Clinical trials: Metabolic Disorder, Glucose
Type 2 Diabetes Mellitus (T2DM)
The Effect of Individualized Nursing Interventions on Glycemic Variability and Self-Management in Type 2 Diabetes
Type 2 diabetes is a chronic disease with an increasing prevalence worldwide and in our country. In managing type 2 diabetes, the primary goal in the nursing process is to ensure blood glucose stability.
- Trial name
- NCT06973395
- Testing
- Nursing interventions, education, and follow-up will be provided to Type 2 diabetes patients for blood glucose variability.
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Ataturk University
Diabetes, Diabetes Mellitus, Type 2
Efficacy of Biphasic Insulin Aspart 30 in Type 2 Diabetics Failing on OADs
This trial is conducted in the United States of America (USA). The aim of this trial is to investigate the effectiveness of biphasic insulin aspart 30 in type 2 diabetics not achieving blood sugar levels when treated with oral…
- Trial name
- NCT00791895
- Testing
- biphasic insulin aspart 30
- Where
- 15 sites in United States
- Volunteers
- 102 people
- Sponsor
- Novo Nordisk A/S
Obesity, Diabetes Type 2
Metabolic and Hormonal Effects of 5:2 Intermittent Fasting
The aim of the present study is to investigate in subjects with and without type 2 diabetes the effect of calorie restriction (CR) according to the 5:2 method for 6 months (every week two days caloric fasting with 500 calories…
- Trial name
- NCT02450097
- Testing
- Caloric restriction
- Where
- Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Type 2 Diabetes
Effect of Breakfast or Omission of Breakfast in T2D
The investigators will explore the effect of omission of breakfast on postprandial hyperglycemia and insulin and intact GLP-1 response after subsequent meals in type 2 diabetic patients
- Trial name
- OB-B (NCT01571310)
- Testing
- Omitted Breakfast, Breakfast
- Where
- 2 sites in Israel, Venezuela
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Gestational Diabetes
Does Soluble Fiber Supplementation Result in Lower Postprandial Blood Glucose in Women With Gestational Diabetes Compared With no Supplementation After a Standardized Breakfast?
The objective of this study is to investigate the effect of supplementation of 10g soluble fiber from guar on postprandial blood glucose levels in women with gestational diabetes after consumption of a standardized meal compared…
- Trial name
- DiFiGDM (NCT05925010)
- Testing
- Supplementation with soluble fibre from guar (Optifibre©)
- Where
- Austria
- Volunteers
- 67 people
- Sponsor
- Medical University of Graz
Diabetes, Diabetes Mellitus, Type 1
A Trial Comparing the Safety and Efficacy of Insulin Degludec and Insulin Glargine, Both With Insulin Aspart as Mealtime Insulin in Subjects With Type 1 Diabetes
This trial is conducted in Europe and the United States of America (USA). The aim of the trial is to compare the safety and efficacy of insulin degludec (IDeg) and insulin glargine (IGlar), both with insulin aspart (IAsp) as…
- Trial name
- SWITCH 1 (NCT02034513)
- Testing
- insulin degludec, insulin glargine, insulin aspart
- Where
- 99 sites in United States, Poland and 1 more
- Volunteers
- 501 people
- Sponsor
- Novo Nordisk A/S
Type2 Diabetes Mellitus
IRAPe, Irisin and IL-34 in Patients With Type 2 Diabetes
Aim: This study aimed to evaluate the role of extracellular part of insulin regulated aminopeptidase (IRAPe), IL-34, Irisin, and Visfatin in the development of insulin resistance in patients with type 2 diabetes mellitus.
- Trial name
- NCT04107259
- Testing
- Blood sample
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Damanhour University
Metabolic Syndrome, Diabetes
Post-prandial Glycaemic Controlling Effects of BSG in Singapore Adults With Metabolic Syndrome
The purpose of this study is to assess the glycaemic controlling effects of BSG and bio-transformed BSG-containing biscuits in Singapore adults with MetS.
- Conditions
- Metabolic Syndrome, Diabetes, Diet Modification
- Trial name
- NCT05421780
- Testing
- autoclaved BSG-containing biscuits, bio-transformed BSG-containing biscuits, control biscuits
- Where
- Singapore
- Volunteers
- 16 people
- Sponsor
- National University of Singapore
Diabetes Mellitus Type 2
A Study of The Effect of Aleglitazar on Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin
This single-center, randomized, double-blind, placebo-controlled study will evaluate the effect of aleglitazar on insulin sensitivity in patients with type 2 diabetes mellitus who are inadequately controlled on metformin…
- Trial name
- NCT01729403
- Testing
- aleglitazar, metformin
- Where
- Germany
- Volunteers
- 57 people
- Sponsor
- Hoffmann-La Roche
Osteoporosis, Postmenopausal, Type 2 Diabetes
Use of Ibandronate in Diabetic Patients
The purpose of this study is to examine whether monthly oral administration of ibandronate to postmenopausal osteoporosis patients with type 2 diabetes differs in safety and efficacy compared to patients without diabetes.
- Trial name
- NCT05266261
- Testing
- Ibandronate Oral Tablet
- Where
- South Korea
- Volunteers
- 121 people
- Sponsor
- Yeouido St. Mary's Hospital
Retinal Ischemia, Diabetes Complications
Changes in the Diameter of Retinal Vessels After Remote Ischemic Conditioning in Patients With Type 1 Diabetes
Remote ischemic conditioning (RIC) is a therapeutic strategy for protecting organs or tissue against the detrimental effects of acute ischemia-reperfusion injury.
- Conditions
- Retinal Ischemia, Diabetes Complications, Ischemia, Diabetes Mellitus, Type 1
- Trial name
- NCT03906383
- Testing
- Remote Ischemic Conditioning
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- University of Aarhus
Diabetes, Diabetic Macular Oedema
Trial of Switching Between Intravitreal Bevacizumab (Avastin®)& Intravitreal Dexamethasone (Ozurdex™) for Persistent Diabetic Macular Oedema
The specific aim of the study is to test the following hypothesis: That switching between treatments from bevacizumab to Ozurdex or vice versa in eyes with diabetic macular oedema with no or incomplete response from one therapy…
- Conditions
- Diabetes, Diabetic Macular Oedema, Diabetic Macular Edema, Diabetic Retinopathy
- Trial name
- SwitchDMO (NCT01787669)
- Testing
- Avastin (Bevacizumab), Ozurdex (dexamethasone)
- Where
- 3 sites in Australia
- Volunteers
- 19 people
- Sponsor
- University of Sydney
Diabetic Foot Ulcer (DFU), Diabetic Foot Disease
Predictive Analysis of Diabetic Foot Ulcer
The purpose of this study was to retrospectively analyze the wound condition, limb condition, ulcer recurrence and cardiovascular and mortality of patients with diabetic foot ulcer after admission to our hospital from 2009 to…
- Conditions
- Diabetic Foot Ulcer (DFU), Diabetic Foot Disease, Diabetes
- Trial name
- NCT06768554
- Testing
- Level of blood sugar control (e.g., hemoglobin A1C), severity of infection, blood supply status, and other complications (e.g., peripheral neuropathy)
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Coronary Heart Disease (CHD), Diabetes (DM)
A Prospective Multicenter Clinical Study： IntracOronary neaR-Infrared Spectroscopy and OptIcal Coherence Tomography for Evaluating Coronary vulNerable Plaque in Patients With diabeTes
To evaluate the correlation between maxLCBI4mm/FCTmin(a new index of lipid plaque based on NIRS-OCT technology) and fiber cap thickness , and the prognosis of patients, providing a new quantitative index for early, accurate and…
- Trial name
- NCT06649305
- Where
- China
- Volunteers
- 1,516 people
- Sponsor
- Shanghai Zhongshan Hospital
Diabetes Mellitus, Type 1
Mindfulness-based Arabic Guided Self-help for Parents of Children With Type 1 Diabetes
Kuwait ranks as the third country worldwide for the incidence of type 1 diabetes (T1D) with an incidence of 37.10 per 100,000 children.
- Trial name
- NCT03358394
- Testing
- A human-interventional study
- Where
- Kuwait
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- SHAHAH ALTAMMAR
Type 2 Diabetes
SIT LESS 2: Effect of Sitting Less on Glucose Regulation in People With Diabetes Mellitus Type 2
Introduction: Changes in lifestyle are responsible for an important part of the type 2 diabetes epidemic of the last decennia. Current guidelines for physical activity focus mainly on high energy expenditure advising 30 minutes…
- Trial name
- SIT LESS 2 (NCT02371239)
- Testing
- Physical activity intervention
- Where
- Netherlands
- Volunteers
- 19 people
- Sponsor
- Maastricht University Medical Center
Type 1 Diabetes Mellitus
Do Sulphonylureas Preserve Cortical Function During Hypoglycaemia?
To see if using medication called sulphonylureas can help improve symptoms which patients rely on to recognise low blood glucose levels ( hypoglycaemia) and also to see if they can reduce the slowing down in brain function which…
- Trial name
- NCT00472875
- Testing
- Glibenclamide
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- King's College Hospital NHS Trust
Pressure Ulcer, Foot Ulcer, Diabetic
Use of Santyl Within an Accountable Care Organization
This study is designed to assess the comparative effectiveness of SANTYL® versus standard of care in the treatment of pressure ulcers and diabetic foot ulcers within the continuum of care of an ACO.
- Trial name
- NCT02716519
- Testing
- Santyl, Standard Care
- Where
- United States
- Sponsor
- Smith & Nephew, Inc.
Diabetes (DM), Critical Illness
Identifying Diabetes and Impaired Glucose Tolerance in ICU Patients
In the Netherlands, patients admitted to the ICU are classified as having diabetes based on whether their medical records indicate glucose management medication use (Dutch National Intensive Care Evaluation (NICE) Registry).
- Trial name
- DISCOVER (NCT07261865)
- Where
- 2 sites in Netherlands
- Volunteers
- 4,198 people
- Sponsor
- University Medical Center Groningen
Diabetes, Diabetes Mellitus, Type 1
First Research Study to Compare a Possible New Medicine NNC9204-1513 to the Medicine Glucagon, in Healthy People.
The study is comparing the new medicine NNC9204-1513 with a standard therapy of glucagon (GlucaGen®). This is the first time NNC9204-1513 is given to humans.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT03444467
- Testing
- NNC9204-1513, Glucagon
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
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