Clinical trials: Metabolic Risk Factors
Obesity, Smoking
Africa and Middle East Cardiovascular Epidemiological Study
This is a cross-sectional, epidemiological study to determine the prevalence of cardiovascular risk factors such as obesity, smoking, dyslipidemia, diabetes mellitus and hypertension in patients attending General Practice clinics…
- Conditions
- Obesity, Smoking, Dyslipidemia, Diabetes Mellitus
- Trial name
- ACE (NCT01243138)
- Where
- 73 sites in Algeria, Cameroon and 12 more
- Volunteers
- 4,386 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Cardiovascular Risk Factor, Cardiovascular Diseases
Study of Long-Term Efficacy and Safety of LIB003 in CVD or High Risk for CVD Patients Needing Further LDL-C Reduction
This study is to assess LDL-C reductions at Week 52 with monthly (Q4W [≤31 days]) dosing of LIB003 (lerodalcibep) 300 mg administered subcutaneously (SC) compared to placebo in patients with CVD, or at high risk for CVD, on a…
- Conditions
- Cardiovascular Risk Factor, Cardiovascular Diseases, Cardiovascular Stroke, Hypercholesterolemia
- Trial name
- LIBerate-HR (NCT04806893)
- Testing
- lerodalcibep
- Where
- 6 sites in United States, India and 1 more
- Volunteers
- 900 people
- Sponsor
- LIB Therapeutics LLC
Psoriasis, Atopic Dermatitis
Impact of the Severity of Pediatric Psoriasis on Childhood Body Mass Index
The object of this research study is to examine these associations in children as very little is known about psoriasis and cardiovascular risk factors in the pediatric population.
- Trial name
- NCT00879944
- Testing
- Blood pressure, Height, Weight
- Where
- 14 sites in United States, Canada and 4 more
- Volunteers
- 409 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Coronary Artery Disease, Percutaneous Coronary Intervention
Evaluation of Novel Risk Factors and Clinical Outcomes of Acute Myocardial Infarction
The aim of this study is to investigate the potential novel risk factors for acute myocardial infarction. Predictors of poor outcomes will be also evaluated.
- Conditions
- Coronary Artery Disease, Percutaneous Coronary Intervention, Acute Myocardial Infarction
- Trial name
- NCT02641184
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Zhejiang Provincial People's Hospital
Diabetes Mellitus, Type 2, Liver Fibrosis
Effect of an Early Time Restricted Eating Mediterranean Diet Compared to Naltrexone/Bupropion on Liver Fibrosis in People With Cardiometabolic Risk Factors in a Hospital Outpatient Clinic (MEDFAST-study)
In the Netherlands, there are many people with cardiometabolic diseases. More than half of these people also have fatty liver. This is a build-up of fat in the liver (steatosis) and can lead to long-term scarring (fibrosis) and…
- Conditions
- Diabetes Mellitus, Type 2, Liver Fibrosis, Liver Steatoses, Hepatic Steatosis
- Trial name
- MEDFAST (NCT06845345)
- Testing
- early time restricted Mediterranean diet, Mysimba
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- Carmen Dietvorst
Psoriasis, Psoriatic Arthritis (PsA)
Ten-Year Biologic Drug Survival in Psoriasis: Role of Genetic and Cardiometabolic Predictors
This retrospective observational study aims to evaluate the long-term survival of biologic therapies in adult patients with moderate-to-severe cutaneous psoriasis, with or without psoriatic arthritis, over a period of up to 10…
- Conditions
- Psoriasis, Psoriatic Arthritis (PsA), Cardiovascular Risk Factors, Metabolic Syndrome (MetS)
- Trial name
- GENBIOPSO (NCT07041112)
- Testing
- Biologic therapy for psoriasis
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Juan Ruano Ruiz
HIV-1-infection, Coronary Microvascular Dysfunction
Improving Coronary Vascular Health in Women
Women with HIV have an increased risk of having a myocardial infarction (heart attack) as compared to women without HIV. One of the mechanisms underlying the increased risk of myocardial infarction among women with HIV may…
- Conditions
- HIV-1-infection, Coronary Microvascular Dysfunction, Metabolic Disease
- Trial name
- INFORM_2 (NCT06843902)
- Testing
- Health Education, Subspecialty clinic referral
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Massachusetts General Hospital
Healthy, Impaired Glucose Tolerance
Effects of an Intermittent Fasting and Dietary Supplement Regimen on Glycemic Variability
The purpose of this study is to determine the short-term effect of a nutritional program consisting of a yerba mate supplement, fiber supplement, and intermittent fasting on glycemic variability in men and women with risk factors…
- Trial name
- NCT05493553
- Testing
- Dietary supplement regimen, Dietary supplement and intermittent fasting regimen
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Unicity International, Inc.
Epilepsy
Impact of Eslicarbazepine Acetate on Lipid Metabolism and Cardiovascular Risk Factors
Knowing the impact that the use of ESL as adjunctive treatment of partial epilepsy has on cardiovascular risk factors measured by biochemical and ultrasound parameters compared with enzyme-inducing AEDs.
