Clinical trials: Metabolic Regulation
Diabetes Mellitus, Type 2, Glucose Intolerance
Rowing Away From Diabetes
Primary research question: What is the effect of indoor rowing, under the ideal circumstances of a laboratory setting, on glucose control in adults with impaired glucose control? Secondary research question: Is it possible to…
- Conditions
- Diabetes Mellitus, Type 2, Glucose Intolerance, Hyperglycemia
- Trial name
- NCT02444156
- Testing
- Indoor rowing
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Leicester
Diabetes Mellitus, Type 2, Overweight and Obesity
Adaptation of a Digital Weight Loss Intervention Promoting Self-regulation for Use in Type 2 Diabetes
The purpose of this study is to 1) adapt a weight loss app that the Tate team has previously developed to promote PA and diet and adapt them to the needs and perspectives of those with Type 2 Diabetes (T2DM), integrate daily…
- Trial name
- NCT03650088
- Testing
- Behavioral weight loss with digital tools
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of North Carolina, Chapel Hill
Depression, Obesity
Research Aimed at Improving Both Mood and Weight
The RAINBOW study is an NIH R01-funded randomized controlled trial to evaluate the clinical and cost effectiveness and implementation potential of a primary care integrated multicondition intervention program to help improve mood…
- Trial name
- RAINBOW-ENGAGE (NCT02246413)
- Testing
- RAINBOW Intervention Program
- Where
- 2 sites in United States
- Volunteers
- 409 people
- Sponsor
- Palo Alto Medical Foundation
Obesity, Diabetes Mellitus, Type II
Impact of Sleep and Meal Timing on Food Intake Regulation
This study will test the hypothesis that a late sleep (Ls) and/or late meal (Lm) behavioral pattern, with equal sleep duration, will promote positive energy balance and insulin resistance (IR).
- Conditions
- Obesity, Diabetes Mellitus, Type II, Cardiovascular Disease
- Trial name
- NCT02347020
- Testing
- Normal Sleep/ Normal Meal, Normal Sleep/ Late Meal, Late Sleep/ Normal Meal
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Columbia University
Hypoglycaemia
Point of Care Ketone Measurement in the Newborn
Low blood sugar levels are common in babies after birth. This may be normal as babies can use other sources of energy. However if a baby does not produce these fuels the brain can be starved of energy and be damaged.
- Trial name
- POCKET (NCT02341313)
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Kathryn Beardsall
Obesity & Overweight, Emotional Eating Behaviour
Mindfulness-Based Nutrition Group Therapy as an Adjunct to GLP-1 Treatment of Obesity
The goal of this clinical trial is to learn whether a mindfulness-based nutrition group program is feasible and acceptable for adults with obesity who are taking GLP-1 receptor agonist medication and receiving usual medical care…
- Conditions
- Obesity & Overweight, Emotional Eating Behaviour, Mindful Eating Intervention
- Trial name
- MBNGT (NCT07649759)
- Testing
- Mindfulness-based nutritional group therapy (MBNGT)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Bern University of Applied Sciences
Overweight
Identifying the Effect and Working Mechanisms of MyPlan 2.0 in Older Adults
The aim of this study is to investigate whether and how 'MyPlan 2.0' helps older adults to be more physically active or less sedentary. Two groups will be created, an intervention group and a waiting-list control group.
- Trial name
- NCT03799146
- Testing
- MyPlan 2.0, Waiting List
- Where
- Belgium
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University Ghent
Diabetes Mellitus, Type 1
Blood Glucose Awareness Training for Parents
The purpose of this study is to test a training program for parents of children with T1DM.
- Trial name
- NCT00315991
- Testing
- Blood Glucose Awareness Training for Parents
- Where
- 2 sites in United States
- Volunteers
- 77 people
- Sponsor
- University of Virginia
Insulin Resistance, Obesity
De Novo Lipogenesis and Insulin Sensitivity in Obese
Disturbances of de novo lipogenesis (DNL) are one of the features of dysfunction of adipose tissue (AT). Disturbances of DNL play a role in development of metabolic complications of obesity.
