Clinical trials: Mental Stress
PTSD
Effects of Mindfulness-Based Cognitive-Behavioral Conjoint Therapy on PTSD and Relationship Function
The purpose of this study is to first adapt Cognitive Behavioral Conjoint Therapy for PTSD for Operation Enduring Freedom and Operation Iraqi Freedom (OEF-OIF) Veterans diagnosed with PTSD and their intimate partners by (1)…
- Trial name
- NCT01035788
- Testing
- Mindfulness Based Cognitive Behavioral Conjoint Therapy, CBCT for PTSD - Communication Skills
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- VA Office of Research and Development
Postpartum Depression, Postpartum Anxiety
A Postpartum Adaptation Study of the Connecting and Reflecting Experience Parenting Program
Experiencing postpartum mood and/or anxiety disorders (like postpartum depression; PMADs) can make parenting challenging, but group therapy may help both these parents and their babies.
- Conditions
- Postpartum Depression, Postpartum Anxiety, Parenting Stress, Parent Child Relationships
- Trial name
- PMAD-CARE (NCT06042166)
- Testing
- Connecting and Reflecting Experience (CARE) Program
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Montefiore Medical Center
Irritable Bowel Syndrome
The Effect of Laughter Yoga on Symptom Severity, Depression-anxiety-stress, Sleep Quality and Quality of Life in Patients with Irritable Bowel Syndrome
The study will be conducted to evaluate the effect of laughter yoga on symptom severity, depression, anxiety, stress, sleep and quality of life in patients with Irritable Bowel Syndrome (IBS).
- Trial name
- NCT06705153
- Testing
- laughter yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Ataturk University
Posttraumatic Stress Disorder
Building Resilience After Childhood Emergencies (BRACE)
The investigators study seeks to evaluate the feasibility and efficacy of a parent-focused, early intervention to prevent the development of chronic PTSD for children admitted to the emergency department for an acute traumatic…
- Trial name
- BRACE (NCT02898883)
- Testing
- Building Resilience after Childhood Emergencies (BRACE)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Case Western Reserve University
Depression, Anxiety Disorders, Follow-up Study
Nurse Telephone Follow-up for Cardiovascular Patients
This study aims to evaluate the effect of follow-up telephone education provided by a nurse on the levels of anxiety, stress, and depression in patients hospitalized in the cardiac intensive care unit during the two weeks after…
- Conditions
- Depression, Anxiety Disorders, Follow-up Study, Cardiovascular Diseases
- Trial name
- Nurse-TEL-CVD (NCT07120841)
- Testing
- Telephone Education, Standard Care (in control arm)
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Mazandaran University of Medical Sciences
High-normal Blood Pressure, Psychological Stress
A Clinical Trial of the Transcendental Meditation (TM) Program on Blood Pressure, Psychological Distress, and Coping
The purpose of this trial is to show that the Transcendental Meditation program can decrease blood pressure in young adults (college students) and is associated with decreased psychological distress and coping ability.
- Trial name
- AU (NCT00924456)
- Testing
- Transcendental Meditation program
- Where
- United States
- Volunteers
- 296 people, healthy volunteers welcome
- Sponsor
- Maharishi International University
Long Term Adverse Effects, Combat Disorders
Long-term Health Outcomes of AE Casualties
This study involves individuals who are currently participating in the Wounded Warrior Recovery Project and underwent aeromedical evacuation (AE) due to injury during deployment in Iraq or Afghanistan.
- Trial name
- NCT03736356
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Ian Stewart
Schizophrenia, Drug Induced Movement Disorder, Unspecified
Vitamin B6 and B12 in the Treatment of Movement Disorders Induced by Antipsychotics
D2 dopaminergic receptor blockers, used to treat schizophrenia, can lead to the onset of movement disorders. Drug-induced movement disorders encompass several syndromes.
- Conditions
- Schizophrenia, Drug Induced Movement Disorder, Unspecified, Oxidative Stress
- Trial name
- NCT03790345
- Testing
- Pyridoxine, Cobalamin
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara
Stress
Stress Reduction for Busy Professionals
This is a pre-post intervention pilot study to evaluate the impact of a 30-minute, 8-week mind-body/meditation intervention on self-reported quality of life in individuals employed by Allina Health.
- Trial name
- NCT02194478
- Testing
- Meditation
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Allina Health System
Mindfulness, Self-Compassion
Focus Group Study on the Feeling Tone Mindfulness Course
This is an academic research study aiming to explore the acceptability, feasibility, and effectiveness of a four-week feeling tone mindfulness course by gathering qualitative feedback from course participants in a focus group…
- Conditions
- Mindfulness, Self-Compassion, Depression, Anxiety
- Trial name
- NCT06621108
- Testing
- Focus group session
- Where
- Hong Kong
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Major Depressive Disorder (MDD)
Role of Kynurenine Pathway and Its Metabolites in Depressive Disorders, Major Depressive Disorder is Suspected to Have the Greatest Burden by 2030,Kynurenine Pathway is Major Route Through Which the Essential Amino Acid Tryptophan is Metabolised and Activated in Time of Stress and Immune Activation.
