Clinical trials: Mental Stress
Post Traumatic Stress Disorder (PTSD), Depressive Symptoms
The Norwegian Stepped-Care TF-CBT Study
Every day, a significant number of children and young people in Norway experience violence, abuse, or other potentially traumatizing events.
- Conditions
- Post Traumatic Stress Disorder (PTSD), Depressive Symptoms, Parental Stress, Health Related Quality of Life
- Trial name
- NCT04073862
- Testing
- Stepped-Care TF-CBT
- Where
- Norway
- Volunteers
- 82 people
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
Video-conferencing FACT for Young Children With Special Needs
Objective: This RCT evaluates the efficacy of Focused Acceptance and Commitment Therapy (FACT) delivered via videoconferencing for parents of special needs children, targeting reducing parental stress (primary outcome), symptoms…
- Conditions
- Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Specific Learning Disorder, Communication Disorders
- Trial name
- NCT06262646
- Testing
- Focused Acceptance and Commitment Therapy, Control Group
- Where
- Hong Kong
- Volunteers
- 254 people
- Sponsor
- Chinese University of Hong Kong
Alcohol Use Disorder (AUD)
Developing a Music Listening mHealth Intervention for Stress Reduction in Early Recovery
The overarching goal of this study is to develop and examine the feasibility of a music-listening intervention that can be deployed in "real time" to regulate emotions and reduce momentary stress among young adults within the…
- Trial name
- CalmiFy (NCT07052318)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Washington State University
PTSD, Post-traumatic Stress Disorder
Deep Brain Reorienting in Post-traumatic Stress Disorder
This study will evaluate the efficacy of a therapeutic treatment, Deep Brain Reorienting (DBR), for PTSD (Post-traumatic Stress Disorder). Participants will be randomized to either the DBR treatment, or wait-list condition.
- Trial name
- NCT04317820
- Testing
- Deep Brain Reorienting (DBR)
- Where
- Canada
- Volunteers
- 234 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Alcohol Abstinence
Guanfacine to Reduce Relapse Risk in Women With Alcohol Use Disorder (AUD)
Guanfacine may preferentially reduce craving and improve cognitive control in women with Alcohol Use Disorder (AUD), compared to men.
- Trial name
- NCT03137082
- Testing
- Guanfacine XR 3mgs/daily
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Stony Brook University
Stress Disorders, Post-Traumatic
Trial of Paroxetine-CR for the Treatment of Patients With Post Traumatic Stress Disorder Remaining Symptomatic After Initial Exposure Therapy
The purpose of the study is to evaluate the effectiveness and tolerability of controlled-release paroxetine (Paxil-CR) compared to placebo (an inactive substance) for individuals who continue to have symptoms of post traumatic…
- Trial name
- NCT00121888
- Testing
- Prolonged Exposure Therapy, Paroxetine-CR
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Caregiver Stress, Caregiver Stress Syndrome
ACT Group for Family Caregivers of Stroke Survivors
The goal of this study is to evaluate the efficacy of group-based ACT intervention in improving the levels of psychological distress in caregivers of stroke survivors. The main questions it aims to answer are: 1.
- Conditions
- Caregiver Stress, Caregiver Stress Syndrome, Caregiver Burnout, Caregiver Distress
- Trial name
- NCT07528261
- Testing
- Group-based ACT Intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Wright Institute
Obesity, Metabolic Syndrome
Feasibility Trial of Functional Clothing, Moderate Exercise, and Health Information for Stress Reduction and Behavior Change in Okinawa
This study is a pilot randomized trial conducted in Yomitan Village, Okinawa, Japan. The purpose is to evaluate whether three simple, low-cost interventions can help reduce stress and support healthy behavior change in…
- Conditions
- Obesity, Metabolic Syndrome, Stress, Psychological
- Trial name
- Y-RELIVE (NCT07204483)
- Testing
- Educational Leaflet, Functional Shirt (Relive brand), Exercise Manual
- Where
- Japan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Shinyu Kise
PTSD, Alcohol; Use, Problem
Evaluating Signs of Safety: A Deaf-Accessible Therapy Toolkit for AUD and Trauma
The U.S. Deaf community - a group of more than one million Americans who communicate using American Sign Language (ASL) - experiences nearly triple the rate of lifetime problem drinking and twice the rate of trauma exposure…
- Trial name
- NCT06278922
- Testing
- Seeking Safety + Signs of Safety toolkit, Treatment as usual
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of Massachusetts, Worcester
Posttraumatic Stress Disorder
Group vs. Individual Cognitive Processing Therapy for Combat-related PTSD
The purpose of this study is to conduct a randomized controlled trial to compare group and individual CPT-C for the treatment of PTSD in OIF/OEF military personnel.
