Clinical trials: Mental Stress
Posttraumatic Stress Disorder (PTSD)
Mindfulness-based Stress Reduction for PTSD in Road Traffic Accident Victims: A Randomized Controlled Trial
The goals of the study are to investigate the effects of mindfulness-based stress reduction (MBSR) on PTSD among road traffic accident victims.
- Trial name
- NCT07521020
- Testing
- mindfulness-based stress reduction
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Universiti Sains Malaysia
Mental Health and General Well-being
Effect of a Brief Daily Digital Meditation on Well-Being in US Young Adults (BEGIN II)
This study is testing whether a short, daily, app-based meditation can help young adults feel better in their everyday lives. Adults aged 18-40 years who live in the United States and have not meditated regularly (defined as more…
- Trial name
- BEGIN II (NCT07607782)
- Testing
- Miracle of Mind meditation, Neutral audio learning task
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Anxiety, Stress
Daily Assessment of Mood and Social Media Behaviors Study
The purpose of this research study is to learn more about social media usage and its relation to emotions, biology, and mental health.
- Conditions
- Anxiety, Stress, Depression, Cortisol
- Trial name
- NCT04349423
- Testing
- Social Media Usage Manipulation
- Where
- United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Southern Methodist University
Adolescent Pregnancy
Family Intervention to Improve Maternal and Child Mental Health
This pilot study will assess the acceptability, feasibility and efficacy of a family-based intervention to improve maternal and child mental health by increasing maternal sensitivity and decreasing offspring abuse among…
- Trial name
- MCMH (NCT04700059)
- Testing
- Virtual perinatal home visiting
- Where
- Peru
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Dementia, Alzheimer Disease
Using Technology to Support Care Partners for Persons With Alzheimer's Disease: Tele-STELLA
The purpose of this study is to test a revised psychoeducational intervention to help Care Partners for family members with dementia understand and reduce the distressing behaviors that come with progressive dementia.
- Conditions
- Dementia, Alzheimer Disease, Caregiver Burnout, Family Members
- Trial name
- Tele-STELLA (NCT04627662)
- Testing
- Tele-STELLA
- Where
- United States
- Volunteers
- 375 people
- Sponsor
- Oregon Health and Science University
Generalized Anxiety Disorder, Social Anxiety Disorder
Floatation-REST (Reduced Environmental Stimulation Therapy) for Anxiety and Depression
This early-stage trial aims to examine the feasibility, tolerability, and safety of Floatation-REST (Reduced Environmental Stimulation Therapy) or an active comparison condition in 75 participants with clinical anxiety and…
- Conditions
- Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Agoraphobia
- Trial name
- NCT03899090
- Testing
- Float pool, Float chair
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Chronic Insomnia, Sleep Deprivation
Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia
This clinical trial aims to evaluate the safety and efficacy of PROSOMNIA Sleep Therapy (PSTx) for individuals suffering from chronic insomnia, sleep deprivation, and REM sleep disorders.
- Conditions
- Chronic Insomnia, Sleep Deprivation, REM Behavior Disorder, REM Sleep Behavior Disorder
- Trial name
- PSHW (NCT06644573)
- Testing
- PROSOMNIA Sleep Therapy™ (PSTx), Anesthesia-Induced Sleep Therapy, Diprivan (propofol), Astra-Zeneca
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nyree Penn
Gender Role, Aggression
Creative Drama on Gender Role Stress, Attitudes Toward Violence Against Women, and Aggression
This study aims to examine the effect of Creative Drama on gender role stress, attitudes toward violence against women, and aggression among men who experienced the February 6, 2023 earthquake in Türkiye (centered in…
- Conditions
- Gender Role, Aggression, Violence
- Trial name
- NCT07241156
- Testing
- Creative Drama Program, Film Viewing Sessions
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Critical Illness
Music Listening: A Mechanistic Trial
A randomized within-subject crossover trial to compare the effects of live and recorded music listening on biomarkers of stress and pain among children receiving mechanical ventilation in the pediatric intensive care unit.
