Clinical trials: Mental and Behavioral Disorders
Bipolar Disorder, Bipolar Depression
Safety Study of Ziprasidone (Geodon) for the Depressive Mixed State
Mixed states in bipolar disorder have long been recognized. Over a century ago, it was argued that mixed states were the most common episodes in manic-depressive illness.
- Conditions
- Bipolar Disorder, Bipolar Depression, Depression
- Trial name
- NCT00490542
- Testing
- ziprasidone (Geodon)
- Where
- 4 sites in United States
- Volunteers
- 73 people
- Sponsor
- Tufts Medical Center
Mild Cognitive Impairment in Middle-aged Adults
Deafness and Cognition in Middle-aged Adults
A mild cognitive impairment was observed in 50% of cochlear implant candidates aged 65 years and over, compared to 5-19% in general population. No studies analysed cognition in patients younger than 65 years.
- Trial name
- SURDICOG (NCT05149742)
- Testing
- Cognitive and audiometry evaluation
- Where
- France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
ADD, ADHD
Neurocognitive and Neurobiological Improvement in ADHD Children by Modification of Dietary Protein
Multicenter, Prospective, randomized, comparative and controlled study about the beneficial effects in behavior and brain connectivity of different dietary patterns in 100 children with ADHD between 7 and 12 years, followed up…
- Trial name
- BrainProtein (NCT01856686)
- Testing
- BP22042013, Low carbohydrate diet
- Where
- United Kingdom
- Volunteers
- 64 people
- Sponsor
- Spanish Foundation for Neurometrics Development
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Depression, Anxiety
Research on Risk Factors and Interventions of Polycystic Ovary Syndrome Complicated With Depression and Anxiety
The current study intends to establish a prediction method and evaluation system for polycystic ovary syndrome (PCOS) complicated with affective disorder, such as depression and anxiety, through the epidemiological investigation.
- Trial name
- PCOS (NCT04984070)
- Testing
- Oral Contraceptives, Combined, Metformin Pill, lifestyle intervention
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fudan University
Attention Deficit Hyperactivity Disorder (ADHD)
Effects of Structured Skills Training Group in Treatment of ADHD in Adults
This study aims to examine if structured skills training group therapy for ADHD in adults has beneficial effects superior to 'treatment as usual' including medication in a controlled outpatient setting on clinically relevant…
- Trial name
- NCT02685254
- Testing
- Structural skills training group, Treatment as usual
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- University of Oslo
Attention Deficit Disorder, Sleep Initiation and Maintenance Disorders
Better Sleep in Psychiatric Care - ADHD Pilot Study
Comorbidities, including sleep problems, are common in adult Attention Deficit Hyperactivity Disorder (ADHD). Treatment of choice for insomnia is cognitive behavioral therapy (CBT-i), but evidence is lacking for CBT-i in patients…
- Conditions
- Attention Deficit Disorder, Sleep Initiation and Maintenance Disorders, Sleep Wake Disorders
- Trial name
- BeSiP-ADHD (NCT03852966)
- Testing
- CBT-i/ADHD
- Where
- Sweden
- Volunteers
- 19 people
- Sponsor
- Karolinska Institutet
Yoga, ADHD
Investigation of the Effect of Yoga on Balance, Reaction Time and Agility in Children With ADHD
Purpose: To determine the effect of 8-week kids yoga training on balance, reaction time and agility on children diagnosed with attention deficit hyperactivity disorder (ADHD). Method: A randomized controlled trial.
- Conditions
- Yoga, ADHD, Balance, Children, Only
- Trial name
- NCT05742451
- Testing
- kids yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 17 people
- Sponsor
- Ankara Medipol University
Behavior Problem
Teachers and Parents as Partners During Middle School
There are two aims of this study (a) to examine the effect of Teachers and Parents as Partners on student, parent, and teacher outcomes in middle school and (b) identify barriers and facilitators to implementing Teachers and…
- Trial name
- NCT03298724
- Testing
- Teachers and Parents as Partners
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Attention Deficit Hyperactivity Disorder
Effects of Aerobic Exercise Intervention in Adolescents With Attention-deficit/Hyperactivity Disorder (ADHD)
The goal of this clinical trial is to investigate the neurophysiological foundation of the impact of the acute effects of controlled aerobic exercise intensity in adolescents with ADHD, its involvement in cognitive processes, and…
- Trial name
- NCT06129396
- Testing
- Aerobic exercise, Video-watching
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taiwan University Hospital
MDMA Discontinuation Syndrome
Study of the Effects of MDMA/Ecstasy on Water Regulation, Sleep, and Cognition.
