Clinical trials: Metabolic Disorder, Glucose
Type 1 Diabetes
A Study of LY900014 and Insulin Degludec in Participants With Type 1 Diabetes
In this study, participants with type 1 diabetes (T1D) will take the study drug LY900014 and insulin degludec. The reason for this study is to evaluate the amount of time with glucose values within target range.
- Trial name
- NCT04585776
- Testing
- LY900014, Insulin Degludec
- Where
- 3 sites in United States
- Volunteers
- 31 people
- Sponsor
- Eli Lilly and Company
Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus
GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes
The purpose of this study is to check that a new insulin pump, called NMX8, is safe when used with a continuous glucose monitoring sensor called Disposable Sensor 5/Simplera Sync in people with diabetes.
- Trial name
- NCT07228117
- Testing
- MiniMed™ NMX8-AID System with DS5™/Simplera Sync™
- Where
- 33 sites in United States, Australia and 1 more
- Volunteers
- 389 people
- Sponsor
- Medtronic MiniMed, Inc.
Diabetes
Bauhinia Forficata in Diabetic Patients
Among the plants most used in folk medicine for the treatment of diabetes are the species of the genus Bauhinia (Fabaceae), popularly known in Brazil as "pata-de-vaca".
- Trial name
- NCT02760017
- Testing
- B. forficata
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude
Prediabetic State
Effects of Clinical Pilates Exercises on Glycemic Control, Blood Lipids and Physical Fitness Parameters in Prediabetes
To examine the effects of clinical pilates exercise on glycemic control, blood lipids and physical fitness parameters in prediabetics.
- Trial name
- NCT06452940
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Eastern Mediterranean University
Chronic Conditions, Multiple
Implications of Stress Management Program
Previous studies indicated that patients with diabetes mellitus and hypertension had higher level of perceived stress, used maladaptive coping strategies and poor health-related quality of life.
- Trial name
- NCT04978974
- Testing
- Stress Management Program
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- University of Gujrat
Type 1 Diabetes
Study of the Acute Metabolic Effect of Exenatide in Type 1 Diabetes
The study is designed as an open labeled pilot trial to analyze the acute responses of glucose, GLP-1, GIP, insulin secretory,and glucagon to a mixed meal tolerance test (MMTT) or intravenous glucose tolerance tests (IVGTT) with…
- Trial name
- NCT01855490
- Testing
- Exenatide
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Yale University
Mental Health Issue, Depression
Development and Validation of Psycho-Social Program (PSP)
The study aims to determine the effectiveness of a structured psycho-social program (PSP) in improving mental health outcomes among patients with Type 2 diabetes mellitus (T2DM).
- Conditions
- Mental Health Issue, Depression, Diabetes Distress, Quality of Life
- Trial name
- PSP-T2DM (NCT07456410)
- Testing
- Psycho-Social Program
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Government College University Faisalabad
Type 2 Diabetes Mellitus
Does Exercise Timing Affect Glucose Levels in People With Diabetes?
It is not clear if there is an optimal time for exercise to improve blood glucose profiles in people with type 2 diabetes. The goal of this study is to compare post meal and 24-hour glucose levels in 4 different conditions…
- Trial name
- NCT03626155
- Testing
- Walking, Seated Control
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of Alberta
Diabetes, Diabetes Mellitus, Type 2
Comparison of Two NN5401 Formulations Versus Insulin Glargine, All in Combination With Metformin in Subjects With Type 2 Diabetes
This trial is conducted in Europe. The aim of this trial is to compare two NN5401 (SIAC, insulin degludec/insulin aspart) formulations with each other and with insulin glargine, all in combination with metformin in insulin naive…
- Trial name
- NCT00614055
- Testing
- insulin degludec/insulin aspart, insulin glargine, metformin
- Where
- 28 sites in France, Germany and 3 more
- Volunteers
- 178 people
- Sponsor
- Novo Nordisk A/S
Bariatric Surgery (Gastric Bypass), Overweight
The Effect of Different Macronutrients on Gastrointestinal Hormone Secretion After Gastric Bypass Operation
The purpose of this study is to determine the type of macronutrient (carbohydrate, lipid or protein) that most potently stimulates the endogen secretion of different gut hormones (primary outcome = Glucagon-Like peptide-1) in…
- Trial name
- NCT02372526
- Testing
- Mealtest: High protein 200 kcal 200 ml liquid meal consumed during 10 minutes, Mealtest: High fat 200 kcal 200 ml liquid meal consumed during 10 minutes, Mealtest: High carbohydrate 200 kcal 200 ml liquid meal consumed during 10 minutes
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Kirstine Nyvold Bojsen-Moeller
Diabetes Mellitus
A Mobile and Web-Based Clinical Decision Support and Monitoring System for Diabetes Mellitus Patients in Primary Care
The purpose of the study is to develop a user-friendly, comprehensive, fully integrated web and mobile-based Clinical Decision Support and Monitoring System (CDSMS) for DM diseases screening, diagnosis, treatment and monitoring…
- Trial name
- NCT02917226
- Testing
- Clinical decision support and monitoring system
- Sponsor
- Dokuz Eylul University
Dyslipidemia, Atherosclerosis
Choline Fenofibrate and Carotid Atherosclerosis in Patients With Type 2 Diabetes and Combined Dyslipidemia
This is a randomized controlled study to assess the effect of choline fenofibrate compared with policosanol in Korean T2DM patients with asymptomatic atherosclerosis.
