Clinical trials: Metabolic Risk Factors
Tumors of the Central Nervous System, Childhood Cancer Survivors
Cardiovascular Disorders and Risk Factors in Childhood Cranial and Craniospinal Tumors Survivors
The purpose of research is to study to adverse cardiovascular disorder and risks factors in childhood cranial and craniospinal tumors survivors.
- Trial name
- NCT05641636
- Testing
- 12-lead ECG, hormone and lipid blood tests, echocardiography (Echo-CG), cardiopulmonary exercise testing (CPET) and pulse wave analysis
- Where
- Russia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Metabolic Syndrome
Metformin in Postmenopausal Women With Metabolic Syndrome
The purpose of this study is to determine the effects of metformin on cardiovascular risk factors in postmenopausal women with metabolic syndrome.
- Trial name
- NCT01342744
- Testing
- Metformin
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Childhood Obesity, Dyslipidemia
Nutritional Treatment of Overweight Adolescents With Cardiovascular Risk Factors (PowerUp)
This study is designed to evaluate the efficacy of two diets, a low glycemic load diet and a low saturated fat diet, in the treatment of adolescents with some heart disease risk factors associated with being overweight, such as…
- Conditions
- Childhood Obesity, Dyslipidemia, Insulin Resistance, Hypertension
- Trial name
- NCT00477477
- Testing
- Diet
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Boston Children's Hospital
MAFLD, Metabolic Abnormalities
Frequency of MAFLD and Its Association With Nutritional Status and Metabolic Risk Factors in a Rural Population of Bangladesh
Metabolic dysfunction-associated fatty liver disease (MAFLD) is an increasingly recognized cause of chronic liver disease and is closely linked with obesity, metabolic abnormalities, and nutritional status.
- Conditions
- MAFLD, Metabolic Abnormalities, Obesity & Overweight
- Trial name
- NCT07470749
- Where
- Bangladesh
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Cardiovascular Diseases, Heart Diseases
Precursors of CVD Risk Factors--Project Heartbeat
To elucidate the changes in body size, composition, and configuration occurring in adolescence, because these are important precursors of change in blood pressure and blood lipids.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypercholesterolemia, Hypertension
- Trial name
- NCT00005478
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Type 2 Diabetes
Educative Intervention to Improve Type 2 Diabetes Mellitus Control in Corrientes
Objective: To evaluate the effect of system interventions (data recording procedures and complete coverage of medications and supplies) with or without physician and/or patient education, upon the psychological, clinical…
- Trial name
- PRODIACOR (NCT01456806)
- Testing
- Education
- Where
- Argentina
- Volunteers
- 468 people
- Sponsor
- Centro de Endocrinologia Experimental y Aplicada
Fall Injury, Hip Fractures
Fall, Fracture and Frailty
This project aims to improve the global outcome for an aging individual after a traumatic fall, through identifying conditions contributing to a fall and promoting recovery and rehabilitation.
- Conditions
- Fall Injury, Hip Fractures, Risk Reduction, Osteoporosis, Osteopenia
- Trial name
- FFF (NCT05712252)
- Where
- Sweden
- Volunteers
- 1,200 people
- Sponsor
- Region Skane
Hypertension, Hypercholesterolemia
Vascular Intervention Strategies Trial for Alzheimer's
The proposed pharmacist-led study is a feasibility pilot trial for the management of vascular risk factors of hypertension and hypercholesterolemia in 10 APOE ε4 carriers, 50-75, at-risk for dementia.
- Conditions
- Hypertension, Hypercholesterolemia, Dementia Risk Factors
- Trial name
- VISTA (NCT07447206)
- Testing
- Angiotensin Receptor Blockers (ARBs), Hydrophilic Statins or Non-Statin Alternative
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Southern California
Gestational Diabetes
The OHSU Pregnancy Exercise & Nutrition (PEN) Program
Personal behaviors can influence development of Gestational Diabetes Mellitus (GDM), a condition that can adversely affect the pregnant woman, her developing fetus and future events for both.
- Trial name
- PEN (NCT01719406)
- Testing
- Intervention, behavioral lifestyle education
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Laparoscopic Sleeve Gastrectomy, Cardiovascular Risk Factor
Impact of Sleeve Gastrectomy on Monocyte-to-High-Density Lipoprotein Cholesterol Ratio
The present study hypothesized that significant weight loss is associated with a reduction in the inflammatory markers, leading to diminished cardiovascular risks in patients undergoing laparoscopic sleeve gastrectomy (LGS).
- Conditions
- Laparoscopic Sleeve Gastrectomy, Cardiovascular Risk Factor, Obesity
- Trial name
- NCT04439851
- Volunteers
- 125 people
- Sponsor
- Umraniye Education and Research Hospital
Lifestyle, Healthy, Muscle Weakness
RE-inventing Strategies for Healthy Ageing; Recommendations and Tools
The goal of the RESTART RCT is to examine whether a complex lifestyle intervention, coordinated with municipal and non-government organizations (NGO), can establish and preserve improvements in risk factors and functional…
- Conditions
- Lifestyle, Healthy, Muscle Weakness, Abdominal Obesity, Cardiometabolic Syndrome
- Trial name
- RESTART (NCT06122441)
- Testing
- Complex lifestyle intervention, Physical activity monitoring and recommendations
- Where
- Norway
- Volunteers
- 119 people
- Sponsor
- University of Tromso
PTSD, Cardiovascular Disease
Lifestyle and Cardiometabolic Risk in Post-9/11 Veterans
Heart disease and diabetes are leading causes of death and disability in the US, especially among Veterans. Posttraumatic stress disorder (PTSD) is a disabling condition that also affects many Veterans.
- Conditions
- PTSD, Cardiovascular Disease, Metabolic Syndrome
- Trial name
- NCT04911153
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cardiovascular Diseases, Coronary Disease
Coronary Heart Disease Risk Factors in Upwardly Mobile Blacks and Whites
To evaluate the relation between blood pressure and socioeconomic status, electrolyte intake, obesity and psychosocial factors in Black and white students.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Hypertension, Heart Diseases
- Trial name
- NCT00005175
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Osteoporosis, Osteopenia
The Impact of Hormonal Contraceptive Use and Lifestyle Factors on Fracture Risk and Bone Quality in Young Female Adults
The study on hand is based on a cross-sectional design and aims to acquire 1) descriptive data on the physical state and health condition of female soldiers in the German armed forces.
- Conditions
- Osteoporosis, Osteopenia, Fracture Reduction, Body Composition
- Trial name
- FH (NCT06608862)
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Bundeswehr University Munich
Obesity, Hypertension
Pathophysiology of Cardiometabolic Risk Factors in African Americans
The overall goal of this proposal is to determine the autonomic and nitric oxide contribution in the pathogenesis of hypertension and insulin resistance in obese African American women.
- Trial name
- NCT01122407
- Testing
- L-NMMA, Trimethaphan
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Lung Cancer, Nonsmall Cell
Folate One-carbon Malnutrition as the Metabostemness Risk Factor of Malignancy Tumor Development of NSCLC Patients
Non-small cell lung cancer (NSCLC) accounts for more than two-thirds of lung cancer, which is the leading cause of cancer deaths in Taiwan. The overall prognosis of NSCLC is poor with low 5-year survival rates.
- Trial name
- NCT03504098
- Testing
- nutrition consult
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Morbid Obesity, Exercise
Semi-supervised Exercise Program Before Bariatric Surgery
Background: Patients awaiting bariatric surgery, apart from suffering higher BMI, show a large number of comorbidities and a low physical fitness.
- Conditions
- Morbid Obesity, Exercise, Bariatric Surgery
- Trial name
- NCT03975244
- Testing
- Exercise program
- Volunteers
- 60 people
- Sponsor
- Hospital General Universitario Elche
Diabetes Mellitus
Prevention of Postprandial Hyperglycemia by Acarbose May be a Promising Therapeutic Strategy for Reducing the Increased Risk for Cardiovascular Disease
The use of acarbose in impaired glucose tolerance (IGT) and type 2 diabetic subjects has been associated with a significant reduction of cardiovascular events.
- Trial name
- ABDOMEN (NCT01167231)
- Testing
- Acarbose (Glucobay, BAYG5421)
- Where
- Poland
- Volunteers
- 3,310 people
- Sponsor
- Bayer
Glucose Metabolism Disorders, Colon Cancer
COLONIC RESECTION FOR CANCER AS DIABETOGENIC RISK FACTOR
Colon cancer (CC) survivors have an increased risk of developing T2D. A recent study revealed that the surgical procedures per se may be causally involved. Hence, left-sided colon resections increased the risk of developing T2D.
- Conditions
- Glucose Metabolism Disorders, Colon Cancer, Surgery, Chemotherapy Effect
- Trial name
- COLECDIAB (NCT04649567)
- Where
- 2 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- Hvidovre University Hospital
Cardiovascular Diseases, Metabolic Syndrome X
Examining the Link Between Trace Elements and Cardiovascular Disease Risk Factors in Young Adults
Cardiovascular disease (CVD) affects millions of people in the United States; each year, more people die from CVD than from any other disease.
- Conditions
- Cardiovascular Diseases, Metabolic Syndrome X, Hypertension, Inflammation
- Trial name
- NCT00318734
- Where
- United States
- Volunteers
- 4,362 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
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