Clinical trials: Metabolic Disorder, Glucose
Diabetes, Diabetes Mellitus, Type 2
A Trial Investigating the Effects of Semaglutide on ß-cell Function in Subjects With Type 2 Diabetes
This trial is conducted in Europe. The aim of the trial is to investigate the effects of semaglutide on ß-cell function in subjects with type 2 diabetes.
- Trial name
- NCT02212067
- Testing
- semaglutide
- Where
- Germany
- Volunteers
- 87 people
- Sponsor
- Novo Nordisk A/S
Type 1 Diabetes
Obesity Treatment to Improve Diabetes
As the obesity pandemic continues unabated, one can expect to see an increase in the prevalence of TID/T2D and associated CKD. As a result, death will rise, preceded by an increase in kidney failure, requiring dialysis and renal…
- Trial name
- OTID (NCT05390307)
- Testing
- Liraglutide / Semaglutide, Dapagliflozin, Liraglutide or Semaglutide / Dapagliflozin
- Where
- Kuwait
- Volunteers
- 60 people
- Sponsor
- Dasman Diabetes Institute
Metabolic Syndrome
Evaluating the Tolerability and Effects of Berberine on Major Metabolic Biomarkers: A Pilot Study
Berberine is a dietary supplement that comes from the roots, stems, and bark of various plants and has been used for centuries in traditional Chinese medicine.
- Trial name
- NCT03976336
- Testing
- Berberine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Kansas Medical Center
Obesity and Overweight, Pre-diabetic
Targeted Precision Nutrition Strategy To Prevent Chronic Metabolic Diseases
Nutrition is very important to keep blood sugar levels balanced. If blood sugar levels are too high, it can lead to diseases such as cardiovascular disease and type 2 diabetes (T2DM).
- Conditions
- Obesity and Overweight, Pre-diabetic, Type 2 Diabetes Mellitus (T2DM)
- Trial name
- PRECINUT (NCT06923644)
- Testing
- Optimal Metabotype-specific diet, Sub-optimal diet
- Where
- 2 sites in Netherlands
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Diabetes, Diabetic Kidney Disease
Effect of Acute Hypoxia on Renal Hemodynamic in Healthy Volunteers, Patients With Diabetes and Patients With Diabetes and Kidney Disease
Diabetes mellitus is a non-transmissible disease whose incidence is growing worldwide . This pathology is defined by a chronic hyperglycaemia linked to a deficiency of either insulin secretion or its action or both.
- Conditions
- Diabetes, Diabetic Kidney Disease, Hypoxia, Healthy Volunteer
- Trial name
- DIAKIPOX (NCT06846034)
- Testing
- Hypoxia administration study group, Renal clairance study
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Heart Failure, Type 2 Diabetes
Optimizing In-hospital Use of Evidence-based Therapies for Patients With Cardio-Renal-Metabolic Disease
This study will be a prospective randomized implementation trial for patients hospitalized with heart failure, chronic kidney disease, and/or type 2 diabetes mellitus within Duke University Medical Center.
- Conditions
- Heart Failure, Type 2 Diabetes, Chronic Kidney Diseases
- Trial name
- IMPLEMENT-CRM (NCT05781334)
- Testing
- Virtual Consult Intervention
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Duke University
Vitamin D Deficiency, Metabolic Syndrome
Bioavailability and Biological Effects of Vitamin D2 Contained in Mushroom
The purpose of this study is to compare the safety and efficacy of two different amounts of vitamin D2 (600 or 4000 International Units/day) provided by mushrooms added to one of the daily meals versus same doses of vitamin D3…
- Conditions
- Vitamin D Deficiency, Metabolic Syndrome, Prediabetes
- Trial name
- NCT01488734
- Testing
- Mushroom with 600 IU vitamin D2, Mushroom with 4000 IU Vitamin D2, 600 IU Vitamin D3 and untreated mushroom
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Body Weight, Obesity
Meta-analysis of the Nordic Dietary Pattern on Cardiometabolic Risk and Cardiovascular Outcomes
The Nordic Diet is a dietary pattern rich in traditional Nordic foods, including berries, grains, and fatty fish common in northern Europe.
- Conditions
- Body Weight, Obesity, Overweight and Obesity, Obesity, Abdominal
- Trial name
- NCT04094194
- Testing
- Nordic diet
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Type 2 Diabetes Mellitus
Effects of Gut Peptides on Bone Remodeling. KS-4-Diabetes-19
Both GLP-2 and GIP reduce the bone resorption (measured as CTX) in healthy persons. In this study, we will investigate wether GLP-2 and GIP is reducing CTX in persons with type 2 diabetes.
