Clinical trials: Mental and Behavioral Disorders
Disruptive Behavior Disorder, Emotional Disorder
Matching Assessment and Treatment for Children With Disruptive Behaviour and Their Parents
This study will develop and test whether personalized profiles of children with Disruptive Behaviour Disorder (DBD) and their parents based on important psychological, emotional, and neuropsychological indicators predict their…
- Conditions
- Disruptive Behavior Disorder, Emotional Disorder, Behavioural Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- MATCH-DB (NCT06373484)
- Testing
- Behavioral Parent Training
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Centre for Addiction and Mental Health
Depression, Pregnancy
Depression Prevention Program for American Indian Adolescents During and After Pregnancy
This study will determine the effectiveness of the "Living in Harmony" depression prevention program in preventing depressive symptoms among pregnant American Indian adolescents during pregnancy and after giving birth.
- Trial name
- NCT00183547
- Testing
- "Living in Harmony" depression prevention program, Depression-prevention education and support
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Marijuana Dependence
Maximizing the Efficacy of Cognitive Behavior Therapy and Contingency Management
Cognitive-behavioral coping skills therapy (CBT) is a widely used and recognized treatment that has been empirically validated for a range of substance use disorders, often with emergent effects and continuing improvement even…
- Trial name
- NCT00350649
- Testing
- Standard CBT, CBT+CM/adherence, CM/abstinence
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- Yale University
Depressive Disorder
A Randomised, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of Orvepitant in Subjects With Major Depressive Disorder
This is a 6-week, randomised, multicenter, double-blind, placebo controlled, fixed dose parallel group study to assess the efficacy and safety of orvepitant (30 and 60 mg/day) versus placebo in subjects with a diagnosis of a…
- Trial name
- Orvepitant MDD (NCT00880048)
- Testing
- orvepitant
- Where
- 32 sites in United States, Canada
- Volunteers
- 343 people
- Sponsor
- GlaxoSmithKline
Anxiety Acute, Stress
Drumming Groups for Parents of Autistic Children
This project aims to encourage a sense of belonging, community, and emotional support for parents of autistic children through a group drumming (music therapy) intervention.
- Conditions
- Anxiety Acute, Stress, Depression and Quality of Life, Stress in Parents of Autistic Children
- Trial name
- DG_PAC (NCT07375043)
- Testing
- Group Drumming
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Overweight, Obesity
Increasing the Effectiveness of the Diabetes Prevention Program
The Diabetes Prevention Program (DPP) is highly effective in promoting weight loss in overweight and obese individuals (e.g., 7% average loss of body weight), and thereby reducing the risk of developing weight-related health…
- Trial name
- NCT02008435
- Testing
- Enriched GLB, Standard GLB
- Where
- Canada
- Volunteers
- 172 people
- Sponsor
- McGill University
ADHD
RCT of EF Family Training for P ADHD
To explore the effect of executive function family training for preschool children with ADHD, providing early social psychological intervention for aiming the core impairments of ADHD.
- Trial name
- NCT04454008
- Testing
- executive function family training, treat as usual
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Depressive Disorder, Depression
Mindfulness Based Emotion Regulation Therapy in the Treatment of Depressive Rumination
In this study the investigators are examining the neuronal processes of a mindfulness based emotion regulation training for reducing depressive rumination.
- Conditions
- Depressive Disorder, Depression, Rumination
- Trial name
- NCT04560192
- Testing
- Mindfulness based Emotion regulation therapy (MBERT) - Treatment as usual (TAU), Treatment as usual (TAU) - Mindfulness based Emotion regulation therapy (MBERT)
- Where
- Germany
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Depressive Symptoms
Automated and Personalized Cognitive Behavioral Therapy
This study is designed to evaluate a novel online tool to deliver computerized Cognitive Behavioral Therapy (CBT). Participants will be randomized into three groups: experimental, active control, and waitlist.
- Trial name
- NCT03445598
- Testing
- Interactive and personalized CCBT, Feature-limited CCBT, Waitlist control
- Where
- India
- Volunteers
- 600 people
- Sponsor
- Indian Institute of Technology Kanpur
Tobacco Dependence
Study to Determine if a New Nicotine Replacement Therapy Can Safely Help Smokers to Quit Smoking
This study is to see if a new nicotine replacement therapy safely helps people to quit smoking if it is used the way it would be if it were sold at the pharmacy and used at home.
- Trial name
- NCT01296698
- Testing
- Nicotine
- Where
- 19 sites in United States
- Volunteers
- 257 people
- Sponsor
- McNeil Consumer Healthcare Division of McNEIL-PPC, Inc.
