Clinical trials: Metabolic Risk Factors
Peritoneal Dialysis Patients
The Effects of Isoflavones on Cardiovascular and Bone Metabolism Markers in Peritoneal Dialysis Patients
The aim of this double-blind randomized clinical trial is to determine the effects of isoflavones on cardiovascular disease risk factors, bone metabolism markers, serum concentrations of fructoseamine and advanced glycated end…
- Trial name
- NCT03773029
- Testing
- soy isoflavone
- Where
- Iran
- Volunteers
- 47 people
- Sponsor
- National Nutrition and Food Technology Institute
Cardiovascular Risk Factors, Blood Pressure
Pharmacist Case Finding and Intervention for Vascular Prevention Trial
Heart disease is a common and serious medical condition which causes nearly one in every three deaths worldwide every year. The factors which increase people's risk for heart disease are well-known, but there needs to be more…
- Conditions
- Cardiovascular Risk Factors, Blood Pressure, Cardiovascular Disease, Diabetes
- Trial name
- PRxOACT (NCT06405880)
- Testing
- Pharmacist-led care pathway
- Where
- Canada
- Volunteers
- 1,003 people
- Sponsor
- University of Alberta
PreDiabetes
MEAL TIMING Study: Effect of Time-Restricted Feeding on 24-hour Glycemic Control, Blood Pressure, and Cardiovascular Disease Risk Factors in Adults With Prediabetes
One in three American adults have prediabetes, and up to 70% of adults with prediabetes eventually develop type 2 diabetes. With the high cost of treating diabetes, cost-effective approaches are needed to reduce the incidence of…
- Trial name
- NCT03504683
- Testing
- Early TRE, Mid-day TRE, Control Schedule
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- University of Alabama at Birmingham
Body Weight, Obesity
Meta Analysis of the Effect of a Low Glycemic Index Diet and Glycemic Load on Body Weight
A low glycemic index (GI) diet has been associated with improved glycemic control in type 2 diabetes patients and a reduced risk of cardiovascular disease (CVD).
- Conditions
- Body Weight, Obesity, Cardiovascular Diseases, Diabetes Mellitus, Type 2
- Trial name
- NCT02557022
- Testing
- GI and/or GL
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of Toronto
Metabolic Syndrome X
Walnut Intervention on Metabolic Syndrome (WIMS)
The purpose of this study is to determine whether a daily supplement of 30 grams of walnut is effective in the treatment of metabolic syndrome (MetS).
- Trial name
- WIMS (NCT00742742)
- Testing
- healthy life style education
- Where
- China
- Volunteers
- 189 people
- Sponsor
- Chinese Academy of Sciences
Intra-abdominal Fat, Metabolic Syndrome
Habitual Diet and Avocado Trial
The Habitual Diet and Avocado Trial will evaluate the effects of providing one avocado per day for recommended consumption over a 6 month period in a cohort of approximately 1000 free-living participants with increased waist…
- Conditions
- Intra-abdominal Fat, Metabolic Syndrome, High Cholesterol, Triglycerides High
- Trial name
- HAT (NCT03528031)
- Testing
- Intervention Daily Avocado
- Where
- 4 sites in United States
- Volunteers
- 1,008 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Heart Failure, Metabolic Cardiovascular Syndrome
Cardiometabolic evalUation REgistry of Heart Failure
This is a combined retrospective-prospective observational cohort study investigating the role of systemic and local cardiometabolic risk factors in cardiac structural/functional remodeling and clinical outcomes among heart…
- Conditions
- Heart Failure, Metabolic Cardiovascular Syndrome, Metabolic Diseases
- Trial name
- CURE-HF (NCT06939985)
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Ruijin Hospital
Diabetes Mellitus, Non Insulin Dependent Diabetes Mellitus
ED Diabetes Screening and Outpatient Care - Aim 3
This goal of this NIH funded R01 study is to identify risk factors for not being able to follow-up for a new diagnosis of diabetes in the emergency department and improve linkage of these newly diagnosed patients to appropriate…
- Trial name
- NCT05899023
- Testing
- Telehealth Bridge Visits, Standard of Care
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- NYU Langone Health
Atherosclerosis, Cardiovascular Risk Factor
Early Vascular Ageing in the YOUth
This is a single-center observational study on adolescents to determine predictors of the early steps of the formation of atherosclerosis and to quantify their influence on Intima-Media-Thickness of the carotid artery and the…
- Conditions
- Atherosclerosis, Cardiovascular Risk Factor, Cardiovascular Diseases, Cardiovascular Pathology
- Trial name
- EVA4YOU (NCT04598685)
- Where
- Austria
- Volunteers
- 1,517 people, healthy volunteers welcome
- Sponsor
- VASCage GmbH
Hypoparathyroidism
Predicting Risk Factors of Postoperative Hypocalcemia After Total Thyroidectomy
With increasing economic pressures to shorten the length of hospital stay, there has been much recent interest in studying risk factors for the development of postoperative hypocalcemia.