- Trial name
- NCT02573272
- Testing
- eslicarbacepine
- Where
- Spain
- Volunteers
- 204 people
- Sponsor
- Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud
Kidney Stone
Metabolic Risk Factors and Stones Composition in Adult Kidney Stone Formers
Within the CHU Brugmann hospital, a multidisciplinary Renal Lithiasis and Mineral Metabolism clinic has been inaugurated in 2017.
- Trial name
- NCT04243772
- Testing
- Data extraction
- Where
- Belgium
- Volunteers
- 350 people
- Sponsor
- Agnieszka Pozdzik
Hypertension, Resistant to Conventional Therapy
Renal Sympathetic Denervation and Potential Effects on Glucose Metabolism and Cardiovascular Risk-Factors
The Re-Shape CV-Risk Study is a clinical study where renal adrenergic denervation (RDN) is done in high risk patients with treatment-resistant hypertension.
- Trial name
- Re-Shape (NCT01630928)
- Testing
- Renal sympathetic denervation
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- University Hospital of North Norway
Obesity, Atherosclerosis
Effect of Pyramidal Training on Selected Risk Factors of Atherosclerosis
The study will be conducted on fifty women with central obesity. Their ages will be from 30-40 years old. They will be selected from Al Hayat specialized Hospital in Cairo, Egypt and The participants will be randomly assigned…
- Trial name
- NCT06077552
- Testing
- pyramidal training by treadmill
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Stroke, Osteoporosis
Assessment and Comparison of Osteoporosis Risk Factors After Stroke
The aim of this study is to evaluate the effects of stroke and associated clinical, functional, nutritional, and muscular factors, including handgrip strength, on bone mineral density and osteoporosis by comparing patients with…
- Trial name
- NCT07228611
- Testing
- Bone Mineral Density
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Metabolic Syndrome, Sleeping Disorders
Effects of Nattokinase on Cardiovascular Risk, Gut Microbiota, Sleep, and Cognition in Metabolic Syndrome With Sleep Disorders.
Nattokinase has been confirmed by many experiments to have a thrombolytic effect, but there are currently very few studies on nattokinase's effect on gut microbiota, sleeping status, and age-related cognitive function.
- Trial name
- NCT07229521
- Testing
- Nattokinase
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taipei Medical University
Cardiovascular Risk Factors, Metabolic Risk Factors
Intervention Study to Prevent Obesity in Sedentary 8 Year Old Swedish Children
The purpose of this study is to study whether a targeted intervention can increase physical activity in inactive 8-yr old children and how it affects secondary measures such as metabolic- and cardiovascular risk factors and…
- Conditions
- Cardiovascular Risk Factors, Metabolic Risk Factors, Sedentary Lifestyle, Overweight
- Trial name
- STOPP-8 (NCT01087411)
- Testing
- Motivational Interviewing, Physical activity, Supplementation with fish liver oli capsules
- Where
- Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Cardiovascular Risk Factors
Cocoa Extract-enriched Meals and Cardiovascular Risk in Older Population
Obesity prevalence in elderly populations has increased in the last years, and the reduction of overweight and obesity is a priority target in populations of all age ranges worldwide.
- Trial name
- NCT01596309
- Testing
- Cocoa extract
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Hypertension, Diabetes Mellitus
Community Based Multiple Risk Factors Intervention Strategy
Randomized controlled trial of CORFIS Programme. The study objectives are as follows: 1. To determine the efficacy of a community based multiple risk factors interventional strategy (CORFIS) for a treatment period of 6 months in…
- Conditions
- Hypertension, Diabetes Mellitus, Hyperlipidemia
- Trial name
- CORFIS (NCT00490672)
- Testing
- No Active Intervention., Community Based Multiple Risk Factor Intervention Strategies
- Where
- 78 sites in Malaysia
- Volunteers
- 770 people
- Sponsor
- Ministry of Health, Malaysia
Obesity, Metabolically Benign
High-intensity Interval Training in Overweight/Obese
Purpose: The purpose of this study would be to evaluate the effects of interval training on cardiovascular health, lipid profile and body composition in overweight and obese men and women.
- Trial name
- NCT02444377
- Testing
- Interval training
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Cognitive Function 1, Social, Mental Health Wellness 1
Effects of an Exercise Program on Cognition and Brain in Overweight/Obese Preadolescent Children
The ActiveBrains project aims to examine whether a 5-months physical exercise program has benefits on cognition and brain, as well as on selected physical and mental health outcomes in preadolescent overweight/obese children.
- Conditions
- Cognitive Function 1, Social, Mental Health Wellness 1, Obesity, Overweight
- Trial name
- ActiveBrains (NCT02295072)
- Testing
- A 5-months physical exercise-based program
- Volunteers
- 110 people
- Sponsor
- Universidad de Granada
Gestational Diabetes Mellitus (GDM)
Tianjin Gestational Diabetes Prevention Program (TGDPP)
A total of 1,180 women diagnosed with Gestational Diabetes Mellitus (GDM) from 2005 to 2009 and their children have and continues to be randomly assigned to either the intervention group or the control group.
- Trial name
- GDM (NCT01554358)
- Testing
- Lifestyle intervention
- Where
- China
- Volunteers
- 2,526 people, healthy volunteers welcome
- Sponsor
- Tianjin Women and Children's Health Center
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