Clinical trials: Mental Illness
Depression, Sleep
The Acute Effect of Aerobic Exercise on Sleep in Patients With Depression
The aim of this trial is to investigate the effects of a single bout of aerobic exercise on sleep in patients with depression.
- Conditions
- Depression, Sleep, Sleep Disorder, Sleep Disturbance
- Trial name
- EASED (NCT03673397)
- Testing
- Aerobic exercise, bicycle ergometer
- Where
- Switzerland
- Volunteers
- 92 people
- Sponsor
- Oberwaid AG
Primary Insomnia
A Phase II/III Study of SEP-190 (Eszopiclone) in Patients With Primary Insomnia (Study 190-126)
The purpose of this study is to investigate and evaluate the efficacy of Eszopiclone in Japanese participants with primary insomnia.
- Trial name
- NCT00770510
- Testing
- Eszopiclone 1 mg, Eszopiclone 2 mg, Eszopiclone 3 mg
- Where
- 20 sites in Japan
- Volunteers
- 192 people
- Sponsor
- Eisai Co., Ltd.
Ischemic Stroke, Intracerebral Hemorrhage
Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY
The overall goal of the DISCOVERY study is to better understand what factors contribute to changes in cognitive (i.e., thinking and memory) abilities in patients who experienced a stroke.
- Conditions
- Ischemic Stroke, Intracerebral Hemorrhage, Subarachnoid Hemorrhage, Dementia, Vascular
- Trial name
- DISCOVERY (NCT04916210)
- Where
- 31 sites in United States
- Volunteers
- 8,000 people
- Sponsor
- Massachusetts General Hospital
Schizophrenia, Smoking Cessation
Deep rTMS Modulating Insula Synaptic Density and Smoking Behavior in Schizophrenia
Purpose of the study: Evaluate the effect of deep repetitive transcranial magnetic stimulation (deep rTMS; hereafter abbreviated as "dTMS") on synaptic density measured with positron emission tomography (PET) and the radiotracer…
- Conditions
- Schizophrenia, Smoking Cessation, Tobacco Use
- Trial name
- NCT05724810
- Testing
- Active deep transcranial magnetic stimulation (dTMS)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Stony Brook University
General Anesthesia
The Relationship Between the SPI and the Postop ED
Surgical plethysmography index (SPI) is a device that can noninvasively monitor the balance between the nociception and ant-nociception using pulse photoplethysmographic amplitude (PPGA) and heart rate obtained through an oxygen…
- Trial name
- SPI_ED (NCT03328910)
- Testing
- SPI monitor (GE Healthcare, Helsinki, Finland)
- Where
- South Korea
- Sponsor
- Daegu Catholic University Medical Center
Cognitive Change, Sleep Deprivation
Sleep Deprivation Study
The purpose of this study is to evaluate the measures of brain function, both neurophysiological (event-related potentials (ERPs) and functional (cognitive assessments), in response to sleep deprivation.
- Conditions
- Cognitive Change, Sleep Deprivation, Caffeine
- Trial name
- NCT05560620
- Testing
- Sleep Deprivation, Caffeine, No Caffeine
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- NeuroCatch Inc.
Sleep, Insomnia
Treatment of Insomnia and Glucose Metabolism
Available data suggest that obtaining adequate sleep is associated with a better ability of the body to use carbohydrates as a source of energy and a lower risk of developing diabetes.
- Conditions
- Sleep, Insomnia, Insulin Resistance
- Trial name
- NCT00724282
- Testing
- Eszopiclone
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Mental Disease
Multidimensional Assessment of Mental Health in Adolescence.
Evidence indicates that many mental disorders in adulthood originate during adolescence, with a typical onset between the ages of 14 and 18, especially for anxiety, mood, and behavioral disorders.
- Trial name
- NCT07422324
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Anxiety, Relapse
"The Evaluation of Stimulant Withdrawal"
The purpose of this research study is to determine whether Carvedilol, an FDA approved beta blocker, when administered for an 8-week period to veterans currently undergoing treatment for methamphetamine dependence (1) improves…
- Conditions
- Anxiety, Relapse, Substance Addiction
- Trial name
- MARC (NCT00442923)
- Testing
- Coreg
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Aaron J. Janowsky
Alzheimer's Disease
OmegAD (Omega-3 and Alzheimer's Disease)
Memory loss and difficulties with thinking associated with Alzheimer's disease (AD) may be due to a deficiency in the brain of a fatty acid named DHA.