- Trial name
- NCT04372225
- Testing
- analysis of hypocalcemia
- Where
- France
- Volunteers
- 477 people, healthy volunteers welcome
- Sponsor
- Aix Marseille Université
Cardiovascular Disease, Type 2 Diabetes
Effects of Pistachios on Cardiovascular Responses to Stress in Type 2 Diabetes
This study is investigating the effects of three different diets, including a diet with pistachios, on cardiovascular disease risk markers in people with type 2 diabetes.
- Trial name
- Pistachio (NCT00956735)
- Testing
- Pistachio
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Penn State University
Cardiovascular Risk Factors, Insulin Resistance
Ice Cream Enriched With Cimarrón Bean Extrudate and Cardiovascular Risk in Adults
The goal of this clinical trial is to evaluate the chronic effects of consuming a functional ice cream enriched with Cimarrón bean (Phaseolus vulgaris local variety Cimarrón) extrudate in adults with at least one cardiovascular…
- Conditions
- Cardiovascular Risk Factors, Insulin Resistance, Overweight (BMI > 25)
- Trial name
- ICE-CBE-CARD (NCT07076563)
- Testing
- Functional Ice Cream with Cimarrón Bean Extrudate
- Where
- Chile
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Talca
Acute Pancreatitis (AP), Diabetes Mellitus
Hyperglycemia and Acute Pancreatitis
The goal of this observational study is to learn about post-acute pancreatitis diabetes mellitus (PPDM-A). The main questions it aims to answer are: 1. What are the clinical characteristics of PPDM-A? 2.
- Trial name
- NCT06590233
- Volunteers
- 4,500 people
- Sponsor
- Shanghai Changzheng Hospital
Sarcopenic Obesity, Diabetes
Sarcopenic Obesity in the Elderly
Ageing is associated with progressive and generalized loss of muscle mass and muscle function, also known as Sarcopenia. Increasingly, obesity has become a compounding factor in ageing-related sarcopenia.
- Trial name
- NCT06083909
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Obesity, Weight Loss
Lifestyle Intervention in Overweight Women
The Exercise and Obesity Health Promotion (PESO) program is a randomized controlled trial designed to analyze the effects of a lifestyle intervention in weight management and health-related parameters of overweight and obese…
- Conditions
- Obesity, Weight Loss, Lifestyle, Sedentary, Physical Activity
- Trial name
- PESO (NCT03823898)
- Testing
- Supervised exercise, Lifestyle intervention from baseline to 4 months, Monthly behavioral sessions
- Where
- Portugal
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Obesity
A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety in People With Overweight or Obesity (SYNCHRONIZE™ - CVOT)
This study is open to adults who are at least 18 years old and have a body mass index (BMI) of 27 kg/m2 or more. People can take part if they have cardiovascular or chronic kidney disease.
- Trial name
- NCT06077864
- Testing
- survodutide
- Where
- 542 sites in United States, Argentina and 33 more
- Volunteers
- 5,530 people
- Sponsor
- Boehringer Ingelheim
Diabetes Mellitus, Type 2, Hypertension
Olive Leaf Extracts in the Control of Cardiovascular Risk
This study will be carried out in 2 emergency departments (at the exit of the emergency room) and 2 external consultations (endocrinology of the CHU FB Monastir and diabetology consultation, Jemmal hospital).
- Trial name
- Atherolive (NCT05297110)
- Testing
- atherolive
- Where
- Tunisia
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Monastir
Cardiovascular Disease Prevention, Cardiometabolic Diseases
Preventative Screening and Health Coaching in a Food Insecure Population
The goal of this longitudinal study is to investigate the role of virtual health coaching on mitigation of cardiometabolic disease risk in an underserved, food insecure population.
- Conditions
- Cardiovascular Disease Prevention, Cardiometabolic Diseases, Cardiovascular Risk Factor, Cardiovascular Risk Score
- Trial name
- HEALTHCOACH (NCT06907524)
- Testing
- Longitudinal, Individualized Health Coaching
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Rush University Medical Center
Obesity & Overweight, Weight Loss
GLP-1 Medication & Behavioral Health Programs on Weight & Metabolic Outcomes: FLOURISH and THRIVE Prospective Cohort Study
This research program includes two coordinated prospective studies (FLOURISH and THRIVE) evaluating the real-world effectiveness of Noom's digital health programs on weight, cardiometabolic biomarkers, physiological health…
- Conditions
- Obesity & Overweight, Weight Loss, Preventative Health, Body Weight
- Trial name
- FLOURISH (NCT07588984)
- Testing
- Noom Weight, Free Tier, Education-only control
- Where
- United States
- Volunteers
- 2,310 people
- Sponsor
- Noom Inc.
Work Related Stress, Metabolic Syndrome
Effects of 10 Weeks of Lifestyle Coaching on Cardiometabolic Risk Factors, Workability and Subjective Wellbeing
The main purpose of this study is to understand the impact of lifestyle coaching on the risk of future cardiometabolic disease, workability and self-assessed wellbeing.
- Conditions
- Work Related Stress, Metabolic Syndrome, Lipid Metabolism Disorders, Lifestyle Risk Reduction
- Trial name
- NCT04633876
- Testing
- Individual coaching, Group coaching, Control group
- Where
- Finland
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Aava Medical
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