Clinical trials: Metabolic Disorder, Glucose
Cystic Fibrosis
Absorption and Safety With Sustained Use of RELiZORB Evaluation (ASSURE) Study
Protocol 0000498: Multicenter, open label study to evaluate the effect of sustained RELiZORB (immobilized lipase) cartridge use during enteral feeding on fat absorption, as well as safety and tolerability of sustained RELiZORB…
- Trial name
- ASSURE (NCT02750501)
- Testing
- RELiZORB (immobilized lipase) cartridge, Impact Peptide 1.5
- Where
- 10 sites in United States
- Volunteers
- 49 people
- Sponsor
- Alcresta Therapeutics, Inc.
Type 2 Diabetes, Hypertension
Impact of Clinical Pharmacist-Led Intervention on Management of Diabetic Hypertensive Patients in Eastern Nepal
Diabetic-Hypertensives are at a higher risk of premature microvascular and macrovascular complications than diabetes alone. Proper lifestyle management, diet, disease monitoring, and medication adherence is essential in achieving…
- Trial name
- NCT05707481
- Testing
- Clinical Pharmacist-Led Educational Intervention
- Where
- Nepal
- Volunteers
- 92 people
- Sponsor
- Chettinad Academy of Research and Education (Deemed to be University)
Type 1 Diabetes
Study of Offspring of Women With Type 1 Diabetes
There is an increasing trend in the society for developing obesity, type 2 diabetes and cardiovascular diseases. It is therefore important to identify the risk factors behind this tendency.
- Trial name
- EPICOM (NCT01559181)
- Where
- 3 sites in Denmark
- Volunteers
- 584 people
- Sponsor
- Odense University Hospital
PreDiabetes
Efficacy and Safety of Digital Therapeutic in Adults With Prediabetes
The study aims to evaluate the efficacy and safety of a digital therapeutic (TH-001) for adult individuals with prediabetes.
- Trial name
- NCT05668819
- Testing
- TH-001
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Tesu Saglik Teknolojileri A.S.
PreDiabetes, Obesity, Childhood
Conventional and Metabolomic Predictors of Prediabetes & Insulin Resistance
The purpose of this study is to evaluate the longitudinal test performance of an array of conventional biomarkers of glycemia, including Hemoglobin A1c (HbA1c), and novel metabolomic biomarkers for identifying progression of…
- Trial name
- NCT05055219
- Where
- United States
- Volunteers
- 772 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Diabetes Mellitus, Hypertension
Artificial Intelligence Guided Personalised Medicine in Patients With Hypertension and Diabetes
Hypertension and diabetes are chronic diseases that require long-term management and disease control is often sub-optimal, leading to complications which place additional burden on patients and the healthcare system.
- Trial name
- NCT04769141
- Testing
- CURATE.AI
- Volunteers
- 40 people
- Sponsor
- Alexandra Hospital
Diabetes Mellitus Type 1
A Monocenter, Open-Label Glucose Clamp Study Examining the Metabolic Effect of Insulin Infusion Intervals for Basal Insulin Infusion in Patients With Type I Diabetes
This crossover, glucose-clamp study will investigate the impact of different basal insulin infusion rates on glucose control employing insulin pumps with different insulin delivery regimen.
- Trial name
- NCT00772356
- Testing
- Accu-Chek Spirit Insulin Pump, Comparator insulin pump
- Where
- Germany
- Volunteers
- 14 people
- Sponsor
- Hoffmann-La Roche
Hyperglycemia, Renal Transplant Complication Primary Non-Function
Semaglutide Treatment for Hyperglycaemia After Renal Transplantation
Background: Post-transplant hyperglycaemia occurs frequently in renal transplant recipients within the first two weeks after transplantation.
- Conditions
- Hyperglycemia, Renal Transplant Complication Primary Non-Function, Diabetes
- Trial name
- Sema-RTx (NCT05702931)
- Testing
- Semaglutide 14 MG [Rybelsus]
- Where
- Denmark
- Volunteers
- 104 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Obesity, Type 2 Diabetes
MagDI Australia Study
The objective of the MagDI Australia Study is to evaluate the feasibility / performance, safety, and initial efficacy of the MagDI System in eligible participants who are indicated for a duodeno-ileal (small bowel) side-to-side…
- Trial name
- NCT06473831
- Testing
- Magnet System, DI Biofragmentable
- Where
- 4 sites in Australia
- Volunteers
- 25 people
- Sponsor
- GT Metabolic Solutions, Inc.
Cardiac Surgery, Insulin Resistance
Impact of Preoperative Oral Carbohydrate Loading on Insulin Resistance in Adult Cardiac Surgery Patients
The goal of this clinical trial is to investigate the effect of preoperative oral carbohydrate on insulin resistance in adult cardiac surgery patients with a cardiopulmonary bypass machine.