The purpose of this study is to measure the effects of MDMA on sleep, mood, thinking, and how your body retains water. The researchers are interested in the effects that occur a few hours after taking MDMA as well as effects…
- Trial name
- 2C (NCT01053403)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- California Pacific Medical Center Research Institute
Distress, Emotional, Emotional Dysfunction
Brief Interventions for Coping with Distress
This study is being done to compare the effectiveness of three different skills trainings to cope with distress. These three trainings are: 1) an attention skills training, 2) an attention and reflective thought skills training…
- Conditions
- Distress, Emotional, Emotional Dysfunction, Anxiety, Depression
- Trial name
- NCT05779761
- Testing
- Online, Self-Directed Attention Skills Training with Coaching Support, Online, Self-Directed Attention & Reflective Thought Skills Training with Coaching Support, Online, Self-Directed Health & Wellness Education Training with Coaching Support
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Teachers College, Columbia University
Type 2 Diabetes, Lifestyle-related Condition
High Intensity Interval Training and Insulin Sensitivity in Type 2 Diabetes
A recognized driver for cardiovascular complications of type 2 diabetes mellitus (T2DM) is impaired plasma glucose homeostasis as consequence of skeletal muscle insulin resistance.
- Conditions
- Type 2 Diabetes, Lifestyle-related Condition, Insulin Sensitivity/Resistance
- Trial name
- T2D-HIIT (NCT06688461)
- Testing
- Experimental group: Exercise training
- Where
- Chile
- Volunteers
- 36 people
- Sponsor
- Finis Terrae University
Depressive Disorder
An Eight-week Study Evaluating the Efficacy of a 100mg Dose of Saredutant Once Daily, in Elderly Patients With Major Depressive Disorder
The purpose of the study is to evaluate the efficacy of saredutant in the treatment of Major Depressive Disorder in elderly patients.To evaluate the tolerability, safety and efficacy on disability and quality of life in patients…
- Trial name
- NCT00415142
- Testing
- saredutant (SR48968), escitalopram
- Where
- 8 sites in United States, Croatia and 6 more
- Volunteers
- 393 people
- Sponsor
- Sanofi
Depression, Anxiety Disorders
Tailored Internet-delivered Cognitive Behaviour Therapy for Symptoms of Depression and Comorbid Problems
The overall aim of this study is to develop and test a tailored Internet-delivered psychological treatment for patients with mild to moderate major depression and comorbid anxiety symptoms and compare its efficacy to a…
- Trial name
- TAYLOR1 (NCT01181583)
- Testing
- Tailored Internet-delivered CBT, Non-tailored Internet-delivered CBT, Online discussion group
- Where
- Sweden
- Volunteers
- 121 people
- Sponsor
- Linkoeping University
Mental Health Wellness 1, Addiction
Finding Wellness in the Pandemic
There is an immediate need for population-level intervention research to address the impacts of the coronavirus disease 2019 (COVID-19) pandemic and its containment measures on mental health and substance use (MHSU).
- Conditions
- Mental Health Wellness 1, Addiction, Stress, Psychological, Covid19
- Trial name
- NCT04615741
- Testing
- Trauma Informed Yoga, Trauma Informed Psychotherapy
- Where
- Canada
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- University of Lethbridge
Trichotillomania
Trial of Aripiprazole in Trichotillomania
No medication has been reliably shown to benefit those suffering from trichotillomania (compulsive hair pulling). The current study proposes to evaluate the effectiveness of the medication aripiprazole for treatment of…
- Trial name
- NCT00947154
- Testing
- aripiprazole
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stanford University
Smoking Cessation, Acceptability of Health Care
Re-Connect Application for Smoking Cessation
This series of studies will explore the acceptability, feasibility, and preliminary efficacy of making access to smartphone applications contingent on objective evidence of smoking abstinence.
- Conditions
- Smoking Cessation, Acceptability of Health Care, Nicotine Dependence, Cigarettes
- Trial name
- NCT05224154
- Testing
- Abstinent Contingent (AC) Re-Connect
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Rowan University
Depression, Stress
Effects of Landscapes on the Brain
There is an established consensus between researchers that the contact with natural environments has beneficial influence on mental health and well-being of people exposed to them.
- Conditions
- Depression, Stress, Anxiety Disorders
- Trial name
- NCT04210856
- Testing
- Contemplative landscape exposure
- Where
- Singapore
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Attention Deficit Hyperactivity Disorder, Substance Use Disorder
Efficacy of Atomoxetine for ADHD in Adolescents and Young Adults With SUD
The primary objective of the study is to investigate the efficacy of Atomoxetine (ATMX) in the treatments of adolescent and young adult Attention Deficit Hyperactivity Disorder (ADHD) with comorbid Substance Use Disorder (SUD).
- Trial name
- NCT01207622
- Testing
- Atomoxetine
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Suicide, Mental Health Disorder
Optimizing a Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents
Despite efforts to prevent suicide, US rates are climbing, and suicide is the second leading cause of death amongst youth. Digital tools, especially personal smartphones, are promising avenues to address these issues and can be…
- Conditions
- Suicide, Mental Health Disorder, Anhedonia
- Trial name
- NCT06665620
- Testing
- ViraBrite nudges
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Ksana Health
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