Clinical trials: Metabolic Disorder, Glucose
Type 2 Diabetes Mellitus
GLP-1 and Non-exercise Activity Thermogenesis in RHZ
Rationale: Treatment with glucagon-like peptide 1 (GLP-1) has been shown to reduce plasma glucose levels to a further extent when added to standard therapy in type 2 diabetes mellitus.
- Trial name
- NCT01638260
- Testing
- Liraglutide, NEAT
- Where
- Netherlands
- Volunteers
- 22 people
- Sponsor
- Maastricht University Medical Center
Diabetes, Diabetes Mellitus
QBSAfe: A Novel Approach to Diabetes Management Focused on Quality of Life, Burden of Treatment, Social Integration and Avoidance of Future Events
The purpose of this study is to co-develop a toolkit (known as the QBSAfe toolkit) with patients, family caregivers, and clinicians that focuses on palliating symptoms, alleviating burden of treatment, facilitating social…
- Trial name
- QBSAfe (NCT04514523)
- Testing
- QBSAfe Toolkit
- Where
- 3 sites in United States
- Volunteers
- 91 people
- Sponsor
- Yale University
Sleep, Insomnia
Treatment of Insomnia and Glucose Metabolism
Available data suggest that obtaining adequate sleep is associated with a better ability of the body to use carbohydrates as a source of energy and a lower risk of developing diabetes.
- Conditions
- Sleep, Insomnia, Insulin Resistance
- Trial name
- NCT00724282
- Testing
- Eszopiclone
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Diabete Mellitus
Impact of Diabetes Continuing Education on Primary Health Care Physicians' Knowledge, Attitudes and Practice
The main objective is to evaluate the effectiveness of a continuing education program on the Knowledge, Attitudes and Practices of primary health care physicians towards a high quality of diabetes care in Aseer region, Saudi…
- Trial name
- NCT04027062
- Testing
- Diabetes Continuing Education Intervention
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- King Khalid University
Diabetes Mellitus, Type 2
Gastric Emptying - Implications for the Pathogenesis of Type 2 Diabetes
People of black African and Caribbean descent have a greater risk of developing type 2 diabetes than white Europeans. The aim of this study is to increase our knowledge of how the condition may arise, and what underlies this…
- Trial name
- NCT03864562
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Gestational Diabetes, Breast Feeding
Exclusive Breastfeeding Improves Puerperal Glucose Metabolism in Pregnant Women With Gestational Diabetes Mellitus and Links to Lipids Composition
Breastfeeding could effectively be associated with a lower risk of future type 2 diabetes (T2D) in women with gestational diabetes mellitus (GDM), but the short-term protective impact of puerperal breastfeeding on maternal…
- Conditions
- Gestational Diabetes, Breast Feeding, Lipid Metabolism Disorders
- Trial name
- NCT05629403
- Testing
- observe
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Nanjing Medical University
Type 1 Diabetes
Insulin Omission Surrogate (iOS)
Type 1 Diabetes management is requiring and implies numerous lifestyle modifications. Insulin restriction to control weight is a frequent phenomenon, affecting up to 40% of PWT1D.
- Trial name
- iOS (NCT05476861)
- Where
- Canada
- Volunteers
- 751 people
- Sponsor
- Laval University
Diabetes Mellitus, Gastroparesis
Effect of Electroacupuncture in Diabetic Patients With Gastroparesis
In this study, we aim at evaluating the effect of electroacupuncture in diabetic patients with gastroparesis. Patient-based symptom severity measure, serum parameters and solid-phase gastric emptying time are measured to evaluate…
- Trial name
- NCT00227383
- Testing
- Electroacupuncture (device)
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- China Medical University Hospital
Type 1 Diabetes Mellitus
Pharmacologic Response and Safety of Inhaled Insulin in Type 1 Diabetes
The purpose of this study was to compare the pharmacokinetic (PK) response after inhaled insulin administration with 3 different inhalation regimens and with subcutaneous insulin administration.
- Trial name
- Samba-01 (NCT02713841)
- Testing
- inhaled human insulin (INH), sc insulin lispro (LIS)
- Volunteers
- 12 people
- Sponsor
- Dance Biopharm Inc.
Overweight, Obesity
Mitochondrial Methylation in Type 2 Diabetes
The overarching goal of this proposal is to determine whether DNA methylation of the mitochondrial DNA impairs mitochondrial function in insulin resistant states such as overweight/obesity and type 2 diabetes.
