Clinical trials: Mental Test
Stress Disorders, Post-Traumatic, Helping Behavior
Clinical Trial of a Supporter-Targeted Intervention to Improve Outcomes in Recent Sexual Assault Survivors
Communication and Recovery Enhancement (CARE) is a 2-session early intervention for survivors of recent sexual assault and their supporters that aims to improve supporters' ability to respond effectively.
- Conditions
- Stress Disorders, Post-Traumatic, Helping Behavior, Help-Seeking Behavior, Stress
- Trial name
- CARE (NCT05345405)
- Testing
- Dyadic CARE, Supporter-Only CARE
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Washington
Bipolar Disorder
Aripiprazole in Children and Adolescents With Bipolar I Disorder
The purpose of this trial is to test the safety and efficacy of two doses of aripiprazole in child and adolescent patients with bipolar I disorder, manic or mixed episode with or without psychotic features.
- Trial name
- NCT00110461
- Testing
- Aripiprazole
- Where
- 53 sites in United States
- Volunteers
- 296 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Reading Disability, Dyslexia
Eye Movements and Reading Disabilities
The mechanism of the eye movement anomalies seen in dyslexic patients is not well defined. Some optometrists use observational eye movement tests as screening devices for dyslexia and advocate eye movement therapy as a treatment…
- Trial name
- EOMRD (NCT01860027)
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Scripps Health
Schizophrenia
A Trial to Test the Effects of Other Drugs on SEP-380135 in Healthy Men and Women
The purpose of this study is to assess the effect of cytochrome P450 isoenzyme 2D6 (CYP2D6) inhibition by quinidine on the pharmacokinetic (PK) parameters of a single dose SEP-380135 in healthy adult participants.
- Trial name
- NCT07305779
- Testing
- SEP-380135, Quinidine Gluconate
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Chronic Pancreatitis, Pain Syndrome
Personalized Education and Pain Response in Chronic Pancreatitis
Pain mechanisms in chronic pancreatitis (CP) are heterogeneous and includes nociception, pancreatic neuropathy and central neuropathy/neuroplasty.
- Conditions
- Chronic Pancreatitis, Pain Syndrome, Depression, Anxiety
- Trial name
- PEPCP (NCT04654377)
- Testing
- Personalised education
- Where
- India
- Volunteers
- 114 people
- Sponsor
- Asian Institute of Gastroenterology, India
Alzheimer Disease, Mild Cognitive Impairment
Quality Improvement PrecivityAD Clinician Survey (QUIP I)
There is an important unmet need for timely, non-invasive, and low-burden evaluation of patients presenting with mild cognitive impairment (MCI) and early dementia.
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Dementia, Cognitive Decline
- Trial name
- QUIP I (NCT05477056)
- Testing
- PrecivityAD blood test
- Where
- United States
- Volunteers
- 366 people
- Sponsor
- C2N Diagnostics
Alcohol Use Disorder, HIV-infection/Aids
Development of an Intervention to Reduce Heavy Drinking and Improve HIV Care Engagement Among Fisherfolk in Uganda
Fisherfolk are a high risk population for HIV and are prioritized to receive antiretroviral treatment (ART) in Uganda, but risky alcohol use among fisherfolk is a barrier to HIV care engagement; multilevel factors influence…
- Trial name
- NCT03919695
- Testing
- Kisoboka: Behavioral and Structural Intervention, Screening and Referral
- Where
- Uganda
- Volunteers
- 160 people
- Sponsor
- San Diego State University
Dementia, Memory Impairment
Cultural and Linguistic Adaptation and Normative Study of the Turkish Version of the Free and Cued Selective Reminding Test: 16-Word Version (FCSRT-T)
An Adaptation Study of Free and Cued Selective Reminding Test in Turkish
- Trial name
- FCSRT-T (NCT05756231)
- Testing
- SIHT-16
- Where
- Turkey (Türkiye)
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Healthy
Testing the Interactive Effects of Delta-9-Tetrahydrocannabinol and Pregnenolone
The overall purpose of this study is to examine the effect of pregnenolone (PREG) on the acute psychosis-like and cognitive effects of Delta-9-tetrahydrocannabinol (THC).
- Trial name
- THC-Preg (NCT02576912)
- Testing
- Active Delta-9-THC, Active Pregnenolone
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Yale University
Opioid Misuse, Chronic Pain
Consensus-based Algorithms to Address Opioid Misuse Behaviors Among Individuals Prescribed Long-term Opioid Therapy
The NIH Helping to End Addiction Long-term (HEAL) initiative has identified a critical next step to addressing the opioid crisis: improving treatments for opioid misuse behaviors (e.g., using more opioids than prescribed, illicit…
- Trial name
- NCT05182606
- Testing
- Pilot study of algorithms implementation package
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Mild Cognitive Impairment, Cognitive Impairment
SNIFF - 3-Week Aptar CPS Device
The SNIFF 3-Week Aptar Device study will involve using a device to administer insulin or placebo through each participant's nose or intra-nasally. Insulin is a hormone that is produced in the body.
