Clinical trials: Metabolic Risk Factors
Epiretinal Membrane
Prevalence and Risk Factors of Epiretinal Membrane in Diabetic and Non-diabetic Patients
Numerous terms have been used to describe epiretinal membrane (ERM): macular pucker, epimacular membrane, surface-wrinkling retinopathy, cellophane maculopathy and preretinal macular fibrosis.
- Trial name
- NCT03362580
- Testing
- Slit lamp examination, Undilated 7-field color fundus photography, Color scan
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Laurence Postelmans
Medication Adherence
Lifestyle, Self-medication and Use of Nutraceuticals in a Population of Italian and Spanish Students
University students are considered a population class with a high risk of malnutrition and/or obesity, metabolic and cardiovascular diseases, with a tendency to misuse drugs and self-medication.
- Trial name
- STANIS (NCT04099420)
- Testing
- Lifestyle counseling
- Where
- 3 sites in Italy, Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Maura Palmery
Glucose Intolerance, Diabetes Mellitus, Type 2
Lifestyle Interventions to Reduce Diabetes Risk
Type 2 diabetes is more frequent in Japanese Americans than in Japan or the U.S. non-Hispanic white population. This appears to be due to the effects of ''westernization'' to bring out metabolic changes that lead to diabetes.
- Trial name
- NCT00006162
- Testing
- exercise and diet
- Where
- United States
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Cardiovascular Risk Factor, Cardiovascular Diseases
The Role of a Motion Sensor With Accompanying Web Application on Step Counts, Energy Balance, and Metabolic Markers in Nurses
The purpose of this prospective randomized controlled trial is to explore the role of a motion sensor with accompany web application on step counts, energy balance, and metabolic markers in nurses.
- Trial name
- WALK (NCT04524572)
- Testing
- Motion sensor
- Where
- Canada
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Type II Diabetes Mellitus
Feasibility Trial in Urban Pakistan for Community Engagement in Preventing Type II Diabetes and Risk Factors
This project aims to adapt, implement, and evaluate PLA based intervention in urban Karachi, Pakistan for TIIDM prevention and control.
- Trial name
- EMPOWER-D (NCT06570057)
- Testing
- Participatory, learning and Action (PLA) Based intervention
- Where
- Pakistan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Baqai Institute of Diabetology and Endocrinology
Diabetes Mellitus, Type 2, Cognitive Dysfunction
Risk Factors for Type 2 Diabetes Mellitus With Cognitive Impairment: a Cohort Study
The aim of this study was to analyze the risk factors for the development of type 2 diabetes mellitus (T2DM) with mild cognitive impairment (MCI) and its pathogenesis associated with gut microbiota.
- Conditions
- Diabetes Mellitus, Type 2, Cognitive Dysfunction, Gut Microbiota
- Trial name
- NCT05728567
- Testing
- whether the participants had T2DM
- Volunteers
- 3,820 people
- Sponsor
- Peking University
Obesity, Cardiovascular Risk Factor
Hipoenergetic Effect of Diet Associated or Not With the Consumption of Coconut Flour in Women With Overweight
This study aimed to evaluate the effect of weight loss with diet combined coconut flour consumption improvement weight loss and reduction in glucose, cholesterol in obese women.
- Trial name
- NCT02152111
- Testing
- Coconut flour, Diet
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Metabolic Syndrome (MetS), Metabolic Syndrome Risk Factors
Effects and Mechanisms of Dietary Carbohydrate Intake and Quality on Glucose and Lipid Metabolism
This study aimed to explore the effects of quantity and quality of dietary carbohydrate intakes on glucose and lipid levels and metabolism, as well as gut microbiota by a randomized crossover controlled intervention trial.
- Trial name
- NCT07533513
- Testing
- Diet
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Cardiovascular Risk Factors, Insulin Resistance
Pilot Validation of the STELA Preventive Medicine Platform to Reduce Modifiable Health Risk Factors in Adults (CPM-STELA)
This study evaluates a comprehensive digital health platform called STELA, developed at the Center for Preventive Medicine (CPM) of AGEL Hospital Trinec-Podlesi in Czechia.
- Conditions
- Cardiovascular Risk Factors, Insulin Resistance, Obesity, Dyslipidemias
- Trial name
- CPM-STELA (NCT07551960)
- Testing
- STELA Digital Preventive Medicine Platform, Comprehensive Preventive Health Assessment
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nemocnice AGEL Trinec-Podlesi a.s.
Musculoskeletal Pain, Osteoarthritis
Integrated Healthy Lifestyle and Pain Care for People With Musculoskeletal Conditions Living in Rural Areas.
