Clinical trials: Metabolic Disorder, Glucose
Diabetes Mellitus, Type 2
Effect on Glycemic Control of Inhaled Insulin Alone or Added to Dual Oral Therapy After Failure of Dual Oral Therapy.
To assess the impact on glucose control by inhaled insulin alone or added to two oral anti-diabetic agents in patients with type 2 diabetes who are not well controlled on 2 oral anti-diabetic agents.
- Trial name
- NCT00370565
- Testing
- Inhaled Human Insulin
- Where
- 52 sites in United States, Canada
- Volunteers
- 345 people
- Sponsor
- Pfizer
Type 1 Diabetes Mellitus, Depressive Symptoms
Internet-Based Cognitive Behavioral Therapy for Depressive Symptoms in Adolescents With Type 1 Diabetes Mellitus
This study evaluates the use of an established internet-based cognitive behavioral therapy intervention in a group of adolescents with type 1 diabetes and mild to moderate depressive symptoms.
- Trial name
- NCT03655067
- Testing
- CATCH-IT
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Texas Southwestern Medical Center
Type 1 Diabetes
Audio Health Engagement Analysis in Diabetes: The AHEAD Study
Despite multidisciplinary care and advancements in therapeutics and technology, health outcomes remain suboptimal in pediatric diabetes centers world-wide.
- Trial name
- NCT01938807
- Testing
- CareCoach mobile application to assist in diabetes management
- Volunteers
- 43 people
- Sponsor
- University of California, San Francisco
Gonarthrosis, Diabetes
The Role of SCUBE-1 in Ischemia-reperfusion Injury
One consequence of tissue damage caused by tourniquet is ischemia-reperfusion injury. Short-term ischemia leads to vasodilatation and reactive hyperemia resulting in post-ischemic reperfusion microcirculation failure and tissue…
- Trial name
- NCT03389607
- Testing
- spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Type 2 Diabetes
Improvement of Insulin Resistance With Traditional Chinese Treatment in Patients With Type 2 Diabetes
The purpose of this study is to evaluate the efficacy of Traditional Chinese Treatment(TCT) on insulin sensitivity and other related factors in type 2 diabetes by using an double-blind, randomized, parallel control and…
- Trial name
- NCT00704236
- Testing
- Coptis Chinensis, Astragalus mambranesceus, Lonicera Japonica (Traditional Chinese Treatment)
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Diabetic Foot
The Effect of Foot Care Training Given to Diabetic Hemodialysis Patients on Foot Care Behavior
Diabetic foot causes hospitalization, amputation and serious health problems in individuals. This situation also leads to loss of productivity of the individual, negatively.
- Trial name
- NCT06526936
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- University of Beykent
Liver Transplant; Complications, Diabetes Mellitus
Semaglutide vs Sitagliptin
The effect of once daily dosing of oral Semaglutide versus once daily dosing Sitagliptin on glycemic control, body weight, and safety and tolerability will be compared in Liver Transplant Recipients with poorly-controlled…
- Conditions
- Liver Transplant; Complications, Diabetes Mellitus, NASH - Nonalcoholic Steatohepatitis, NAFLD
- Trial name
- NCT05195944
- Testing
- Semaglutide Treatment, Sitagliptin 100mg
- Where
- Canada
- Volunteers
- 58 people
- Sponsor
- University Health Network, Toronto
Type 2 Diabetes
Liraglutide Actions on the Liver: Effects on Glucose Phosphorylation
Type 2 diabetes is a chronic disease that has reached epidemic proportions. In order to improve our strategies for preventing and treating type 2 diabetes the investigators need to better understand the mechanism of this disease…
- Trial name
- NCT02198209
- Testing
- Liraglutide
- Where
- United States
- Sponsor
- Cedars-Sinai Medical Center
Periodontal Diseases, Diabetes Mellitus
Anti Oxidant Enzymes and Total Antioxidant Levels in Diabetes Mellitus Type II Patients and Healthy Individuals With Periodontitis
To evaluate the role of antioxidants - superoxide dismutase, catalase, glutathione and total anti oxidant levels in the serum of chronic periodontitis patients and chronic periodontitis with DM Type II patients, then to compare…
- Conditions
- Periodontal Diseases, Diabetes Mellitus, Enzyme Disorder
- Trial name
- NCT04180332
- Testing
- Blood sample
- Where
- India
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ajman University
Bariatric Surgery Candidate, Diet Modification
Effects of Wolffia Globosa (Mankai) in Patients Undergoing Bariatric Surgery.
Candidates to bariatric surgery at The Bariatric and Metabolic Institute at Cleveland Clinic Florida are prescribed a high protein liquid diet for two weeks preoperatively and 2 weeks postoperatively.
