Clinical trials: Metabolic Parameters
Obesity & Overweight, Morbid Obesity
Investigation of the Effects of Whole Body Vibration Application on Muscle Functional Level, Physical Fitness and Respiratory Parameters After Bariatric Surgery
The aim of this study was to investigate the effects of whole body vibration on muscle functional level, physical fitness and respiratory parameters after bariatric surgery.
- Conditions
- Obesity & Overweight, Morbid Obesity, Morbid Obesity Requiring Bariatric Surgery
- Trial name
- NCT07602959
- Testing
- Resistance Training, Whole Body Vibration, Control Group
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Arrhythmias, Cardiac, Diabetes Mellitus
Effect of Dapagliflozin on Electrocardiographic Parameters in Type 2 Diabetes Patients: DAPA - ECG Study
The goal of this clinical trial is to evaluate whether dapagliflozin can reduce ventricular electrical remodeling, as measured by electrocardiographic parameters, in patients with type 2 diabetes (T2D).
- Trial name
- DAPA-ECG (NCT06721442)
- Testing
- Dapagliflozin (DAPA)
- Where
- 2 sites in Brazil
- Volunteers
- 174 people
- Sponsor
- Beneficência Portuguesa de São Paulo
Stroke, Osteoporosis
Osteoporosis After Stroke
The aim of this study was to investigate the clinical features affecting bone mineral density in plegic and non-plegic extremities in hemiplegic patients with stroke in the subacute and chronic phases.
- Trial name
- NCT07059468
- Testing
- Bone mineral density/ Bone mineral density (BMD) will be measured on the lumbar spine (L1-L4) and femoral neck by dual X-ray absorptiometry (DXA)
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Metabolic Syndrome
Effects of Cornelian Cherry Supplementation in Patients With Metabolic Syndrome
This randomized, double-blind, placebo-controlled, parallel-group study evaluated the effects of six-month oral supplementation with Cornus mas fruit lyophilizate in patients with metabolic syndrome.
- Trial name
- NCT07739602
- Testing
- Cornus mas Fruit Lyophilizate
- Where
- Poland
- Volunteers
- 55 people
- Sponsor
- Wroclaw Medical University
Obesity & Overweight
Effect of 8 Weeks of Resistance Training With Blood Flow Restriction on Muscle Strength, Clinical Parameters, Biochemical Biomarkers, and Perceived Exertion in Adults With Obesity
To analyze the effect of 8 weeks of resistance training with blood flow restriction on muscle strength, clinical parameters, biochemical biomarkers, and perceived exertion in adults with obesity.
- Trial name
- NCT07444736
- Testing
- Intervention
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Centro Universitario de Tlajomulco, Universidad de Guadalajara
Type 2 Diabetes
The Effect of the Interdisciplinary Care Approach on General Health Parameters in Older Adults With Type 2 Diabetes
The aim of the study was evaluation of the effect of the clinical Pilates, nurse coaching and Peer group work Approach on General Health Parameters in older adults with Diabetes.
- Trial name
- NCT07165119
- Testing
- Interdisciplinary group, Clinical Pilates Group, Nurse Coaching group
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Hacettepe University
Obesity, Weight Loss
Changes in Anthropometric, Biochemical and DNA Damage Parameters After 3-weeks VLCD in Severely Obese Patients
Obesity manifest with inflammation, hyperglycaemia and dyslipidaemia. These conditions disturb redox system by generating excessive reactive oxygen species (ROS) and causing oxidative stress (OS) leading to DNA damage.
- Conditions
- Obesity, Weight Loss, DNA Damage
- Trial name
- NCT05007171
- Testing
- Very low calorie diet
- Where
- Croatia
- Volunteers
- 22 people
- Sponsor
- Special Hospital for Extended Treatment of Duga Resa
Type 2 Diabetes Mellitus
Study to Evaluate the Potential Pharmacokinetic Interaction and Pharmacodynamic Effects on Renal Parameters of Bumetanide (1mg) and Dapagliflozin (10 mg) When Co-administered in Healthy Subjects
To assess the potential pharmacokinetic (PK) interactions of bumetanide and dapagliflozin following multiple doses of 1 mg bumetanide and 10 mg dapagliflozin in healthy subjects
- Trial name
- NCT00930865
- Testing
- Bumetanide, Dapagliflozin
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Overweight, Obesity
Vitamin D Effects in Overweight Patients
The purpose of the study is to investigate in overweight patients who are on a telemedically guided weight loss program the influence of a daily vitamin D supplement on weight loss and body composition, selected inflammation…
- Trial name
- SMART (NCT00493012)
- Testing
- vitamin D
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Heart and Diabetes Center North-Rhine Westfalia
Type 2 Diabetes
Effects of BKR-017 on Insulin Resistance in Type 2 Diabetes Patients
The purpose of this study is to evaluate the effect of BKR-017 on insulin resistance in type 2 diabetes (T2D) subjects during 28 days of active test product administration.
