Clinical trials: Metabolic Profiling Muscle, open to volunteers
Metabolic Syndrome, Dialysis; Complications
Plasma Biomarkers of Muscle Metabolism During Exercise to the Assessment of Insulin Resistance in CKD Dialysis Patients
This prospective, multicenter, cross-sectional, repeated-measures comparative study compared functional and biochemical response profiles to exercise between 2 groups of chronically ill patients (chronic renal failure dialysis…
- Trial name
- KREBSome-IRC (NCT06360302)
- Testing
- Exercise test, Blood sample, Impedancemetry
- Where
- 2 sites in France
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
ADHD - Attention Deficit Disorder With Hyperactivity, Fibromyalgia (FM)
Comorbidity Between Attention Deficit Hyperactivity Disorder and Fibromyalgia
The overall objective of the research project presented here is to assess the prevalence of fibromyalgia in patients being treated for ADHD, the prevalence of ADHD in patients being treated for fibromyalgia, and the…
- Conditions
- ADHD - Attention Deficit Disorder With Hyperactivity, Fibromyalgia (FM), Chronic Pain
- Trial name
- HYPERPAIN (NCT07443800)
- Testing
- Samples, Questionnaires, Sensitivity to mechanical pain
- Volunteers
- 100 people
- Sponsor
- University Hospital, Tours
Fibromyalgia, Primary, Pain
Bio-significance of LPC16:0 in Fibromyalgia
Fibromyalgia (FM) is a very common but mysterious pain disorder characterized by chronic widespread muscular pain. Fatigue, anxiety and depression are common comorbidities.
- Conditions
- Fibromyalgia, Primary, Pain, Soreness, Muscle, Oxidative Stress
- Trial name
- NCT04832100
- Testing
- Pregabalin 150mg, imipramine 25mg
- Where
- Taiwan
- Volunteers
- 245 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Obesity, Sarcopenia
Pilot Study of the Human Metagenome in Metabolic Diseases
This is a cohort study to understand the role of the human metagenome, and associated metabolites, in health and in various diseased states, in particular obesity as well as sarcopenia.
- Conditions
- Obesity, Sarcopenia, Sarcopenic Obesity, Chronic Inflammation
- Trial name
- NCT06363253
- Testing
- No specific intervention
- Where
- Singapore
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sengkang General Hospital
Acute Stroke Intervention, Acute Stroke
Using AI Systems to Optimize the Clinical Outcome of Stroke Patients
This project addresses the imminent challenge of providing adequate motor rehabilitation to a growing number of stroke survivors amidst the ageing population, decreasing age of stroke, and shortage of physical/occupational…
- Conditions
- Acute Stroke Intervention, Acute Stroke, Acute Ischemic Stroke
- Trial name
- NCT06828679
- Testing
- Acupuncture, control group, Robotic Training
- Where
- Hong Kong
- Volunteers
- 400 people
- Sponsor
- Chinese University of Hong Kong
Neuromuscular Diseases (NMD), Charcot Marie Tooth Disease (CMT)
Personalized Training for People With Rare Neuromuscular Disorders
The goal of this study is to investigate the effects of personalized exercise treatment on dynamic balance and physical function in comparison with regular follow-up in adults with rare-neuromuscular disorders…
- Conditions
- Neuromuscular Diseases (NMD), Charcot Marie Tooth Disease (CMT), Facioscapulohumeral Muscular Dystrophy, Myotonic Dystrophy Type 1 (DM1)
- Trial name
- PETRA-NMD (NCT06708468)
- Testing
- Exercise, Usual Care
- Where
- 5 sites in Norway
- Volunteers
- 120 people
- Sponsor
- Oslo University Hospital
Cancer Related Fatigue, Fatigue Syndrome, Chronic
Research for Pathophysiology of Cancer Related Fatigue (CRF) and Chronic Fatigue (CFS/ME)
Research for Pathophysiology of Cancer Related Fatigue (CRF) and Chronic Fatigue Syndrome (CFS/ME) by Lipidomics, Metabolomics, Intestinal and Peritoneal Microbiome Analysis and Exome Analysis and Investigation of a Possible…
- Trial name
- IMPROFA (NCT03773003)
- Testing
- Probiotics
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universität des Saarlandes
Ischemic Heart Disease
Hyperpolarized MRSI in Ischemic Heart Disease: A Metabolic Investigation of the Heart Muscle
This study aims to investigate the potential of using hyperpolarized [1-13C]-pyruvate magnetic resonance imaging (MRI) to assess metabolic alterations in patients with ischemic heart disease (IHD).
- Trial name
- NCT06054516
- Testing
- 13C-enriched pyruvate
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Henrik Wiggers
Sarcopenia, Older Adults
Distinct Exercise Modalities on Gut Microbiome
Sarcopenia is a multifactorial muscular disease with detrimental clinical consequences, impairing physical function, functional independence, quality of life, need for long-term care and premature mortality.
- Trial name
- DEMGUTS (NCT06545123)
- Testing
- Concurrent exercise training
- Where
- Portugal
- Volunteers
- 69 people
- Sponsor
- Faculty of Sports- Research Center in Physical Activity, Health and Leisure
Diabetes Mellitus Type 2, Heart Failure
Heart Failure in Patients With Diabetes: Cells, Crosstalk and Consequences
This will be an observational study to explore differences in pathophysiology between groups of people with and without heart failure (HF) (reduced and preserved ejection fraction) and with and without diabetes mellitus (DM) with…
- Conditions
- Diabetes Mellitus Type 2, Heart Failure, HFrEF - Heart Failure With Reduced Ejection Fraction, HFpEF - Heart Failure With Preserved Ejection Fraction
- Trial name
- NCT06774014
- Where
- United Kingdom
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Patients with Clinical Complaints of Fibromyalgia Among the Patients Applying to the Outpatient Clinic, Fibromyalgia Syndrome
Metabolomic Profiling Based on Nuclear Magnetic Resonance in Fibromyalgia Patients
Evaluation of sera of fibromyalgia patients in terms of energy metabolism function and possible alterations in metabolism predisposing to various degenerative/proliferative diseases.
- Trial name
- NCT06725199
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- hatice kübra aşık
Systemic Lupus Erthematosus, Sjogren's Syndrome
Mass Spectrometry-based Immune Profiling in Autoimmune Diseases
Based on mass spectrometry flow method, this study analyzed the typing of new T, B, NK and DC cell subsets in peripheral blood of common autoimmune diseases and their correlation with disease activity, aiming at establishing an…
- Conditions
- Systemic Lupus Erthematosus, Sjogren's Syndrome, Inflammatory Myopathies, Systemic Sclerosis (SSc)
- Trial name
- NCT07188285
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Metabolomics, Critical Care
Metabolomics Study on Postoperative Intensive Care Acquired Muscle Weakness
In this mono-center pilot trial, surgical patients who are at high risk to be admitted to intensive care will be screened and asked for participation.
- Conditions
- Metabolomics, Critical Care, Critical Illness, Critical Illness Myopathy
- Trial name
- MIRACLE I (NCT03810768)
- Where
- 3 sites in Austria, Germany
- Volunteers
- 20 people
- Sponsor
- Technical University of Munich