- Trial name
- NCT02173561
- Testing
- Group Cognitive Processing Therapy-Cognitive Only, Individual Cognitive Processing Therapy-Cognitive Only
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Duke University
Alcohol Dependence
Multimodal Neuroimaging of Stress and Reward Cues to Assess Alcoholism Risk and Relapse
Extending previous findings, and applying a novel multi-method translational approach, this project hypothesizes that there are alcohol-related neuroendocrine and neural changes observable in acute and protracted abstinence, and…
- Trial name
- NCT02616094
- Testing
- Multi-method Neuroendocrine and Neuroimaging Procedure Scan 1, Multi-method Neuroendocrine and Neuroimaging Procedure Scan 2
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Yale University
Traumatic Brain Injury (TBI), Post Traumatic Stress Disorder (PTSD)
Effectiveness of a Driving Intervention on Safe Community Mobility for Returning Combat Veterans
The main objective of this study is to discern if an Occupational Therapy Driving Intervention (OT-DI) improves fitness to drive abilities of Combat Veterans and also investigate if results leads to reduced driving errors on the…
- Trial name
- NCT02765672
- Testing
- Driving Behavior Interview, Clinical Driving Assessment, Propensity for Angry Driving Scale
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- University of Florida
Sleep Apnea Syndromes, Insomnia Disorder
Apnea and Insomnia Relief Study
The purpose of this study is to determine whether a behavioral sleep treatment improves functioning and sleep in Veterans with posttraumatic stress disorder (PTSD).
- Conditions
- Sleep Apnea Syndromes, Insomnia Disorder, Stress Disorders, Post-Traumatic
- Trial name
- AIR (NCT04007796)
- Testing
- Apnea and Insomnia Relief (AIR), Sleep Education (SE)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Post Traumatic Stress Symptoms, PTSD
Nonattachment Training for Post Traumatic Stress Recovery
This pilot study aims to investigate the effectiveness of a novel, co-created intervention based on principles of nonattachment for individuals recovering from Post-Traumatic Stress (PTS). Objectives include: 1.
- Trial name
- NPTS (NCT06683027)
- Testing
- Nonattachment for Post Traumatic Stress
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Derby
Postpartum Mothers
Impact of IBSR on Postpartum Mothers' Mental Health.
The period of pregnancy, childbirth, and the postpartum phase significantly impacts the mental health of women and their families.
- Trial name
- NCT06490094
- Testing
- Inquiry Based Stress Reduction (IBSR)
- Where
- Israel
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Birth, First, Pregnancy Related
The Effect of the Continuous Midwifery Care Model on Birth Outcomes
It is the right of both the mother and her baby to receive the best care and give birth in the best way possible for every pregnant woman.
- Conditions
- Birth, First, Pregnancy Related, Newborn; Fit, Trauma, Psychological
- Trial name
- NCT06020339
- Testing
- The midwife-led continuous care model (MLCC)
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Well-Being, Psychological, Mood
Mushrooms, Mood and Mental Wellbeing in Gen Z Women
The aim of the study is to investigate the effects of 28 days supplementation of Lions mane mushroom and mushroom blend of Lions mane and reishi mushroom, on wellbeing in stressed or anxious women.
- Conditions
- Well-Being, Psychological, Mood, Anxiety, Stress
- Trial name
- NCT06406946
- Testing
- Lion's mane blend, Lion's mane and reishi blend
- Where
- United Kingdom
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Pain, Stress
The Effect of Music on Procedural Distress During Mobilization in Intensive Care Unit Patients: A Randomized Controlled Trial
This intervention study will investigate the effects of music therapy on procedural distress, the overall experience of pain, anxiety, and stress, during the procedure of sitting up in a chair for patients admitted to the…
- Conditions
- Pain, Stress, Anxiety
- Trial name
- MUSICU (NCT06174662)
- Testing
- Music
- Where
- Belgium
- Volunteers
- 128 people
- Sponsor
- Universiteit Antwerpen
Posttraumatic Stress Disorder
Emotional Memory Reactivation in Posttraumatic Stress Disorder
Converging lines of evidence have implicated the amygdala in the pathophysiology of posttraumatic stress disorder. The primary purpose of our study is to assess the effect of propanolol, a beta adrenergic antagonism, on amygdala…
- Trial name
- VIVITRAU (NCT01239173)
- Testing
- AVLOCARDYL
- Where
- France
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Posttraumatic Stress Disorder, PTSD
Adaptive Decision-making And Personalized Treatment for PTSD (ADAPT-PTSD)
By doing this research project, the investigators hope to learn which strategies work best to help veterans who are not benefiting from their first PTSD treatment or not completing between-session homework assignments regularly…
- Trial name
- ADAPT-PTSD (NCT07176273)
- Testing
- Modular Cognitive Processing Therapy, Modular Prolonged Exposure Therapy, Step Down Treatment
- Where
- 4 sites in United States
- Volunteers
- 302 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
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