Clinical trials: Mental and Behavioral Disorders
Intellectual Disability
Physical Activity, mHealth and Intellectual Disability - a Pilot Study
The main objective of this pilot study is to assess distant procedures, study experiences and feasibility of a planned randomized controlled trial investigating the use of a mHealth support tool on physical activity for…
- Trial name
- NCT04929106
- Testing
- mHealth support tool
- Where
- Norway
- Volunteers
- 9 people
- Sponsor
- University Hospital of North Norway
Attention Deficit/Hyperactivity Disorder
An SMS Intervention to Improve Adherence to Stimulant Medications in Adults With ADHD
This study will assess the efficacy of the text messaging (SMS-based) disease management intervention to improve adherence to stimulants in adults with Attention Deficit/Hyperactivity Disorder (ADHD).
- Trial name
- NCT04189536
- Testing
- SMS Intervention
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Massachusetts General Hospital
Major Depressive Disorder
Biomarkers of Social Sensitivity in Major Depression
Major depression disorder (MDD) is a frequent and disabling mental disorder with great risk of recurrence and chronicity. Interpersonal factors are among the strongest predictors of the course and duration of an episode of…
- Trial name
- SENSO (NCT02214511)
- Testing
- emotional facial stimuli, Cyberball game
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Attention Deficit Hyperactivity Disorder (ADHD)
Impact of Structured Exercise Programs on Cognitive, Motor and Behavioral Outcomes in Children With ADHD
The purpose of this study is to investigate the effects of structured exercise interventions (Gince Zumba and Square Stepping) on cognitive, motor and behavioral functions of children diagnosed with Attention Deficit…
- Trial name
- ADHD (NCT07376863)
- Testing
- Gince Zumba Exercise, Square Stepping Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Cukurova University
Perinatal Depression, Affective Disorder
Validation of the French Version of the Perinatal Assessment of Paternal Affectivity (PAPA)
The transition to parenthood is a critical period for both the woman and her partner, and this can affect the mental health of the parents.
- Conditions
- Perinatal Depression, Affective Disorder, Fathers
- Trial name
- French-Papa (NCT06594263)
- Where
- France
- Volunteers
- 343 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Depressive Disorder
An Eight-week Study to Evaluate the Efficacy and Safety of Saredutant in Patients With Depression
The purpose of the study is to evaluate the efficacy and safety of saredutant (or SR48968C) in patients with depression. The primary objective is to evaluate the efficacy of a 100 mg dose of saredutant compared to placebo in…
- Trial name
- NCT00250614
- Testing
- Saredutant succinate (SR48968C)
- Where
- United States
- Volunteers
- 452 people
- Sponsor
- Sanofi
Breast Cancer
Online Stress Management and Coping Skills Training for Women With Breast Cancer
Stress Management interventions have been shown to decrease cancer-related distress, foster emotional growth and improve immune functioning during treatment for breast cancer.
- Trial name
- NCT01335152
- Testing
- Coping with Breast Cancer web-based workbook
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Talaria, Inc
Trauma Injury, Depression
Therapy Dog Visits for Patients Hospitalized With Traumatic Injuries
Animal assisted therapy (AAT) with dogs has been shown to be beneficial for a wide range of patients with both acute and chronic illnesses, including spinal cord injuries, heart failure, myocardial infarctions, strokes, cancer…
- Conditions
- Trauma Injury, Depression, Anxiety, Anger
- Trial name
- NCT06812247
- Testing
- Therapy dog visits, Dog handler visits
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Boston Medical Center
Incontinence
Efficacy of Functional Magnetic Stimulation in Urinary Incontinence
Functional Magnetic Stimulation (FMS) appears to modulate autonomic and somatic nervous systems that innervate the lower urinary tract.
- Trial name
- FMS (NCT02091947)
- Testing
- FMS (Magstim rapid2)
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- vghtpe user
Melanoma
Studying Quality of Life Inclusive of Mental Health and Cognitive Behavioral Therapy for Cancer Distress for the Improvement of Quality of Life in Stage III-IV Melanoma Patients
This clinical trial studies how people feel and live during the first two years after being treated for melanoma and whether cognitive behavioral therapy for cancer distress (CBT-C) works to improve quality of life in patients…
- Trial name
- NCT07379138
- Testing
- Best Practice, Cognitive Behavior Therapy, Electronic Health Record Review
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Mayo Clinic
Anxiety, Depression
Mobile Mental Health Stigma Reduction Intervention Among Black Adults
Major depressive and anxiety disorders are highly prevalent in the general population and are a leading cause of disability. Black adults have a high burden of depression and anxiety.