- Trial name
- NCT05541029
- Testing
- Live music, Recorded music, Usual care
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- University of Pittsburgh
Anxiety, Post-Traumatic Stress Disorder
Exercise, Mood and Stress Study
Multiple studies indicate that exercise is effective in treating depressed mood and reducing anxiety sensitivity. As depressive symptoms and anxiety sensitivity are elevated in individuals with anxiety and depressive disorders…
- Conditions
- Anxiety, Post-Traumatic Stress Disorder, Depression
- Trial name
- NCT02887027
- Testing
- Exercise4Mood Intervention
- Volunteers
- 4 people
- Sponsor
- Boston University Charles River Campus
Obstructive Sleep Apnea
A Randomized Cross Over Trial of Two Treatments for Sleep Apnea in Veterans With Post-Traumatic Stress Disorder
Sleep disturbances are cardinal features of Veterans with post traumatic stress disorder (PTSD). In particular, obstructive sleep apnea is reported to occur more frequently in patients with PTSD compared to those without PTSD and…
- Trial name
- NCT01569022
- Testing
- CPAP, MAD
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- VA Office of Research and Development
Obesity and Obesity-related Medical Conditions, Menstrual Pain
Quality of Life Variations Among Adolescent Females Following Virtual Reality Games Approach
to compare the effects of virtual reality games, aerobic exercise, and dietary modifications on Quality of Life among adolescent females.
- Conditions
- Obesity and Obesity-related Medical Conditions, Menstrual Pain, Adolescent Obesity, Body Fat Composition
- Trial name
- NCT06604429
- Testing
- Aerobic exercise, Diet Advice, Virtual reality exercise
- Where
- 3 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Mina Atef Georgui Elias
Post Traumatic Stress Disorder
Trauma Treatment in Norwegian Child Advocacy Centers
Norwegian child and advocacy centers´ core activities include both forensic services (e.g., forensic interviews) and follow-up services (e.g., treatment), aiming to coordinate the different services involved in each case to…
- Trial name
- NCT05314829
- Testing
- Trauma-focused cognitive behavioral therapy (TF-CBT)
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Knowledge, Attitudes, Practice, Burnout, Caregiver
Online Training & Certification for Competency in Dementia Friendly Hospital Care
This research study will evaluate the CARES Dementia-Friendly Hospitals online training and certification program for Allied Health Workers (nursing assistants, dietary aides, housekeeping employees, hospital transporters…
- Conditions
- Knowledge, Attitudes, Practice, Burnout, Caregiver, Job Satisfaction
- Trial name
- NCT04182282
- Testing
- CARES Dementia-Friendly Hospitals Online Training and Certification Program
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- HealthCare Interactive, Inc.
Depression, Anxiety
Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors
Conditions treated in intensive care units (ICUs) such as the acute respiratory distress syndrome (ARDS), congestive heart failure, COVID pneumonia, and sepsis are common.
- Conditions
- Depression, Anxiety, Post-traumatic Stress Disorder, Stress
- Trial name
- Blueprint 2 (NCT06538246)
- Testing
- Blueprint, Education program
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Duke University
Psychological Stress
Intermittent Fasting Interventions on Brain Health in Women
Adults experience high psychological stress due to many factors such as school, workplace, or personal life. Adult women are known to experience higher stress levels than men.
- Trial name
- NCT05628727
- Testing
- Time Restricted Feeding, 5:2 Fasting
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- McMaster University
Influenza, Pneumonia, Viral
Long-term Outcome and Lung Capacity in Survivors of ARDS Due to Influenza A (H1N1) v2009 The RESPIFLU Study
Influenza A (H1N1) v2009 infection was responsible throughout the world of viral pneumonia and severe pulmonary edema requiring rescue therapeutics such as extracorporeal oxygenation.
- Conditions
- Influenza, Pneumonia, Viral, Pulmonary Fibrosis, Quality of Life
- Trial name
- RESPIFLU (NCT01271842)
- Where
- France
- Volunteers
- 38 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
PTSD and Trauma-related Symptoms
LIFU Mechanisms for PTSD in Healthcare Workers
The goal of this clinical trial is to evaluate whether low-intensity focused ultrasound (LIFU) of the ventral anterior cingulate cortex (vACC) can normalize dysfunctional brain activation patterns and behaviors in frontline…
- Trial name
- NCT07164105
- Testing
- Low intensity focused ultrasound
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Posttraumatic Stress Disorder
Teaching Loved Ones to Help Veterans Optimize Their PTSD Care and Healing
PTSD occurs in as many as 17% of US military Veterans and is associated with a host of negative, long-term consequences to the individual, their families, and society at large.
- Trial name
- NCT04241094
- Testing
- Loved one assisted treatment
- Where
- 3 sites in United States
- Volunteers
- 28 people
- Sponsor
- VA Office of Research and Development
PTSD (Childbirth-Related), Psychological Wellbeing
Feasibility and Efficacy of GTEP for Birth Trauma
This clinical study aims to evaluate the feasibility and initial efficacy of Group Traumatic Episode Protocol (GTEP) for reducing trauma symptoms (measured by the PCL-5 and City BiTS) for individuals following a traumatic…
- Conditions
- PTSD (Childbirth-Related), Psychological Wellbeing, Bonding
- Trial name
- NCT07246356
- Testing
- Group Traumatic Episode Protocol (GTEP)
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of Birmingham
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