Clinical trials: Metabolic Health
Cardiometabolic Syndrome, Type 2 Diabetes
Circadian Intervention to Improve Cardiometabolic Health
The overall goal is to examine the efficacy of a circadian intervention in people with overweight and obesity and habitual short sleep duration (HSSD).
- Conditions
- Cardiometabolic Syndrome, Type 2 Diabetes, Sleep, Time Restricted Feeding
- Trial name
- TOCS (NCT05943626)
- Testing
- Circadian Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Utah
Anemia, Intrauterine Growth Retardation
Impact of Pre-pregnancy Micronutrient Supplementation on Maternal and Child Outcomes
The study evaluates the efficacy of providing weekly iron-folate (IFA) supplements or Multiple Micronutrient (MM) supplements before pregnancy in increasing birth weight and duration of gestation as well as maternal and infant…
- Conditions
- Anemia, Intrauterine Growth Retardation, Preterm Delivery, Iron Deficiency
- Trial name
- NCT01665378
- Testing
- Multiple Micronutrient, Iron and Folic Acid, Folic Acid
- Where
- Vietnam
- Volunteers
- 5,011 people, healthy volunteers welcome
- Sponsor
- Emory University
Metabolic Disease, Insulin Resistance
Walking Before or After Breakfast - Which is Better to Improve Health in Overweight Individuals?
The aim of this study is to investigate the effectiveness of a home-based walking-based exercise intervention undertaken in the fed or fasted state to improve glycaemic control in overweight and obese individuals.
- Trial name
- NCT06240663
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 34 people
- Sponsor
- Liverpool John Moores University
Health Maintenance, Diabetes
UCLA Health Patient Health Maintenance Text Reminder July 2023
This is a prospective randomized clinical trial evaluating how behaviorally-informed outreach text message reminders impact patient engagement with primary care.
- Conditions
- Health Maintenance, Diabetes, Cancer
- Trial name
- NCT05979987
- Testing
- Reminder of preventive care measures, Persuasion via anecdote, Persuasion via anecdote without link
- Where
- United States
- Volunteers
- 6,894 people
- Sponsor
- University of California, Los Angeles
Yoga, Obesity
Feasibility and Impact of Yoga in Obesity
Yoga may confer health benefits in people with overweight or obesity that enhance weight loss and weight loss maintenance. This study aims to investigate the feasibility of integrating yoga into an established behavioral weight…
- Conditions
- Yoga, Obesity, Weight Loss
- Trial name
- SYNERGY (NCT05031221)
- Testing
- Yoga + behavioral weight loss
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Colorado, Denver
Osteoporosis, Arthroplasty Complications
Surgeon-Initiated Bone Health Referral Pathway in Patients Undergoing Lower Extremity Arthroplasty
The goal of this clinical trial is to observe the impact of a surgeon-driven bone health referral pathway following lower extremity arthroplasty.
- Conditions
- Osteoporosis, Arthroplasty Complications, Fragility Fracture
- Trial name
- NCT05845021
- Testing
- Surgeon-Initiated Bone Health Referral Pathway
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Osteoporosis, Bone Loss
Dairy Foods Compared to Dietary Supplements and Bone Health
Does the consumption of dairy foods reduce the rate of bone loss in older women more than calcium and vitamin D supplements.
- Conditions
- Osteoporosis, Bone Loss, Osteopenia
- Trial name
- FL-83 (NCT01394484)
- Testing
- Intervention I, Intervention II
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Type 2 Diabetes
Health Benefits of Aerobic and Resistance Training in Individuals With Type 2 Diabetes
The goal of the proposed study, Health Benefits of Aerobic and Resistance Training in individuals with type 2 diabetes (HART-D), is to compare the effect of resistance training alone (RT), resistance in combination with aerobic…
- Trial name
- HART-D (NCT00458133)
- Testing
- exercise
- Where
- United States
- Volunteers
- 262 people
- Sponsor
- Pennington Biomedical Research Center
Overweight and Obesity, Signs and Symptoms
Implications of Self-weighing During Weight Loss Treatment
This study aims to analyze the effectiveness of introducing behavioral elements in a weight loss program, in this case, comparing the difference between self-weighing versus not doing so.
- Conditions
- Overweight and Obesity, Signs and Symptoms, Behavior, Eating
- Trial name
- NCT04032249
- Testing
- Control Group (CG), Intervention Group (IG)
- Where
- Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidad de Córdoba
Diabetes Mellitus
Optimising Health in Type 1 Diabetes
Type 1 diabetes is an autoimmune condition where circulating immune cells destroy the beta-cells in the pancreas that make insulin, resulting in a degree of insulin deficiency, whereby blood glucose levels rise and diabetes…
- Trial name
- NCT02903615
- Testing
- Novel diet, Standard diet
- Where
- 2 sites in Australia
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Garvan Institute of Medical Research
Dehydration, Dehydration (Physiology)
Adequate Hydration and Health Outcomes
Cardiovascular diseases (CVD) are the leading cause of death in middle- and high-income countries, according to data from the World Health Organization (WHO).