- Trial name
- NCT03999632
- Testing
- Dietary modification with introduction of Mankai
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Cleveland Clinic Florida
Type II Diabetes Mellitus, Gestational Diabetes Mellitus
Intrapartum Glycemic Control With Insulin Infusion Versus Rotating Fluids
This study will determine whether rotating intravenous (IV) fluid is better than receiving insulin to control a baby's blood sugar after delivery in laboring women with diabetes.
- Trial name
- NCT03912363
- Testing
- Rotating fluids protocol, Insulin infusion protocol
- Where
- 2 sites in United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Diabetes Mellitus, Type 2, Insulin Resistance
Evaluation of Intra-Abdominal Fat Extraction Using HydraSolve T2D™ in Obese Subjects With Type 2 Diabetes
This study will investigate the safety and efficacy of the investigational use of the HydraSolve T2D™ System in improving blood glucose control and insulin resistance in patients with obesity (Class 1, BMI 30-39.9 kg/m2) and type…
- Trial name
- NCT03953963
- Testing
- HydraSolve T2D™
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Medality Medical
Diabetes
BRInging the Diabetes Prevention Program to GEriatric Populations - PILOT
The purpose of this pilot study is to test the feasibility of implementing a telehealth adaption of the Diabetes Prevention Program (DPP) intervention among 30 NYC senior center members.
- Trial name
- BRIDGE (NCT03524404)
- Testing
- 6 Week Intervention
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- NYU Langone Health
Brain Injuries, Hyperglycemia
Intensive Versus Nonintensive Insulin Therapy for Hyperglycemia After Traumatic Brain Injury
An increase in blood glucose is a common clinical symptom in patients following traumatic brain injury. Studies confirm that death after traumatic brain injury was not only associated with nerve injury, but also correlated with…
- Trial name
- NCT02161055
- Testing
- Insulin
- Where
- 2 sites in China
- Volunteers
- 144 people
- Sponsor
- Lianyungang Oriental Hospital
Type 2 Diabetes Mellitus
Single Cohort, 2-Period Study to Assess Pharmacokinetics of Metformin Alone and in Combination With Ranolazine 500 mg
The purpose of this study is to evaluate the effect of steady-state ranolazine 500 mg bid on the steady state pharmacokinetics (PK) of metformin in subjects with type 2 diabetes mellitus (T2DM).
- Trial name
- NCT01546558
- Testing
- Metformin, Ranolazine
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Gilead Sciences
Diabetes Mellitus
CoDiab-VD: a Population-based Cohort on Quality of Care of Patients With Diabetes in the Canton of Vaud (Switzerland)
Diabetes, one of the most prevalent chronic disease (~ 9% worldwide), represents a major public health burden in terms of morbidity, disability and mortality.
- Trial name
- CoDiab-VD (NCT01902043)
- Where
- Switzerland
- Volunteers
- 1,033 people
- Sponsor
- University of Lausanne Hospitals
Neuropathy, Diabetic, Diabetes Mellitus, Type 2
DECODING Study (Dermal Electrochemical Conductance in Diabetic Neuropathy)
Diabetes mellitus is the leading cause of polyneuropathy in the Western world. Diabetic neuropathy is a frequent complication of diabetes and may have great clinical transcendence due to pain and possible ulceration of the lower…
- Trial name
- DECODING (NCT03495089)
- Testing
- dermal electrochemical conductance (DEC), Monofilament testing
- Where
- 3 sites in Spain
- Volunteers
- 147 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Metabolic Syndrome
Mesoglycan, Vascular Reactivity and Metabolic Syndrome
The purpose of the study was to characterize the action of mesoglycan on vascular endothelium through the non-invasive assessment of vascular reactivity humeral artery by comparing effects of mesoglycan on Flow Mediated…
- Trial name
- NCT02254850
- Testing
- Flow Mediated Dilation, Mesoglycan
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Federico II University
Hyperglycemia, Cardiovascular Diseases
REsearching Coronary REduction by Appropriately Targeting Euglycemia (RECREATE Pilot Study)
Insulin will safely reduce glucose levels in patients with acute ST-elevation myocardial infarction and admission hyperglycemia.
- Conditions
- Hyperglycemia, Cardiovascular Diseases, Myocardial Infarction
- Trial name
- RECREATE Pilot (NCT00640991)
- Testing
- glulisine insulin, glargine insulin
- Where
- 13 sites in Argentina, Canada and 1 more
- Volunteers
- 500 people
- Sponsor
- Population Health Research Institute
Coronary Heart Disease, Diabetes
OPtimized Stenting Using Intravascular Ultrasound(IVUS) in Long lEsion: Rationale for Simplified criteriA
Rationale IVUS has shown to be efficient for bare metal stent deployment, but has not been specifically studied for Drug Eluting Stents.
- Conditions
- Coronary Heart Disease, Diabetes, Vascular Lesions, Chronic Total Occlusion of Coronary Artery
- Trial name
- OPERA (NCT01861860)
- Testing
- TAXUS™ Element long stent
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
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