Clinical trials: Metabolic Cardiovascular Syndrome
Congenital Adrenal Hyperplasia, Hypogonadotropic Hypogonadism
Growing up With the Young Endocrine Support System (YESS!)
Transition from paediatric to adult endocrinology is a challenge for adolescents, families and doctors. Up to 25% of young adults with chronic endocrine disorders are lost to follow-up ('drop-out') once the young adult moves out…
- Conditions
- Congenital Adrenal Hyperplasia, Hypogonadotropic Hypogonadism, Growth Hormone Deficiency, Combined Pituitary Hormone Deficiency
- Trial name
- YESS (NCT04252001)
- Testing
- YESS! game, Snake '97, Transition-toolkit
- Where
- 7 sites in Belgium, Netherlands and 2 more
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- dr. Laura C. G. de Graaff-Herder
Bipolar Disorder
BIMET Study: Evolution of Metabolic and Cardiovascular Risks Factors in Patients With Bipolar Disorder
To assess the prevalence of Metabolic Syndrome in Spanish population with Bipolar I or II Disorder. To analyse the clinical progress disease in patients with Bipolar I or II Disorder for 12 months using the assessment of the…
- Trial name
- BIMET (NCT00584961)
- Testing
- non-interventional
- Volunteers
- 553 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Metabolic Syndrome
Conjugated Linoleic Acid / Leucine Versus Metformin on Visceral Fat in Metabolic Syndrome
In Mexico, obesity is a major public health problem. In recent years he has presented a considerable increase in the population.
- Trial name
- NCT02629627
- Testing
- Conjugated linoleic acid/Leucine, Metformin
- Volunteers
- 104 people
- Sponsor
- Centro Universitario de Ciencias de la Salud, Mexico
Postpartum Depression, Postpartum Anxiety
The Mom and Infant Outcomes (MOMI) Study
The investigator's long-term goal is to mitigate pregnancy-related mortality (PRM) risk by systematically delivering scalable integrated clinical and supportive care that is effective for all.
- Conditions
- Postpartum Depression, Postpartum Anxiety, Cardiometabolic Syndrome
- Trial name
- NCT06277661
- Testing
- MOMI PODS, Enhanced Usual Care (EUC)
- Where
- United States
- Volunteers
- 384 people
- Sponsor
- Ohio State University
Metabolic Syndrome, Obesity
Virtual Enhanced Lifestyle for Metabolic Syndrome (ELM) Proof-of-Concept Study
This is a proof-of-concept study of a virtual version of a lifestyle intervention aimed at reducing cardiometabolic risk in patients with the Metabolic Syndrome (MetS).
- Trial name
- NCT04637477
- Testing
- Virtual ELM
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Pediatric Cancer
Adapted Physical Activity for Children Treated With Cancer and Insulin Sensitivity
The main objective of this study is to evaluate the evolution of the sensitivity to insulin, a hormone that acts on sugar in the body, as well as other metabolic, motor and nutritional elements of children with cancer, according…
- Trial name
- APACIS (NCT05383092)
- Testing
- Adapted Physical Activity Strong
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Toulouse
Metabolic Syndrome, Aging
Sustainable Exercise and Nutrition Programs for Managing Metabolic Disorders in Older Women
This study aims to evaluate the impact of sustainable diet and exercise programs on metabolic health and quality of life in older women.
- Conditions
- Metabolic Syndrome, Aging, Sarcopenia, Obesity
- Trial name
- NCT07015307
- Testing
- Sustainable Diet Program, Supervised Physical Exercise Program, Combined Sustainable Diet and Exercise Program
- Where
- Spain
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Alicante
Sex Chromosome Abnormality, Klinefelter Syndrome
Endocrine, Metabolic, Cardiovascular and Immunological Aspects of Sex Chromosome Abnormalities in Relation to Genotype
Observational study of 160 patients with sex-chromosome abnormalities and 160 matched controls. Blood, fat, muscle, skin, buccal swaps, urine will be collected and analyzed for DNA, RNA and methylation patterns.
- Conditions
- Sex Chromosome Abnormality, Klinefelter Syndrome, Turner Syndrome, Metabolic Disease
- Trial name
- EMKISCA (NCT05425953)
- Testing
- No intervention other than obtaining biopsies
- Where
- Denmark
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
PreDiabetes
Intestinimonas for Prevention of Type 2 Diabetes Mellitus
The study aims to assess the effects of a microbiota-based product containing Intestinimonas in adults with pre-diabetes. The purpose is to determine the safety and efficacy of the microbiota-based product on insulin sensitivity…
- Trial name
- NCT04495972
- Testing
- Intestinimonas-capsules
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Caelus Pharmaceuticals BV
MAFLD, Liver Fibrosis
Incidence of Liver Disease-Related Outcomes in People With HIV
Antiretroviral therapy can effectively control the replication of HIV, prolong the lifespan of patients infected with HIV, and improve their quality of life.At the same time, non-AIDS-related diseases such as diabetes and chronic…
- Conditions
- MAFLD, Liver Fibrosis, MASH, HIV
- Trial name
- PWH (NCT06940375)
- Testing
- Abdominal ultrasound , Fibroscan and body composition analysis examination
- Where
- China
- Volunteers
- 315 people
- Sponsor
- Shanghai Public Health Clinical Center
Fatty Liver
Resveratrol in Patients With Non-alcoholic Fatty Liver Disease
Non-alcoholic fatty liver disease (NAFLD) and fatty liver hepatitis (NASH) are very common in the Western world and strongly associated with obesity. No known effective treatment is known.
