Clinical trials: Metabolic Disorders
Diabetes Mellitus
Lifestyle in Turkish-Background Diabetics
Background: Life-style interventions are indicated in patients with metabolic syndrome and/or type 2 diabetes. However, cultural differences are substantial confounders to not only compliance, but also whether or not the…
- Trial name
- NCT03281616
- Testing
- Diet
- Volunteers
- 110 people
- Sponsor
- Charite University, Berlin, Germany
Obesity
Effect of Olvanil Supplementation on Clinical, Biochemical and Anthropometric Parameters in Obese Adults
Capsaicinoids are defined as alkaloid compounds of the Capsicum genus, they are characterised by the pungent flavor of chili. About the Capsicum genus, there are more than 20 known compounds, including dihydrocapsaicin…
- Trial name
- NCT05857306
- Testing
- Olvanil
- Where
- 2 sites in Mexico
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Guadalajara
Obesity, Sarcopenia
Biological Effects of Weight Loss In Older, Obese Women
Obesity and sedentary lifestyle are associated with physical impairments and biological changes in older adults. Weight loss combined with exercise may reduce inflammation and may improve physical functioning in older adults who…
- Trial name
- WL+E (NCT01032733)
- Testing
- Lifestyle Counseling, Educational Control
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Florida
Metabolic Dysfunction-Associated Steatotic Liver Disease
Study of Metabolic Dysfunction-Associated Steatotic Liver Disease Among Sohag University Employees
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the latest term for steatotic liver disease associated with metabolic syndrome.
- Trial name
- NCT06536933
- Testing
- Abdominal Ultrasound
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Type 2 Diabetes, Hypercholesterolemia
The Potential Effects and Mechanisms of Flax Lignans on Type 2 Diabetes Mellitus
The purpose of the study is to improving the lipid profile and glucose control in type 2 diabetic patients with supplementation of flax lignans.
- Trial name
- NCT00363233
- Testing
- flax lignans
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chinese Academy of Sciences
Iron Metabolism Disorders
Iron Status in Women of Reproductive Age Reproductive Age
Analyzed iron status, HFE mutations and ethnicity for women in five primary care centers in the United States and Canada using de-identified data from the HEIRS study.
- Trial name
- NCT03276247
- Testing
- observation
- Where
- United States
- Volunteers
- 22,042 people
- Sponsor
- Victor Gordeuk
Healthy
Various Serving Sizes of Lentils on Blood Glucose and Insulin
The purpose of this study is to assess the effects of consuming either 1/2 or 1/4 cup servings of lentils on post-prandial blood glucose and insulin as compared to 4 types of starchy foods (corn, macaroni, white potato, white…
- Trial name
- NCT02940158
- Testing
- 1/4 cup- Small red lentil, 1/4 cup- Small green lentil, 1/4 cup- corn
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Obesity, Weight Loss
Endoscopic Bariatric Therapies (EBTs): A Retrospective and Prospective Multicenter Registry
The purpose of this registry study is to collect data through medical chart review and in patient visits on the efficacy and safety of various Endoscopic Bariatric therapies (EBTs).
- Conditions
- Obesity, Weight Loss, Gastro Esophageal Reflux, Bariatric Surgery Candidate
- Trial name
- EBT (NCT04494048)
- Testing
- Endoscopic Bariatric Therapies
- Where
- United States
- Volunteers
- 9,999 people
- Sponsor
- Weill Medical College of Cornell University
PreDiabetes, Type2diabetes
(DDS) in India: a Screening Tool to Identify Prediabetes and Undiagnosed Type 2 Diabetes in Dental Settings
This study is conducted to evaluate validity of Diabetes Risk Assessment in Dentistry Score (DDS) in Indian population as a screening tool to identify patients with prediabetes and undiagnosed type 2 diabetes in dental setting.
- Conditions
- PreDiabetes, Type2diabetes, Periodontitis
- Trial name
- NCT06453278
- Where
- India
- Volunteers
- 1,746 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Chronic Wounds, Diabetes
FGF-1 for Topical Administration for the Treatment of Diabetic or Venous Stasis Ulcers
FGF-1 is being used for the treatment of patients with diabetic or venous stasis ulcers. Procedure includes topical administration of FGF-1 or placebo and evaluation of safety, pharmacokinetics, and wound improvement.
- Conditions
- Chronic Wounds, Diabetes, Venous Stasis Ulcers
- Trial name
- NCT00425178
- Testing
- FGF-1
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Venturis Therapeutics, Inc.
Gestational Diabetes
Metformin Versus Insulin in Gestational Diabetes
Gestational diabetes is traditionally treated with insulin. Metformin is a peroral drug used worldwide in the treatment of type 2 diabetes and also in a few studies on patients with gestational diabetes.
- Trial name
- NCT01240785
- Testing
- metformin, insulin
- Volunteers
- 221 people
- Sponsor
- Turku University Hospital
Diabetes
Natural Language Processing and Quality Assessment in Primary Care
The investigators propose to use a Natural Language Processing System (NLP) to provide an initial baseline report for primary care patients at risk for diabetes and cardiovascular complications that will include: a) evidence of…
- Trial name
- NCT01023243
- Testing
- Brochure: Care of the Feet for Those at Risk, Quality Survey: foot exam, tobacco and aspirin use
- Where
- United States
- Volunteers
- 389 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Hypertension, Dyslipidemias
Communicating Health Information and Improving Coordination With Primary Care
Survivors of childhood cancer are known to be at higher risk of developing premature, serious cardiovascular disease compared with the general population.
- Conditions
- Hypertension, Dyslipidemias, Diabetes, Childhood Cancer
- Trial name
- CHIIP (NCT03104543)
- Testing
- Education, Test results only
- Where
- United States
- Volunteers
- 347 people
- Sponsor
- Fred Hutchinson Cancer Center
Calorie Deficiency, Fasting
Effects of Calorie Restriction and Cold Stimuli on Health-related Indicators, Cognitive and Motor Functions
The goal of this clinical trial was to identify if duration of acute calorie restriction (CR)/fasting or combination CR with cold stimuli have any effects on mental and physical health-related markers, and to clarify if different…
- Conditions
- Calorie Deficiency, Fasting, Cold Exposure
- Trial name
- NCT05545943
- Testing
- 2-days of zero calorie restriction and whole-body cold-water immersion, 6-days of calorie restriction, 2-days of zero calorie restriction without whole-body cold-water immersion
- Where
- Lithuania
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Obesity
Investigation of Waist Circumference and Waist/Hip Ratio as a Predictive Risk Factor for Morbidity and Mortality After Colorectal Surgery
Despite advances in surgical technique, preoperative patient evaluation and post-operative care, elective colorectal surgery carries a risk of mortality of approximately 2% and a morbidity rate ranging from 20-40%.
- Trial name
- NCT01737515
- Testing
- Abdominal waist and hip circumference
- Volunteers
- 1,415 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Bronchiectasis Adult, Osteoporosis, Osteopenia
Role of NLRP3 Inflammasone and Hypoxia in the Severity of Osteoporosis in Patients With Bronchiectasis
The objectives of this research grant are to determine the association of hypoxia with the severity of osteoporosis in the patients with bronchiectasis and whether the mechanism of inflammation is triggered by inflammasones…
- Trial name
- NCT03467035
- Testing
- Inflammasone
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chun-Hua Wang, MD
HFpEF - Heart Failure With Preserved Ejection Fraction, HFmrEF
US Benchmarking Clinical Study
The goal of this observational study is to measure shear wave velocity (SWV) in patients with non-reduced left ventricular ejection fraction (LVEF) heart failure and left ventricular hypertrophy, with or without transthyretin…
- Conditions
- HFpEF - Heart Failure With Preserved Ejection Fraction, HFmrEF, ATTR-CM (Transthyretin Amyloid Cardiomyopathy), Left Ventricular Hypertrophy
- Trial name
- EMS-CT-1 (NCT07215715)
- Where
- 3 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- eMyosound SAS
Malnutrition, Surgery
Post-discharge Nutrition and Resistance Training in Surgical Patients
Randomized intervention by nutritional supplements and training in postoperative patients after discharge
- Trial name
- MaSu (NCT03327935)
- Testing
- Nutrition
- Where
- Faroe Islands
- Volunteers
- 45 people
- Sponsor
- University of Copenhagen
Cardiovascular Diseases, Atherosclerosis
Insulin Resistance Atherosclerosis Study (IRAS)
To conduct a multicenter study of the relationship between insulin resistance and cardiovascular disease (CVD) and its risk factors in a tri-ethnic (African-American, Hispanic, and non-Hispanic white) population aged 40 to 69…
- Conditions
- Cardiovascular Diseases, Atherosclerosis, Diabetes Mellitus, Heart Diseases
- Trial name
- NCT00005135
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Obesity, Bariatric Surgery Candidate
Efficacy of a Mobile Application and Semi-attendance Program in Bariatric Surgery
BACKGROUND: Applications for mobile devices in patients with obesity offer a great opportunity to improve the quality of care and the monitoring of patients in bariatric surgery programs.
- Trial name
- NCT06163235
- Testing
- Obemar platform
- Volunteers
- 72 people
- Sponsor
- Parc de Salut Mar