Clinical trials: Mental and Behavioral Disorders
Pain, Anxiety
Pain Processing in Anxiety and Depression
The purpose of the study is to investigate pain, anxiety and depression in patients with panic anxiety disorders without pain or depression without pain compared with healthy volunteers
- Conditions
- Pain, Anxiety, Depression
- Trial name
- NCT00560196
- Testing
- Observation
- Where
- Denmark
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Danish Pain Research Center
Quality of Life, Sexual Function
Effects of Structured Rehabilitation Program on Quality of Life in Rectal Cancer Patients- a Randomized Controlled Trial
Quality of life after rectal surgery is reported to be impaired. Side effects of surgery and/or neoadjuvant treatment as functional disturbances like sexual dysfunction, urinary incontinence, anal incontinence or stoma problems…
- Conditions
- Quality of Life, Sexual Function, Urinary Incontinence, Anal Incontinence
- Trial name
- NCT00895388
- Testing
- Structured Rehabilitation program
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
PTSD, Depression
Participatory System Dynamics vs Usual Quality Improvement: Staff Use of Simulation as an Effective, Scalable and Affordable Way to Improve Timely Mental Health Care?
Evidence-based VA care is best for meeting Veterans' mental health needs, such as depression, PTSD and opioid use disorder, to prevent suicide or overdose. But some key evidence-based practices only reach 3-28% of patients.
- Conditions
- PTSD, Depression, Opioid Use Disorder
- Trial name
- NCT04208217
- Testing
- Modeling to Learn (MTL), Usual quality improvement (QI)
- Where
- United States
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Autism Spectrum Disorder, Food Selectivity
Clinical Trial of "Exploradores de Sabores" to Improve Food Selectivity in ASD Kids
The goal of this randomized, single-blind clinical trial is to evaluate the effectiveness of the Exploradores de Sabores parent-mediated nutrition intervention in reducing food selectivity and improving dietary variety, mealtime…
- Trial name
- NCT07727018
- Testing
- Exploradores de Sabores Parent-Mediated Nutrition Intervention, Education as Usual (EAU)
- Where
- Mexico
- Volunteers
- 72 people
- Sponsor
- Universidad Autonoma de Baja California
Post COVID-19, Cognitive Dysfunction
Multimodal Investigation of Post COVID-19 in Females
The purpose of this study is to investigate the effects of transcutaneous vagus nerve stimulation (t-VNS) on Long Covid symptoms in females and to identify factors influencing susceptibility and recovery-particularly in the…
- Trial name
- NCT05225220
- Testing
- Parasym Device (of Parasym Ltd, UK) using Transcutaneous Vagus Nerve Stimulation (t-VNS)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Delirium, Agitation
Efficacy and Safety of Risperidone and Trazodone Monotherapy and Combination Therapy in Critically Ill Patients With Delirium
The purpose of this randomized clinical trial is to determine whether risperidone alone, trazodone alone, or a combination of risperidone and trazodone is superior for the treatment of ICU acquired delirium.
- Trial name
- NCT02118688
- Testing
- Risperidone, Trazodone
- Where
- United States
- Sponsor
- Rochester General Hospital
Depression, Anxiety, Physical Activity
Promoting Active Therapy: Path to Wellness
This project will examine changes in depression and anxiety following a 10-week intervention promoting nature-based physical activity in mental health settings.
- Conditions
- Depression, Anxiety, Physical Activity, Time in Nature, Self-Efficacy
- Trial name
- NCT06858189
- Testing
- Walk-and-talk therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Kansas State University
Behavior Problem, Development Delay
Norwalk Feasibility Study
The purpose of this study is two-fold: 1) to examine the feasibility of the Drop-In model of Family Nurture Intervention (FNI); and 2) to collect pilot data concerning the mother's response to the Drop-In model of FNI and short…
- Conditions
- Behavior Problem, Development Delay, Emotional Disturbances, Family Conflict
- Trial name
- NCT04048720
- Testing
- Family Nurture Intervention
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Columbia University
Stroke, Ischemic, Transient Ischemic Attack
Trajectories of Post-stroke Multidimensional Health
Stroke is thought to cause disability immediately after stroke followed by a 3-to-6-month recovery period, after which disability levels are supposed to stabilize unless recurrent events occur.