This is a case control study including simple random cases of 90 persons, 45 of them have depressive disorders and the other 45 are healthy individuals,age group between 18-60 years old, cases will be recruited from outpatient…
- Trial name
- NCT07771517
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Stress Resilience, Stress
Strengthening Health Literacy in Healthcare Workers Through Mind Body Medicine and Nutrition
This is a randomized controlled trial aiming to develop and evaluate a workplace health program to improve stress resilience and mental well-being among healthcare workers at University Medicine Essen using a participatory…
- Conditions
- Stress Resilience, Stress, Burnout, Burnout Syndrome
- Trial name
- SOULFOOD (NCT07255313)
- Testing
- SOULFOOD Programme
- Where
- Germany
- Volunteers
- 252 people
- Sponsor
- Universität Duisburg-Essen
Bipolar I Disorder
NMDA Receptor Modulation for the Treatment of Bipolar I Disorder
At present, the treatment of Bipolar I disorder (BD-I), especially its depressive episode (bipolar depression), is still limited, because there is no effective treatment for the associated cognitive impairment and perceived…
- Trial name
- NCT05977023
- Testing
- NMDAE
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- China Medical University Hospital
Bipolar Disorder, Caregiver Burden
Psychiatric Nursing Intervention for Caregivers of Patients With Bipolar Disorder
This study aims to evaluate the effectiveness of an innovative psychiatric nursing intervention in reducing caregiver burden and enhancing psychological resilience and positive emotional outcomes among family caregivers of…
- Conditions
- Bipolar Disorder, Caregiver Burden, Psychological Resilience
- Trial name
- BD-Care (NCT07548359)
- Testing
- Psychiatric Nursing Intervention
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Depression
Income Volatility and Mental Health, Pilot Study
Income instability is a defining aspect of the lives of the poor, who also disproportionately suffer from poor mental and physical health.
- Trial name
- NCT06357286
- Testing
- Work opportunities
- Where
- Ghana
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Cornell University
Stress Disorders, Post-Traumatic
Using the Multiphase Optimization Strategy to Adapt Cognitive Processing Therapy
Cognitive Processing Therapy (CPT) consists of discrete therapeutic components that are delivered across 12 sessions, but most Veterans never reach session 12, and those who drop out receive only 4 sessions on average.
- Trial name
- CPT MOST (NCT05220137)
- Testing
- Modified A-B-C: Working with Events, Thoughts, and Feelings, Challenging Questions, Patterns of Problematic Thinking
- Where
- 3 sites in United States
- Volunteers
- 271 people
- Sponsor
- VA Office of Research and Development
Post Traumatic Stress Disorder
Neural Control and Cardiac-Vascular Function in Women With PTSD (VA Psychological Assessment)
The purpose of this research is 1) to investigate the role of the sympathetic nervous system and cardiac-vascular function in women with PTSD; and 2) to determine whether lifestyle modifications (exercise training and healthy…
- Trial name
- NCT03929939
- Testing
- Exercise training and healthy eating (overseen by IEEM research team)
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- North Texas Veterans Healthcare System
Mild Cognitive Impairment, Caregiver Burden
A rTMS and Virtual Reality Based Cognitive Rehabilitation Program for MCI
This clinical trial is being conducted to see if brain stimulation and brain training together improves cognitive functioning and mood in older adults diagnosed with Mild Cognitive Impairment (MCI).
- Conditions
- Mild Cognitive Impairment, Caregiver Burden, Mental Health Issue, ADL
- Trial name
- rTMS+iVCT (NCT06024473)
- Testing
- rTMS, rTMS+iVCT
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Central Arkansas Veterans Healthcare System
Anxiety, Comfort
The Effect of Stress Ball on Anxiety, Comfort and Non Stress Test Parameters of Pregnant Women During Non Stress Testing
Non-stress testing (NST) is used to assess fetal wellbeing and to detect and intervene early in fetuses at risk. NST is an easy to administer, noninvasive, prenatal assessment method used from 32 weeks of gestation to term.
- Trial name
- NCT06741254
- Testing
- Stress Ball
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Gaziantep Islam Science and Technology University
Childhood Traumatic Grief, Post Traumatic Stress
Randomized Controlled Trial of Trauma-focused CBT in Tanzania and Kenya
The primary goal is to study the effectiveness of Trauma-focused Cognitive Behavioral Therapy (TF-CBT) in treating traumatic grief and traumatic stress for orphaned children and young adolescents in two East African sites with…
- Conditions
- Childhood Traumatic Grief, Post Traumatic Stress, Post Traumatic Stress Disorder, Depressive Symptoms
- Trial name
- NCT01822366
- Testing
- Trauma-focused Cognitive Behavioral Therapy
- Where
- 3 sites in United States, Kenya and 1 more
- Volunteers
- 1,280 people
- Sponsor
- Duke University
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