Clinical trials: Metabolic Disorder, Glucose
Diabetes Mellitus Type 1
Assessment of the Neurovascular Microcirculatory Response in Diabetes Type 1 Patients
This study aims to see whether or not the diabetes 1 patients have a neurovascular microcirculatory dysfunction using various microvascular tests which have been previously validated.
- Trial name
- NEURODIAB1 (NCT02538120)
- Testing
- Microvascular assessment
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Prediabetes / Type 2 Diabetes
Health Assessment of Low Glycaemic Index - High Protein Rice to Enhance Glycemic Control Through Nutrition
Type 2 Diabetes (T2D) represents a critical public health challenge in Singapore, with prevalence projected to reach one million residents by 2050.
- Trial name
- HARVEST (NCT07663123)
- Testing
- Functional rice variaties
- Volunteers
- 225 people
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Diabetes Mellitus, Type 2
GODART Pilot and Feasibility
The purpose of this study is to pilot and assess the feasibility of implementing an artificial intelligence-assisted individualized lifestyle modification intervention for glycemic control in rural populations, which can be…
- Trial name
- GODART-P&F (NCT05344859)
- Testing
- Weekly Automated Health Coaching, Weekly Human Health Coaching, Adapted Reward Level
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of Alabama at Birmingham
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW-III All-comers Orsiro Safety and Performance Registry
This registry is a clinical post-market evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES).
- Trial name
- BIOFLOW-III (NCT01553526)
- Where
- 43 sites in Austria, Chile and 11 more
- Volunteers
- 1,356 people
- Sponsor
- Biotronik AG
Gestational Diabetes, Type 2 Diabetes
Abnormal Post-partum Glucose Metabolism After Gestational Diabetes Diagnosed Before or After 24 Weeks of Gestation
The main objective of the study is to estimate and compare the percentage of patients with abnormal glucose metabolism at 4-12 weeks postpartum between two groups: patients diagnosed with gestational diabetes before or after 24…
- Conditions
- Gestational Diabetes, Type 2 Diabetes, Glucose Intolerance
- Trial name
- DG Post-Partum (NCT01839448)
- Testing
- Post-partum oral glucose tolerance test
- Where
- 4 sites in France
- Volunteers
- 500 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Gestational Diabetes Mellitus
Myo-inositol for Reduction of Insulin Therapy in Gestational Diabetes Mellitus
Gestational diabetes mellitus (GDM) is defined as hyperglycemia first-diagnosed during pregnancy. Glycemic control reduces GDM-related complications.
- Trial name
- MYO-GDM (NCT03875755)
- Testing
- Myo Inositol
- Where
- 2 sites in France
- Volunteers
- 1,080 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes, Diabetes Mellitus, Type 2
A Trial to Investigate the Single Dose Pharmacokinetics of Insulin Degludec/Liraglutide Compared With Insulin Degludec and Liraglutide in Healthy Chinese Subjects
The main purpose of the trial is to compare the bioavailability (extent of drug absorption into the circulation) of insulin degludec and liraglutide as part of a combination product insulin degludec/liraglutide compared to the…
- Trial name
- NCT03292185
- Testing
- insulin degludec/liraglutide, insulin degludec, liraglutide
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Morbid Obesity
An Analysis of Lipid and Glucose Metabolism Following Bariatric Surgery
Bariatric surgery induce remarkable weight loss and improvement or resolution of type 2 diabetes. Obesity is the primary risk factor for type 2 diabetes, and 90% of all type 2 diabetics are obese.
- Trial name
- NCT02067585
- Testing
- Standardized Lipid meals
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University of Alberta
Gastric Retention
Residual Gastric Content After Holding of Glucagon-like Peptide-1 Receptor Agonists Before Elective Surgery
Glucagon-like peptide-1 agonists (GLP-1RA) are a family of medications used for diabetes and weight loss. One of their effect is to slow down stomach emptying.
- Trial name
- RESIDUAL (NCT06500143)
- Testing
- Gastric ultrasound
- Where
- Canada
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Obesity and Overweight, Obesity, Morbid
Impact of Nutritional Intervention With Probiotics and Prebiotics on Obesity.
Obesity is one of the most severe and prevalent non-communicable diseases worldwide, affecting an estimated one-third of the population in Spain.
