Clinical trials: Mental and Behavioral Disorders
Radiation Toxicity, Chemotherapeutic Toxicity
Patients Referred to the Chronic Pain Unit for Palliative Treatment With Ozone Therapy Between 2022 and 2025
The main objective of this study is to analyze the impact on the health-related quality of life of patients with refractory symptoms, who have been referred to the HUGCDN Chronic Pain Unit for adjuvant palliative treatment with…
- Conditions
- Radiation Toxicity, Chemotherapeutic Toxicity, Chemotherapy-induced Peripheral Neuropathy, Delayed Wound Healing
- Trial name
- EPOOzo (NCT05417737)
- Testing
- Ozone therapy
- Where
- Spain
- Volunteers
- 105 people
- Sponsor
- Bernardino Clavo, MD, PhD
Neurologic Manifestations, Psychiatric Disorders
Cohort of Patients With Covid-19 Presenting Neurological or Psychiatric Disorders (CoCo-Neurosciences)
Covid-19 pandemic now affects more than two million people worldwide. The neurotropism of the virus is assumed by its frequent association with neurological symptoms (anosmia, ageusia, headaches) but the extent of the central or…
- Conditions
- Neurologic Manifestations, Psychiatric Disorders, COVID-19
- Trial name
- CoCo-Neuro (NCT04362930)
- Where
- France
- Volunteers
- 730 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Attention Deficit and Hyperactivity Disorder (ADHD), Attention Deficit Hyperactivity Disorder in Adults
The Effect of 5-hydroxytryptophan on ADHD Traits and Eye Movements
The aim of this project is to look at the impact of 5-Hydroxytryptophan (5-HTP) on distractibility. 5-HTP is the precursor to the neurotransmitter serotonin and is a chemical that the body produces naturally.
- Conditions
- Attention Deficit and Hyperactivity Disorder (ADHD), Attention Deficit Hyperactivity Disorder in Adults, Attention Deficits
- Trial name
- NCT07777328
- Testing
- 5-hydroxytryptophan (food supplement) 200mg, 5-hydroxytryptophan (food supplement) 300mg
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Internet Addiction
Effectiveness of Acceptance and Commitment Therapy in Promoting Mental Health of Emerging Adults With Internet Addiction
Internet addiction, a growing epidemic among young adults, significantly impairs mental health, emotional regulation, and overall well-being.
- Trial name
- NCT07750366
- Testing
- Acceptance and Commitment Therapy (ACT)
- Where
- Pakistan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- National University of Modern Languages
ADHD
The Effects of Yoga on Attention, Impulsivity and Hyperactivity in Pre-school Age Children
This pilot project will evaluate yoga as an intervention to improve attention and reduce challenging behaviors such as hyperactivity and impulsivity, rated by parent and teachers, in preschool age children with or "at risk" for…
- Trial name
- NCT02642666
- Testing
- Children's Yoga
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Bipolar Depression
Neurobiological Effects of Psilocybin in Treatment Resistant Bipolar Depression
This study is an open-label, single-arm, proof-of-concept study, wherein treatment resistant bipolar depression (TRBD) participants will receive one 25 mg dose of oral psilocybin accompanied by preparatory, monitoring, and…
- Trial name
- Psilo-BD (NCT06506019)
- Testing
- Psilocybin, Functional MRI
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University Health Network, Toronto
Bipolar Disorder
Adjunctive Isradipine for the Treatment of Bipolar Depression
This study investigates the medication isradipine, which is currently approved by the FDA to treat high blood pressure, in the treatment of depression in bipolar disorder.
- Trial name
- Isradipine (NCT01784666)
- Testing
- Isradipine
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Massachusetts General Hospital
Anxiety, Depression
CO-PARENT: COVID-19 - Parent Action in Response to Emotions and Needs for Treatment
The purpose of this research study is to collect information to better understand caregiver responses to COVID-19 stress and to help caregivers cope with these stressors.
- Conditions
- Anxiety, Depression, Traumatic Stress Disorder
- Trial name
- Co-PARENT (NCT04431856)
- Testing
- Unified Protocol for COVID-19 Parenting Stress (UP-COVID), SHG
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Miami
Executive Dysfunction
Effects of Atx and Oros-mph on Executive Functions
The aim of this study was to evaluate and compare the effects of Atomoxetine(ATX) and osmotic release oral system-methylphenidate (OROS-MPH) therapies on executive functions, activities, treatment response time and adverse…
- Trial name
- NCT02352051
- Testing
- Atomoxetine, methylphenidate
- Volunteers
- 43 people
- Sponsor
- TC Erciyes University
ADHD
Neurobiological Basis of Response to Vyvanse in Adults With ADHD: an fMRI Study of Brain Activation
The purpose of this study is to determine the effects of Vyvanse, an FDA approved medication used in the treatment of Attention Deficit Hyperactivity Disorder (ADHD), on brain activity in adults with attention-deficit…
- Trial name
- NCT01924429
- Testing
- Lisdexamfetamine
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Jeffrey Newcorn
Feeding and Eating Disorders of Childhood
Impact of the "Ten Steps for Healthy Feeding of Children Younger Than Two Years" in Health Centers
A cluster randomized field trial to evaluate the impact that training healthcare workers in healthy feeding practices has on the nutrition and health of children.
