Clinical trials: Metabolic Disorder, Glucose
Liver Cirrhosis
Cirrhosis, Effects of TRAnsplantation and Diabetes
This observational study is aimed at assessing insulin secretion and sensitivity by the use of a mathematical modeling from oral glucose tolerance test in subjects with liver cirrhosis undergoing orthotopic liver transplantation…
- Trial name
- CETRA (NCT02038517)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Diabetes Mellitus, Type 2
Regulatory Request NIS in Korea
To monitor the safety profile and effectiveness of JARDIANCE DUO® in Korean patients with type 2 diabetes mellitus in a routine clinical practice setting
- Trial name
- NCT03642717
- Testing
- JARDIANCE DUO®
- Where
- 20 sites in South Korea
- Volunteers
- 658 people
- Sponsor
- Boehringer Ingelheim
Preeclampsia, Gestational Diabetes
Exercise and Pregnancy: Randomized Clinical Trial
The effects of physical exercise on pregnancy remain to be elucidated. A randomized controlled trial will be conducted to study the impact of exercise on maternal and perinatal outcomes.
- Trial name
- NCT00641550
- Testing
- Physical exercise
- Where
- 2 sites in Brazil
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual da Paraiba
Pre Diabetes, Exercise
The Effect of Exercise and Metformin on Carotid Intima-media Thickness in Patients With Prediabetes
The aim of this study is to evaluate whether there is a change in carotid intima media thickness with the application of guide-based exercise programs in individuals with prediabetes, and to evaluate whether there is a difference…
- Conditions
- Pre Diabetes, Exercise, Metformin, Atherosclerosis
- Trial name
- NCT05052918
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Gestational Diabetes Mellitus
Glyburide and Metformin for the Treatment of Gestational Diabetes Mellitus. Systematic Review
Since the publication in the New England Journal of Medicine (NEJM) in 2000 of the Langer's trial comparing glyburide vs insulin in the treatment of gestational diabetes mellitus (GDM), additional studies of oral agents for the…
- Trial name
- NCT01998113
- Testing
- Glyburide vs Insulin trials, Metformin vs Insulin trials, Metformin vs Glyburide trials
- Where
- Spain
- Volunteers
- 2,509 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Type 1 Diabetes
Randomized Study of Real-Time Continuous Glucose Monitors (RT-CGM) in the Management of Type 1 Diabetes
Subjects with intensively-treated type 1 diabetes and glycated hemoglobin (HbA1c) 7.0%-10.0% in 3 age groups (>25, 15-24, 8-14) will be randomized to a continuous glucose monitoring (CGM) group or control group.
- Trial name
- NCT00406133
- Testing
- Continuous glucose monitor
- Where
- 11 sites in United States
- Volunteers
- 451 people
- Sponsor
- Jaeb Center for Health Research
Adverse Pregnancy Outcomes, Cardiovascular Diseases
A Study to Lower Blood Pressure One Year After Childbirth in Women Who Had Preeclampsia
GESTA-SCORE is a prospective, randomized clinical trial designed to evaluate whether an early, personalized cardiovascular prevention strategy can achieve a clinically meaningful 6 mmHg reduction in systolic blood pressure at one…
- Trial name
- GESTA-SCORE (NCT06798649)
- Testing
- The intervention in the GESTA-SCORE study involves providing detailed feedback from vascular imaging to women who have experienced adverse pregnancy outcomes (APOs).
- Volunteers
- 150 people
- Sponsor
- Maternal-Infantil Vall d´Hebron Hospital
Periodontitis, Adult, Metabolic Syndrome
Genetic Variants and Oxidative Stress as Links Between Periodontitis and Metabolic Syndrome
The aim of this study is to investigate the systemic impact of periodontitis in patients with Metabolic Syndrome, by assessing measures of sub-clinical atherosclerosis and cardiovascular risk, microbial factors and host genetic…
- Trial name
- NCT03297749
- Testing
- Observational study (no intervention)
- Where
- 2 sites in Italy, United Kingdom
- Volunteers
- 102 people
- Sponsor
- University College, London
Diabetes Mellitus, Type 2
The Effects of Self-management Education Based on Theory of Planned Behavior on Patients With Type 2 Diabetes
The aims of the study are as follows: To improve self-management intention and behavior of patients with type 2 diabetes (T2 DM).
- Trial name
- NCT02594748
- Testing
- Self-management education, Routine care
- Where
- China
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of Turku
Diet Habit, Type I Diabetes
How Type I Diabetes Responds to Different Diets (Normoglucidic or Ketogenic) During Physical Activity at Altitude
To date, no study has shown the effects of diets (normoglucidic or ketogenic) on type I diabetes during physical activity (hiking, ski touring) at altitude.