- Conditions
- Overweight, Obesity, Diabetes Mellitus, Type 2, Insulin Resistance
- Trial name
- NCT04126551
- Testing
- Methylation status
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Diabetes Mellitus Type 1
ZP4207(Dasiglucagon) Administered to T1D Patients to Assess the PK and PD Compared to Marketed Glucagon
The trial is a single-centre, randomised, sequential, cross-over trial assessing pharmacokinetic and pharmacodynamic responses after micro-doses of ZP4207 (dasiglucagon*) administered subcutaneously to patients with type 1…
- Trial name
- NCT02916251
- Testing
- ZP4207(dasiglucagon) glucagon analogue, Glucagon (Native glucagon)
- Where
- Germany
- Volunteers
- 38 people
- Sponsor
- Zealand Pharma
Metabolic Syndrome X, Type 2 Diabetes Mellitus
Effect of Fish Oil on Insulin Sensitivity
The purpose of this study is to determine whether a prolonged (9 month) high (6g/d) of marine oil improves insulin sensitivity and glucose control in subjects with impaired glucose regulation.
- Conditions
- Metabolic Syndrome X, Type 2 Diabetes Mellitus, Sarcopenia
- Trial name
- NCT01241474
- Testing
- EPAX 6000 (marine omega 3 EPA/DHA fatty acid concentrates, Maize (corn) oil
- Where
- United Kingdom
- Volunteers
- 34 people
- Sponsor
- University of Aberdeen
Dysmetabolic Iron Overload Syndrome, Genetic Hemochromatosis
Effects of Polyphenols on Iron Absorption in Iron Overload Disorders.
Dysmetabolic iron overload syndrome and genetic hemochromatosis are frequent causes of iron overload. Polyphenols are efficient iron-chelators.
- Conditions
- Dysmetabolic Iron Overload Syndrome, Genetic Hemochromatosis, Iron Absorption, Polyphenols
- Trial name
- POLYFER (NCT03453918)
- Testing
- polyphenols
- Where
- France
- Volunteers
- 41 people
- Sponsor
- University Hospital, Clermont-Ferrand
Obesity, Diabetes Mellitus
Type 2 Diabetes Primary Prevention for At Risk Girls
Purpose: To evaluate two approaches to prevent obesity and type 2 diabetes in young girls. The Need: We are experiencing an epidemic of childhood obesity.
- Conditions
- Obesity, Diabetes Mellitus, Pre Diabetes
- Trial name
- NCT00063674
- Testing
- Nutrition Education, After-school dance class
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diabetes Mellitus, Type 1, Hypoglycemia
The Role of Glucose-Dependent Insulinotropic Polypeptide in the Pathological Glucose Homeostasis Of Type 1 Diabetes
In the present project the investigators will evaluate whether glucagonotropic properties of the gut-derived incretin hormone glucose-dependent insulinotropic polypeptide (GIP) may be utilized as a safeguard against hypoglycemia…
- Trial name
- NCT03734718
- Testing
- GIP
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Steno Diabetes Center Copenhagen
Diabetes Mellitus, Type 2
Representation of Diet in the Management of Type 2 Diabetes in Migrant Patients at CHSD
This observational and monocentric study aims to explore how migrant patients with type 2 diabetes perceive and represent food in the context of their diabetes care.
- Trial name
- NCT06969391
- Where
- France
- Volunteers
- 11 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Type 2 Diabetes
Placebo and Active Comparator Controlled Dose Response Study of Rivoglitazone in Type 2 Diabetes
The purpose of the study is to assess the efficacy response of rivoglitazone HCl compared to pioglitazone HCl on the placebo-corrected change from baseline in HbA1c after 12 weeks of treatment in patients with type 2 diabetes.
- Trial name
- RAISE (NCT00575874)
- Testing
- Rivoglitazone HCl, pioglitazone HCl
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Atherosclerosis, Osteoporosis
Research on Aging Project in Iceland: Second Stage
Background: Researchers are interested in studying the environmental and genetic factors that play a role in health and living conditions as people age. Since 2002, the U.S.
- Conditions
- Atherosclerosis, Osteoporosis, Obesity, Glucose Abnormalities
- Trial name
- NCT01322568
- Where
- Iceland
- Volunteers
- 5,764 people
- Sponsor
- National Institute on Aging (NIA)
Hypertension, Diabete Type 2
Clinical Trial to Evaluate the Efficacy and Safety of Monotherapy Group of HL1113R1 or HL1113R2 Versus HL1113 (Fixed Dose Combination) in Patients With Essential Hypertension and Type II Diabetes Mellitus
This clinical trial is a randomized, active controlled, double blind, parallel, multi center, phase 3 study to evaluate the efficacy and safety of monotherapy group of HL1113R1 or HL1113R2 versus HL1113 (Fixed dose combination)…
- Trial name
- NCT07552389
- Testing
- Test group, Exploratory test group, Control group 1
- Where
- South Korea
- Volunteers
- 228 people
- Sponsor
- Hanlim Pharm. Co., Ltd.
Diabetes Mellitus
An Open Therapeutic Project to Confirm the Efficacy Tolerability and Safety Profile of Lantus in Everyday Medical Practice
The objective of this survey on this registered product is to confirm the efficacy, and safety profile of Lantus in every day medical practice.
- Trial name
- NCT00576368
- Testing
- INSULIN GLARGINE
- Where
- Belgium
- Volunteers
- 4,464 people
- Sponsor
- Sanofi
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