Clinical trials: Mental Illness
Dementia
Palliative and End-of-life Care in Advanced Dementia: Evaluation of a Program of Organization of Care in Long-term Care
Rationale: In Canada, as in most industrialized countries, Alzheimer's disease and other related dementia are increasingly prevalent in older people.
- Trial name
- NCT01441726
- Where
- Canada
- Volunteers
- 175 people
- Sponsor
- Laval University
Delirium, Dementia, Amnestic, Cognitive Disorders, Arthroplasty, Hip Replacement
Cerebral Regional Oxygen Saturation and Markers of Brain Damage During Primary Hip Arthroplasty
Postoperative Cognitive Disorders (POCD) are common in hospitalized people > 60 year old, especially in orthopedic patients. Etiology of POCD is complex, and in some aspects still remains unclear.
- Trial name
- NCT02342236
- Testing
- cemented or cementless type of hip prothesis
- Where
- Poland
- Volunteers
- 18 people
- Sponsor
- Military Institute od Medicine National Research Institute
Type 2 Diabetes, Overweight
The Effect of Semaglutide on Disordered Eating Behaviour in Type 2 Diabetic Patients
The aim of this study is to evaluate the effect of glucagon-like peptide-1 (GLP-1) receptor agonist semaglutide on disordered eating behaviour in patients with overweight and type 2 diabetes.
- Conditions
- Type 2 Diabetes, Overweight, Disordered Eating Behaviors
- Trial name
- NCT06243536
- Testing
- Semaglutide, standard of care
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- University Hospital Sestre Milosrdnice
ADHD, Cannabis Use Disorder
Delayed-Release, Extended-Release Methylphenidate (Jornay PM) for Adolescents and Young Adults With Attention-Deficit/Hyperactivity Disorder and Cannabis Use Disorder
The goal of this clinical trial is to look at how delayed-release, extended-release methylphenidate (Jornay PM), an FDA-approved medication for the treatment of Attention-Deficit Hyperactivity Disorder (ADHD), works to treat ADHD…
- Trial name
- NCT07838311
- Testing
- Delayed-release, extended-release methylphenidate
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Massachusetts General Hospital
Alzheimer's Disease, Parkinson's Disease
Social Cognition and Personality Changes in Alzheimer's & Parkinson's Disease & Frontotemporal Lobar Degeneration
The aim of this study is to compare personality and social cognition changes, including emotion detection and self-awareness, and neuroanatomical correlates in patients, and how that affects the caregiver-patient relationship.
- Conditions
- Alzheimer's Disease, Parkinson's Disease, Frontotemporal Lobar Degeneration
- Trial name
- NCT02964611
- Testing
- Observational Study
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Major Depressive Disorder
Dose-finding Study With Lu AA24530 in Major Depressive Disorder
The primary purpose of this study is to assess the efficacy in treating patients with Major Depressive Disorder of one or more doses of Lu AA24530 relative to placebo
- Trial name
- NCT00599911
- Testing
- Lu AA24530, Duloxetine
- Where
- 72 sites in Australia, Austria and 15 more
- Volunteers
- 652 people
- Sponsor
- H. Lundbeck A/S
Pregnancy - Prenatal Testing
The Effect of Using Nature Sounds and Virtual Reality During the Non-Stress Test
The aim of this study is to examine the effect of using nature sounds and virtual reality during the non-stress test on fetal well-being, maternal anxiety, comfort, and satisfaction.
- Trial name
- NCT07512999
- Testing
- Virtual Reality, Nature sounds, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Amasya University
Bipolar Disorder
A Preliminary Study of Sustained-Release Bupropion for Smoking Cessation in Bipolar Affective Disorder
The purpose of this pilot study is to determine the safety and potential efficacy of sustained-release bupropion (Zyban®) for the treatment of nicotine dependence in patients with bipolar affective illness.
