Clinical trials: Metabolic Disorder, Glucose
Type 2 Diabetes Mellitus
Reducing Emergency Department Visits and Improving Glucose Control in Uncontrolled Type 2 Diabetes Using CGM Sensors at Hospital Discharge
Quality measures and cost-reduction methods are a high priority in the United States health care system. This includes the high burden of patients with uncontrolled Type 2 Diabetes.
- Trial name
- NCT04277780
- Testing
- Continuous Glucose Monitoring Sensor, Diabetes Management Instructions
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Albert Einstein Healthcare Network
Diabetes Mellitus, Type 2
A Study to Test the Effectiveness and Safety of MK0893 in Combination With Other Drugs Used to Treat Type 2 Diabetes (0893-015)
This study will test the effectiveness and safety of treatment with MK-0893 in combination with other drugs commonly used to treat type 2 diabetes for a duration up to 13 weeks.
- Trial name
- NCT00631488
- Testing
- MK-0893, Sitagliptin, Metformin
- Volunteers
- 146 people
- Sponsor
- Merck Sharp & Dohme LLC
Type 2 Diabetes
Effect of HBM Based Education on Glycemic Control of Type 2 Diabates Patients
This pre-post-test randomized controlled (parallel group) experimental design study aimed to determine the effect of education based on health belief model and health literacy level of patients with type 2 diabetes on disease…
- Trial name
- NCT04677127
- Testing
- Health Belief Model and Health Literacy Level based Education and Counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Hacettepe University
Diabetes, Diabetes Mellitus
Glycemic Control in Diabetic Hospitalized Patients
With the advanced management of diabetes and new innovative anti-hyperglycemic therapy hyperglycemia remains a culprit factor affecting the outcome of patients admitted to the hospital in general wards.
- Trial name
- NCT04800861
- Where
- Iraq
- Volunteers
- 120 people
- Sponsor
- AlFayhaa General Hospital
Diabetes Mellitus, Type 2
Dose Ranging Study of Albiglutide in Japanese Subjects
This is a randomized, double-blind, placebo-controlled, multicenter, 4-parallel-group, dose ranging study evaluating the dose response, efficacy and safety of subcutaneously injected GSK716155 (albiglutide) in Japanese subjects…
- Trial name
- NCT01098461
- Testing
- albiglutide
- Where
- 30 sites in Japan
- Volunteers
- 215 people
- Sponsor
- GlaxoSmithKline
Type 2 Diabetes Mellitus
Dose Comparisons of Leucine-Metformin Combinations on Blood Glucose Levels In Type 2 Diabetic Patients
The goal of this study is to demonstrate that leucine in combination with a low does of metformin can serve as an adjunct to diet and exercise to improve blood glucose levels in type 2 diabetic subjects.
- Trial name
- NCT02151461
- Testing
- Low Metformin, Metformin, Mid Metformin
- Where
- 9 sites in United States
- Volunteers
- 96 people
- Sponsor
- NuSirt Biopharma
Type 1 Diabetes Mellitus
Protege Extension Trial - Long Term Follow Up Trial for Subjects Who Completed the Protege Study (CP-MGA031-01)
The purpose of this study is to assess the long term safety and efficacy in subjects with Type 1 Diabetes Mellitus who completed the Protege Study (CP-MGA031-01).
- Trial name
- NCT00870818
- Testing
- Blood samples for safety, Patient reported outcome questionnaires, Analysis of T-cell subsets
- Where
- United States
- Volunteers
- 219 people
- Sponsor
- MacroGenics
Pre-diabetes, Obese
Investigation of an Amino Acid Supplement on Glucose Levels in Obese Subjects
This study aims to determine whether the use of Branched-Chain Amino Acids (BCAA's) regulate insulin and glucagon secretion, and whether the supplement has any effect on body weight and body composition.
- Conditions
- Pre-diabetes, Obese, Glucose Intolerance
- Trial name
- NCT03715010
- Testing
- BCAA
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Metabolic Syndrome
Development of Endothelial Biomarkers
The main objective is to develop and validate new endothelial function markers discriminating and reproducible by assessing the ability to reveal changes in endothelial function in response to positive and negative nutritional…
- Trial name
- NUTREND (NCT02006810)
- Testing
- Induction of endothelial function variations
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Diabetes Mellitus
Association Between Uric Acid / High Density Lipoprotein Ratio and Monocyte / High Density Lipoprotein Ratio With Diabetic Complications
Type 2 diabetes mellitus (T2DM) poses a formidable global health challenge, with complications arising in both the microvascular and macrovascular domains as glycemic control worsens.the aim of the study to evaluate uric acid /…
- Trial name
- NCT06754813
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Heart Failure, Diabetes Mellitus
Empagliflozin Versus Placebo on the Rate of Arrhythmic Events in Heart Failure Patients
Empagliflozin treatment in high cardiovascular risk patients has been shown to have a relatively rapid powerful capability in reducing cardiovascular mortality.
