveness of Behavioral Activation and Supportive Therapy added to the standard acute psychiatric inpatient care.
- Conditions
- Inpatient Facility Diagnoses, Psychiatric Disorders, Depressive Symptoms
- Trial name
- NCT01786733
- Testing
- Behavioral Activation, Supportive Therapy
- Volunteers
- 64 people
- Sponsor
- Uppsala University
Trauma Exposure, Trauma
Comparative Effectiveness of SPARCS and Unified Protocol for Youth With Chronic Medical Conditions and Trauma-Related Distress
The goal of this clinical trial is to compare the effectiveness of trauma-focused therapies for improving mental health symptoms and daily functioning in youth with chronic medical conditions who have experienced psychological…
- Conditions
- Trauma Exposure, Trauma, Trauma and Stressor Related Disorder, Mental Health Functioning
- Trial name
- NCT07483333
- Testing
- Structured Psychotherapy for Adolescents Responding to Chronic Stress - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Individual
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Anthony Vesco
Obsessive-Compulsive Disorder
ERP Plus Improv Group Therapy for OCD (IMPROVE Study)
The goal of this study is to pilot test a novel group therapy intervention for adults with OCD.
- Trial name
- NCT06265233
- Testing
- Group Improv sessions, Group Exposure and Response Prevention (ERP) Therapy
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Stanford University
Diabetes Mellitus, Type 2
Feasibility Testing an Exercise Program to Improve Cognition for T2DM Patients
This proposed study will advance science by providing evidence on the feasibility of a standardized, rigorously designed and delivered exercise program to improve cognition and plasma brain-derived neurotrophic factor (BDNF)…
- Trial name
- NCT04590833
- Testing
- Supervised walking on a treadmill, Supervised stretching exercise
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Florida State University
Sleep Disorder, Stage IA Breast Cancer
Brief Behavioral Therapy in Improving Sleep Disorders in Patients With Stage I-III Breast Cancer Undergoing Chemotherapy
This randomized phase II trial studies how well brief behavioral therapy works in improving sleep disorders in patients with stage I-III breast cancer undergoing chemotherapy.
- Conditions
- Sleep Disorder, Stage IA Breast Cancer, Stage IB Breast Cancer, Stage II Breast Cancer
- Trial name
- NCT02002533
- Testing
- Brief Behavioral Therapy, Telephone-Based Intervention, Educational Intervention
- Where
- 6 sites in United States
- Volunteers
- 71 people
- Sponsor
- Gary Morrow
Schizophrenia, Bipolar Disorder
Spanish Validation of Tool Questionnaire to Assess Patients´Perception About Antipsychotic Treatment
Non-interventional, prospective study to validate Spanish version of TOOL questionnaire in patients with schizophrenia and bipolar disorder under antipsychotic treatment
- Trial name
- TOOL (NCT00692133)
- Where
- 32 sites in Spain
- Volunteers
- 250 people
- Sponsor
- AstraZeneca
Alzheimer's Disease, Multiple Sclerosis
A Biospecimen and Clinical Data Study on Patients for Drug & Biomarker Discovery
The purpose of this research project is to collect and store blood samples and clinical data. Researchers can then use the stored samples in future studies.
- Conditions
- Alzheimer's Disease, Multiple Sclerosis, Parkinson's Disease, Huntington's Disease
- Trial name
- NCT01592552
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Post Partum Depression
Adaptation and Pilot Testing of Web and Mobile Interface for the VID-KIDS Intervention
COVID-19 has placed unprecedented strains on parents impacted by toxic stress (depression, addiction, intimate partner violence, and poverty) and reluctant to see mental health-service providers in home/clinic due to fears of…
- Trial name
- VID-KIDS (NCT04818047)
- Testing
- VID-KIDS Intervention Program
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
ASD, Autism
Effects of Neuralli® MP on Self-Defined Outcomes in Adults With Autistic Traits
To evaluate the efficacy of Neuralli® MP in improving participant-defined outcomes in adults with autistic traits.
- Conditions
- ASD, Autism, Autistic Disorders Spectrum
- Trial name
- NCT07064538
- Testing
- Neuralli® MP
- Where
- Taiwan
- Volunteers
- 15 people
- Sponsor
- Mackay Memorial Hospital
Anorexia Nervosa, Bulimia
Effectiveness of Group EFT for Transdiagnostic Eating Disorders/Difficulties Within Student Counselling Services.