- Trial name
- NCT00593099
- Testing
- Bupropion
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Schizophrenia
The Hi-tACS on Cognitive Function in Patients With Schizophrenia: a Pilot Study
This study is a double-blind, randomized, controlled intervention study aimed at exploring whether high-frequency transcranial alternating current stimulation (Hi-tACS) can improve cognitive impairment in patients with…
- Trial name
- NCT06231732
- Testing
- high-frequency transcranial alternating current stimulation
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Sir Run Run Shaw Hospital
Postoperative Cognitive Dysfunction, POCD
Optimizing Postoperative Cognition the Elderly
This study will recruit surgical patients more than 65 years old. Patients who participate will wear a sticker on their forehead during surgery which monitors their brain waves (electroencephalogram, EEG) and participate in…
- Trial name
- NCT02650687
- Testing
- Processed EEG
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Mental Health Issue, Anxiety Disorder
Unified Protocol: Community Connections
The purpose of this study is to administer the Unified Protocols for Transdiagnostic Treatment of Emotional Disorders in Children (UP-C) and Adolescents (UP-A) to youth and participants' parents and to examine the efficacy and…
- Conditions
- Mental Health Issue, Anxiety Disorder, Depressive Disorder, Parenting
- Trial name
- NCT06038721
- Testing
- The Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders in Children, The Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders in Adolescents
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- University of Miami
Developmental Delay, Disruptive Behavior
Advancing Child Competencies by Extending Supported Services (ACCESS) for Families Program
The Advancing Child Competencies by Extending Supported Services (ACCESS) for Families Program is a study funded by the National Institutes of Health to explore behavior and developmental problems among young children aging out…
- Trial name
- ACCESS (NCT03260816)
- Testing
- Internet-delivered Parent-Child Interaction Therapy (I-PCIT), Referrals as Usual (RAU)
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- Florida International University
Patients of Laparoscopic Cholecystectomy
The Effect of Listening to Surah Al-Inshirah on Pain and Anxiety After Laparoscopic Cholecystectomy Surgery
In the postoperative period, good pain and anxiety management is required to minimize complications and ensure recovery. Patients should be evaluated with a holistic approach, taking into account factors such as physical and…
- Trial name
- NCT06042114
- Testing
- Surah Inshirah
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Seher Tanrıverdi
Alcohol Dependence
Neuromodulation and Mindfulness Patients With AUD
Our primary objective is to integrate tVNS and mindfulness meditation within a structured mindfulness-based relapse prevention (MBRP) program for detoxified alcohol-dependent patients (AD).
- Trial name
- NCT06308484
- Testing
- Transcutaneous vagus nerve stimulation, Closed-loop AM-tACS
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Charite University, Berlin, Germany
Attention Deficit Hyperactivity Disorder
Long-Term, Open Label Atomoxetine Study
To learn about the safety and any side effects of atomoxetine when given to children and adolescents for about 5 years (long-term) and to learn whether atomoxetine can help children and adolescents with…
- Trial name
- NCT00190684
- Testing
- atomoxetine
- Where
- 100 sites in United States, Australia and 12 more
- Volunteers
- 1,553 people
- Sponsor
- Eli Lilly and Company
Obsessive-Compulsive Disorder
Effectiveness of Deep Brain Stimulation for Treating People With Treatment Resistant Obsessive-Compulsive Disorder
This study will evaluate the safety and effectiveness of deep brain stimulation in treating people with severe and otherwise treatment-resistant obsessive-compulsive disorder.
- Trial name
- NCT00640133
- Testing
- Active DBS
- Where
- 9 sites in United States
- Volunteers
- 27 people
- Sponsor
- Butler Hospital
Type 2 Diabetes Mellitus, Mild Cognitive Impairment
Effects of Olfactory Training on the Brain Function in T2DM Patients With Mild Cognitive Impairment
This is a prospective, randomized, open label, parallel, 4-month study to explore and evaluate the therapeutic effects of olfactory training on the cognitive function, olfactory function, and odor-induced brain activation in T2DM…
- Trial name
- NCT06327633
- Testing
- Olfactory Training
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Genetic Underpinning of Substance Abuse, Polymorphism-genetic
Impact of Delta Opioid Receptor Gene (OPRD1) Variations on Treatment Outcome in African Americans
Background: Differences in peoples genes can make them respond to drugs in different ways. Methadone and buprenorphine are two drugs used to treat drug addiction.
- Conditions
- Genetic Underpinning of Substance Abuse, Polymorphism-genetic, Drug Abuse/Dependence, Opiod-Related Disorders
- Trial name
- NCT02225184
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Feeding Disorder, Nutrition Disorder
Use of Prokinetics in Early Enteral Feeding in Preterm Infants
Objective of this study are: 1) To determine if medication help extreme preterm infants to tolerate feeding better by reaching full feeding earlier.2) Out of two medication; which one is better for efficacy 1) Erythromycin 2)…
- Conditions
- Feeding Disorder, Nutrition Disorder, Infant,Premature
- Trial name
- NCT01569633
- Testing
- Metclopramide, Erythromycin
- Where
- United States
- Sponsor
- East Tennessee State University
General Surgery
The GUARDIAN Pilot Trial
The treatments will be: 1) norepinephrine or phenylephrine infusion to maintain intraoperative MAP ≥85 mmHg, delayed resumption of chronic antihypertensive medications, and a target ward MAP ≥80 mmHg (tight pressure management)…
- Trial name
- GUARDIAN (NCT04789733)
- Testing
- Tight pressure management, Routine pressure management
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The Cleveland Clinic
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