- Trial name
- NCT03867656
- Testing
- GLP-2, GIP
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Diabetes, Diabetes Mellitus, Type 2
Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes
This trial is conducted globally (the United States of America excepted). This trial is designed to show the effect of treatment with liraglutide when added to existing glimepiride therapy and to compare this to both glimepiride…
- Trial name
- LEAD-1 (NCT00318422)
- Testing
- liraglutide, rosiglitazone, glimepiride
- Where
- 127 sites in Argentina, Australia and 21 more
- Volunteers
- 1,041 people
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes, Obesity
Preventing Diabetes in Latino Families
Purpose: This study will test the efficacy of a family-focused lifestyle intervention for reducing type 2 diabetes (T2D) risk factors and increasing Quality of Life (QoL) among high-risk Latino families.
- Conditions
- Type 2 Diabetes, Obesity, Pediatric Obesity
- Trial name
- NCT05228522
- Testing
- Lifestyle Intervention
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Diabetes Mellitus, Type 2
Jikei Optimal Insulin Therapy in Type 2 Diabetes
The purpose of this study is to compare whether there is the difference in the effect of insulin therapy by the number of times of insulin injection.
- Trial name
- NCT00348231
- Testing
- dual-action insulin analog
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- Jikei University School of Medicine
Diabetes Mellitus, Type 2
A Research Study, Looking at How Tresiba® Works in People With Type 2 Diabetes in Local Clinical Practice in China
The purpose of the study is to collect information on how Tresiba® works in patients with type 2 diabetes in China. The study will be based on data already recorded in participants' medical records and no new tests or procedures…
- Trial name
- CN-TREAT (NCT04227431)
- Testing
- Insulin degludec
- Where
- 56 sites in China
- Volunteers
- 938 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus, Type 2
Clinical Trial on Diabetes Expert Patients Programme
The purpose of this study is to determine whether participation in a diabetes expert patients programme course is effective in self-management of a chronic condition such as diabetes, if it reduces Haemoglobin A glycosylated…
- Trial name
- EPPD-ICS (NCT01898702)
- Testing
- Diabetes expert patients programme
- Where
- 3 sites in Spain
- Volunteers
- 500 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Type 2 Diabetes Mellitus, Walking
Cadence and Intensity in Adults With Type 2 Diabetes
The purpose of this study is to measure and link cadence (number of steps taken in a minute) to intensity of physical activity (e.g., low-intensity, moderate intensity, vigorous-intensity) in adults (40- 65 years-old) with type 2…
- Trial name
- CADENCE-T2DM (NCT03940937)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Massachusetts, Amherst
Gestational Diabetes
Individualized Early Diagnosis and Treatment System of Gestational Diabetes Mellitus (GDM) Based on New Continuous Glucose Monitoring (CGM) Technology
Gestational diabetes mellitus (GDM), as the most common metabolic complication of pregnancy, poses a serious threat to maternal and fetal metabolic health.
- Trial name
- NCT07276945
- Testing
- No interventions
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Healthy, Type 2 Diabetes Mellitus
Type 2 Diabetes Glucose Biomarker Study With a Continuous Glucose Monitoring System
Current gold standard methodologies for diagnosing type 2 diabetes (T2D) or prediabetes can be unreliable and inaccurate, and require the need for multiple different tests for comparison.
- Trial name
- NCT04529239
- Testing
- Abbott Freestyle Libre Pro
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Klick Inc.
Diabetes, Diabetes Mellitus
Biolinq External Interferent Protocol
The primary objective of the study is to evaluate the interference effect of acetaminophen (APAP) on the Biolinq MicroArray Intradermal Continuous Glucose Biowearable System during a single in-clinic day on Day 3 of the sensor…
- Trial name
- NCT06560177
- Testing
- The Biolinq MicroArray Intradermal Continuous Glucose Biowearable System
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Biolinq Inc.
Diabetes, Type 1 Diabetes
Behavioral Economic Incentives to Improve Glycemic Control Among Adolescents and Young Adults
In this study the investigators will compare a novel approach using daily financial incentives and a tiered sponsor network to motivate adolescents and young adults with type 1 diabetes to improve glycemic control.
- Trial name
- NCT02568501
- Testing
- Daily feedback, Financial incentive
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Foot Ulcer, Diabetes
Safety and Efficacy Study of an Interactive Wound Dressing (KC002) for the Treatment of Diabetic Foot Ulcers
The objective of this study is to determine the safety and effectiveness of a device (the KC-002 interactive wound dressing) in the promotion of healing in diabetic foot ulcers as compared with a conventional wound therapy…
- Trial name
- KC-002PT (NCT00330265)
- Testing
- KC-002, Conventional Wound Therapy
- Where
- 21 sites in United States
- Volunteers
- 300 people
- Sponsor
- KeraCure
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