What is the purpose of the study? Emotion-Focused Therapy (EFT) is a therapeutic approach that helps individuals identify, explore, and transform difficult emotions to improve emotional wellbeing and resolve psychological issues.
- Conditions
- Anorexia Nervosa, Bulimia, Binge Eating Disorder, Eating Disorder Not Otherwise Specified
- Trial name
- NCT06779838
- Testing
- Group Emotion Focused Therapy Intervention, Treatment as Usual (TAU)
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Canterbury Christ Church University
Tobacco Use Disorder
Examining the Effects of Neural Stimulation on Inhibitory Control and Cigarette Smoking
The purpose of this research study is to examine the effects of theta-burst Transcranial Magnetic Stimulation on inhibitory control and smoking among adult cigarette smokers.
- Trial name
- NCT03960138
- Testing
- Intermittent Theta-burst stimulation (iTBS), Continuous Theta-burst stimulation (cTBS)
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Schizophrenia
Neurobiological Effects of Oxytocin in Schizophrenia - Imaging Study
To investigate whether 24IU oxytocin can result in changes in functional brain connectivity in patients with schizophrenia and healthy individuals using functional magnetic resonance imaging (fMRI).
- Trial name
- NCT04158167
- Testing
- oxytocin
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health and Neuro Sciences, India
Sleep Quality, Relaxation
The Usefulness of Automatic Massage Chairs Before Bedtime in Sleep Quality.
Modern technology is transforming the field of massage, enhancing relaxation and wellness through innovative devices. The automatic electric massage chair exemplifies this advancement, merging ergonomic design with advanced…
- Trial name
- RoboSleep (NCT06784700)
- Testing
- Massage, No intervention
- Where
- Greece
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Insomnia, Depression
A Novel Use of a Sleep Intervention to Target the Emotion Regulation Brain Network to Treat Depression and Anxiety
Several lines of evidence suggest that unhealthy sleep patterns contribute to depressive symptoms through disruption of brain networks that regulate emotional functions.
- Trial name
- NCT04424407
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Stanford University
Anxiety
Virtual Reality Cave Experience With Mindfulness for Mental Wellbeing
The aim of this study is to investigate the effectiveness of a mindfulness-based intervention using a virtual reality cave system for promoting mental wellbeing in youths.
- Trial name
- NCT06351436
- Testing
- Mindfulness
- Volunteers
- 20 people
- Sponsor
- The Hong Kong Polytechnic University
Schizophrenia
Long-acting Injectable Risperidone in Patients With Schizophrenia After an Acute Episode
The primary objective of this randomized trial was to investigate whether early initiation of treatment with Risperdal Consta after an acute episode was not inferior to the routine approach (oral treatment for 12 weeks followed…
- Trial name
- NCT00216671
- Testing
- early initiation of treatment with Risperdal Consta, routine initiation of treatment with Risperdal Consta
- Where
- 31 sites in Denmark, Finland and 8 more
- Volunteers
- 220 people
- Sponsor
- Janssen Pharmaceutica N.V., Belgium
Delirium
Fecal Microbiota Transplantation for the Treatment of ICU Delirium
Delirium in the intensive care unit (ICU) is a prevalent and serious neurological complication among critically ill patients, with large multicenter studies reporting an incidence of 30% to 80%, particularly in those requiring…
- Trial name
- FMTID (NCT07348471)
- Testing
- Intestinal microbiota suspension
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Major Depressive Disorder, Repetitive Transcranial Magnetic Stimulation
Individualized dlPFC-NAcc Modulation for Anhedonia in adMDD
This study evaluates a schedule of precise repetitive transcranial magnetic stimulation for depressive adolescent with anhedonia.
- Trial name
- NCT05544071
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Xijing Hospital
Cannabis Use, Alcohol Use, Unspecified
CARS: Cannabis and Alcohol Reduction Study
The study will test a computerized treatment with subjects ages 13-17 years who are seeking treatment for alcohol and/or cannabis use. Follow-up assessments will be conducted at one- and three-months following treatment.
- Conditions
- Cannabis Use, Alcohol Use, Unspecified, Substance Use, Substance Use Disorders
- Trial name
- CARS (NCT05486234)
- Testing
- modified Approach-Avoidance Task (mAAT), which aims to modify automatic approach bias, modified Approach-Avoidance Task (mAAT) that does not aim to modify automatic approach bias.
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Medical University of South Carolina
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