- Conditions
- Heart Failure, Diabetes Mellitus, Arrythmia
- Trial name
- ERA-HF (NCT03271879)
- Testing
- Empagliflozin at a dose of 10 mg/day
- Volunteers
- 128 people
- Sponsor
- Rambam Health Care Campus
Obesity, Glucose Homeostasis
Bazedoxifene/Conjugated Estrogens (BZA/CE) Improvement of Metabolism (BIM)
The goal of this pilot clinical study is to perform a randomized placebo-controlled study to assess the beneficial effect of a 3 month-treatment with Bazedoxifene/Conjugated Estrogens (BZA/CE) vs.
- Conditions
- Obesity, Glucose Homeostasis, Postmenopausal Symptoms
- Trial name
- BIM (NCT02237079)
- Testing
- Bazedoxifene/Conjugated Estrogens (BZA/CE)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Tulane University Health Sciences Center
Diabetes Mellitus, Type 2, Penile Diseases
Penile Length Restoration in Men With Diabetes Mellitus, Type II
The objective of the current study is to evaluate the efficacy of a novel penile traction device in restoring lost penile length in men with type 2 diabetes.
- Trial name
- NCT03756688
- Testing
- RestoreX PTT - 6 months, RestoreX PTT - 3 months
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Mayo Clinic
Diabetes Mellitus Type 2 in Obese
DMBSS-A Randomized Trial of Different Laparoscopic Gastric Bypass Surgery in Patients With Obesity-related T2DM
The investigators would like to conduct a randomized clinical trial to compare the efficacy of diabetes treatment between different gastric bypass procedures involving type 2 diabetics patients with BMI from 27.5 to 35 kg/m2
- Trial name
- DMBSS (NCT01989988)
- Testing
- LMGB, LRYGB, SADJB
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Min-Sheng General Hospital
Diabetes
Together on Diabetes Study: Evaluation of a Pilot Diabetes Prevention and Management Program for American Indian Youth
The objective of the Together on Diabetes study is to test the efficacy of a pilot intervention to improve the prevention and management of type 2 diabetes among American Indian youth.
- Trial name
- NCT01910727
- Testing
- Together on Diabetes-Hopkins
- Where
- United States
- Volunteers
- 506 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Type 2 Diabetes Mellitus
A Study to Evaluate the Effect of Ranolazine on Postprandial Glucagon in Subjects With Type 2 Diabetes.
To explore the mechanism of action of ranolazine as a potential treatment for type 2 diabetes mellitus (T2DM).
- Trial name
- NCT01843127
- Testing
- Ranolazine, Exenatide
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Gilead Sciences
Type 1 Diabetes
Team Clinic: Virtual Expansion of an Innovative Multi-Disciplinary Care Model for Adolescents and Young Adults With Type 1 Diabetes
Team Clinic is a new care approach for middle and high school aged patients living with T1D and their families. This study is a 15-month randomized control trial (RCT) that consists of Virtual Team Clinic Care appointments…
- Trial name
- NCT04190368
- Testing
- Team Clinic Care, Standard Care
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Children's Hospital Los Angeles
Type 2 Diabetes Mellitus
Efficacy and Tolerability of Saxagliptin add-on Compared to Uptitration of Metformin in Patients With Type 2 Diabetes
The study will evaluate the efficacy and tolerability of saxagliptin compared to uptitration of metformin in patients with type 2 diabetes who have inadequate glycaemic control on a submaximal dose of metformin.
- Trial name
- PROMPT (NCT01006590)
- Testing
- Saxagliptin, Metformin
- Where
- 51 sites in Belgium, France and 5 more
- Volunteers
- 286 people
- Sponsor
- AstraZeneca
Coronary Heart Disease, Diabetes
OPtimized Stenting Using Intravascular Ultrasound(IVUS) in Long lEsion: Rationale for Simplified criteriA
Rationale IVUS has shown to be efficient for bare metal stent deployment, but has not been specifically studied for Drug Eluting Stents.
- Conditions
- Coronary Heart Disease, Diabetes, Vascular Lesions, Chronic Total Occlusion of Coronary Artery
- Trial name
- OPERA (NCT01861860)
- Testing
- TAXUS™ Element long stent
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Cushing Syndrome
Long-term Beneficial Metabolic Effects of Adrenalectomy in Subclinical Cushing's Syndrome of Adrenal Incidentaloma
Objective: To determine the metabolic effects of the adrenalectomy in subclinical Cushing's syndrome of adrenal incidentaloma. Methods: 234 subclinical cushing syndrome and adrenal incidentaloma will be randomly assigned into two…
- Trial name
- NCT01382420
- Testing
- surgery
- Where
- South Korea
- Volunteers
- 234 people
- Sponsor
- Samsung Medical Center
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