- Trial name
- NCT04279444
- Testing
- BKR-017
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- BioKier Inc.
Type2 Diabetes Mellitus
n-3 Fatty Acid Effects in T2DM After Acute High Intensity Exercise
The aim of this study was to verify the effect of a combined supplementation [n-3 PUFA (known to induce anti-inflammatory effects) plus vitamin E (known for its antioxidant properties)] on lipidic, glycemic, redox status and…
- Trial name
- NCT03182712
- Testing
- n-3 PUFA Group
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of Rio Grande do Sul
Cardiometabolic Syndrome
Effects of Berberine on Cardiometabolic Outcomes
Cardiovascular disease, type 2 diabetes mellitus and associated diseases combined are the leading health burden and cause of mortality worldwide; therefore, the necessity for an intervention is paramount.
- Trial name
- NCT07541898
- Testing
- Berberine
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Central Lancashire
Type 2 Diabetes
Evaluation of the Effect of Pomegranate Peel Added Bread on Blood Sugar, Fats, and the Body's Defense Response
The aim of this study is to evaluate the effects of the consumption of bread produced with the addition of pomegranate peels, which has a high antioxidant content, on blood glucose and lipid parameters, and some…
- Trial name
- NCT05232305
- Testing
- Pomegranate Peel
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Toros University
Diabetes Mellitus, Type 2
A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Germany, as Part of Local Clinical Practice
The purpose of the study is to collect information on how Rybelsus® works in people with type 2 diabetes and to see if Rybelsus® can lower their blood sugar levels.
- Trial name
- PIONEER REAL (NCT05473286)
- Testing
- Oral Semaglutide
- Sponsor
- Novo Nordisk A/S
PET-CT, Lymphoma
PET-CT in Lymphoma Among the Eldery
This study investigates PET-CT imaging patterns and metabolic parameters in elderly patients (≥60 years) diagnosed with lymphoma, aiming to enhance diagnostic accuracy and prognosis using 18F-FDG PET/CT scans.
- Conditions
- PET-CT, Lymphoma, Elderly, Metabolic Parameters
- Trial name
- NCT07259941
- Volunteers
- 63 people
- Sponsor
- Assiut University
Endometriosis, Bone Density
BMD Alterations and Bone and Muscle Parameters During Menstrual Cessation With GnRH
The investigators aim to investigate the effect of menstrual cessation in women with endometriosis treated with GnRH analogs for 6 months on bone mineral density and bone and muscle metabolism parameters and subsequently the…
- Conditions
- Endometriosis, Bone Density, Muscle, Bone Metabolism
- Trial name
- NCT04203212
- Testing
- Goserelin Acetate
- Where
- Greece
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- 424 General Military Hospital
Obesity
Laparascopic Sleeve Gastrectomy vs. Endoscopic Gastric Plication in Obesity
The project will describe the efficacy and safety of laparoscopic sleeve gastrectomy and endoscopic gastric plication procedures as compared to conservative therapy and clarify the mechanisms of action of these treatments.
- Trial name
- SLAVIA (NCT05259644)
- Testing
- laparoscopic sleeve gastrectomy, conservative treatment of obesity, endoscopic gastric plication
- Where
- Czechia
- Volunteers
- 75 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Weight Gain
Improving Metabolic Parameters of Antipsychotic Child Treatment With Ziprasidone, Aripiprazole, and Clozapine
The purpose of this study is to evaluate the relative risks and benefits of two approaches to the control of weight gain and other negative side effects in children and adolescents on 2nd generation antipsychotics (SGA): Healthy…
- Trial name
- ZAC (NCT00617058)
- Testing
- metformin, healthy lifestyle intervention
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of North Carolina, Chapel Hill
Covid19, Diabetes Mellitus, Type 2
Blood Sample Measurements and Physical Activity Levels in Type II Diabetes and/or COVID-19
It is known that COVID-19 has a more negative clinical course and causes higher degrees of morbidity and mortality in case of COVID-19 in diabetic patients.
- Trial name
- NCT04695158
- Testing
- COVID-19 group (Group I), Type II Diabetes Mellitus and COVID-19 group (Group II)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir Bakircay University
Diabetes Mellitus, Type 2
A Study To Evaluate The Effects Of PF-05175157 In Healthy Volunteers
The primary purpose of this study is to evaluate pharmacodynamics of single oral doses of PF-05175157 in a dose-dependent fashion in healthy volunteers
- Trial name
- NCT01537497
- Testing
- PF-05175157
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Pfizer