Clinical trials: Mental and Behavioral Disorders
Mental Fatigue, Fatigue
Effect of Ginko and Cistanche Against Fatigue Symptoms
To evaluate the efficacy of Nutrilite® ginkgo biloba cistanche tablets in relieving the symptoms of chronic fatigue syndrome(CFS), the investigators randomly recruit189 subjects with CFS, aged 35-60 yrs.
- Conditions
- Mental Fatigue, Fatigue, Chronic Fatigue Syndrome
- Trial name
- GkoCist (NCT02807649)
- Testing
- Experimental: Nutrilite® Low dose, Experimental: Nutrilite® High dose
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Access Business Group
Psychosis, Dementia
A Study of MP-101 in Dementia-Related Psychosis and/or Agitation and Aggression
A ten-week study to assess MP-101 in Dementia-Related Psychosis and/or Agitation and Aggression
- Conditions
- Psychosis, Dementia, Aggression, Agitation
- Trial name
- NCT03044249
- Testing
- MP-101
- Where
- 20 sites in United States, Canada
- Volunteers
- 81 people
- Sponsor
- Mediti Pharma Inc.
Anxiety, Paediatric
Comparison of Efficacy of Little Lovely Dentist, Dental Song and Tell-show-do Techniques in Alleviating Dental Anxiety in Paediatric Patients
To evaluate the efficacy of different techniques for the reduction of dental anxiety in pediatric patients. Generally, anxiety amongst paediatric patients is higher as compared to adult patients.
- Conditions
- Anxiety, Paediatric, Dental Anxiety, Behaviour
- Trial name
- NCT04833478
- Testing
- Anxiety
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine
Suicide, Mental Disorder
Systems Aligning for Equity (SAFE) Spaces
The goal of this 2-arm cluster randomized clinical trial is to test whether an evidence-based staff training and coaching model specifically designed as a response to legal system-involved youths' and frontline staff's mental…
- Conditions
- Suicide, Mental Disorder, Mental Health, Burnout, Professional
- Trial name
- SAFE Spaces (NCT05658068)
- Testing
- SAFE Spaces training and coaching
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- New York University
Sleep Quality
Improving Sleep in Veterans and Their CGs
This study addresses the neglected topic of sleep disturbance in older caregiving dyads-a topic that has important implications for the safety, health, functioning and quality of life of older Veterans living at home and being…
- Trial name
- SLEEP-E Dyads (NCT02057068)
- Testing
- SLEEP-E Dyads Intervention
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Attention Deficit Hyperactivity Disorder (ADHD)
The MEASURE Study - A Phase 3 Study of MDX 1400 mg Daily Compared With Placebo in Adults With ADHD
This study is a multi-center, randomized, double-blind, placebo-controlled, phase 3 study of MDX (1400 mg daily) for 10 weeks compared with placebo in adults with ADHD.
- Trial name
- NCT02477748
- Testing
- MDX
- Where
- 38 sites in United States, Israel
- Volunteers
- 283 people, healthy volunteers welcome
- Sponsor
- Alcobra Ltd.
Fragile X Syndrome, Behavior
An Investigation of Psilocybin on Behavioural and Cognitive Symptoms of Adults With Fragile X Syndrome
Diverse symptomatology makes Fragile X Syndrome (FXS) difficult to treat, and currently there are no approved prevention or treatment methods for FXS.
- Conditions
- Fragile X Syndrome, Behavior, Cognitive Dysfunction
- Trial name
- NCT05832255
- Testing
- Psilocybin, 1.5 mg
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Nova Mentis Life Science Corp
Mild Cognitive Impairment, Cognitive Decline
Exercise in Adults With Mild Memory Problems
This study evaluates the effects of physical exercise on cognition, functional status, brain atrophy and blood flow, and cerebrospinal fluid biomarkers of Alzheimer's disease in adults with a mild memory impairment.
- Conditions
- Mild Cognitive Impairment, Cognitive Decline, Memory Impairment
- Trial name
- EXERT (NCT02814526)
- Testing
- Aerobic exercise, Stretching/balance/range of motion exercise
- Where
- 14 sites in United States
- Volunteers
- 296 people
- Sponsor
- Alzheimer's Disease Cooperative Study (ADCS)
Sleep Initiation and Maintenance Disorders
Mechanisms of Change in Cognitive Behavioral Therapy for Insomnia (CBTi)
The purpose of this study is to investigate the mechanisms of change in Cognitive Behavioral Therapy for insomnia (CBTi) in a sample of adults aged 50-65.
