Clinical trials: Metabolic Risk Factors
Obesity, Dysglycemia
Secular Trends in the Prevalence of Cardiometabolic Risk Factors Among Teenage School Children in Urban South India
The prevalence of cardiometabolic risk is high among South Asians which manifests itself at an early age. Studies have reported that unhealthy food choices, inadequate physical activity and lack of awareness on healthy lifestyle…
- Conditions
- Obesity, Dysglycemia, Dyslipidemias, Hypertension
- Trial name
- NCT04015726
- Where
- India
- Volunteers
- 2,815 people, healthy volunteers welcome
- Sponsor
- India Diabetes Research Foundation & Dr. A. Ramachandran's Diabetes Hospitals
Obesity, Atherosclerosis
Endothelial Dysfunction in Obese Children
The purpose of this study is to objectify the effect of diet and exercise on early markers of atherosclerosis in obese children.
- Trial name
- EDOC (NCT01461226)
- Testing
- Exercise training, Usual care
- Where
- 3 sites in Belgium
- Volunteers
- 61 people
- Sponsor
- University Hospital, Antwerp
Diabetes Mellitus, Type 2, Catheterization, Peripheral
Incidence of Complications of Peripheral Venous Access in the Type 2 Diabetic Population
Diabetes Mellitus type 2 (T2DM) is one of the most frequent metabolic diseases worldwide. It is expected that in 2035 around 600 million people will suffer from the disease.
- Conditions
- Diabetes Mellitus, Type 2, Catheterization, Peripheral, Upper Extremity Deep Vein Thrombosis, Catheter-Related Infections
- Trial name
- NCT04499638
- Testing
- Peripheral vascular catheters
- Where
- Spain
- Volunteers
- 350 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Chronic Disease, Obesity
Evaluation of the Impact of a Sugar-Sweetened Beverage Tax in Chile
The purpose of this study is to evaluate formally the short term impacts of the tax policy applied to Sugar-Sweetened Beverages (SSBs) in Chile.
- Trial name
- NCT02926001
- Volunteers
- 2,836 people, healthy volunteers welcome
- Sponsor
- Marc Suhrcke
Polycystic Ovary Syndrome
Effect of Vitamin D on Hormonal, Metabolic and Cardiovascular Risk Factors in Patients With Polycystic Ovary Syndrome
This is a double blind randomised placebo-controlled study involving women with polycystic ovary syndrome (PCOS). The patients will be randomised either to Vitamin D 3200 IU or placebo for three months.
- Trial name
- NCT02513381
- Testing
- Vitamin D3, 3200IU
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Weight Loss
Evaluation of Efficacy of a Cashew Apple Extract on Weight Management and Associated Metabolic Risk Factors in Overweight/Obese Volunteers
The purpose of this study is to assess the efficacy and safety of a cashew apple extract on weight management and associated metabolic risk factors in overweight/obese volunteers, versus placebo, after 12 weeks of treatment.
- Trial name
- NCT02493140
- Testing
- Cashew apple extract (Cashewin)
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Dialpha
Metabolic Syndrome
Water Beverage Intervention Trial for Reducing Risk Factors of Metabolic Syndrome in Young Mexican Free Living Women
Research Question: Does replacing Sugar Sweetened (SS) beverages with water consumption promote a decrease in triglycerides blood levels over 9 months in overweight women? The primary outcome variable is the triglycerides blood…
- Trial name
- NCT01245010
- Testing
- Water, Education
- Where
- Mexico
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Mexican National Institute of Public Health
Atherosclerosis, Cardiovascular Diseases
Risk Factors for Atherogenesis in Type 1 Diabetes
To determine risk factors for atherogenesis in Type 1 diabetes.
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Diabetes Mellitus, Insulin-dependent, Heart Diseases
- Trial name
- NCT00035750
- Sponsor
- University of Wisconsin, Madison
Diabetic Ketoacidosis, Acute Kidney Injury
Risk Factors and Outcomes of Acute Kidney Injury in Patients With Diabetic Ketoacidosis at Sohag University Hospital.
Diabetic ketoacidosis (DKA), a severe complication of diabetes mellitus (DM), is the leading cause of hospitalization, morbidity and mortality in patients with DM (1).
- Trial name
- NCT05867797
- Volunteers
- 100 people
- Sponsor
- Sohag University
Type 2 Diabetes, Cardiovascular Disease
Study of TAK-875 in Adults With Type 2 Diabetes and Cardiovascular Disease or Risk Factors for Cardiovascular Disease
The purpose of this study is to demonstrate no excess risk of cardiovascular (CV) composite events exists following long term treatment with TAK-875 compared with placebo.
- Trial name
- NCT01609582
- Testing
- TAK-875
- Where
- 584 sites in United States, Argentina and 30 more
- Volunteers
- 3,207 people
- Sponsor
- Takeda
Sedentary Lifestyle, Overweight and Obesity
The Effect of Frequency and Duration of Breaks in Sitting Time on Metabolic Cardiovascular Risk Factors
The primary aim of this study is to investigate the acute effect of the frequency and duration of breaks in sitting time on the metabolic risk factor profile.
- Conditions
- Sedentary Lifestyle, Overweight and Obesity, Metabolic Disease
- Trial name
- BPS2 (NCT02951624)
- Testing
- Control, Breaker, Prolonger
- Where
- Denmark
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cardiovascular Diseases
Effect of Exercise or Metformin on Nocturnal Blood Pressure and Other Risk Factors for CVD Among Obese Adolescents
The objective is to, among obese adolescents, study impact of regular physical activity or metformin therapy on nocturnal blood pressure and related cardiovascular disease risk factors.
- Trial name
- NCT00889876
- Testing
- Metformin group, Exercise
- Where
- Sweden
- Volunteers
- 26 people
- Sponsor
- Maria Sandberg Westerstahl
Pancreatic Cancer, Surgery
Pancreatic Cancer and Diabetes Mellitus
The goal of this observational study is to learn about post-surgery of pancreatic cancer diabetes mellitus.The main questions it aims to answer are: 1.
- Conditions
- Pancreatic Cancer, Surgery, Diabetes Mellitus
- Trial name
- NCT06585072
- Testing
- All enrolled subjects completed dynamic blood glucose monitoring to obtain continuous peripheral blood glucose data.
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Shanghai Changzheng Hospital
Heart Failure Risk Factors in Healthy Individuals
Cleveland Heart and Metabolic Prevention Study
The purpose of this research study is to investigate the role of chemical reactions, such as inflammation and oxidation, in the cause of cardiac dysfunction (the heart does not function properly).
- Trial name
- CHAMPS (NCT03012022)
- Where
- United States
- Volunteers
- 1,208 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Psoriasis, Cardiovascular Diseases
The Influence of Adalimumab on Cardiovascular and Metabolic Risk in Psoriasis
Psoriasis vulgaris is no longer considered as a chronic inflammatory disease restricted to the skin. Evidence has accumulated in the past that psoriasis is a chronic inflammatory systemic disease.
- Conditions
- Psoriasis, Cardiovascular Diseases, Diabetes Mellitus, Type 2
- Trial name
- CASTIP (NCT01088165)
- Testing
- Adalimumab treatment arm, Fumaric acid esters treatment group, Narrow band UVB radiation
- Where
- Austria
- Volunteers
- 66 people
- Sponsor
- Medical University of Vienna
Obesity, Metabolic Disease
Behavioral Plant-Based Dietary Intervention in Latinos
The Aims of this study are 1) to develop a traditional plant-based diet that is palatable and acceptable to the Latino population and which contains the appropriate calorie and macronutrient composition needed to lose weight and…
- Trial name
- SB Pilot (NCT05444595)
- Testing
- Behavioral plant-based dietary intervention, Standard care
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Type 2 Diabetes
Nationwide Assessment of Cardiovascular Risk Factors: in Chinese Patients With Type 2 Diabetes
The objective of this study is to evaluate the level of control of cardiovascular disease risk factors, including blood pressure, blood lipid, and blood glucose, in out patients with type 2 DM in 6 representative regions in…
- Trial name
- 3B (NCT01128205)
- Where
- China
- Volunteers
- 25,000 people
- Sponsor
- China Cardiometabolic Registries
Cholesterol, Elevated, Diabetes Mellitus
Community Intervention to Improve CVD Risk Factor Control in Young American Indians
American Indians are more likely to die from heart disease compared to other people in the United States. High levels of fat (lipids) and sugar (glucose) in the blood are related to heart disease.
- Trial name
- CIRCLE (NCT06230705)
- Testing
- Guided management, Self management
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- University of Oklahoma
Diabetes
Diabetes Outcomes and Unmet Resources
This study will refine and test the effectiveness of CareAvenue, an automated e-health tool that informs and activates patients with uncontrolled diabetes to take steps in accessing resources and engaging in self-care.
- Trial name
- NCT03950973
- Testing
- CareAvenue, Guest Assistance Program
- Where
- United States
- Volunteers
- 667 people
- Sponsor
- University of Michigan
Coronary Artery Disease, Non-Obstructive Coronary Atherosclerosis
VIsualization of Coronary Artery Disease for Modification of RISK Factors
The VICAD-RISK study assesses if visualization of coronary CT angiography (CTA) images in participants with non-obstructive coronary artery disease will improve LDL lowering, reduce reporting of side effects by cholesterol…
- Trial name
- VICAD-RISK (NCT06413641)
- Testing
- Follow up at general practice, Consultation, Visualization of CTA images
- Where
- 5 sites in Denmark
- Volunteers
- 273 people
- Sponsor
- Aarhus University Hospital
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