Clinical trials: Metabolic Cardiovascular Syndrome
Gestational Diabetes Mellitus in Pregnancy, Vitamin D Deficiency
Effects of Vitamin D Supplementation on Glucose Metabolism in Women With Former Gestational Diabetes Mellitus
Gestational Diabetes Mellitus (GDM) and vitamin D deficiency are related to insulin resistance and impaired beta-cell function, with heightened risk for future development of diabetes.
- Trial name
- NCT01992133
- Testing
- Vitamin D3
- Where
- Malaysia
- Volunteers
- 26 people
- Sponsor
- RCSI & UCD Malaysia Campus
Metabolic Syndrome
Metabolic Actions of Omega-3 Fatty Acids
The metabolic syndrome raises the risk of heart disease and is currently at epidemic proportions in the U.S. It consists of 3 of the following components: central obesity, high triglycerides, low HDL, abnormal blood pressure and…
- Trial name
- NCT01896414
- Testing
- EPA (marine fatty acids)
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Metabolic Syndrome, Abdominal Obesity
Copenhagen Obesity Risk Assessment Study
The aim of the present study is to assess the effect of a high intake of industrially produced trans fatty acids for 16 weeks on abdominal obesity and risk markers of type 2 diabetes and heart disease in healthy, moderately…
- Conditions
- Metabolic Syndrome, Abdominal Obesity, Heart Disease, Type 2 Diabetes
- Trial name
- COBRA (NCT00655902)
- Testing
- Trans fat (soy bean oil), Control fat (sunflower oil)
- Where
- Denmark
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Motor Activity, Body Weight
Effects of Aerobic Exercise Detraining
The proposed study seeks to better understand the role of body weight, energy expenditure, and energy intake as mechanisms of body weight gain during detraining following aerobic exercise.
- Conditions
- Motor Activity, Body Weight, Obesity
- Trial name
- E-Mechanic_Fol (NCT02158130)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Metabolic Syndrome, Hypertension
Effect of Two Doses of Olmesartan Medoxomil and Amlodipine on Vascular Markers in Hypertensive Patients With Metabolic Syndrome
The purpose of this study is to study the effect of two doses of olmesartan medoxomil and amlodipine on vascular markers in hypertensive patients with metabolic syndrome.
- Trial name
- VAMOS (NCT00891267)
- Testing
- Olmesartan medoxomil tablets low dose, Olmesartan medoxomil tablets high dose, Amlodipine
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company
Diabetic Ketoacidosis, Heart Disease, Ischemic
Effectiveness of Music Intervention on Anxiety and Physiological Responses in Critical Ill Patient
Music intervention is a non-pharmacological and effective intervention that can alleviate anxiety and agitation in patients undergoing weaning.
- Conditions
- Diabetic Ketoacidosis, Heart Disease, Ischemic, Stroke, GastroIntestinal Bleeding
- Trial name
- NCT04977011
- Testing
- relaxing music
- Where
- Taiwan
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Min-Sheng General Hospital
Metabolic Syndrome, Complementary Therapies
The Effects of Fenugreek Extract (Fenobet) on Metabolic Syndrome
The current study is a three-blind, randomized clinical trial study that will be conducted on 60 people with metabolic syndrome. The eligible participants were allocated randomly to one of the two study groups (Fenobet, Placebo).
- Conditions
- Metabolic Syndrome, Complementary Therapies, Diabetes Mellitus, Type 2
- Trial name
- Fenobet (NCT06114134)
- Testing
- Fenobet
- Volunteers
- 60 people
- Sponsor
- Tehran University of Medical Sciences
Schizophrenia and Disorders With Psychotic Features
One-Year Trial Of Oral Ziprasidone In Patients With Metabolic Syndrome
The purpose of this study is to explore the impact of ziprasidone on the distribution of metabolic syndrome risk factors in a population of patients presenting with glucose intolerance, dyslipidemia and/or elevated waist…
- Trial name
- NCT00748566
- Testing
- Ziprasidone HCL (oral)
- Where
- 32 sites in Canada
- Volunteers
- 172 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Hyperuricemia, Healthy
The Relationship Among, Serum Uric Acid, Left Ventricular Hypertrophy and Metabolic Syndrome
Hyperuricemia is associated with the prevalence of metabolic syndrome and cardiovascular risks in diverse of the population. Whether the dose-response effects on the prevalence of metabolic syndrome and cardiometabolic risks is…
- Trial name
- NCT03473951
- Testing
- Hyperuricemia
- Where
- Taiwan
- Volunteers
- 18,000 people, healthy volunteers welcome
- Sponsor
- National Defense Medical Center, Taiwan
Obesity
Prevention of Obesity in Women Via Estradiol Regulation
The purpose of this study is to evaluate potential mechanisms by which estradiol deficiency accelerates fat gain and abdominal fat accumulation in women.