- Conditions
- Mild Cognitive Impairment, Cognitive Impairment, Alzheimer Disease, Early Onset
- Trial name
- NCT05006599
- Testing
- Insulin (Humulin® R U-100), Aptar Pharma CPS Intranasal Delivery Device
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Bipolar Disorder, Major Depressive Disorder
Clinical Validation Study for EDIT-B Test: an Aid for Differential Diagnosis of Bipolar Disorder, Based on RNA Editing Blood Biomarkers
Differentiation between major depressive disorder (MDD) and bipolar disorder (BD) as soon as possible in the patient journey represents a major clinical issue.
- Trial name
- EDIT-B (NCT05603819)
- Testing
- EDIT-B
- Where
- 4 sites in Denmark, France and 1 more
- Volunteers
- 418 people
- Sponsor
- Alcediag
Nurse's Role, Pain Management
Effect of Virtual Reality on Pain and Anxiety During Pap Smear Testing
This randomized controlled pretest-posttest experimental study aims to evaluate the effect of virtual reality (VR) on pain and anxiety levels experienced during Pap smear sampling.
- Conditions
- Nurse's Role, Pain Management, Cervical Cancer Screening, Anxiety
- Trial name
- NCT07462039
- Testing
- Virtual Reality
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Anxiety, Depression
Community Clinic Test of Youth Anxiety Treatment
Structured, manualized treatments have been developed for numerous mental health problems and disorders among children and adolescents, and a number of these have shown strong beneficial effects in clinical trials.
- Trial name
- YADS (NCT01005836)
- Testing
- Cognitive behavioral therapy for youth anxiety, Usual clinic care, Cognitive behavioral treatment for youth depression
- Volunteers
- 105 people
- Sponsor
- Harvard University
Obesity
Binge Eating, Depression and Anxiety Outcomes After Sleeve Gastrectomy Versus Gastric Bypass: A Cohort Study
The goal of this clinical trial is to learn if the type of weight-loss surgery (sleeve gastrectomy or gastric bypass) affects binge eating, depression, and anxiety in adults with severe obesity.
- Trial name
- NCT07600411
- Testing
- Laparoscopic Sleeve Gastrectomy, Gastric Bypass
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Obsessive-Compulsive Disorder
Transcranial Direct Current Stimulation Augmented Exposure and Response Prevention for Obsessive-Compulsive Disorder
This study is investigating whether combining noninvasive brain stimulation with behavior therapy can help to improve outcomes for obsessive-compulsive disorder (OCD).
- Trial name
- NCT02329587
- Testing
- ERP plus tDCS
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Butler Hospital
Body Dysmorphic Disorders
Smartphone-Administered App Treatment for Adults With Body Dysmorphic Disorder
The investigators are developing and testing a Smartphone-based cognitive behavioral therapy (CBT) "app" for body dysmorphic disorder (BDD).
- Trial name
- NCT03221738
- Testing
- App-Based Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Massachusetts General Hospital
Postoperative Delirium
Prevention of Postoperative Delirium in Elderly Patients
Prevention of Postoperative Delirium in the care of Elderly Patients. A Monocentric, Prospective Intervention Study With the Question of Whether the Incidence, Length and Severity of Postoperative Delirium Can be Reduced by…
- Trial name
- PODproject (NCT06248684)
- Testing
- standardized prevention and therapy measures
- Volunteers
- 15,000 people
- Sponsor
- Technical University of Munich
Breast Cancer
Testing Digital Breast Tomosynthesis vs. Regular Mammogram in Detecting Breast Cancer in Women Having Screening Mammogram
To compare DBT and FFDM for screening effectiveness in women who present for screening mammography with respect to screening recall rate.
- Trial name
- NCT00535678
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- GE Healthcare
Alzheimer's Disease
A Study of 18F-AV-45 in Alzheimer's Disease (AD) and Healthy Volunteers
This study will test if two AV-45 PET scans up to 4 weeks apart in AD subjects and healthy volunteers provide the same results. The study will also test two different AV-45 injection methods in a small subgroup of enrolled AD…
- Trial name
- NCT01565343
- Testing
- florbetapir F 18
- Where
- 4 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Avid Radiopharmaceuticals