Clinical trials: Mental Stress
Post-traumatic Stress Disorder
Effectiveness of a Blended Care Parenting Intervention for Parents With PTSD (KopOpOuders-PTSD)
KopOpOuders-PTSD is a new preventive blended care intervention for parents with PTSD. The purpose of this study is to evaluate its effectiveness in improving parenting and preventing child mental health problems.
- Trial name
- NCT05237999
- Testing
- KopOpOuders-PTSD
- Where
- Netherlands
- Volunteers
- 142 people
- Sponsor
- Arkin
Post-traumatic Stress Disorder (PTSD), Trauma
Functional Brain Imaging in PTSD
Patients with post-traumatic stress disorder (PTSD) have abnormalities in the function of the amygdala and medial prefrontal cortex (particularly anterior cingulate), in addition to abnormalities of hippocampal volume.
- Trial name
- NCT02053532
- Testing
- Positron emission tomography/magnetic resonance imaging
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
COVID-19 (SARS-CoV-2 Infection)
Use of a Cysteine-rich Whey Protein Isolate in Post COVID-19 Cognitive Impairment
Abstract Background: Post-COVID-19 cognitive impairment (PCCI), characterized by deficits in attention, memory, and executive functioning, remains a major challenge among patients with long COVID.
- Trial name
- NCT07184398
- Testing
- Intervention with Consolidated Cysteine (Immunocal) 20 g per day, Cognitive rehabilitation workshops
- Where
- Colombia
- Volunteers
- 120 people
- Sponsor
- Universidad Libre seccional Cali
Tobacco Use Disorder
Medicinal Nicotine for Preventing Stress Induced Craving and Withdrawal Symptoms
The purpose of this study is to determine the timeframe (relative to a stress task) that is most effective at attenuating the increase in symptoms of tobacco craving and withdrawal that occur when smokers are presented with…
- Trial name
- NCT01522963
- Testing
- Nicotine lozenge
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- University of Minnesota
Sleep Deprivation, Military Activity
Can Ammonium Inhalants Maintain Performance in Sleep Deprived Soldiers?
This study aims to examine the effectiveness of ammonia inhalants in countering the effects of total sleep deprivation on cognitive and physical performance tests relevant to military personnel.
- Conditions
- Sleep Deprivation, Military Activity, Sleep, Cognitive Change
- Trial name
- NCT05868798
- Testing
- Ammonia Inhalant
- Where
- Czechia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Jan Malecek
Posttraumatic Stress Disorder
Comparing Imaginal Exposure and Imagery Rescripting in Treatment of Posttraumatic Stress Disorder (PTSD)
The outcome of trauma treatment (Posttraumatic Stress Disorder - PTSD) may be influenced by which emotions that are predominant among current symptoms, e.g. fear, anger, guilt, shame.
- Trial name
- NCT00891098
- Testing
- Imaginal exposure, Imagery rescripting
- Where
- Norway
- Volunteers
- 65 people
- Sponsor
- Modum Bad
Post Traumatic Stress Disorder PTSD
Inhaled Cannabis for Treatment of PTSD
The rationale for the use of inhalational cannabis to potentially treat PTSD symptoms is based on the many reports of cannabis attenuating PTSD symptom expression among individuals with PTSD, including veterans.
- Trial name
- NCT07224698
- Testing
- High THC Cannabis
- Volunteers
- 320 people
- Sponsor
- Multidisciplinary Association for Psychedelic Studies
Study Focus is Healthcare Interventions and Health Inequalities
Yoga Nidra for Stress, Sleep Quality, and Academic Resilience in Nursing Students
The purpose of this study is to examine the effects of Yoga Nidra on stress, anxiety, sleep quality, and academic resilience among nursing students during clinical practicum.
- Trial name
- YNSAR (NCT07631117)
- Testing
- Yoga Nidra Intervention Group
- Where
- Taiwan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- LEE CHIN-TING
Occupational Stress and Mental Health in Clinical Nurses, Burnout
On-Demand AI Support Via LINE-Based GPT Assistant to Improve Emotional Resilience and Reduce Burnout Among Clinical Nurses
Clinical nurses are frequently exposed to high emotional demands due to heavy workloads, time pressure, patient suffering, and the interpersonal complexity of clinical care.
- Conditions
- Occupational Stress and Mental Health in Clinical Nurses, Burnout, Compassion Fatigue, Psychological Resilience
- Trial name
- Nurse-AI-CARE (NCT07380685)
- Testing
- Interactive LINE GPT Emotional Support, Static Supportive Messages
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital
PTSD - Post Traumatic Stress Disorder, Stress Disorder, Post Traumatic
Evaluation of the Effect of an Emergency Department Information Video on the Risk of Post-Traumatic Stress Disorder 30 Days After an Emergency Visit.
