Clinical trials: Metabolic Regulation
Obesity, Weight Loss
Impacts of Wild Blueberries on Appetite and Weight Regulation
The objective is to complete a two-phase study to assess how wild blueberries impact regulation of appetite of overweight and obese men and women as well as to determine if wild blueberries can promote more effective weight loss…
- Trial name
- NCT05736432
- Testing
- Blueberries
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Obesity, Weight Gain
Exercise, Brain Activity, and Weight Maintenance
This study aims to explore how HIIT influences brain function, neural and molecular pathways related to weight control, setting the stage for future obesity intervention research.
- Conditions
- Obesity, Weight Gain, Bariatric Surgery Candidate, Appetitive Behavior
- Trial name
- NCT06511310
- Testing
- Exercise
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Joslin Diabetes Center
Neuroendocrine Reproductive Status
Impacts of Metabolic Variation on Neuroendocrine Control of Reproduction
This study will evaluate the potential effects of a changing metabolic environment on GnRH hypothalamic neurons, by performing studies of LH pulsatility (basal and during clamp studies) in different groups of male subjects fed…
- Trial name
- NCT01058681
- Testing
- effect of metabolic variations on LH pulsatility
- Where
- Switzerland
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Obesity
Promoting The Self-Regulation Of Energy Intake
The goal of this study is to develop and test the efficacy of a scientifically-based, culturally competent seven-session parent directed, obesity prevention program focused on parental feeding strategies that support young…
- Trial name
- SEEDs (NCT01513343)
- Testing
- Parent and child groups focused on self-regulation of eating
- Where
- 2 sites in United States
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Abdominal Obesity, Metabolic Syndrome
Acupuncture in the Regulation of Dai Meridian for the Metabolism of Visceral Adipose Tissue in Abdominal Obese Patients
To evaluate the effectiveness of acupuncture therapy combined with healthy education for patients with abdominal obesity.
- Trial name
- NCT02427347
- Testing
- Acupuncture, Healthy education
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Dongfang Hospital Beijing University of Chinese Medicine
Obesity, Overweight
Effects of Meal Energy Density on Body Measures and Metabolism in Women
This study investigates whether the timing of energy intake during the day-specifically consuming more calories at breakfast or at dinner-affects body measurements, blood sugar levels, cholesterol, and feelings of hunger in women…
- Conditions
- Obesity, Overweight, Appetite Regulation, Meal Timing
- Trial name
- NCT07066618
- Testing
- Breakfast-Loaded Hypocaloric Diet, Dinner-Loaded Hypocaloric Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Melike Nur Eroğlu
Intellectual Disability, Rubinstein-Taybi Syndrome
Functional Tests to Resolve Unsolved Rare Diseases. Rares.
Rares diseases are a heterogeneous group of conditions which need important tools for diagnosis. The use of high-throughput sequencing is able to diagnose half of the patients.
- Conditions
- Intellectual Disability, Rubinstein-Taybi Syndrome, Cystic Fibrosis, Congenital Heart Defect
- Trial name
- RID (NCT05696912)
- Testing
- Ex-vivo approach concerning 25 patients, In-vitro approach concerning 25 patients
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bordeaux
Type 2 Diabetes Mellitus
The Effects of Soy Isoflavones to Improve the Metabolism of Glucose and Lipids
Many studies showed that soy foods or soy isoflavones can lower the risk of cardiovascular disease (CVD), osteoporosis and some cancers, but few human studies assessed effects of purified isoflavone components (genistein and…
- Trial name
- NCT00951912
- Testing
- Daidzein, Genistein
- Where
- China
- Volunteers
- 165 people
- Sponsor
- Sun Yat-sen University
Obesity
Metacognitive Beliefs in Obese Patients
The study aims to investigate the presence of metacognitive beliefs, emotional regulation, and emotional eating in obese patients and their possible relationships.
- Trial name
- METAOBES (NCT06800911)
- Testing
- Questionnaires
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Istituto Auxologico Italiano
Obesity
Enhancing Self Regulation as a Strategy for Obesity Prevention in Head Start Preschoolers
The goal of this integrated project targeting the Childhood Obesity Prevention Challenge Area is to reduce the prevalence of obesity among children attending Head Start in Michigan.
- Trial name
- NCT01398358
- Testing
- Parents of Preschoolers Series, Incredible Years Series
- Where
- United States
- Volunteers
- 697 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Obesity, Healthy
Meal-regulated Substrate Metabolism, Influence of Obesity and IL-6
The overall purpose of this explorative yet quantitative study project is to understand how blocking IL-6 signaling leads to the expansion of adipose tissue mass in humans in vivo.
