Clinical trials: Mental and Behavioral Disorders
Severe Mental Disorder
Aerobic, Resistance and Inspiratory Muscle Training in Adults With Severe Mental Disorder
People with severe mental disorder, such as schizophrenia, bipolar disorder or major depression, tend to have poorer physical health and a shorter life expectancy than the general population.
- Trial name
- NCT07758049
- Testing
- Supervised multicomponent exercise programme
- Where
- Spain
- Volunteers
- 49 people
- Sponsor
- Universidad Pablo de Olavide
Schizophrenia
Mental Health During the Whole Life Cycle of Community Patients With Schizophrenia
Schizophrenia is one of the components of severe mental disorders. It has the characteristics of prolonged course, low cure rate, high recurrence rate and high disability rate.
- Trial name
- NCT05159349
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Shanghai Mental Health Center
COVID-19
COVID-19 and Brain: Cognition and Mental Health
The main goal of DIANA is to investigate the potential discriminative power of multimodal biomarkers in COVID adverse outcomes. The study of the neuropathological underlying mechanisms in COVID from a translational approach at…
- Trial name
- DIANA (NCT05307549)
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Weight Loss, Food Habits
School Intervention With Daily Physical Activity and Healthy Food for Students With an Intellectual Disability.
A whole of school intervention with daily physical activity and healthy food for students with intellectual disabilities. The aim is to provide plenty of concrete examples of healthy life style choices and using school personnel…
- Conditions
- Weight Loss, Food Habits, Mental Retardation
- Trial name
- NCT01291238
- Testing
- Healthier, Smarter, Happier
- Where
- Sweden
- Volunteers
- 145 people
- Sponsor
- Karolinska Institutet
Nicotine Dependence, Nicotine Withdrawal
Human Laboratory Study of Varenicline and Bupropion for Nicotine Dependence
The objective of this proposal is to elucidate effects of bupropion SR + varenicline on smoking-cessation related processes in early abstinence using a human laboratory model.
- Trial name
- ChanBan (NCT00749658)
- Testing
- Bupropion, Varenicline
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Human Immunodeficiency Virus, Alcohol-Related Disorders
Project Khanya: Peer-Delivered Intervention to Improve HIV Medication Adherence and Substance Use in South Africa
The purpose of this study is to evaluate a stepped care behavioral intervention for HIV medication adherence and substance use ("Khanya") integrated into an HIV primary care setting in South Africa.
- Conditions
- Human Immunodeficiency Virus, Alcohol-Related Disorders, Drug Use, Substance Use
- Trial name
- NCT05933226
- Testing
- Khanya
- Where
- South Africa
- Volunteers
- 160 people
- Sponsor
- University of Maryland, College Park
Depression
Comparison of Krill and Fish Oil on Clinical and Biochemical Outcomes in Depression
The Omega-3 polyunsaturated fatty acids (n-3 PUFA), associated with fish oil, has been one of the most studied non-pharmacological subjects for its effect on Major Depression Disorder (MDD).
- Trial name
- NCT06414226
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people
- Sponsor
- Firat University
Marijuana Use, Cannabis Use
THC + CBD and Memory Study
Memory deficits are one of the most consistently observed cognitive effects of marijuana use. There is evidence that some decrements attributable to the primary psychoactive ingredient, delta-9-tetrahydrocannabinol (THC), may be…
- Conditions
- Marijuana Use, Cannabis Use, Cannabis Intoxication
- Trial name
- NCT04855526
- Testing
- High THC/No CBD Marihuana, High THC/High CBD Marihuana, No THC/No CBD Marihuana
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Attention Deficit Hyperactivity Disorder
Investigation of Strategies to Reduce the Impact of the Relative Age Effect in Kindergarten
There is now clear evidence that children entering kindergarten, that are relatively young for the grade (e.g., born in the months immediately preceding the school entry cut-off) are at significantly more risk for receiving an…
- Trial name
- NCT05142826
- Testing
- Relative Age Effect Intervention, School as Usual
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Florida International University
Depression
A Family Depression Prevention Program
The primary aim is to prevent depression in youth and parents in a single, integrated family intervention. Hypothesis 1a: Children in the Family Depression Prevention (FDP) program will have significantly lower levels of…
- Trial name
- FDP (NCT02021578)
- Testing
- Family Cognitive Behavioral Prevention, Written information
- Where
- 2 sites in United States
- Volunteers
- 304 people
- Sponsor
- Vanderbilt University
Attention Deficit Hyperactivity Disorder
Treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) With Atomoxetine in Young Adults and Its Effects on Functional Outcomes
This study will evaluate atomoxetine's efficacy in treating attention-deficit/hyperactivity disorder (ADHD) symptoms and atomoxetine's effect on functional outcomes in young adults.