- Trial name
- NCT00635453
- Testing
- Dietary Advice
- Where
- Brazil
- Volunteers
- 715 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Autism
Treatment for Children With Autism and Anxiety
Children with high-functioning autism spectrum disorders (ASD) are at high risk for developing significant anxiety symptoms. Cognitive behavior therapies (CBT) are frequently used for children with anxiety symptoms with good…
- Trial name
- NCT01727466
- Testing
- Facing Your Fears
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Trauma and Stressor Related Disorders, Pediatric Cancer
Emotion and Symptom-Focused Engagement (EASE) for Caregivers
The goal of this Phase III randomized controlled trial is to evaluate the effectiveness of a novel psychotherapeutic intervention called Emotion and Symptom-focused Engagement (EASE) in parents caring for a child or adolescent…
- Conditions
- Trauma and Stressor Related Disorders, Pediatric Cancer, Caregiver Burden
- Trial name
- EASE (NCT06367556)
- Testing
- Emotion and Symptom-Focused Engagement (EASE)
- Where
- 2 sites in Canada
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Panic Disorder, Phobic Disorders
Threat-Avoidance Learning in Anxiety Patients
Anxiety disorders are characterized by exaggerated levels of fear that are not proportional to the actual level of threat. More specifically, anxiety patients have marked deficits in the downregulation of fear reactions during…
- Conditions
- Panic Disorder, Phobic Disorders, Stress Disorders, Traumatic
- Trial name
- AVOID (NCT02336802)
- Testing
- Avoidance experiment
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Eating Disorders, Maladaptive Personality Trait
MICBT for Non-underweight Adults With Eating Disorders
Eating disorders (ED) are severe but treatable conditions, but there are large margin for improvements in terms of efficacy and adherence.
- Conditions
- Eating Disorders, Maladaptive Personality Trait, Emotion Regulation, Personality
- Trial name
- MICBT-ED (NCT05503745)
- Testing
- CBT-F+MIT, CBT-E
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Centro Trattamento Integrato: Disturbi Alimentari e Obesita
Enuresis, Nocturnal
The Effect of Selecting Treatment With Desmopressin or Alarm to Children With Enuresis Based on Home Recordings.
The aim of this study is to investigate the importance of clinical characterization of children with monosymptomatic nocturnal enuresis (MNE) in order to improve treatment efficacy.
- Trial name
- DRYCHILD (NCT03389412)
- Testing
- Desmopressin, Conditional alarm
- Where
- 6 sites in Belgium, China and 2 more
- Volunteers
- 324 people
- Sponsor
- University of Aarhus
Alcohol Dependence, Alcohol Abuse
Motivation in Alcohol Treatment Facilities
The purpose of this study is to determine if and to what extend a composite measure of treatment motivation and behavior change motivation predicts alcohol treatment success.
- Trial name
- NCT00424112
- Where
- 2 sites in Germany
- Volunteers
- 450 people
- Sponsor
- University Medicine Greifswald
Cognitive Impairment
The Effect of Exercise on Cognition in Older Adults At-risk for Diabetes: A Feasibility Pilot Study
Older adults with type 2 diabetes experience cognitive decline and are at higher risk for developing dementia. Consequently, older adults at-risk for developing type 2 diabetes (based on body mass, glucose levels) are at higher…
- Trial name
- NCT03254381
- Testing
- Resistance Training, Balance and Tone Training
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Western University, Canada
Idiopathic Pulmonary Fibrosis, Chronic Obstructive Pulmonary Disease
Coping Strategies Within Pulmonary Rehabilitation in Patients With IPF and COPD
The aim of this prospective observational trial is to evaluate the influence of Coping strategies on pulmonary rehabilitation outcomes like 6-minute walk distance and Quality of life.
- Trial name
- NCT04257630
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Hazardous Alcohol Use
PrEP and Alcohol - Enhancing HIV Pre-Exposure Prophylaxis (PrEP)
The present investigation entails a pilot randomized controlled trial to explore whether a stand-alone, alcohol-reduction, brief intervention (with a module on substance use and depression) would be feasible, acceptable, and…
- Trial name
- NCT05097430
- Testing
- Alcohol-focused brief intervention
- Where
- 3 sites in Canada
- Volunteers
- 122 people
- Sponsor
- Centre for Addiction and Mental Health
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