- Trial name
- POWER (NCT00687739)
- Testing
- leuprolide acetate, Estradiol Transdermal, progressive resistance exercise training
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Type 2 Diabetes Mellitus, Chronic Kidney Disease
Extended Release Exenatide Versus Placebo In Diabetic Patients With Type 4 Cardiorenal Syndrome
Among adult individuals with type 2 diabetes mellitus and at risk for heart failure with impaired relaxation of the heart mildly reduced kidney filtration function (Type 4 cardiorenal syndrome) this trial will evaluate the…
- Conditions
- Type 2 Diabetes Mellitus, Chronic Kidney Disease, Left Ventricular Diastolic Dysfunction
- Trial name
- NCT02251431
- Testing
- BYDUREON
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Baylor Research Institute
Achalasia, Esophageal
Metabolic Changes Associated With Weight Gain After Treatment of Achalasia
This goal of the study is to assess the effect of weight gain in patients with achalasia after they are treated. The main question to be answered is if weight gain after achalasia treatment is associated with worsening metabolic…
- Trial name
- NCT07334639
- Where
- 2 sites in Israel
- Volunteers
- 30 people
- Sponsor
- Assaf-Harofeh Medical Center
Cardiovascular Kidney Metabolic Syndrome
Using Secondary Data to Evaluate Sex-based Heterogeneity of GLP-1 Agonists and SGLT2 Inhibitors on Cardiovascular-Kidney-Metabolic Health (CKMH) Outcomes in Real-world Settings (DASH-CKMH)
Complex pathophysiological interactions among obesity, metabolic risk factors, chronic kidney disease (CKD), and the cardiovascular system lead to poor cardiovascular-kidney-metabolic health (CKMH), which is a major determinant…
- Trial name
- DASH-CKMH (NCT07188545)
- Testing
- Intervention, Active Comparator
- Where
- United States
- Volunteers
- 23,280,000 people
- Sponsor
- Ohio State University
Iron Overload, Accelerated Phase Chronic Myelogenous Leukemia
Deferasirox for Treating Patients Who Have Undergone Allogeneic Stem Cell Transplant and Have Iron Overload
RATIONALE: Low dose deferasirox may be safe and effective in treating patients who have undergone hematopoietic stem cell transplant and have iron overload.
- Conditions
- Iron Overload, Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission
- Trial name
- NCT01159067
- Testing
- deferasirox
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- City of Hope Medical Center
Effect of Breastfeeding on Maternal and Child Health Outcomes
Promotion of Breastfeeding Intervention Trial
The overall goal of the PROBIT study is to investigate the influence of a randomized breastfeeding promotion intervention designed to increase the duration and exclusivity of breastfeeding ("the breastfeeding promotion…
- Trial name
- PROBIT (NCT01561612)
- Testing
- Breastfeeding promotion and support
- Where
- Belarus
- Volunteers
- 17,046 people
- Sponsor
- Harvard Pilgrim Health Care
Metabolic Syndrome
Promoting Healthy Habits in Metabolic Syndrome
A randomized controlled trial will be conducted to evaluate the effectiveness of the Habit Design (HD) approach in a corporate health context over the course of one year in subjects with metabolic syndrome.
- Trial name
- NCT04262401
- Testing
- Standard health coaching, Habit-focused health coaching
- Where
- United States
- Volunteers
- 424 people
- Sponsor
- Habit Design
Ataxia Telangiectasia
Ataxia-telangiectasia: Treating Mitochondrial Dysfunction With Nicotinamide Riboside
Study design: Single arm open-label clinical trial in ataxia-telangiectasia to test the effects of nicotinamide riboside on ataxia scales, immune function, and neurofilament light chain.
- Trial name
- ATNAD (NCT06324877)
- Testing
- Nicotinamide riboside
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- The University of Queensland
Insulin Resistance, Obesity
Integrating the Genetic and Metabolic Faces of Obesity
The goal of this study is to determine why some obese individuals develop insulin resistance and others do not. We hypothesize that an impairment in differentiation of fat cells (adipocytes) is responsible for the development of…
- Conditions
- Insulin Resistance, Obesity, Metabolic Syndrome
- Trial name
- NCT00285844
- Testing
- weight loss, thiazolidinedione
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Stanford University
Metabolic Syndrome X
Effect of Dapagliflozin Administration on Metabolic Syndrome, Insulin Sensitivity, and Insulin Secretion
The Metabolic Syndrome is a high prevalence disease worldwide. About a quarter of the adult population suffers the disease. Dapagliflozin is an inhibitor of the sodium-glucose co-transporter SGLT2 in the kidney and is a novel…
- Trial name
- NCT02113241
- Testing
- Dapagliflozin
- Where
- Mexico
- Volunteers
- 24 people
- Sponsor
- University of Guadalajara
Subjects With Abdominal Obesity
Grape and Pomegranate Polyphenols in Postprandial Glucose and Related Parameters
The aim of this is study is to evaluate the acute effect of grape and pomegranate polyphenols in the modulation of markers of metabolic syndrome.
- Trial name
- POME-GRAPE-1 (NCT02710461)
- Testing
- Mixture of grape pomace and pomegranate pomace
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Research Council, Spain