- Trial name
- NCT00510276
- Testing
- Atomoxetine hydrochloride
- Where
- 29 sites in United States, Puerto Rico
- Volunteers
- 445 people
- Sponsor
- Eli Lilly and Company
ADHD, Attention
Effects of Cognitive Training on Academic Task Performance in Attention Deficit Hyperactivity Disorder (ADHD)
Impaired WM is a central deficit in ADHD. A computerized training program, Cogmed, has been shown to increase WM capacity in children with ADHD.
- Trial name
- Cog-RAST (NCT01124721)
- Testing
- Cognitive training
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of California, Davis
Anxiety, Depression
Connecticut Child STEPs
Connecticut Child STEPS is a randomized controlled trail investigating the effectiveness of MATCH-ADTC in treating anxiety, depression, trauma, and/or behavioral problems in children seeking services at four Department of…
- Conditions
- Anxiety, Depression, Trauma, Behavior Problems
- Trial name
- NCT03153904
- Testing
- Modular Approach to Therapy for Children with Anxiety, Depression, Trauma, and Conduct Problems, Monitoring and Feedback System
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Harvard University
Depression, Treatment Resistant Depression
Studying the Health of Asians to Advance Knowledge, Treatments, and Interventions for Depression
SHAKTI (from the Sanskrit word for "power") is a 5-year natural history, longitudinal, prospective study of a cohort of 6,000 participants that will help uncover the socio-demographic, lifestyle, clinical, psychological, and…
- Conditions
- Depression, Treatment Resistant Depression, Mood Disorders, Bipolar Disorder
- Trial name
- SHAKTI (NCT06002204)
- Testing
- Observational Study
- Where
- United States
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Social Behaviour, Brain Neoplasms
Social Cognition in Children Treated for a Brain Tumour
There is ample evidence that children treated for a brain tumour (BT) often develop deficits in social and emotional functioning. The investigators wish to examine the cause of these deficits, i.e.
- Conditions
- Social Behaviour, Brain Neoplasms, Cystic Fibrosis
- Trial name
- NCT01599052
- Where
- 4 sites in Belgium, Netherlands
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
ADHD, ADHD - Combined Type
the Cogmed Program for Youths With ADHD
The primary objective of this study was to examine the effects of the Cogmed training program on working memory among youths 7 to 13 years old, while controlling presence and presentation of ADHD-related comorbidity.
- Trial name
- ADHDtraining (NCT03335748)
- Testing
- Cognitive training Cogmed program
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Université du Québec a Montréal
ADHD
Neurofeedback Intervention on the Development of ADHD in Children at Risk
Forty children considered at risk for ADHD (subclinical ADHD) will be randomized to either a neurofeedback intervention or waiting list.
- Trial name
- NCT01692548
- Testing
- Neurofeedback
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Mental Health Wellness 1, COVID
Telepsychoeducation for the Prevention of Emotional Distress in Professionals and Students From Essential Services in the Context of COVID-19
A pragmatic superiority randomized controlled trial comparing Telepsychoeducation plus personalized videos vs. Telepsychoeducation without personalized videos for the prevention of future emotional distress in professionals and…
- Conditions
- Mental Health Wellness 1, COVID, Emotional Distress, Depressive Symptoms
- Trial name
- NCT04632082
- Testing
- Telepsychoeducation with personalized videos, Telepsychoeducation without personalized videos
- Where
- Brazil
- Volunteers
- 2,200 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Smith-Magenis Syndrome (SMS)
Natural History Study of Smith-Magenis Syndrome
This study will examine how a rare disease called Smith-Magenis syndrome (SMS) affects people and how they change over time. SMS is caused by a small chromosome 17p11.2 deletion (missing piece).
- Trial name
- NCT00013559
- Where
- United States
- Volunteers
- 593 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Alcohol Use Disorder, Problem Drinking
Development and Effectiveness of an Alcohol Intervention Program for Adults Under Probation
The aim of this study is to develop and evaluate the effectiveness of an alcohol-specific intervention program for adult individuals on probation who have problems related to alcohol use.
- Conditions
- Alcohol Use Disorder, Problem Drinking, Psychosocial Intervention
- Trial name
- PROB-AIP (NCT06966180)
- Testing
- Alcohol Intervention Program (AIP)
- Where
- Turkey (Türkiye)
- Volunteers
- 115 people
- Sponsor
- Mine Pazarcikci
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