Depressive Symptoms, Anxiety
Expressive Writing on Minority Stressors Among Sexual Minority Veterans
Sexual minority stressors (e.g., sexual minority identity-based discrimination) contribute to greater risk for and severity of depression, anxiety, substance use disorders and suicide among sexual minority Veterans.
- Trial name
- EWMS (NCT05897021)
- Testing
- Expressive Writing on Minority Stressors, Neutral Writing
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- VA Office of Research and Development
Colorectal Cancer
This Trial Corresponds to the Manuscript Titled: Effects of Tai Chi on Balance and Sleep Quality in Colorectal Cancer Patients Undergoing Chemotherapy
Colorectal cancer patients receiving adjuvant chemotherapy may experience reduced physical fitness, fatigue, emotional distress, sleep problems, and impaired quality of life.
- Trial name
- NCT07833358
- Testing
- Tai Chi Exercise Program
- Where
- 2 sites in Taiwan
- Volunteers
- 60 people
- Sponsor
- Ya-Fen Fan
Insomnia
Feasibility of Internet Group CBT-I for Gyn Oncology Patients
The goal of this study is to evaluate the feasibility and acceptability of delivering cognitive behavioral therapy for insomnia (CBT-I) to gynecologic cancer patients in an internet-based small-group setting.
- Trial name
- NCT06060158
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of California, Davis
Mental Disorders, Severe
Evaluation of an Animal Assisted Therapy Program in People With Mental Illness, and Promotion of Positive Mental Health
Scientific literature reports that focusing interventions on people with mental health problems, from the threshold of Positive Mental Health, is effective and allows the person to promote positive mental health behaviors.
- Trial name
- NCT05004298
- Testing
- Animal Assited therapy
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Drug Use Disorders, Illicit Drug Use
Addressing Barriers to Care for Substance Use Disorder Pilot Study
The Addressing Barriers to Care for Substance Use Disorder Pilot (ABC-SUD Pilot) was a randomized pilot study that preceded a larger trial.
- Conditions
- Drug Use Disorders, Illicit Drug Use, Alcohol-Related Disorders
- Trial name
- ABCSUD Pilot (NCT06317987)
- Testing
- Care Navigation
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Kaiser Permanente
Health College Students
Effects of VR Tai Chi Intervention on Physical Fitness, Anxiety, Depression and Stress Among College Students in Henan, China
Research indicates a substantial increase in the rates of anxiety, depression and stress among college students (Roy, Biswas, \& Sharma, 2025).
- Trial name
- NCT07854821
- Testing
- Virtual Reality-Assisted Tai Chi Training
- Where
- China
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Xin Liu
Tourette's Disorder, Persistent (Chronic) Motor or Vocal Tic Disorder
TicHelper: A Computerized Comprehensive Behavioral Intervention for Tics (CBIT)
Tic Disorders (including Tourette Disorder) are relatively common in school-age children and for some children can lead to significant psychosocial and physical impairment and diminished quality of life.
- Trial name
- NCT02413216
- Testing
- TicHelper, Internet Based Resources
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- University of Utah
Prostate Cancer, Urologic Cancer
The Man Van Project
National Health Service (NHS) England has commissioned The Royal Marsden Hospital NHS Foundation Trust to run a novel mobile clinical outreach service called 'Man Van' with the aim of enabling male patients' easy access to care…
- Conditions
- Prostate Cancer, Urologic Cancer, Urologic Diseases, Bladder Cancer
- Trial name
- MV (NCT06357416)
- Testing
- MV-POCT Sub-study, Main Man Van Group Sub-study (MV-Eco), MV-QualQ Sub-study
- Where
- United Kingdom
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Bone Diseases, Metabolic, Depression, Involutional
Use of Bone Biopsy to Better Understand the Causes of Decreased Bone Mineral Density in Depression
In this study researchers would like to learn more about the low levels of bone mineral density seen in approximately half of women in their forties diagnosed as currently having or previously had depression.
- Conditions
- Bone Diseases, Metabolic, Depression, Involutional, Osteoporosis
- Trial name
- NCT00001916
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- National Institute of Mental Health (NIMH)
Weight Regain After Bariatric Surgery and Food Addiction, Eating Behavior
Intuitive Eating Intervention After Bariatric Surgery
This study evaluated the validity and reliability of the Turkish version of the Intuitive Eating Scale-2 (IES-2) in individuals who had undergone bariatric surgery and examined the effects of a 6-week online intuitive eating…
- Conditions
- Weight Regain After Bariatric Surgery and Food Addiction, Eating Behavior, Body Image
- Trial name
- NCT07859449
- Testing
- Intuitive Eating Intervention, Standard Nutritional Counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Acibadem University
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