- Conditions
- Stroke, Ischemic, Transient Ischemic Attack, Adaptation, Psychological, Mental Health Impairment
- Trial name
- NeuroAdapt (NCT04704635)
- Where
- Germany
- Volunteers
- 330 people
- Sponsor
- University Medicine Greifswald
Stress Urinary Incontinence
Autologous Muscle Derived Cells Compared to Placebo for Urinary Sphincter Repair in Post-surgical Female Stress Incontinence
This study evaluates the efficacy and safety of Autologous Muscle Derived Cells for Urinary Sphincter Repair (AMDC-USR; generic name: iltamiocel) compared to a placebo in the reduction of stress incontinence episode frequency in…
- Trial name
- CELLEBRATE (NCT03104517)
- Testing
- AMDC-USR (iltamiocel)
- Where
- 21 sites in United States, United Kingdom
- Volunteers
- 96 people
- Sponsor
- Cook MyoSite
Pain, Anxiety State
App Delivered Brief Mindfulness Intervention for Surgical Patients
This will be a single-site, five-arm, parallel group randomized control trial involving patients undergoing knee or hip replacement surgery.
- Conditions
- Pain, Anxiety State, Depressive State
- Trial name
- NCT05433389
- Testing
- Breath Counting, Body Scan, Mindful Breathing
- Where
- United States
- Volunteers
- 823 people
- Sponsor
- University of Utah
Depression, Opioid Use
Opioid Treatment and Recovery Through a Safe Pain Management Program
Opioid prescription drug abuse has become a major public health concern in the United States with mortality rates from fatal overdoses reaching epidemic proportions.
- Conditions
- Depression, Opioid Use, Chronic Pain, Anxiety
- Trial name
- NCT03889418
- Testing
- Electronic medical recorded clinical decision support [EMR CDS], Stepped opioid collaborative care model [CCM]
- Where
- United States
- Volunteers
- 490 people
- Sponsor
- Ochsner Health System
Psychiatric Disorder, Cognition Disorder
MEOP - Multidimensional Evaluations in Oncological Psychiatry
Cancer is among the leading causes of morbidity and mortality worldwide, profoundly affecting patients' lives at every level, and its psychological and psychiatric impacts remain a major concern.
- Conditions
- Psychiatric Disorder, Cognition Disorder, Treatment Compliance, Adverse Drug Event
- Trial name
- MEOP (NCT07406113)
- Testing
- Psychiatric and neuropsychological evaluation through rating scales
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Anxiety Disorders
Anxiety in Older Veterans
Anxiety leads to poor quality of life, avoidance of activities, decreased social engagement, functional decline, and disability in older patients.
- Trial name
- BREATHE (NCT02400723)
- Testing
- Progressive Muscle Relaxation, Diaphragmatic Breathing
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- VA Office of Research and Development
Mild Cognitive Impairment (MCI)
Evaluation of the Effect of Healthy Lifestyle Intervention for Patients With Mild Cognitive Impairment
This clinical study aims to evaluate the feasibility and preliminary effectiveness of a comprehensive lifestyle intervention program for patients with mild cognitive impairment.
- Trial name
- NCT06942780
- Testing
- Exercise intervention, Social intervention, Dietary intervention
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Xuanwu Hospital, Beijing
Gulf War Illness, Insomnia
Cognitive Behavioral Therapy for Insomnia for Gulf War Illness
Sleep disturbance is a common complaint of Veterans with Gulf War Illness (GWI). Because there is clinical evidence that sleep quality influences pain, fatigue, mood, cognition, and daily functioning, this study will investigate…
- Trial name
- CBTi GWI (NCT02782780)
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBTi)
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- VA Office of Research and Development
Mental Disorders
The Western Norway Mental Health Interface Study on Referral Letters
The main object to this trial is to study the function of referral letters as a mean to coordinate the care process for adult people when referred from Primary Care to Specialised Mental Health Care.
- Trial name
- NCT01374035
- Testing
- Quality improvement intervention
- Where
- Norway
- Sponsor
- Helse Fonna
Nonverbal Communication, Critical Illness
Vidatalk Communication Application: Usability, Acceptability and Efficacy Study
This Phase II Small Business Technology Transfer Research (STTR) will deliver a comprehensive patient communication solution for communication-impaired patients in the intensive care unit that may help decrease days in delirium…
- Trial name
- NCT02921776
- Testing
- Aim 1 - VidaTalk - post-extubation, Aim 2 - VidaTalk - intubated, Aim 3 - VidaTalk tablet app
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- Ohio State University
Narcolepsy, REM Sleep Behavior Disorder
Investigation of Clinical Feature and Brain Function in Narcoleptic Patients
This study evaluates the PSG and cerebral metabolism and functions in narcolepsy with/without RBD
- Trial name
- NCT03376568
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Obsessive-Compulsive Disorder
Control and Reward Circuits in Obsessive Compulsive Disorder
The purpose of this study is to examine the brain functioning of OCD patients and healthy controls before and after treatment with Exposure and Response Prevention (EXRP) therapy.
- Trial name
- NCT02221518
- Testing
- Exposure & Response Prevention (EX/RP)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
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