Post-traumatic stress disorder (PTSD) is a psychological disorder characterized by the re-experiencing of distressing symptoms, avoidance of traumatic memories and physiological hyperarousal in people who have been exposed to a…
- Trial name
- VISU (NCT06755606)
- Volunteers
- 750 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Post Traumatic Stress Disorder
Written Exposure Therapy for Post-traumatic Stress Syndrome
To investigate if written exposure therapy is feasible for patients with post-traumatic stress disorder
- Trial name
- NCT04328935
- Testing
- WET
- Where
- Sweden
- Volunteers
- 12 people
- Sponsor
- Karolinska Institutet
Interpersonal Psychotherapy, Family Caregivers
Application of Group Interpersonal Psychotherapy (IPT-G) to Family Members Caring for Patients With Schizophrenia
The goal of this re-measured quasi-experimental study is to evaluate the effect of Group Interpersonal Psychotherapy (IPT-G) intervention given to caregiver family members of people with schizophrenia on caregiver burden…
- Trial name
- IPT-G (NCT05870384)
- Testing
- Group Interpersonal Psychotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Inflammation, Depression Disorder
Inflammatory Pathways Modulated by Prenatal Mindfulness: A Route to Improve Maternal Child Emotional Well Being and Whole Person Health
The goal of this study is to investigate inflammation as the biological mechanism by which mindfulness based cognitive therapy for perinatal depression (MBCT-PD) administered during pregnancy improves women's emotional well-being…
- Conditions
- Inflammation, Depression Disorder, Mindfulness, Emotional Well-being
- Trial name
- NCT07892326
- Testing
- Mindfulness-based cognitive therapy for perinatal depression, Pregnancy Health Group
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Oregon Health and Science University
Cancer Survivors
Program of Exercise, Diet and Control of Psychological Stress in Cancer Survivors
A program of exercise, diet and psycho-emotional support could improve some outcomes in cancer survivors.
- Trial name
- EDICOS (NCT01108484)
- Testing
- Exercise, Exercise + Diet counseling, Exercise + Diet counseling + psycho-emotional support
- Where
- 2 sites in Spain
- Volunteers
- 140 people
- Sponsor
- Grupo de Investigación en Actividad Física y Salud
Suicide, Trauma, Psychological
Wakȟáŋyeža (Little Holy One)
The overall goal of this study is to develop, adapt and evaluate an intergenerational prevention intervention, named "Wakȟáŋyeža (Little Holy One)," with Native American caregivers on a Northern Plains reservation and the…
- Conditions
- Suicide, Trauma, Psychological, Parenting
- Trial name
- NCT04201184
- Testing
- Newly created cultural components, adapted Family Spirit lessons, adapted CETA modules, Active nutrition control
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Nicotine Dependence, Nicotine Withdrawal
Human Laboratory Study of Varenicline and Bupropion for Nicotine Dependence
The objective of this proposal is to elucidate effects of bupropion SR + varenicline on smoking-cessation related processes in early abstinence using a human laboratory model.
- Trial name
- ChanBan (NCT00749658)
- Testing
- Bupropion, Varenicline
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Major Depressive Disorder, Post Traumatic Stress Disorder
Ketamine Safety and Tolerability in Psychiatric Inpatient Care (KetGD)
This observational registry aims to collect real-world data on ketamine use in psychiatric inpatients within a regional tertiary-reference center.
- Conditions
- Major Depressive Disorder, Post Traumatic Stress Disorder, Obsessive-Compulsive Disorder, Somatoform Disorders
- Trial name
- KetGD (NCT05565352)
- Testing
- Ketamine Hydrochloride
- Where
- Poland
- Volunteers
- 140 people
- Sponsor
- Medical University of Gdansk
Hydration Status, Psychosocial Stress
The Influence of Fluid Intake on Mental Performance
Over half of the adult population in Europe, Asia and Latin America fail to meet adequate water intake guidelines as advised by the European Food Safety Authority (EFSA; 2.5 and 2 litres/day for men and women, respectively coming…
- Conditions
- Hydration Status, Psychosocial Stress, Fluid Intake
- Trial name
- NCT07789847
- Testing
- Modifying daily total fluid intake
- Where
- United Kingdom
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Eating Behavior, Stress
The Gut Microbiota in Stress, Mood and Eating Behaviours.
Diet has a considerable influence on microbiota composition and the intake of either prebiotics (microbiota-specific food or probiotics (live microbiota species) has been shown to induce positive effects in both anxiety and…
- Conditions
- Eating Behavior, Stress, Mood
- Trial name
- NCT03482258
- Testing
- Prebiotic, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Roehampton
PTSD, Depression
Participatory System Dynamics vs Usual Quality Improvement: Staff Use of Simulation as an Effective, Scalable and Affordable Way to Improve Timely Mental Health Care?
Evidence-based VA care is best for meeting Veterans' mental health needs, such as depression, PTSD and opioid use disorder, to prevent suicide or overdose. But some key evidence-based practices only reach 3-28% of patients.
- Conditions
- PTSD, Depression, Opioid Use Disorder
- Trial name
- NCT04208217
- Testing
- Modeling to Learn (MTL), Usual quality improvement (QI)
- Where
- United States
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
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