- Trial name
- LIRMOI3 (NCT01464801)
- Testing
- Resveratrol
- Where
- Denmark
- Volunteers
- 28 people
- Sponsor
- University of Aarhus
Behcet Disease, Antineutrophil Cytoplasmic Antibody (ANCA) Positive Vasculitis
Armenian NAtionwide REGistry of Systemic Autoimmune and Autoinflammatory Diseases
Longitudinal prospective multicenter Armenian registry of systemic autoimmune, autoinflammatory diseases with constitution of bio-banking.
- Conditions
- Behcet Disease, Antineutrophil Cytoplasmic Antibody (ANCA) Positive Vasculitis, Takayasu Arteritis, Giant Cell Arteritis
- Trial name
- NAREG (NCT05904301)
- Testing
- Usual medical management of patients, additional blood and stool samples for biobanking
- Where
- 6 sites in Armenia
- Volunteers
- 800 people
- Sponsor
- Santé Arménie French-Armenian Research Center
Metabolic Syndrome, Insulin Resistance
Effects of Consuming Sugar-Sweetened Beverages With Meals for 10 Weeks
The purpose of this study is compare the effects of consuming glucose- and fructose-sweetened beverages on appetite, body weight, body fat, and the amount of energy the body burns as well as effects on blood pressure, hormones…
- Conditions
- Metabolic Syndrome, Insulin Resistance, Dyslipidemia
- Trial name
- IPOP (NCT01165853)
- Testing
- Glucose, Fructose
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Obesity, Adolescent, Metabolic Syndrome
High-intensity Small-sided Soccer Games for Cardiometabolic Health in Adolescents With Metabolic Dysfunction
Pediatric obesity is considered one of the most important public health problems worldwide due to its high prevalence and associated comorbidities.
- Trial name
- NCT06377137
- Testing
- Small-sided soccer games groups (SSSG), Traditional soccer training groups (TSG)
- Where
- Portugal
- Volunteers
- 51 people
- Sponsor
- Universidade do Porto
Schizophrenia, Metabolic Syndrome
Effect on Metabolic Parameters of Abilify in SPR
To measure the long-term changes in weight and plasma lipids after switching antipsychotic treatment to aripiprazole
- Trial name
- NCT00569764
- Where
- 2 sites in South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National Hospital
Metabolic Syndrome, Testicular Cancer
Study of Testosterone vs Placebo in Testicular Cancer Survivors
The overall purpose of the study is to evaluate the effect of 12 months testosterone replacement therapy in testicular cancer survivors with mild Leydig Cell Insufficiency in order to reduce the risk of cardiovascular disease.
- Conditions
- Metabolic Syndrome, Testicular Cancer, Leydig Cell Failure in Adult
- Trial name
- Einstein (NCT02991209)
- Testing
- Testosterone
- Where
- Denmark
- Volunteers
- 69 people
- Sponsor
- Mikkel Bandak
Metabolic Syndrome
Metabolic Syndrome and Functional Food
High blood sugar and adiposity are part of Metabolic syndrome (about 24% of adults harbor it). The main approach, weight reduction, is often unattainable.
- Trial name
- NCT00916175
- Testing
- P1&P2, P1&CC, AG&P2
- Where
- 2 sites in Mexico
- Volunteers
- 125 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Metabolic Syndrome, Obesity
Glypican4 and CTRP5 in Metabolic Syndrome and the Effect of Exercise on These Adipokines
Glypican4, CTRP3, CTRP5 are emerging novel adipokines mediating obesity and inflammation related disorders. RBP4 and adiponectin are well known important adipokines.
- Trial name
- NCT01688622
- Testing
- 3months Exercise
- Where
- South Korea
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Korea University
Metabolic Syndrome
Clinical Study on Wuling Powder in Treating Metabolic Syndrome of Spleen Deficiency and Dampness
In this study, a randomized, partially double-blind, controlled, multi-center clinical research method was used. A total of 4 groups were designed, namely, single decoction group, co-decoction group, powder group and simulation…
- Trial name
- NCT04812236
- Testing
- Wulingsan single decoction granules, Wulingsan co-decoction granules, Wuling Powder
- Volunteers
- 320 people
- Sponsor
- Jiangsu Famous Medical Technology Co., Ltd.
Morbid Obesity, Vertical Sleeve Gastrectomy
Metabolic Syndrome, Bile Acids, Hepatocellular Carcinoma and Cholangiocarcinoma
Increasing rates of highly malignant hepatocellular carcinoma (HCC) and biliary tract cancers (GBTC) observed in Western populations may be related to obesogenic lifestyle factors and their metabolic consequences, such as…
- Conditions
- Morbid Obesity, Vertical Sleeve Gastrectomy, Metabolic Syndrome, Hepatocellular Carcinoma
- Trial name
- METSLIVER (NCT02730611)
- Where
- France
- Volunteers
- 124 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris