Clinical trials: Metabolic Risk Factors
Hypercholesterolemia, Hypertriglyceridemia
Beef in an Optimal Lean Diet (BOLD) Effects on Cardiovascular Disease (CVD) Risk
The study is designed to assess the effects of a heart-healthy diet that includes lean beef as the primary source of high quality protein on risk factors for cardiovascular disease.
- Trial name
- BOLD (NCT00937898)
- Testing
- BOLD+ Diet, BOLD diet
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Penn State University
Body Mass Index Quantitative Trait Locus 7 Disorder, Tangier Disease
Effect of High Protein Diet on Cardiovascular Diseases Risk Factors Among Overweight and Obese Children
The investigators aimed to determine the effects of HP diet on CVD risk factors among overweight and obese children.
- Trial name
- NCT01886482
- Testing
- nutrition intervention
- Where
- Iran
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Coronary Artery Disease, Diabetes
Cardiovascular Health and Text Messaging-Diabetes Mellitus (CHAT-DM) Study
The study is a two-arm, parallel, randomized clinical trial. The purpose of the study is to evaluate the effectiveness of automated mobile phone text message-based intervention for secondary prevention, including lifestyles…
- Trial name
- NCT02883842
- Testing
- Text messaging
- Where
- China
- Volunteers
- 502 people
- Sponsor
- China National Center for Cardiovascular Diseases
Carbohydrate, Hypoxia
Isolated and Combined Effect of a Low Carbohydrate Diet and Exercise in Hypoxia in Patients With Type 2 Diabetes
The purpose of this study is to determine the effects of isolated chronic exercise in hypoxia and combined exercise in hypoxia with a low carbohydrate diet on hypoxia-induced transcription factor (HIF1-α); glycaemic control and…
- Conditions
- Carbohydrate, Hypoxia, Exercise, Diabetes Mellitus, Type 2
- Trial name
- NCT05094505
- Testing
- Exercise in normoxia, Control diet, Exercise in hypoxia
- Where
- 2 sites in Portugal
- Volunteers
- 42 people
- Sponsor
- Universidade do Porto
Cardiovascular Risk Factor, Lipemia
Postprandial Monocyte Maturation and Vascular Dysfunction Following High-Fat Meals - Study 1
The purpose of this research study is to examine the effect of high-fat meals on the health of blood vessels. In addition, the study will examine how exercise/fitness/physical activity impacts blood vessels after consumption of a…
- Trial name
- NCT03958734
- Testing
- High-fat meal
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Stroke
Cardiovascular Effects of Treadmill Training With Post-stroke Functional Electrical Stimulation
Introduction: Stroke is one of the major causes of morbidity/mortality in the world and affected individuals, due to important (mainly motor) impairments, have their physical capacity to exercise reduced, a fact that aggravates…
- Trial name
- NCT05549141
- Testing
- treadmill gait training with gait facilitators, treadmill gait training not-associated with gait facilitators
- Where
- 2 sites in Brazil
- Volunteers
- 28 people
- Sponsor
- University of Sao Paulo
Cardiovascular Diseases, Diabetes Mellitus Type 2
"Screening for Change: Early Risk Detection and Integrated Prevention for Diabetes and Cardiovascular Diseases in the Marche Region"
This study aims to test the feasibility of a new systematic screening program to allow the early detection of individuals aged 50 years at risk of type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVDs) in the resident…
- Trial name
- JAC_AST (NCT07344701)
- Testing
- Screening program
- Where
- 2 sites in Italy
- Volunteers
- 2,951 people
- Sponsor
- Marche Region Regional Health Agency
Growth Hormone Deficiency, Cardiovascular Diseases
GH and Cardiovascular Risk Factors
Rationale: Abnormally low and high levels of insulin-like growth factor-I (IGF-I) are both associated with increased metabolic risk.
- Conditions
- Growth Hormone Deficiency, Cardiovascular Diseases, Metabolic Syndrome, Cognition
- Trial name
- NCT01877512
- Testing
- Change in daily dosage of Growth Hormone
- Where
- Netherlands
- Volunteers
- 32 people
- Sponsor
- Amsterdam UMC, location VUmc
Retinopathy, Nephropathy
Time To Complications Occurs in Diabetes
Diabetes causing serious complications is well known. In this study the aim is to follow 950 patients with diabetes for 15 years to study when, in who and how the diabetes complications occurs.
- Conditions
- Retinopathy, Nephropathy, Diabetic Neuropathy, Vascular Disease
- Trial name
- NCT00969956
- Where
- Sweden
- Volunteers
- 17 people
- Sponsor
- Karolinska Institutet
Type 2 Diabetes, Overweight
Effects of Caloric Restriction on Fetuin-A and Cardiovascular Risk Factors
The aim of this randomized controlled study was to evaluate the effects of CR on circulating fetuin-A levels in obese humans with type 2 diabetes based on monitoring energy intake and energy expenditure by daily activity.