- Conditions
- Dehydration, Dehydration (Physiology), Glucose Abnormalities, Cardiovascular
- Trial name
- HYDRATE (NCT07179107)
- Testing
- Baseline - week 1, Low Water Intake - week 2, Moderate Water Intake - week 3
- Where
- 2 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Metabolic Syndrome, Obesity
Low-intensity Exercise in Metabolic Syndrome
People with metabolic syndrome (MetS) are characterized by a lower quality of life in terms of reduced vital activity, emotional state, and social functioning.
- Conditions
- Metabolic Syndrome, Obesity, Hypertension, Hyperlipidemias
- Trial name
- NCT04346836
- Testing
- Low-intensity, general-fitness exercises, Psychoeducation
- Where
- Poland
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Wroclaw University of Health and Sport Sciences
Obesity
Sweeteners and Sweetness Enhancers: Prolonged Effects on Health, Obesity and Safety
The aim of this randomised controlled trial (RCT) is to investigate if prolonged consumption of sweetener and sweetness enhancers (S\&SEs) within a healthy diet approach will improve weight loss maintenance and obesity related…
- Trial name
- SWEET (NCT04226911)
- Testing
- S&SEs, Sugar
- Where
- 4 sites in Denmark, Greece and 2 more
- Volunteers
- 379 people, healthy volunteers welcome
- Sponsor
- Anne Birgitte Raben
Pregnant Women With Singleton Pregnancies
Harvesting Health: Advancing Nutrition and Wellness for Moms and Babies
This is a randomized controlled trial to assess whether a personalized food kit to pregnant women is feasible, improves diet quality, and enhances pregnancy and birth outcomes compared to standard prenatal care.
- Trial name
- HH (NCT07659821)
- Testing
- Food Kit
- Where
- 3 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Obesity (Disorder)
Repeated Far Infrared Sauna Bathing in Adults With Obesity
This is a clinical trial to determine if 30 sessions of far infrared sauna bathing can improve cardiovascular and metabolic function in adults with obesity.
- Trial name
- NCT07158047
- Testing
- Heat therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Oregon
Diabetes Mellitus, Type 2
Call-2-Health: Preventing Type II Diabetes
It is estimated that 30 million U.S. adults will have type 2 diabetes by 2050. Contributing to this national trend is the obesity epidemic.
- Trial name
- C2H (NCT01827826)
- Testing
- Telephonic intervention to prevent Diabetes Mellitus, Type 2
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Hyperlipidemia, Diabetes
Tele-Pharmacy Intervention to Improve Treatment Adherence
The purpose of this cluster randomized controlled trial is to evaluate whether a novel tele-pharmacist-based intervention for patients with hyperlipidemia, hypertension, and diabetes improves medication adherence, disease…
- Conditions
- Hyperlipidemia, Diabetes, Hypertension
- Trial name
- STIC2IT (NCT02512276)
- Testing
- Telepharmacist intervention
- Where
- United States
- Volunteers
- 4,078 people
- Sponsor
- Brigham and Women's Hospital
Type 1 Diabetes, Adolescent Development
Emoticare: Serious Game for the Adaptation to the Disease of Adolescents With Type 1 Diabetes Mellitus.
The intervention program targets adolescents with chronic Type 1 Diabetes Mellitus. Given the critical developmental stage and life transitions, necessitating robust personal resources, psychological support becomes imperative.
- Trial name
- NCT06331429
- Testing
- EmoTiCare
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- University of Valencia
Severe Acute Malnutrition, Health Care Associated Infection
Prevention of Nosocomial Infections (CleanKids)
While the standardization of treatment protocols for Severe Acute Malnutrition (SAM) has helped to reduce historically high mortality, mortality in inpatient settings remains substantial, likely due to the severity of…
- Conditions
- Severe Acute Malnutrition, Health Care Associated Infection, Multi Drug Resistant Organisms
- Trial name
- CleanKids (NCT03360877)
- Testing
- Health-care associated infection (HCAI)
- Volunteers
- 4,944 people
- Sponsor
- Epicentre
Diabetes Mellitus, Type 2, Gestational Diabetes
Community Health Worker-Led Postpartum Diabetes Screening
Women who experience gestational diabetes are at high risk of developing type 2 diabetes mellitus in the postpartum period-especially in low- and middle-income countries like India where the burden of diabetes is high and…
- Trial name
- NCT06209411
- Testing
- Home Based Testing, Clinic Based Screening, Food order nutritional intervention before meals
- Where
- India
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University