- Trial name
- CBTi (NCT05226585)
- Testing
- In-Person Cognitive Behavioral Therapy for Insomnia, Telehealth Cognitive Behavioral Therapy for Insomnia, Internet Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- University of Arizona
Adolescent Behavior, Borderline Personality Disorder
Connectivity and Social Cognition in Adolescent Girls With Borderline Personality Disorder, a Pilot Study
The disruption of social cognition associated with borderline personality disorder (BPD), and more specifically categorization of facial emotions, remains largely under-studied, despite the high frequency of this pathology in the…
- Trial name
- EEG-NIRS (NCT03139825)
- Testing
- Exploring the feasibility of learning during cognitive tasks (EEG-NIRS)
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire, Amiens
COPD (Chronic Obstructive Pulmonary Disease)
Respiratory Rehabilitation and Sleep Quality in COPD Patients
COPD affects 5 to 8% of the population in France. The disease consists of inflammation of the large and small airways causing permanent obstruction of the airways and symptoms such as dyspnea, cough and sputum that worsens over…
- Trial name
- REARSOM/BPCO (NCT06677268)
- Testing
- Rehabilitation
- Where
- 4 sites in France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Rouen
Major Depressive Episode
Cohort of Patients Suffering From Major Depressive Episode With Evaluation of Sleep, Circadian Rhythms and Psychiatric Disorders
Despite international efforts to identify biomarkers of depression, none has been transferred to clinical practice, neither for diagnosis, evolution, nor therapeutic response.
- Trial name
- SoPsy-SoSad (NCT05866991)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Depression, Sleep
The Acute Effect of Aerobic Exercise on Sleep in Patients With Depression
The aim of this trial is to investigate the effects of a single bout of aerobic exercise on sleep in patients with depression.
- Conditions
- Depression, Sleep, Sleep Disorder, Sleep Disturbance
- Trial name
- EASED (NCT03673397)
- Testing
- Aerobic exercise, bicycle ergometer
- Where
- Switzerland
- Volunteers
- 92 people
- Sponsor
- Oberwaid AG
Depression, Anxiety
Feasibility and Acceptability of W-GenZD vs CBT-light Teletherapy for Adolescents Seeking Mental Health Services
The primary aim of this study is to determine the feasibility and acceptability of the W-GenZD mobile application among a group of adolescents and who have screened and triaged into low-intensity treatment within the Children's…
- Trial name
- NCT05372913
- Testing
- Woebot for Adolescents (W-GenZD) Mobile Application, CBT-Lite Teletherapy Group
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Woebot Health
Alcohol Dependence
Efficacy of Repetitive Transcranial Magnetic Stimulation and Cognitive Behavioral Therapy on Alcohol Dependence
Alcohol dependence is one of most common substance dependence, which brings great burden on health worldwide. Alcohol dependence may lead to many serious diseases or consequences including cancer, cardiovascular diseases and…
- Trial name
- TAD (NCT03910686)
- Testing
- Transcranial magnetic stimulation and cognitive behavioral therapy
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Oral Lichen Planus, Thyroid Disease
Association Between Oral Lichen Planus and Thyroid Disease
The goal of this observational study is to determine the prevalence of thyroid disease in adults with oral lichen planus (OLP) treated at the Dental Hospital of the University of Barcelona (HOUB), and to evaluate the association…
- Trial name
- NCT06550154
- Testing
- Data collection
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Asthma
The Relationship Between Kinesiophobia, Physical Activity Level and Quality of Life in Asthma Patients
Asthma is a heterogeneous disease characterized by chronic airway inflammation characterized by time-varying respiratory symptoms such as wheezing, shortness of breath, chest tightness and cough, with limitation of expiratory…
- Trial name
- NCT04181905
- Testing
- Questionnaire
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Marmara University
Substance-Related Disorders
Women's Treatment for Trauma and Substance Use Disorders - 1
The purpose of this study is to compare the effectiveness of adding Seeking Safety to standard substance abuse treatment to adding a control condition: Women's Health Education to standard substance abuse treatment.
- Trial name
- NCT00078156
- Testing
- Behavior Therapy
- Where
- 7 sites in United States
- Volunteers
- 409 people
- Sponsor
- New York State Psychiatric Institute
Attention Deficit Disorder With Hyperactivity
An Efficacy and Safety Study of Osmotic Release Oral System (OROS) Methylphenidate in Participants With Attention Deficit Hyperactivity Disorder (ADHD)
The purpose of this study is to evaluate the safety and efficacy of Osmotic Release Oral System (OROS) methylphenidate in participants with Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- NCT01012622
- Testing
- Osmotic Release Oral System (OROS) Methylphenidate Hydrochloride
- Volunteers
- 142 people
- Sponsor
- Janssen Korea, Ltd., Korea
Hypoactive Sexual Desire Disorder
Waitlist Controlled Comparison of Cognitive-behavioral vs. Mindfulness-based Online-treatments for Women With Low Sexual Desire
Problems with sexual function are common and distressing. The most frequent sexual difficulty in women is a lack of sexual desire with a prevalence of 20-30%.
- Trial name
- MiSELF (NCT03780751)
- Testing
- Cognitive-behavioral treatment, Mindfulness-based treatment
- Where
- Germany
- Volunteers
- 266 people
- Sponsor
- Ruhr University of Bochum
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