Clinical trials: Mental Stress
Stress
CALM Study: Can A Prebiotic Fibre bLend Improve Stress, Mood, and Anxiety?
This clinical trial will investigate whether a powdered prebiotic fibre blend can improve perceived stress levels in healthy adults with mild-severe stress levels.
- Trial name
- CALM (NCT07201909)
- Testing
- Prebiotic fibre blend, Maltodextrin powder
- Where
- United Kingdom
- Volunteers
- 156 people
- Sponsor
- Myota GmbH
Anxiety, Stress
A Clinical Trial to Assess the Impact of an Alcohol Alternative Herbal Tincture on Signs of Stress Anxiety and Sleep Quality.
This is a virtual randomized placebo-controlled double-blind trial lasting eight weeks. The trial will assess the effects of a test product on improving sleep quality, promoting a sense of calm, and reducing feelings of stress…
- Trial name
- NCT06505694
- Testing
- Alcohol Alternative Herbal Tincture (Test Product)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Apothekary
Stress Disorders, Post-Traumatic
Study To Evaluate The Efficacy And Safety Of Balovaptan In Adults With Post-Traumatic Stress Disorder (PTSD)
This study will evaluate the efficacy and safety of 10 mg of oral administration balovaptan once a day (QD) compared with matching placebo in adults with PTSD.
- Trial name
- NCT05401565
- Testing
- Balovaptan
- Where
- 15 sites in United States
- Volunteers
- 29 people
- Sponsor
- Hoffmann-La Roche
Life Stress, Fatigue
Multicentre, Double-blind Study Versus Placebo on Impact and Safety of Extramel® 140 IU on Perceived Stress, Physical and Intellectual Fatigue, Pain Perception if Present, and the Impact on the Quality of Life
Objectives of this Multicentre, double-blind study versus placebo were to evaluate impact and safety of the daily administration of Extramel® 140 IU SOD for 12 weeks on perceived stress, physical and intellectual fatigue, pain…
- Conditions
- Life Stress, Fatigue, Pain, Quality of Life
- Trial name
- Ex Stress II (NCT01767922)
- Testing
- Extramel 10 mg - 140 UI SOD
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Robertet SA
PTSD - Post Traumatic Stress Disorder
MentalGym™ and NeuroBrave™ Guided Wearable-Assisted Physiology Regulation Training for PTSD (PRTP)
This randomized controlled trial (RCT) will evaluate the effectiveness of a digital biofeedback-based intervention ("Mental Gym®") designed to reduce Posttraumatic Stress Disorder (PTSD) symptoms and improve mental health.
- Trial name
- NCT07462312
- Testing
- Mental Gym® Biofeedback System
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- NeuroBrave ltd.
Parenting Practices, Self Efficacy
Talk Parenting Education Program II
The goal of this clinical trial is to learn whether Talk Parenting, a voice-based program delivered through an Amazon Echo Dot (Alexa), can help parents and caregivers of children ages 3-5 years improve challenging bedtime and…
- Conditions
- Parenting Practices, Self Efficacy, Stress, Child Behavior
- Trial name
- TP2 (NCT07462052)
- Testing
- The Talk Parenting Program
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
PTSD, Anxiety
Exploring Medically Perceived Benefits, Use and Interest in Psychedelics and Cannabinoids
The primary objective of this study is to collect insights from first responders and military personnel on their need for, use of, and interest in physical and/or mental health medical marijuana or psychedelic-assisted therapy…
- Conditions
- PTSD, Anxiety, Anxiety Disorders, Depression
- Trial name
- EMPOWER (NCT04965740)
- Testing
- Cannabis
- Where
- Canada
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Empower Research Inc
Breast Cancer
Online Stress Management and Coping Skills Training for Women With Breast Cancer
Stress Management interventions have been shown to decrease cancer-related distress, foster emotional growth and improve immune functioning during treatment for breast cancer.
- Trial name
- NCT01335152
- Testing
- Coping with Breast Cancer web-based workbook
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Talaria, Inc
PTSD
Proof-of-concept Study to Assess the Efficacy and Safety of SRX246 in Adults With PTSD
18-week, crossover, double-blind, randomized, placebo controlled proof-of-concept study to assess the efficacy and safety of SRX246 (160 mg bid) vs placebo in 52 adult veterans and civilians with a primary diagnosis of PTSD.
- Trial name
- NCT02733614
- Testing
- SRX246
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Azevan Pharmaceuticals
Post Traumatic Stress Disorder
Effectiveness of Sana Treatment in Post-Traumatic Stress Disorder (PTSD)
The purpose of this study is to assess the effectiveness of the Sana Device when added to Treatment as Usual in participants with a diagnosis of post-traumatic stress disorder (PTSD)
- Trial name
- NCT05319405
- Testing
- Sana Device
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Sana Health
PTSD
Open Label Multi-Site Study of Safety and Effects of MDMA-assisted Therapy for Treatment of PTSD
The goal of this clinical trial is to learn if MDMA-assisted therapy is safe and effective in people diagnosed with at least severe PTSD.
