Clinical trials: Metabolic Risk Factors
Obesity, Overweight
Vitamin D Supplementation for the Prevention of Cardiovascular Risk
Hypovitaminosis D is highly prevalent in the general population, particularly in obese individuals. Besides being associated with obesity, vitamin D deficiency seems to be involved in the pathogenesis of insulin resistance and…
- Conditions
- Obesity, Overweight, Insulin Resistance
- Trial name
- NCT02020694
- Testing
- Vitamin D
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Obesity
Intermittent Eating on Sustaining Weight-loss in Obesity
Weight regain after weight loss is a major problem in the treatment of obesity. Two novel types of intermittent fasting recently have received more attention: the 5:2 diet and time-restricted eating (TRE).
- Trial name
- INTEREST (NCT05453617)
- Testing
- Time-restricted eating, The 5:2 diet
- Where
- China
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Cardiovascular Diseases, Diabetes Mellitus, Type 2
The Japan Diabetes Optimal Integrated Treatment Study for 3 Major Risk Factors of Cardiovascular Diseases
(Intervention study) The objective of the study is to confirm the superiority of the intensive therapy to the conventional therapy concerning the prevention of the incidence or exacerbation of vascular complications caused by…
- Trial name
- J-DOIT3 (NCT00300976)
- Testing
- Lifestyle consultation: weight control, diet, exercise
- Where
- Japan
- Volunteers
- 2,542 people
- Sponsor
- Japan Foundation for the Promotion of International Medical Research Cooperation
Polycystic Ovary Syndrome
Empagliflozin vs Metformin in PCOS
This a randomised open-label parallel study involving women with polycystic ovary syndrome (PCOS). The patients will be randomised either to metformin 1500mg or empagliflozin 25mg daily for three months.
- Trial name
- NCT03008551
- Testing
- Empagliflozin, Metformin
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Metabolic Syndrome Risk Factors, Overweight
Study of Effectiveness of Different Lifestyle Interventions for Health and Wellbeing
The purpose of this study is to examine the effectiveness and applicability of different interventions designed for enhancing overall wellbeing.
- Conditions
- Metabolic Syndrome Risk Factors, Overweight, Psychological Stress
- Trial name
- NCT01738256
- Testing
- Wellbeing intervention (ACT), Wellbeing intervention (Internet), No intervention
- Where
- 3 sites in Finland
- Volunteers
- 339 people
- Sponsor
- University of Jyvaskyla
Sodium Excess, Cardiovascular Risk Factor
A Short, Animated Storytelling Video to Increase Knowledge About Sodium Intake as a Cardiovascular Risk Factor
This study will evaluate the effect of a short, animated storytelling intervention video on sodium intake as a major risk factor for cardiovascular disease on immediate and medium-term retention of knowledge about the risks of…
- Conditions
- Sodium Excess, Cardiovascular Risk Factor, Education Entertainment Intervention, Short, Animated Storytelling
- Trial name
- NCT05735457
- Testing
- A short, animated storytelling video on dietary sodium
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University Hospital Freiburg
Metabolic Syndrome, Cardiovascular Diseases
Tart Cherry, Metabolic Syndrome, and Cardiovascular Risk
The hypothesis of this study is that the daily consumption of 480 ml tart cherry juice for twelve weeks will improve blood pressure and arterial stiffness by improving endothelial-mediated vasodilation and vascular sympathetic…
- Conditions
- Metabolic Syndrome, Cardiovascular Diseases, Diabetes
- Trial name
- NCT02154100
- Testing
- Tart Cherry
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Florida State University
Chronic Kidney Disease
Evaluation of Cardiovascular Risk Factors in Incident Dialysis Patients
To evaluate the relationships between bone mineral markers levels at dialysis start and vascular calcification progression during a 2 year follow up
- Trial name
- NCT02813642
- Testing
- Plasma osteoprotegerin level, Plasma fibroblast growth factor 23 level, Vascular calcification score
- Where
- 5 sites in France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Montpellier
Cardiovascular Risk Factor, Lipaemia
Effect of Lactose on Blood Lipids
This study aims to determine to what extent ingestion of free sugars influence postprandial triglyceridaemia in men and women.
- Conditions
- Cardiovascular Risk Factor, Lipaemia, Metabolic Disease
- Trial name
- NCT04924530
- Testing
- Maltodextrin, Sucrose, Lactose
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Bath
Cardiovascular Risk Factor, Cardiovascular Diseases
The Role of a Motion Sensor With Accompanying Web Application on Step Counts, Energy Balance, and Metabolic Markers in Nurses
The purpose of this prospective randomized controlled trial is to explore the role of a motion sensor with accompany web application on step counts, energy balance, and metabolic markers in nurses.