- Trial name
- NCT07212153
- Testing
- Oral Carbohydrate Drink (Maltodextrin)
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Rifdhani Fakhrudin Nur
Diabetes Type 2
Biphasic Insulin Aspart Versus NPH Plus Regular Human Insulin in Type 2 Diabetic Patients
Glycemic control is fundamental in the management of diabetes mellitus .If lifestyle intervention and full tolerated doses of one or two oral glucose lowering drugs (OGLDs) fail to achieve or sustain glycemic goals, insulin…
- Trial name
- NCT01889095
- Testing
- BIAsp 30, NPH/Reg
- Where
- Iran
- Volunteers
- 160 people
- Sponsor
- Tehran University of Medical Sciences
Obesity, Diabetes, Nutrition, Physical Health
Effects of Environmental Opportunities and Barriers on Physical Activity, Fitness, and Health in Hispanic Children in Wisconsin
This is a pilot community-based research study to examine the effects of specific environmental and social factors on physical activity, fitness, and health of middle school Hispanic children living in an inner-city community.
- Trial name
- NCT01180972
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Diabetes
Building a Behavioural Intervention Programme to Improve Self-Management of Diabetes
Effective control of diabetes requires patients to change their daily behaviour. The investigators propose an intervention programme for behavioural change with two components, targeting motivation and implementation.
- Trial name
- NCT05203575
- Testing
- Fast-forwarding in Cycle 1, Goal-Setting plus Weekly Nudge in Cycle 1, Fast-forwarding in Cycle 2
- Where
- Singapore
- Volunteers
- 225 people
- Sponsor
- National University of Singapore
Type 2 Diabetes Mellitus, Hypertension
Evaluation of Improved Outcomes Among Ambulatory Diabetes and/or Hypertensive Patients - an Intervention Study (CPCLINT)
The goal of this interventional study is to compare improved outcomes among diabetes and/or hypertensive patients sequel to educational intervention.
- Trial name
- CPCLINT (NCT05996601)
- Testing
- Educational intervention
- Where
- Nigeria
- Volunteers
- 400 people
- Sponsor
- University of Ibadan
Haemodialyzed, Type 2 Diabetes
A Prospective, Multicenter, Randomized, Open-label Study of 12 Week Duration to Evaluate the Effect of VILDagliptin Added to Insulin on Glycaemic Control in haemoDIALyzed Patients With Type 2 Diabetes: Probe Analysis of CGM
Diabetes is a major concern for dialysis units, as it is now the most common cause of end-stage renal disease in France. In 2010 at initiation of dialysis treatment, more than one patient out of two had at least one…
- Trial name
- NCT02176681
- Testing
- Vildagliptin (Galvus), Insulin
- Where
- 13 sites in France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Strasbourg, France
Diabetes Mellitus, Renal Failure
The Effects of Hemodialysis on Serum Sclerostin Levels
Background: Parathyroid hormone (PTH) and 1,25-dihydroxy vitamin D (1,25-OHD) as well as mineral bone metabolism modulators like sclerostin are thought to play an important role in in diabetic patients with chronic renal failure.
- Conditions
- Diabetes Mellitus, Renal Failure, Hemodialysis Access Failure
- Trial name
- sclerostin (NCT03952819)
- Testing
- serum sclerostin
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Obesity
Egg Diet to Improve Metabolic Health and Function
The purpose of this study is to determine the effects of change in diet quality (carbohydrate restriction versus fat restriction) on body composition, fat distribution, cardiometabolic risk factors, physical function, and quality…
- Trial name
- NCT02760641
- Testing
- Egg-based diet (EBD), Carbohydrate-based diet (CBD)
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Diabetes Mellitus, Type 2, Diabetes Complications
Electronic Diabetes Tune-Up Group (eDTU) for African Americans
The primary aims of this study are: 1. To test the acceptability and feasibility of the electronic DTU intervention (eDTU) that has been adapted for cultural relevance and online delivery compared to waitlist control and the…
- Trial name
- NCT06321029
- Testing
- Diabetes Tune-Up Group
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Indiana University
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Basal Insulin And Compensation Glycemic In Diabetic Patients In Basal Bolus Outpatient.
Multicentric, observational, cross-sectional study in Italy. The aims are to evaluate the basal/total ratio of daily insulin dose (b/T) in diabetic outpatients type 1 (T1) and type 2 (T2) on basal-bolus regimen, by investigating…
- Trial name
- BASAL (NCT03489031)
- Volunteers
- 1,036 people
- Sponsor
- Associazione Medici Endocrinologi
Diabetic Nephropathy
Open Label Tolerability and Safety Study of KRX-101 in Australia, New Zealand, and Hong Kong
The purpose of this study is to assess the tolerability and safety of KRX-101 in treating persistent microalbuminuria in type 2 diabetic patients who are also being treated with stable, maximum tolerated doses of either ACE…
- Trial name
- NCT00462202
- Testing
- sulodexide
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- Keryx Biopharmaceuticals
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