- Conditions
- Obesity and Overweight, Obesity, Morbid, Metabolic Syndrome
- Trial name
- MicoBeBioticos (NCT06722443)
- Testing
- Probiotic, Prebiotic, Synbiotic
- Where
- Spain
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Fundación Pública Andaluza para la Investigación Biomédica Andalucía Oriental
Kidney Transplant; Complications
Dietary Intervention Trial Targeting Metabolic Syndrome After Kidney Transplantation
Kidney transplant recipients (KTR) have a considerably lower life expectancy as compared with the general population, primarily due to a high prevalence of cardiovascular diseases.
- Trial name
- DIETTX (NCT04698408)
- Testing
- high-protein, carbohydrate-reduced diet, Dutch Nutritional Guidelines
- Volunteers
- 30 people
- Sponsor
- University Medical Center Groningen
Diabetes
Comparative Glucose Clamp Study of Wockhardt's Insulin Human Regular for Injection and Actrapid, in Healthy Subjects.
The aim of this trial is to demonstrate bioequivalence of Wosulin R to Actrapid with regard to its total and to its maximum serum insulin concentrations.
- Trial name
- NCT00719108
- Testing
- Wosulin R, Actrapid
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Wockhardt
Type 1 Diabetes
Reactive Oxygen Species in the Pathogenesis of Diabetic Complications
Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy and incipient nephropathy in these models.
- Trial name
- NCT00703989
- Testing
- benfotiamine, α-lipoic acid
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Obesity, Overweight
A Study of LY3549492 in Adults With Obesity or Overweight With Type 2 Diabetes
The main purpose of this study, performed under the master protocol W8M-MC-CWMM (NCT06143956), is to evaluate the effects of treatment with LY3549492 compared to placebo in adult participants with obesity or who are overweight…
- Conditions
- Obesity, Overweight, Type 2 Diabetes
- Trial name
- NCT07030868
- Testing
- LY3549492
- Where
- 42 sites in United States, Argentina
- Volunteers
- 1 people
- Sponsor
- Eli Lilly and Company
Insulin Resistance, Hepatitis C
Effect of Hepatitis C Clearance on Insulin Resistance
Chronic hepatitis C infection has been linked to insulin resistance, which is the essential component of metabolic syndrome and type 2 diabetes mellitus.
- Trial name
- NCT04457050
- Testing
- Sofosbuvir 400 milligram, Daclatasvir 60 milligram, Ribavirin 400 milligram
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Alexandria University
Healthy, Prediabetic State
Effect of a Collagen Hydrolysate on Postprandial Blood Glucose Profile in Prediabetic and Healthy Subjects
To investigate the effect of two different dosages collagen hydrolysate (CH) on postprandial blood glucose and insulin profile in prediabetic and normo-glycaemic subjects.This will be investigated in a cross-over randomized…
- Trial name
- NCT05887791
- Testing
- Collagen hydrolysate
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Rousselot BVBA
Diabetes Mellitus Type 1
Use of Stem Cells in Diabetes Mellitus Type 1
Allogenic adipose derived mesenchymal stem cells will be injected into patients newly diagnosed with type 1 Diabetes Mellitus
- Trial name
- NCT02940418
- Testing
- Adipose mesenchymal cells with bone marrow mononuclear cells
- Where
- Jordan
- Volunteers
- 20 people
- Sponsor
- Sophia Al-Adwan
Type 2 Diabetes
A Study of OPC-262 in Patients With Type 2 Diabetes
The purpose of this clinical study is to evaluate the safety and efficacy of OPC-262 5 mg in patients with type 2 diabetes by repeated administration orally for 52 weeks.
- Trial name
- NCT01046318
- Testing
- OPC-262
- Where
- 3 sites in Japan
- Volunteers
- 100 people
- Sponsor
- Kyowa Kirin Co., Ltd.
Diabetes Mellitus, Type II
Effects of Fatty Acid Delivery on Heart Metabolism and Function in Type 2 Diabetes (T2DM
Type 2 Diabetes Mellitus (T2DM) is a disease that interferes with the body's proper production and use of insulin, a hormone needed to convert sugar into usable energy.
- Trial name
- T2DM (NCT00577590)
- Testing
- Metformin, Rosiglitazone, Lovaza
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Washington University School of Medicine
Diabetes Mellitus
A Study of a Non-invasive Glucose Measuring Device in Out-patient Settings
This explorative clinical investigation has been launched to collect spectral Raman data paired with validated glucose reference values in persons with diabetes.
- Trial name
- NCT04518813
- Testing
- Prototype 0.5
- Where
- Germany
- Volunteers
- 173 people
- Sponsor
- RSP Systems A/S
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