- Trial name
- NCT04687540
- Testing
- Tocilizumab, Saline 0.9%
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Appetite Regulation
The Effect of Dietary Fibre and Plant Protein on Appetite and Metabolic Function
Acute effects on appetite and metabolic function have been observed for whole-grain rye cereal products. The aim of this study is to evaluate if the appetite suppressing effect of a whole-grain rye breakfast cereal may be further…
- Trial name
- NCT01965210
- Testing
- Rye + high dose inulin + low dose gluten, Rye + equal doses of inulin & gluten, Rye + low dose inulin + high dose gluten
- Where
- Sweden
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Swedish University of Agricultural Sciences
Metabolic Disorders, Abdominal Obesity
Exploring Physical Exercise for the Regulation and Control of Metabolic Disorders in College Students.
This clinical trial objective is to evaluate the effect of an aerobic physical exercise program on reducing triglycerides, blood pressure, abdominal obesity, altered glucose levels, and the increase in HDL in college-level…
- Conditions
- Metabolic Disorders, Abdominal Obesity, Blood Pressure Disorders, Hypertriglyceridemia
- Trial name
- (EPE_RCTMCS) (NCT06555159)
- Testing
- Physical exercise prescription: Continuous aerobic training (jogging, swimming, static cycling), Control group: Continuous aerobic physical exercise
- Where
- Mexico
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universidad de Colima
Pregnant Women, Gestational Diabetes
Physical Acvitiy in Pregnancy
The goal of this observational study is to learn how a physically active lifestyle during pregnancy affects placental development and function.
- Conditions
- Pregnant Women, Gestational Diabetes, Obese But Otherwise Healthy Participants, Overweight (BMI > 25)
- Trial name
- NCT07356180
- Testing
- Pregnancy Physical Activity Questionnaire (PPAQ)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Maryland, Baltimore
Healthy, Healthy Volunteers
Effects of Low Fat Versus Low Carbohydrate Diets on Energy Metabolism
Background: Researchers want to learn how different diets affect hormone levels, body weight, energy expenditure, liver fat, and more. To do this, they will use specialized techniques and food plans.
- Trial name
- NCT03878108
- Testing
- LCHF diet, LFHC diet
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Prader Willi Syndrome, Syndromic Obesity
Prader-Willi Syndrome Macronutrient Study
The overall objective is to explore the mechanisms by which macronutrients regulate food intake and weight gain in Prader Willi Syndrome (PWS).
- Conditions
- Prader Willi Syndrome, Syndromic Obesity, Childhood Obesity
- Trial name
- NCT02011360
- Testing
- Low Carbohydrate diet, Low Fat diet
- Where
- 2 sites in United States, Canada
- Volunteers
- 10 people
- Sponsor
- Duke University
Leptin Deficiency, Obesity
Clinical Evaluation of Polyherbal Coded Formulation Obesecure for Leptin Regulation and Obesity Management
The study was designed to explore an alternative approach to reduce weight in human beings using a polyherbal formulation. A polyherbal formulation named as Obesecure was developed after screening of local medicinal flora.
- Trial name
- CEOLO (NCT04443790)
- Testing
- Leptin Human
- Where
- Pakistan
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Hafiz Muhammad Asif
Weight Loss, Weight Gain Prevention
Improving Appetite Regulation in Patients With Obesity
Over 70% of U.S. adults have overweight or obesity. Currently, the most efficacious behavioral intervention for obesity is standard behavioral treatment (SBT), often composed of group sessions, calorie goals, and physical…
- Conditions
- Weight Loss, Weight Gain Prevention, Obesity
- Trial name
- NCT05200520
- Testing
- Appetite Self-Regulation Intervention
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Obesity, Depression
Engaging Self-regulation Targets to Improve Mood and Weight and Understand Mechanism in Depressed and Obese Adults
Multimorbidity (i.e., the coexistence of 2 or more chronic conditions in an individual) is increasingly recognized as a pressing public health problem.
- Trial name
- NCT03841682
- Testing
- I-CARE2
- Where
- 2 sites in United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Obesity
A Comparison of the Metabolic Effects of Fructose, Glucose, High Fructose Corn Syrup and Sucrose at Normal Population Consumed Levels in Adults Aged 20-60 Years Old
The purpose of this study is to investigate the acute and chronic effects of consumption fructose containing sugars and glucose in a real word setting when consumed in a manner and amount typical in the American diet.
- Trial name
- NCT01797042
- Testing
- Dietary Compliance
- Where
- United States
- Volunteers
- 366 people, healthy volunteers welcome
- Sponsor
- Rippe Lifestyle Institute