Clinical trials: Mental Stress
Traumatic Brain Injury
Advanced MRI In Acute Military TBI
Traumatic brain injury can cause permanent problems with thinking, memory, control of emotions, organization and planning. Thousands of soldiers, marines, and other military personnel have had injuries to the brain due the wars…
- Trial name
- NCT01313130
- Where
- 2 sites in United States, Germany
- Volunteers
- 400 people
- Sponsor
- Washington University School of Medicine
PTSD, Post-traumatic Stress Disorder
Goal Management Training in Individuals With PTSD
This study will evaluate the effect of a manualized treatment (Goal Management Training, or GMT) on the cognitive impairments associated with PTSD (Post-Traumatic Stress Disorder), as well as any impact on PTSD symptems…
- Conditions
- PTSD, Post-traumatic Stress Disorder, Cognitive Impairment, Cognitive Dysfunction
- Trial name
- NCT04457271
- Testing
- Goal Management Training (GMT)
- Where
- Canada
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Depression - Major Depressive Disorder, Anxiety
Deaf CBT-TS to Reduce Suicide Risk
The goal of this clinical trial is to learn if a short, Zoom-based intervention, Cognitive Behavioral Therapy for Treatment-Seeking for Deaf Individuals (Deaf CBT-TS) can change beliefs about mental health treatment and increase…
- Conditions
- Depression - Major Depressive Disorder, Anxiety, PTSD - Post Traumatic Stress Disorder, Insomnia
- Trial name
- NCT07279363
- Testing
- Deaf CBT-TS
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Rochester
Stroke, Stroke Sequelae
Mindfulness Based Stress Reduction and Post-Stroke Cognition
The investigators don't fully understand how, regardless of the size or location in the brain, minor strokes can result in significant problems with focus, attention, and multi-tasking that prevent individuals from returning to…
- Conditions
- Stroke, Stroke Sequelae, Depression, Cognitive Impairment
- Trial name
- NCT04302493
- Testing
- Mindfulness Based Stress Reduction (MBSR), Stroke Support Group (SSG)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Johns Hopkins University
Adults
Variation in Food Intakes, Physical Activity, and Psychological Stress on Fluctuations in 24-hr Plasma Glucose Levels
This research has the following specific objectives: 1. To elucidate how within-person variation in lifestyle factors affect fluctuations in blood glucose concentrations in individuals at high risk of diabetes.This study will…
- Trial name
- NCT04522063
- Where
- 2 sites in Singapore
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
PTSD
Reconsolidation and EMDR
Blocking of reconsolidation by pharmacological or behavioral means offers the therapeutic possibility of weakening traumatic memories in posttraumatic stress disorder (PTSD).
- Trial name
- NCT02572830
- Testing
- Delayed Bilateral Eye Movements, Undelayed Bilateral Eye Movement
- Where
- Switzerland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Anxiety, Stress and Anxiety
A Psychomotor Group Intervention for Young Adults With Anxiety Symptoms
The goal of this clinical trial is to learn if a psychomotor (a body-oriented therapy) group intervention can be feasibly delivered to a group of young adults (age 18-35) with anxiety symptoms within a higher educational setting.
- Conditions
- Anxiety, Stress and Anxiety, Interoceptive Awareness, Interoception
- Trial name
- NCT07681765
- Testing
- Ten weekly psychomotor therapy group sessions
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- VIA University College
Post Traumatic Stress Disorder
eTMS for Veterans and First Responders With PTSD
A battery of physiological and behavioral data will be collected before and after application of eTMS. Participants will be veterans or first responders diagnosed with PTSD.
- Trial name
- NCT06294106
- Testing
- Electroencephalogram personalized Transcranial Magnetic Stimulation (eTMS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Virginia Polytechnic Institute and State University
Caregiver Burden, Lewy Body Disease
VOCALE LBD+ for Caregivers of Persons With Lewy Body Dementia
The goal of this clinical trial is to evaluate the feasibility, acceptability, and initial efficacy of the VOCALE LBD+ intervention in caregivers of persons living with Lewy Body Dementia.
- Conditions
- Caregiver Burden, Lewy Body Disease, Stress, Skill, Coping
- Trial name
- NCT05622734
- Testing
- VOCALE LBD+
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Washington
Early Onset Dementia, Young Onset Dementia
Anxiety, Stress and Sleep Problems in People With Early Onset Dementia
The aim of this study is to detect and assess needs of people with early onset dementia regarding anxiety, stress and sleep implement a 6 week intervention pilot study in wich weekly (hourly) sessions are implemented in day care…
- Conditions
- Early Onset Dementia, Young Onset Dementia, Stress, Distress, Emotional
- Trial name
- Young-D (NCT05555381)
- Testing
- young-D program
- Where
- 2 sites in Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Alcoholism
Testing Doxazosin to Treat Stress Mechanisms in Alcoholism
Double-blind, placebo controlled, randomized controlled trial (RCT) for Alcohol Use Disorder examining the effects of doxazosin, a norepinephrine alpha1 receptor antagonist, on stress reactivity and clinical outcomes.