This study aims to compare the effects of an in-person physiotherapist-led lifestyle-focused pain care intervention with a virtual multidisciplinary lifestyle-focused pain care intervention on pain impact in people with…
- Conditions
- Musculoskeletal Pain, Osteoarthritis, Low Back Pain
- Trial name
- HeLP-R (NCT07173335)
- Testing
- In-person physiotherapist led integrated healthy lifestyle and pain care, Virtual multidisciplinary integrated healthy lifestyle and pain care
- Where
- 3 sites in Australia
- Volunteers
- 354 people
- Sponsor
- University of Sydney
Type 2 Diabetes, Cardiovascular Diseases
Pistachios Blood Sugar Control, Heart and Gut Health
A two-period randomized crossover study will be conducted to evaluate the effect of nighttime pistachio consumption (i.e., after dinner and before sleep) on fasting blood sugar levels, longer-term blood sugar control, and risk…
- Trial name
- NCT04056208
- Testing
- Pistachio, Usual care
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Penn State University
Bariatric Surgery
Glycemic Patterns After Bariatric Surgery and High Glycemic Variability and Hypoglycemia Unawareness Risk Factors
To study the glycemic patterns of patients undergoing bariatric surgery and what are the risk factors capable of predicting episodes of unnoticed hypoglycemia and high glycemic variability, evaluating patients who underwent…
- Trial name
- NCT05728320
- Testing
- Glucose monitoring with flash glucose monitor
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Metabolic Syndrome, Inflammation
The Effect of Probiotics on Low-grade Inflammation, Microbiota and Risk Factors for Metabolic Syndrome in Obese Children
Metabolic syndrome and thereby obesity is associated with low-grade systemic inflammation and it is likely that this is also the case in children (Ley et al., 2005).
- Conditions
- Metabolic Syndrome, Inflammation, Obesity
- Trial name
- NCT01020617
- Testing
- Ls-33
- Where
- Denmark
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Hypercholesterolemia
Effect of Plant Stanol Ester-Containing Spread on Estimated Cardiovascular Risk in Comparison to Mediterranean Diet
Since it is very difficult to have the real thing (Mediterranean diet) we need to find an alternative to reduce cardiovascular disease (CVD) risk in subjects with moderate hypercholesterolaemia (a major CVD risk factor) living in…
- Trial name
- NCT00793364
- Testing
- Stanol ester spread, Mediterranean Diet
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- Hellenic Atherosclerosis Society
Type 2 Diabetes Mellitus, Nutritional and Metabolic Diseases
Nutritional Prevention of Diabetes Mellitus Type 2
This study investigates the influence of red meat and fibers on glucose metabolism and body fat composition in subjects at increased risk for type 2 diabetes.
- Conditions
- Type 2 Diabetes Mellitus, Nutritional and Metabolic Diseases, Liver Fat, Insulin Sensitivity
- Trial name
- NUPREDM (NCT03231839)
- Testing
- Caloric restriction, no red meat, Increased fiber intake
- Where
- Germany
- Volunteers
- 132 people
- Sponsor
- University Hospital Tuebingen
Metabolic Syndrome
The Effect of Dietary Fat Modification on Risk Factors Associated With the Metabolic Syndrome
The LIPGENE Human Dietary Intervention Study, multi-centre, trans -European, single-blinded, randomised, controlled trial with two principal aims.
- Trial name
- NCT00429195
- Testing
- Dietary Fatty Acid Modification
- Where
- Ireland
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Metabolic Syndrome X, Exercise
The Effects of High-intensity Aerobic Training in Patients With Metabolic Syndrome
Background. The prevalence of metabolic syndrome (MetS) has been increasing, and its risk is positively correlated with age. Due to ageing society in Taiwan, how to treat metabolic syndrome and decrease the complications is an…
- Conditions
- Metabolic Syndrome X, Exercise, Physical Activity
- Trial name
- NCT02130336
- Testing
- Aerobic interval training, Continuous moderate-intensity exercise
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Disbiosis, Obesity
Limosilactobacillus Fermentum CRL 1446 - CONICET CASASCO
This research study aims to determine if a probiotic called Limosilactobacillus fermentum CRL 1446 can improve the health of people at risk for cardiovascular disease.
- Conditions
- Disbiosis, Obesity, Overweight (BMI > 25), Hypertension (Without Type 2 Diabetes Mellitus)
- Trial name
- NCT07530575
- Testing
- Limosilactobacillus fermentum 1446 CRL CONICET 2.20E+9 CFU
- Where
- 2 sites in Argentina
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- PINER Pastor Manfredi Winery
Fall, Fall Patients
Identifying Risk Factors for Falls in Patients With a High Risk of Fracture Using Connected Insoles (FeetMe Monitor® Device)
The objective of this study is to determine which gait parameters measured at home using e FeetMe® Insoles are associated with a risk for falls in a patient population suffering from osteoporosis and a higher with high risk of…
- Conditions
- Fall, Fall Patients, Osteoporosis
- Trial name
- FAIR (NCT05155761)
- Testing
- FeetMe® Monitor
- Where
- France
- Volunteers
- 250 people
- Sponsor
- FeetMe
Obesity
Weight Loss Effects on Heart and Blood Vessel Function in Obesity
Obesity is a growing epidemic and is associated with an increased risk of heart attack and stroke. The investigators know that obesity leads to abnormalities in how the blood vessels and the heart function and that these…
- Trial name
- NCT00782262
- Testing
- KicStart™
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
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