- Trial name
- NCT03282123
- Testing
- Midomafetamine, Manualized therapy
- Where
- 12 sites in United States
- Volunteers
- 38 people
- Sponsor
- Resilient Pharmaceuticals
Caregivers
Video-Based Coping Skills Training for Caregivers
The purpose of this Phase II SBIR study is a) to complete the adaptation begun in Phase I of the ten skill modules of the Williams LifeSkills Video (WLV) for use by persons who are caregivers for a relative with Alzheimer's…
- Trial name
- NCT00396825
- Testing
- Video-based coping skills training with telephone coaching
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Williams LifeSkills
PTSD, Mental Illness
Safety and Efficacy of HB-1 for Post-Traumatic Stress Disorder
The purpose of this study is to determine the safety and efficacy of HB-1, versus placebo in male and female adult patients aged 18 to 65 years, inclusive, with Post-Traumatic Stress Disorder (PTSD).
- Trial name
- NCT07499440
- Testing
- HB-1
- Where
- 16 sites in Australia
- Volunteers
- 200 people
- Sponsor
- HB BioTech, LLC
Post Traumatic Stress Disorder
An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD
This study is evaluating the safety and efficacy of TSND-201 in adults with PTSD. Eligible participants will enter a 4-week Treatment Period where they will be randomized 1:1:1 to receive one of two doses of TSND-201 or placebo…
- Trial name
- EMPOWER-2 (NCT07836647)
- Testing
- TSND-201
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Transcend Therapeutics
Intimate Partner Violence, Post Traumatic Stress Disorder
Vedic Counselling for Women Victims of Domestic Abuse
The Vedic Counselling is the whole person approach, system of total life style counselling based on 'Vedic Laws of right living, right actions, right relationship and right awareness'.Vedic Counselling was developed as trauma…
- Trial name
- NCT05261230
- Testing
- Vedic Counselling, Standard Care
- Where
- India
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Active Natural Limited
Stress, Psychological, Healthy
A Study to Assess the Safety and Efficacy of Probiotic to Modulate Psychological Stress
The purpose of this clinical trial is to determine whether Probiotic can modulate the psychological stress experienced by healthy medical, dental and health science students preparing for university/institute of technology…
- Trial name
- NCT04125810
- Testing
- Probiotic
- Where
- 7 sites in Ireland, United Kingdom
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Danisco
Menopause, Menopause Related Conditions
World Digital Detox Program for Enhancing Women's Health & Well-being
The concept of a digital detox, involving a deliberate reduction or elimination of digital device usage, has emerged as a potential strategy to mitigate the adverse effects of technology on mental and physical well-being.
- Conditions
- Menopause, Menopause Related Conditions, Psychological Stress
- Trial name
- NCT06154798
- Testing
- World Digital Detox Women's Health Program
- Where
- India
- Volunteers
- 73 people
- Sponsor
- Innowage Limited
Restless Legs Syndrome, Multiple Sclerosis
Hypnosis and Direct Autonomic Experience Influence on Chronic Symptoms
Study will look at a limited number of participants with various chronic symptoms. Investigating a new and novel form of hypnosis application called "Direct Autonomic Experience (DAX)" which is using combination of visualization…
- Conditions
- Restless Legs Syndrome, Multiple Sclerosis, Trauma, Psychological, Chronic Disease
- Trial name
- HDAX1 (NCT04303143)
- Testing
- Self-Hypnosis, Direct Autonomic Experience Control
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Inner Group Inc.
Post Traumatic Stress Disorder
A Study to Assess the Use of Methylone in the Treatment of PTSD
This study is evaluating the safety, tolerability, and efficacy of methylone in adults with PTSD. The study will be conducted in two parts.
- Trial name
- IMPACT-1 (NCT05741710)
- Testing
- Methylone
- Where
- 16 sites in United States, Ireland and 1 more
- Volunteers
- 79 people
- Sponsor
- Transcend Therapeutics
Substance Use, Stress
Automating Peer Learning to Reduce Alcohol Use and Related Deviant Behavior in Secondary School
Deviant peer affiliation is one of the most important predictors of alcohol use in adolescence. These affiliations arise when socially marginalized youth self-aggregate and reinforce alcohol use and other deviant activity (i.e.…
- Conditions
- Substance Use, Stress, Relation, Interpersonal, Bullying
- Trial name
- PeerLearning (NCT04478240)
- Testing
- PeerLearning.net
- Where
- United States
- Volunteers
- 924 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.