- Trial name
- NCT02989493
- Testing
- Doxazosin
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Wisconsin, Madison
Stress, Psychological, Stress, Systemic
Systemic Stress Prevention Via Application SysLife© for Companies
The purpose of this study is to investigate the efficacy of systemic stress prevention via SysLife© application in a prospective, interventive, balanced, monocentric, explanatory pilot randomized controlled trial (RCT), with…
- Conditions
- Stress, Psychological, Stress, Systemic, Application
- Trial name
- NCT05828693
- Testing
- SysLife©, SysLife©, as intervention after closing the RCT-design
- Where
- Germany
- Volunteers
- 49 people
- Sponsor
- University of Witten/Herdecke
Health Behavior
Wearable Emotion Prosthetics for Post Traumatic Stress Disorder
Involuntary stress reactions including hyper-reactivity and dissociation are key diagnostic features of many psychiatric disorders, are difficult to treat, and predict poor outcomes in conventional and neurobehavioral…
- Trial name
- EP-PTSD (NCT03529981)
- Testing
- Tuned Vibroacoustic Stimulation (TVS), no active intervention
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Psychological Distress, Academic Stress
A Single-Arm Trial of a Web-Based Acceptance and Commitment Therapy Mental Health Promotion Intervention for University Students
University students experience high rates of psychological distress and frequently encounter barriers to accessing professional mental health support.
- Trial name
- YOLO UQ (NCT07701330)
- Testing
- YOLO intervention: 4-week web-based intervention
- Where
- Australia
- Volunteers
- 626 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Breast Cancer, Lung Cancer
Pillars4Life Trial
This study aims to explore whether cancer patients can benefit from completing the Pillars4Life online coping program. This randomized control trial will have half its subject completing the program and the other half receiving…
- Conditions
- Breast Cancer, Lung Cancer, Esophageal Cancer, Colon Cancer
- Trial name
- Pillars4Life (NCT02465892)
- Testing
- Pillars4Life
- Where
- United States
- Volunteers
- 284 people
- Sponsor
- Duke University
Posttraumatic Stress Disorder, Prolonged Grief Disorder
Tele-based Psychological Emotional Support for Informal CARegivers of COVID-19 Patients in Intensive Care
The experience of a loved one's stay in a COVID-19 intensive care unit (ICU), either intubated or on respiratory support, forces family caregivers (hereafter 'caregivers') to face core existential fears, such as uncertainty and…
- Conditions
- Posttraumatic Stress Disorder, Prolonged Grief Disorder, COVID
- Trial name
- CO-CarES (NCT04409821)
- Testing
- Tele-delivered psychological intervention
- Where
- 6 sites in Denmark
- Volunteers
- 40 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Posttraumatic Stress Disorder
Psilocybin and Methylenedioxymethamphetamine (MDMA) for Post-traumatic Stress Disorder (PTSD)
The purpose of this study is to assess the safety and effectiveness of co-administered MDMA and psilocybin in military Veterans with a diagnosis of Posttraumatic Stress Disorder (PTSD).
- Trial name
- PAM-VET (NCT06989957)
- Testing
- Psilocybin, MDMA
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Johns Hopkins University
Mental Health, Work Related Stress
Testing the Effectiveness of Mainstream Management Tools to Increase Organizational Commitment and Job Satisfaction and Decrease Turnover Among Peer Providers
The role of peer support specialists (PSS) has burgeoned in the mental health field. Peer support specialists are individuals with a psychiatric condition who are in recovery and who are employed to provide various kinds of…
- Trial name
- NCT04398407
- Testing
- Coaching and Advancement for Peer Providers (CAPP)
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- Boston University Charles River Campus
Anxiety, Depression
A Randomized-Controlled Trial to Investigate the Effect of a Novel Music Therapy Application to Reduce Anxiety and Stress
This virtual, open-label, three-group, randomized-controlled trial will last six weeks. Participants will be allocated into three groups; the Intervention Group, Spotify Group, and Control Group.
- Conditions
- Anxiety, Depression, Stress
- Trial name
- NCT06021821
- Testing
- SoundMind App, Spotify Playlist
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- SoundMind
Stress, Behavior
Brain and Meditation (BAM) Study
This study is a randomized controlled trial to test the impact of an app-based meditation program on perceived stress and behavioral correlates of stress with known neurobiological correlates.
- Trial name
- NCT05215314
- Testing
- mHealth Meditation
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
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