- Conditions
- Dyslipidemia, Atherosclerosis, Diabetes Mellitus, Type 2
- Trial name
- NCT05365425
- Testing
- Choline fenofibrate, Policosanol
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Seoul National University Bundang Hospital
Heart Failure, Hyperuricemia
Treatment of Hyperuricemia in Patients With Heart Failure
The study aims to assess (I) the contribution of UA itself to the CHF pathophysiology and (II) to test the effect of lowering UA by uricosuric treatment in CHF.
- Trial name
- NCT00422318
- Testing
- Benzbromarone (drug)
- Where
- Japan
- Sponsor
- Tottori University Hospital
Type 2 Diabetes
Change of Lifestyle by Persons in Risk of Type 2 Diabetes
We know that changing lifestyle can prevent type 2 diabetes. The challenge is how to help people changing their lifestyle. We have people in 2 groups: half of them is meeting in grops of 10 persons (interventiongroup), the other…
- Trial name
- NCT00202748
- Testing
- Increase in activity to control weight, Increase in activity to control weight.
- Where
- Norway
- Volunteers
- 220 people
- Sponsor
- Sorlandet Hospital HF
Diabetes Mellitus
PRECISE: A Prospective, Multi-Center Evaluation of the Accuracy of a Novel Continuous Implanted Glucose Sensor
The purpose of this clinical investigation is to evaluate the accuracy of the Senseonics Continuous Glucose Monitoring System (Senseonics CGM System) measurements when compared with reference standard measurements (YSI glucose…
- Trial name
- PRECISE (NCT02154126)
- Testing
- Continuous Glucose Monitoring Device (Senseonics)
- Where
- Netherlands
- Volunteers
- 81 people
- Sponsor
- Senseonics, Inc.
Heart Failure, Type 2 Diabetes
Exercise, Heart Failure, and Type 2 Diabetes
The purpose of this study is to understand the differences in how patients with heart failure respond to exercise training compared to patients with heart failure and type 2 diabetes.
- Trial name
- NCT02122835
- Testing
- aerobic exercise training
- Where
- United States
- Sponsor
- Duke University
Type 1 Diabetes Mellitus
The PK and PD of Dapagliflozin Therapy in Combination With Insulin in Japanese Subjects With T1DM
This randomized, single-blind, 3 arm, parallel group, placebo controlled PK/PD study will enrol 30 Japanese male and female patients with T1DM and age 18 to 65 years, with inadequate glycemic control on insulin defined as HbA1c ≥…
- Trial name
- NCT02582840
- Testing
- Dapagliflozin 5mg, Dapagliflozin 10mg
- Where
- Japan
- Volunteers
- 42 people
- Sponsor
- AstraZeneca
Diabetes Mellitus, Schizophrenia
Diabetes Screening, Risk Management and Disease Management in a High-Risk Mental Health Population
Family physicians are the primary health care providers for complex patients such as persons with serious mental illness. The psychiatric needs of these patients could take attention away from management of health problems and…
- Conditions
- Diabetes Mellitus, Schizophrenia, Psychotic Disorders
- Trial name
- NCT00253240
- Testing
- Screening, Management
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Diabetes Mellitus
Using Networks, Informatics, Technology, and Education in Care for People With Diabetes
The costs of diabetes care (in health care dollars \& human suffering) in the United States are second only to mental illness. Randomized control trials \& observational studies have shown that glycemic control is predictive of…
- Trial name
- NCT00421850
- Testing
- UNITED Planned Care
- Where
- United States
- Volunteers
- 3,491 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Gestational Diabetes
EMERGE Mothers and Kids
The EMERGE Mothers and Kids study is a follow-up to the EMERGE trial of women with GDM (N=535) that aimed to determine the effect of the addition of metformin compared to placebo on insulin initiation rates, maternal weight gain…
- Trial name
- NCT06327191
- Testing
- No intervention as the study is observational.
- Where
- Ireland
- Volunteers
- 370 people
- Sponsor
- National University of Ireland, Galway, Ireland
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