Clinical trials: Mental and Behavioral Disorders
Opioid Use Disorder, Suicidal Ideation
Ketamine for OUD and Suicidal Ideation in the ED
This is a pilot, double-blind, placebo-controlled randomized clinical trial of individuals with opioid use disorder (OUD) with suicidal ideation in the emergency department (ED) to receive either a single infusion of ketamine…
- Trial name
- NCT06111339
- Testing
- Ketamine, Saline Solution
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Brigham and Women's Hospital
Feeding and Eating Disorders, Child Behavior Problem
A FOUR SESSION ONLINE OCCUPATIONAL THERAPY GROUP TRANINIG FOR MOTHERS OF CHILDREN WITH FEEDING PROBLEMS
Feeding problems such as selective eating, loss of appetite, and mealtime behavior problems are common in childhood. Parents play a primary role in learning about feeding, and difficulties experienced in this process may cause…
- Conditions
- Feeding and Eating Disorders, Child Behavior Problem, Feeding Behavior, Online Intervention
- Trial name
- NCT06086639
- Testing
- Online Occupational Therapy Group Training
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Ankara Medipol University
mHealth, Eating Disorder
Evaluation of a Program for Eating Disorders That Combines Cognitive-behavioral Therapy With Online Psychological Treatment
The purpose of this project is to conduct a multicentre, randomized controlled trial (RCT) with 250 patients diagnosed with an eating disorder (ED).
- Trial name
- NCT03197519
- Testing
- TCApp, TAU
- Where
- 4 sites in Spain
- Volunteers
- 108 people
- Sponsor
- Universitat Oberta de Catalunya
Cancer
Ketamine Hydrochloride and Best Pain Management in Treating Cancer Patients With Neuropathic Pain
RATIONALE: Ketamine hydrochloride may lessen neuropathic pain in patients with cancer. It is not yet known whether ketamine hydrochloride given together with the best pain management is more effective than a placebo given…
- Trial name
- NCT01316744
- Testing
- ketamine hydrochloride, pharmacogenomic studies, questionnaire administration
- Where
- 3 sites in United Kingdom
- Volunteers
- 214 people
- Sponsor
- University of Glasgow
Stress, Work Related Stress
Emergency Medical Staff Workload Analysis
The aim of this study is to identify trauma determinants and leverage this understanding to develop solutions applicable to the prevention and treatment of PTSD among emergency medical personnel.
- Conditions
- Stress, Work Related Stress, PTSD, Mental Stress
- Trial name
- NCT06302764
- Testing
- Qualitative & Quantitative Research
- Where
- 3 sites in Poland, Portugal and 1 more
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Quality of Life, Post ICU Discharge
Study in Intensive Care Follow-up Programme in Improving Long-term Outcomes of ICU Survivors
Study Hypothesis: Critical illness is associated with long-term medical and psychological sequelae that can impact the professional and private life.
- Trial name
- SUIVI-REA (NCT01796509)
- Testing
- Medical, psychological, social
- Where
- France
- Volunteers
- 545 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Prader-Willi Syndrome
A Study of Pitolisant in Patients With Prader-Willi Syndrome
This is a Phase 3, randomized, double-blind, placebo-controlled, multicenter, global clinical study to assess the efficacy and safety of pitolisant in patients living with Prader-Willi syndrome.
- Trial name
- NCT06366464
- Testing
- Pitolisant tablet
- Where
- 57 sites in United States, Australia and 11 more
- Volunteers
- 134 people
- Sponsor
- Harmony Biosciences Management, Inc.
Attention Deficit Hyperactivity Disorder
Intervention for Teens With ADHD and Substance Use
Individuals with ADHD are at markedly high risk for increased substance use and Substance Use Disorder (SUD). Given the strong evidence for the negative trajectory of individuals with co-occurring ADHD and substance use…
- Trial name
- NCT02502799
- Testing
- Brief Early Intervention, Parent Training with Adolescent Cognitive Behavioral Therapy, Methylphenidate
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Florida International University
Internet-Delivered Cognitive Behavioural Therapy, Depression
Optimizing a Wellbeing Program for Care-partners of Those With SCI
Spinal cord injuries (SCI) have a devastating effect not only on individuals incurring the life changing event, but also on those who are involved in their care.