- Trial name
- NCT00211159
- Testing
- EPAX 1050TG
- Where
- Sweden
- Volunteers
- 204 people
- Sponsor
- Karolinska University Hospital
Schizophrenia
Effect of Sarcosine on Symptomatology, Quality of Life, Oxidative Stress and Glutamatergic Parameters in Schizophrenia
The purpose of study is to determine whether dietary supplement sarcosine is effective in treatment of schizophrenia. The investigators will assess impact of sarcosine on quality of life and sexual functioning.
- Trial name
- PULSAR (NCT01503359)
- Testing
- Sarcosine
- Where
- Poland
- Volunteers
- 70 people
- Sponsor
- Medical University of Lodz
Alzheimer's Disease
Usability Study of Spaced Retrieval Exercise Using Mobile Devices for Alzheimer's Disease Rehabilitation
The focus of this work is to explore the use of modern mobile technology to enable people with Alzheimer's disease to improve their abilities to perform activities of daily living and hence to promote independence and…
- Trial name
- NCT02005380
- Testing
- Text-based task, Graphic-based Task
- Where
- Jordan
- Volunteers
- 20 people
- Sponsor
- German-Jordanian University
Post Traumatic Stress Disorder
People Bereaved by Violent Death : Negative Event Biases and Temporal Perception
A violent death is defined by its brutality, unexpectedness and is secondary to an external cause (suicide, homicide, accident).
- Trial name
- PrEVENT (NCT05874362)
- Testing
- Diagnosis of depressive episode or post traumatic stress disorder, No diagnosis of depressive episode or post traumatic stress disorder
- Where
- France
- Volunteers
- 61 people
- Sponsor
- Hôpital le Vinatier
Neurodegenerative Disease
Cause and Pathogenesis of Neurometabolic Disorders
This study will examine the origin and development of certain neurological diseases involving abnormal metabolism. A significant number of patients with progressive neurological disorders have not been diagnosed despite extensive…
- Trial name
- NCT00016562
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Erectile Dysfunction
Blood Types and Erectile Dysfunction
The researchers aimed to investigate the relationship between ABO blood types and erectile dysfunction.
- Trial name
- NCT02454946
- Volunteers
- 102 people
- Sponsor
- Ordu University
Severe Mental Disorder, Severe Mental Illness
Musical Intervention for the Management of Anxiety and Stress in People With Severe Mental Disorder in a Medium-stay Unit.
The aim of this study is to analyze the influence of music therapy on perceived anxiety and stress, as well as its effect on the recovery process in individuals with Severe Mental Disorder who are admitted to a Regional…
- Trial name
- NCT07470346
- Testing
- Combined music therapy intervention (active and receptive)
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Alejando Vargas Rubio
Gastrointestinal Dysfunction, Malnutrition
Postoperative GI Dysfunction and Nutrition in Malnourished Cancer Surgery Patients
This is a prospective two-center observational cohort study in adult patients undergoing major abdominal and/or pelvic oncologic surgery with pre-existing malnutrition.
- Conditions
- Gastrointestinal Dysfunction, Malnutrition, Delirium - Postoperative, Abdominal Neoplasm
- Trial name
- GIDNUT (NCT07622888)
- Testing
- Serotonin (e.g., serotonin adipinate), Standard Prokinetic Therapy (excluding serotonin)
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- Arma Ltd.
Gynecological Disease
Online Education and Counseling Regarding Gynecological Examination
This research was carried out to determine the effect of online education and counseling on women's attitudes and anxiety levels regarding gynecological examination.
- Trial name
- NCT05687227
- Testing
- Online education and counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
ADHD
Amphetamine Extended Release Tablets and Driving Performance in Subjects With Attention Deficit/Hyperactivity Disorder (ADHD)
The purpose of this study is to assess the effect on driving performance of a single dose of amphetamine extended-release tablets (20 mg/tablet) compared with placebo at 45 minutes and 10 hours post-dose in young adults with ADHD.
- Trial name
- NCT04027361
- Testing
- Amphetamine Extended Release (ER) Tablet 20 mg
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Tris Pharma, Inc.
Other Conditions That May Be A Focus of Clinical Attention
Chronic Sleep Restriction
Sleep is a physiological state considered essential for health and human survival. The prevalence of chronic sleep restriction has increased in modern society, as well as the effects of the same health concerns about various…
- Trial name
- CSR (NCT01493661)
- Testing
- Chronic Sleep Restriction
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
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