- Trial name
- WALK (NCT04524572)
- Testing
- Motion sensor
- Where
- Canada
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Cardiovascular Diseases, Metabolic Syndrome
Diets, Lipoproteins and Inflammation Markers
Systematic inflammation and lipid profiles are two major therapeutic targets for cardiovascular diseases. The effectiveness of vegan diet has been reported (doi: 10.3389/fnut.2022.807810).
- Conditions
- Cardiovascular Diseases, Metabolic Syndrome, Diet, Healthy, Vegan Diet
- Trial name
- NCT05423457
- Testing
- Vegan diet
- Where
- Taiwan
- Volunteers
- 21 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Risk Factors, MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
Risk of MASLD in Adults in Romania
This study aims to evaluate the presence of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) risk factors and estimate the probability of advanced liver disease in a Romanian cohort from the European Health…
- Trial name
- MASLD Ro (NCT06864845)
- Where
- 2 sites in Romania
- Volunteers
- 5,340 people, healthy volunteers welcome
- Sponsor
- Internist.Ro
Obesity, Overweight
The Food Intake Phenotype: Assessing Eating Behavior and Food Preferences as Risk Factors for Obesity
The prevalence of obesity in the United States has reached alarming proportions with 33% of adults over the age of 20 being overweight. Obesity is more than twice as prevalent, however, in the Pima Indians of Arizona.
- Conditions
- Obesity, Overweight, Overnutrition
- Trial name
- NCT00342732
- Where
- United States
- Volunteers
- 539 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Biochemically Recurrent Prostate Carcinoma, Metastatic Prostate Adenocarcinoma
Modifying Metabolic Syndrome and Cardiovascular Risk for Prostate Cancer Patients on ADT Using a Risk Factor Modification Program and Continuous Fitbit Monitoring
This phase II trial studies how well an exercise program and continuous Fitbit monitoring work for managing metabolic syndrome and cardiovascular disease risk in patients with prostate cancer that has spread to other places in…
- Conditions
- Biochemically Recurrent Prostate Carcinoma, Metastatic Prostate Adenocarcinoma, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8
- Trial name
- NCT05054296
- Testing
- Educational Intervention, Exercise Intervention, FitBit
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- M.D. Anderson Cancer Center
Abdominal Obesity
Effects of Weight Reduction on Sleep and Alertness in Long-distance Truck and Bus Drivers
The study is a year-long health-behaviour intervention in obese, male truck-drivers to lose weight moderately by 10%, using monthly individual counseling.
- Trial name
- SF-Truck (NCT00893646)
- Testing
- weight loss counseling
- Where
- 3 sites in Finland
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- UKK Institute
Hypertension, Overweight
The Effects of Aronia Juice Polyphenols on Cardiovascular Disease Risk
The existing scientific evidence from both in vitro and clinical trials supports the notion that polyphenols can modulate platelet function.
- Trial name
- AMARCord (NCT02800967)
- Testing
- Pure Aronia juice, Aronia juice-based beverage
- Where
- Serbia
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Metabolic Syndrome X, Diabetes Mellitus Type 2
Metabolic Syndrome and Related Diseases in Healthcare Workers
This study aims to investigate the incidence and prevalence of metabolic syndrome and metabolism-related diseases among healthcare workers, identify potential risk factors for these diseases, evaluate the control status of these…
- Conditions
- Metabolic Syndrome X, Diabetes Mellitus Type 2, Hypertension, Hyperlipidemia
- Trial name
- NCT06543706
- Where
- China
- Volunteers
- 7,432 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Cardiovascular Diseases, Diabetes Mellitus, Type 2
Evaluating a Web-Based Cardiovascular Disease Risk Factor Reduction Program Among American Indians
Cardiovascular disease (CVD) is a serious health concern for American Indians, but there have been few behaviorally based programs to lessen CVD risk among this population.
- Conditions
- Cardiovascular Diseases, Diabetes Mellitus, Type 2, Hypertension, Obesity
- Trial name
- NCT00608387
- Testing
- Chronic disease management Web-based software
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Black Hills Center for American Indian Health
Sedentary Lifestyle, Overweight and Obesity
The Effect of Frequency and Duration of Breaks in Sitting Time on Metabolic Cardiovascular Risk Factors
The primary aim of this study is to investigate the acute effect of the frequency and duration of breaks in sitting time on the metabolic risk factor profile.
- Conditions
- Sedentary Lifestyle, Overweight and Obesity, Metabolic Disease
- Trial name
- BPS2 (NCT02951624)
- Testing
- Control, Breaker, Prolonger
- Where
- Denmark
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Type 2 Diabetes, Chronic Disease
Prevention Strategies for Adolescents at Risk of Diabetes
The primary aim of PRE-STARt Phase 1 is to pragmatically evaluate and refine a risk assessment tool to identify those children with chronic disease risk factors (including Type 2 Diabetes).
- Trial name
- PRE-STARt (NCT02545140)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 634 people, healthy volunteers welcome
- Sponsor
- University Hospitals, Leicester
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