- Conditions
- Internet-Delivered Cognitive Behavioural Therapy, Depression, Anxiety, Spinal Cord Injuries
- Trial name
- NCT06318832
- Testing
- ICBT
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Pediatric Onset Multiple Sclerosis, ADHD Predominantly Inattentive Type
Cognitive Impairment in Pediatric Onset Multiple Sclerosis
Computer-assisted rehabilitation of attention deficits in pediatric Multiple Sclerosis and ADHD patients recruited during the study "Cognitive impairment in Pediatric Onset Multiple Sclerosis: research of biomarkers predictive of…
- Trial name
- NCT03190902
- Testing
- Attention Processing Training program (APT), nonspecific computer training (n-ST)
- Volunteers
- 36 people
- Sponsor
- Pietro Iaffaldano
Anxiety, Depressive Symptoms
StriveWeekly: Self-Guided Online Intervention for Anxiety, Depression, and Stress in University Students
This study was a randomized controlled trial of an original online mental health promotion program. This study aimed to: 1) establish program effectiveness by examining symptom change between conditions and 2) examine predictors…
- Conditions
- Anxiety, Depressive Symptoms, Stress, Psychological
- Trial name
- NCT04361045
- Testing
- StriveWeekly
- Where
- United States
- Volunteers
- 1,631 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Bipolar Depression
Multiple Treatment Study Using Low Field Magnetic Stimulation for Bipolar Depression
Objectives: To demonstrate the duration of the antidepressant effect of Low Field Magnetic Stimulation (LFMS)in subjects with bipolar depression.
- Trial name
- LFMS (NCT01929681)
- Testing
- Low Field Magnetic Stimulation
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Mclean Hospital
Autism, Autism Spectrum Disorder
Comparing Imitation and Stereotyped Behaviors in Autistic Children: Robots vs. Human Operators
Virtual QT is a social robot designed to interact with humans in social and educational contexts. Equipped with visual and vocal interfaces, the robot can recognize and respond to various human inputs, providing emotional support…
- Trial name
- NCT06144528
- Testing
- QT robot
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Tobacco Use Disorder, Tobacco Smoking
Brain Imaging in Tobacco Smokers During a Quit Attempt
The proposed study will help fill gaps in existing research by determining if nicotine-dependent cigarette smokers show changes in α7 nicotinic acetylcholine receptor (nAChR) availability when compared to matched historical…
- Trial name
- NCT04055467
- Testing
- [F18]-ASEM (3-(1,4-diazabicyclo[3.2.2]nonan-4-yl)-6-[18F]fluorodibenzo[b,d]thiophene 5,5-dioxide), Contingency Management
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Attention Deficit Hyperactivity Disorder
Brain-Computer Interface (BCI) Based Intervention for Attention Deficit Hyperactivity Disorder (ADHD)
This study aims to examine the efficacy of a brain-computer interface system for the treatment of inattentive symptoms of Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- NCT01344044
- Testing
- BCI
- Where
- Singapore
- Volunteers
- 192 people
- Sponsor
- National Healthcare Group, Singapore
Postpartum Depression, Emotional Regulation
Prenatal Affective Cognitive Training to Reduce the Risk of Postpartum Depression (PACT)
Many pregnant women face the risk of experiencing depression after giving birth, especially if they've previously dealt with depression.
- Conditions
- Postpartum Depression, Emotional Regulation, Cognitive Function 1, Social, Pregnancy Related
- Trial name
- PACT (NCT06046456)
- Testing
- Prenatal Affective CogntiiveTraining
- Where
- Denmark
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Insomnia, Quality of Life
Auricular Acupuncture and Cognitive Behavioral Therapy Treatment for Insomnia
"Auricular acupuncture and cognitive behavioral therapy in the context of insomnia and low dose dependence of benzodiazepine-like drugs and other sleep medicine with addiction risk" INTRODUCTION: Insomnia is a common health…
- Trial name
- NADA (NCT01765959)
- Testing
- Auricular acupuncture (AA), cognitive behavioral therapy (CBT)
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uppsala University
ADHD
Parents as Friendship Coaches for Children With ADHD
Many children with Attention-Deficit/Hyperactivity Disorder (ADHD) have problems with making and keeping friends. The current study compared the efficacy of two 10-week behavioral interventions for improving the friendships of…
- Trial name
- NCT04086979
- Testing
- Parental Friendship Coaching, Coping with ADHD through Relationships and Education
- Volunteers
- 172 people
- Sponsor
- University of British Columbia
Fibromyalgia, Social Media Addiction
Fibromyalgia and the Act of Scrolling Through Social Media.
In recent years, the widespread use of social media and digital platforms has led to the emergence of behavioural patterns such as doomscrolling, which involves the compulsive consumption of negative or distressing online…
- Trial name
- NCT07092462
- Where
- Turkey (Türkiye)
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Uşak University
Alcohol Drinking, Binge Drinking
Alcohol, Behavior, and Brain Imaging
To evaluate the relationship of extraversion to both the acute subjective and behavioral effects of alcohol, and the neural reactivity to the anticipation of reward.
- Conditions
- Alcohol Drinking, Binge Drinking, Drinking Behavior, Substance-Related Disorders
- Trial name
- (DARC) (NCT03930446)
- Testing
- Ethanol
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Chicago
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