- Conditions
- Diet Habit, Type I Diabetes, Activity, Motor, Control
- Trial name
- DIAREAL (NCT06242548)
- Testing
- physical activity outings in the mountains at a level already practised by the subjects, while maintaining their usual diet (normoglucidic or ketogenic)
- Where
- France
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Metropole Savoie
Gestational Diabetes, Pregnancy
Integrating the Use of Calibration-Free Continuous Monitoring for Pregnancy Glucose Profiling: I-Profile Study
This study aims to test the following hypotheses in a longitudinal, observational study in pregnant women who will be randomized to received either a Blinded or Unblinded CGM sensor and followed-up 6-12 weeks after delivery: 1.
- Trial name
- I-Profile (NCT05123248)
- Testing
- Blinded Group, Unblinded group
- Where
- Singapore
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Surgical Site Infections, Stress Hyperglycemia
Perioperative Glucose Monitoring and Treatment to Reduce Risk of Surgical Site Infections and Complications
This study is to determine if glucose monitoring and treatment in surgical procedures over 2 hours help to decrease the surgical site infection risk and reduce postoperative complications.
- Trial name
- POGM (NCT06765655)
- Testing
- Insulin Lispro Injection, glucose testing
- Where
- United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- St. Peter's Hospital, Albany, NY
Percutaneous Coronary Intervention, Heart Failure
REgiStry-based Cardiovascular qUality improvEment Research
The goal of this registry-based observational study is to establish a comprehensive management plan, which focus on medical therapy, cardiac rehabilitation and active post-market surveillance of medical devices, in patients with…
- Conditions
- Percutaneous Coronary Intervention, Heart Failure, Cardiometabolic Syndrome, Structural Heart Abnormality
- Trial name
- RESCUER (NCT06137885)
- Testing
- Cardiac rehabilitation, Active post-market surveillance of devices, Multi-omics approach to precision medicine
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Peking University Third Hospital
Diabetes, Diabetes Mellitus, Type 1
Observational Study of Patients Using NovoMix® 30 or Levemir® for Treatment of Type 1 or Type 2 Diabetes
This trial is conducted in Europe. The aim of this observational study is to evaluate the glycaemic control in patients with type 1 or 2 diabetes using NovoMix® 30 or Levemir® under normal clinical practice conditions.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT00671008
- Testing
- biphasic insulin aspart 30, insulin detemir
- Where
- Bosnia and Herzegovina
- Volunteers
- 400 people
- Sponsor
- Novo Nordisk A/S
Type 1 Diabetes
Cord Blood Plus Vitamin D and Omega 3s in T1D
In this pilot study the investigators are trying to see if a single intravenous infusion of autologous (self) cord blood cells followed by 1 year of daily vitamin D and omega 3 fatty acid supplementation can preserve beta cell…
- Trial name
- NCT00873925
- Testing
- Autologous UCB, Omega 3 FA, Vitamin D
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Florida
Type 1 Diabetes
Effect of Heatwave Over Glycemic Control in Patients With T1D
Observational study about effect of the greatest Spanish heatwave over glycemic contro in adult patients with type 1 Diabetes mellitus.
- Trial name
- NCT05646017
- Testing
- Intermittenly scanned continuous glucose monitoring
- Where
- 9 sites in Spain
- Volunteers
- 2,701 people
- Sponsor
- Castilla-La Mancha Health Service
Type 2 Diabetes
Cocoa Polyphenols and Postprandial Metabolism in Type 2 Diabetes
This study aims to investigate the postprandial effects of cocoa supplementation in glucose and lipids, and surrogate markers of atherosclerosis in patients with type 2 diabetes.
- Trial name
- NCT01886989
- Testing
- Cocoa polyphenols
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Arpita Basu
Transgenderism, Insulin Sensitivity/Resistance
Puberty Suppression and Cardiometabolic Health
This observational study will evaluate the effect of puberty suppression on insulin sensitivity, metabolic rate and vascular health among transgender female youth at baseline and 6 months after initiation of a gondoatropin…
- Conditions
- Transgenderism, Insulin Sensitivity/Resistance, Endothelial Dysfunction, Vascular Stiffness
- Trial name
- NCT04482374
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Colorado, Denver
Diabetic Nephropathy
Benfotiamine in Diabetic Nephropathy
The purpose of this study is to investigate the effect of benfotiamine supplementation in patients with diabetic nephropathy, and to determine whether it will slow down the progression to end-stage renal disease (ESRD).
- Trial name
- Benfo (NCT00565318)
- Testing
- Benfotiamine
- Where
- Netherlands
- Volunteers
- 86 people
- Sponsor
- University Medical Center Groningen
Diabetes
Case-Control Study of Inflammatory Breast Cancer in North Africa
Background: Inflammatory breast cancer (IBC) is a rare, poorly understood and particularly aggressive form of breast cancer. Three characteristics of IBC tumors their rapid progression, their extensive formation of new blood…
- Trial name
- NCT00793390
- Where
- 6 sites in Egypt, Morocco and 1 more
- Volunteers
- 815 people
- Sponsor
- National Cancer Institute (NCI)
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