- Trial name
- NCT01329822
- Testing
- Caloric restriction
- Where
- South Korea
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Korea University
Cardiovascular Diseases
Evaluating Electrocardiogram (ECG) Abnormalities From Young Adulthood Through Middle Age
An electrocardiogram (ECG) is a test that evaluates the electrical activity of the heart and can be used to detect heart problems.
- Trial name
- CARDIA ECG (NCT00556751)
- Where
- United States
- Volunteers
- 5,115 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Child Obesity
Childhood Obesity Risk Assessment Longitudinal Study
Childhood obesity is a major public health problem worldwide. Europe has a high prevalence of obesity, which is accentuated in Mediterranean countries.
- Trial name
- CORALS (NCT06317883)
- Where
- 8 sites in Spain
- Volunteers
- 1,508 people, healthy volunteers welcome
- Sponsor
- Consorcio Centro de Investigación Biomédica en Red (CIBER)
Diabetes Mellitus, Type 2
Effects of Legume Intake on Cardiovascular Risk Factors Among Adults at Risk for Diabetes
This randomized cross-over study was designed to investigate the effects of legume enriched diet consumption on cardiovascular risk factors among first degree relatives of diabetic patients.
- Trial name
- NCT01906099
- Testing
- nutritional intervention, life style modification
- Where
- Iran
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Diabetes, Dyslipidemia
Strategies to Maintain Cardiac Risk Control After Discharge From Cardiovascular Risk Reduction Clinic
The purpose of this study is to determine whether a combined behavioral and pharmacological intervention provided by a multidisciplinary team will further reduce LDL-C, smoking, BP and Hb-A1C in diabetic patients with A1c between…
- Conditions
- Diabetes, Dyslipidemia, Hypertension, Coronary Atherosclerosis
- Trial name
- NCT00358033
- Testing
- Counseling, Interactive Education, Group Support
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Providence VA Medical Center
Cardiovascular Risk Factors, Metabolic Risk Factors
Intervention Study to Prevent Obesity in Sedentary 8 Year Old Swedish Children
The purpose of this study is to study whether a targeted intervention can increase physical activity in inactive 8-yr old children and how it affects secondary measures such as metabolic- and cardiovascular risk factors and…
- Conditions
- Cardiovascular Risk Factors, Metabolic Risk Factors, Sedentary Lifestyle, Overweight
- Trial name
- STOPP-8 (NCT01087411)
- Testing
- Motivational Interviewing, Physical activity, Supplementation with fish liver oli capsules
- Where
- Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Metabolic Syndrome
Effect of Growth Hormone in Metabolic Syndrome
Investigating the effect of low dose growth hormone therapy on body fat composition, insulin sensitivity and metabolic profiles in middle-aged men with metabolic syndrome and low insulin-like growth factor (IGF-1) level.
- Trial name
- NCT00307411
- Testing
- Growth hormone
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Chinese University of Hong Kong
Smoking, Overweight
The Effect of a High Protein Diet Versus a Low Fat Diet on Body Weight After Smoking Cessation
The purpose of this study is to determine whether subjects following a high protein diet will gain less in weight after smoking cessation compared to subjects following a low fat diet due to the effects of protein on metabolic…
- Conditions
- Smoking, Overweight, Obesity
- Trial name
- NCT01069458
- Testing
- The high protein diet group and the low fat diet group
- Where
- Norway
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Cardiovascular Risk Factors
A Study of Different Types of Fatty Acid on Risk Factors for Heart Disease
Experimental elevation of non-esterified fatty acids (NEFA) impairs endothelial function and insulin sensitivity but the impact of NEFA composition is unknown.
- Trial name
- eFAIRE (NCT01351324)
- Testing
- Absence or presence of fish oil
- Where
- United Kingdom
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Reading
Metabolic Syndrome, PreDiabetes
Lean Beef Consumption and Insulin Sensitivity in Men and Women With Risk Factors for Diabetes
The objective of this trial is to compare the effects of a healthy, lean beef diet and an average American, United States Department of Agriculture (USDA) style diet, that is low in saturated fatty acids (SFA), on insulin…
- Trial name
- NCT03202680
- Testing
- USDA Style Diet, Lean Beef Diet
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Midwest Center for Metabolic and Cardiovascular Research
Obesity, Insulin Resistance
Effects of Obesity and Intensity of Exercise on Ghrelin Levels
This study is investigating the effect of different intensities of exercise on levels of the hormone, ghrelin. In addition, we will be examining the relationship between any exercise induced changes in ghrelin and insulin…
- Conditions
- Obesity, Insulin Resistance, Cardiovascular Risk Factor
- Trial name
- NCT04581980
- Testing
- Exercise
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Virginia
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