- Trial name
- DELISA (NCT04260542)
- Testing
- Fasting/refeeding, Ketogenic diet/ fasting
- Where
- 2 sites in Czechia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Glycogen Storage Disease Type I, Glycogen Storage Disease Type IB
Effects of the Carbohydrate Counting Method on Blood Glucose Regulation, Quality of Life, Urinary Glc4 and Other Biomarkers in Children With GSD1
The goal of the study is to investigate the effects of carbohydrate counting training-administered to pediatric patients diagnosed with GSD 1a and 1b-on blood glucose regulation, quality of life, urinary glucotetrasaccharide…
- Conditions
- Glycogen Storage Disease Type I, Glycogen Storage Disease Type IB, Glycogen Storage Disease Type IA
- Trial name
- NCT07875023
- Where
- Turkey (Türkiye)
- Volunteers
- 8 people
- Sponsor
- Şükrü Arman AKSOY
Impaired Glucose Regulation, Overweight and Obesity
Fermented Dietary Fiber and Probiotics on Overweight/Obese Patients
This study aims to investigate the efficacy of fermented dietary fiber and probiotics in improving glycemic control and associated metabolic parameters in overweight/obese IGR patients.
- Trial name
- NCT06475573
- Testing
- dietary fiber probiotic beverages, whole grain porridge
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Overweight
Caloric Restriction and Body Weight in Adults
The purpose of this study is to determine the role of 1. dietary calcium in fecal fat loss and the association between lactose maldigestion, dietary calcium level and source, and weight loss induced by caloric restriction. 2.
- Trial name
- NCT00808275
- Testing
- Dietary calcium
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Type 2 Diabetes Mellitus
The HOME Trial: Hyperinsulinaemia: the Outcome of Its Metabolic Effects, a Randomized Controlled Trial
The HOME-trial is a prospective, randomized controlled trial. The purpose of this study is to investigate the effects of metformin HCL in patients with type 2 diabetes mellitus intensively treated with insulin on the quality of…
- Trial name
- NCT00375388
- Testing
- Metformin on top of intensive insulin therapy
- Where
- Netherlands
- Volunteers
- 400 people
- Sponsor
- Bethesda General Hospital, Hoogeveen
Type 1 Diabetes
The Effect of Saxagliptin on Glucose Fluctuation and Immune Regulation in Patients With Type 1 Diabetes
To investigate whether saxagliptin could reduce the fluctuation of glycemia and improve the glycemic control in those type 1 diabetes through mechanisms of suppressing glucagon secretion, improving beta cell function, and…
- Trial name
- NCT02307695
- Testing
- Saxagliptin, Insulin
- Where
- China
- Volunteers
- 184 people
- Sponsor
- Nanjing Medical University
Type 2 Diabetes Mellitus
Incretin Therapy and Exercise in Type 2 Diabetes
This study will examine changes in brain and physical health in adults with type 2 diabetes who are initiating incretin-mimetic therapy (e.g., Ozempic, Mounjaro), and determine whether adding structured exercise provides…
- Trial name
- BIOM (NCT07833813)
- Testing
- Structured Exercise Program
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- University of Regina
Obesity, Type II Diabetes Mellitus
Yellow Pea Protein and Fibre and Short Term Food Intake
It is hypothesized that yellow pea protein and fiber will reduce short-term food intake, subjective appetite and glycemic response.
- Conditions
- Obesity, Type II Diabetes Mellitus, Metabolic Syndrome
- Trial name
- NCT01255085
- Testing
- yellow pea protein, yellow pea fiber, Control Tomato Soup
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity
Determinants of Post-Exercise Eating Patterns
This study examines potential physiological and psychological determinants of food intake in response to exercise. Specifically, beyond measuring actual food consumption and physiological markers typically assessed during…
- Trial name
- DEEP (NCT03643315)
- Testing
- Exercise and Meal (EX), No-Exercise and Meal (NEX)
- Where
- Singapore
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Obesity, Women
Lactobacillus Gasseri and Hormonal Regulation in Obese Women
To evaluate the regulatory effect of Lactobacillus gasseri LG08 formula on visceral fat metabolism and sex hormone balance in obese women.
- Trial name
- NCT07502404
- Testing
- Probiotic, Maltodextrin
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Obesity
CHRONOtype-adjusted DIET on Weight Loss
BACKGROUND: Several reports have observed that the alteration of normal biological rhythms is associated with obesity development.
- Trial name
- CHRONO-DIET (NCT03755674)
- Testing
- CHRONOTYPE-ADJUSTED DIET
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Diabetic Cardiomyopathies, Type2 Diabetes
Effect of High-intensity Interval Training on Cardiac Function and Regulation of Glycemic Control in Diabetic Cardiomyopathy
According to data of the International Diabetes Federation (IDF), diabetes in general affects approximately 415 million people worldwide and this number is still increasing.
- Trial name
- NCT03299790
- Testing
- high-intensity interval exercise training (HIIT), moderate-intensity exercise training (MIT)
- Where
- Belgium
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Hasselt University