- Conditions
- Anxiety, Depression, Health Knowledge, Attitudes, Practice, Stigmatization
- Trial name
- NCT06316804
- Testing
- Video Intervention 1, Video Intervention 2, Video Intervention 3
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Massachusetts General Hospital
Acceptance and Commitment Therapy, Caregiver Burden
Acceptance and Commitment Therapy (ACT) Tele-Counselling
A randomized 2-group controlled trial will be conducted to explore the potential effect and potential feasibility of a new Acceptance and Commitment Therapy (ACT) tele-counselling program to improve mental health services for…
- Conditions
- Acceptance and Commitment Therapy, Caregiver Burden, Digital Health, Technology
- Trial name
- NCT05385458
- Testing
- ACT Intervention, Usual Care
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of New Brunswick
Smoking Cessation, Cardiovascular Disease
What Are the Effects of Varenicline Compared With Nicotine Replacement Therapy on Long Term Smoking Cessation and Clinically Important Outcomes?
Introduction: Smoking is a major avoidable cause of ill-health and premature death. Treatments that help patients successfully quit smoking have an important effect on health and life expectancy.
- Conditions
- Smoking Cessation, Cardiovascular Disease, Respiratory Disease, Myocardial Infarction
- Trial name
- NCT02681848
- Testing
- Varenicline, Nicotine replacement therapy
- Volunteers
- 180,000 people
- Sponsor
- University of Bristol
Bipolar Depression
Memantine Augmentation of Lamotrigine Incomplete-Response in Bipolar Depression
The purpose of this study is to investigate whether addition of memantine to bipolar depression patients who have had an incomplete response to lamotrigine (Lamictal) which is frequently used to treat bipolar depression in the…
- Trial name
- NCT00305578
- Testing
- Memantine
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Indiana University
Attention Deficit Hyperactivity Disorder
Development of Virtual Reality-based Interventions to Strengthen Cognitive Skillsets Related to Attention Deficit Hyperactivity Disorder (ADHD): A Pilot Phase I and Randomized Controlled Phase II Trial
Background: Children with attention deficit hyperactivity disorder (ADHD) often have cognitive problems. It may be hard for them to control their behaviors, concentrate for long periods, or make decisions.
- Trial name
- NCT05608434
- Testing
- Non-adaptive Floreo VR control, Floreo Virtual Reality application
- Where
- United States
- Volunteers
- 219 people
- Sponsor
- National Institute of Mental Health (NIMH)
Borderline Personality Disorder, Suicide
Comparing Treatments for Self-Injury and Suicidal Behavior in People With Borderline Personality Disorder
This study will compare the effectiveness of two treatments, dialectical behavior therapy versus fluoxetine with clinical management, for reducing the risk of self-injury and suicidal behavior in people with borderline…
- Trial name
- NCT00834834
- Testing
- Fluoxetine, DBT, Citalopram
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- New York State Psychiatric Institute
Diabetes, Depression
e-Pharmacovigilance II - Surveillance for Safety and Effectiveness - Calling for Earlier Detection of Adverse Reactions
Specific Aim 1: To develop a patient-reported, EHR-integrated system to actively monitor the safety and effectiveness of treatment for patients taking FDA-approved medications for one of four common chronic conditions (diabetes…
- Conditions
- Diabetes, Depression, Insomnia, Hypertension
- Trial name
- CEDAR (NCT02087293)
- Testing
- Intervention arm - automated call and phone-based pharmacist counseling
- Where
- United States
- Volunteers
- 38,400 people
- Sponsor
- Brigham and Women's Hospital
Attention-Deficit/Hyperactivity Disorder
Supplementation of Phosphatidylserine (PS) and n-3 Long Chain Fatty Acids (EPA, DHA) in Children With ADHD
To determine whether supplementation of omega-3 long-chain polyunsaturated fatty acid conjugated to phosphatidylserine rather than triglycerides (fish oil) could affect Attention-deficit/hyperactivity disorder symptoms in…
- Trial name
- NCT00382616
- Testing
- Phosphatidylserine-Omega3
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Very Low Birth Weight Infants
Efficacy of Multiple Strain Probiotics Reduces the Neurobehavioral Disorder in Premature Very Low Birth Weight Infants
The management protocols, clinical practices, equipment, infrastructure, and key personnel in NICU are unchanged during the study period.
- Trial name
- NCT03858816
- Testing
- Mixture probiotics
- Where
- Taiwan
- Sponsor
- China Medical University Hospital
Substance Abuse, HIV
Electronic SBI(RT) for MSM in Argentina
The main goal of this pilot randomized controlled trial (RCT) with 200 participants is to establish the processes and procedures for a subsequent large-scale efficacy trial of an electronic-Screening, Brief Intervention, Referral…
- Trial name
- NCT05542914
- Testing
- electronic screening and brief intervention., Phase 2: Assessment Only
- Where
- Argentina
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Florida State University
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