Clinical trials: Metabolic Risk Factors
Polycystic Ovary Syndrome
Oral Contraceptive and Cardiovascular Risk in PCOS
Oral contraceptive therapy is routinely used for the treatment of menstrual disturbances of patients with polycystic ovary syndrome (PCOS).
- Trial name
- NCT00593294
- Testing
- Physical exercise, OC - Drospirenone plus Ethynylestradiol, Vitamin, polyvitamins tablets
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Federico II University
Obesity, Childhood, Cardiac Disease
Chronotropic Incompetence During Exercise Testing in Obese Adolescents
In adolescents with obesity cardiopulmonary exercise testing (CPET) has become an important clinical examination providing valuable information with regard to the integrative exercise responses, including the pulmonary…
- Conditions
- Obesity, Childhood, Cardiac Disease, Cardiovascular Risk Factor
- Trial name
- NCT04185753
- Testing
- The prevalence of chronotropic incompetence during maximal cardiopulmonary exercise testing
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Hasselt University
Hypophosphatemia, Bronchiolitis
Hypophosphatemia and Bronchiolitis
Bronchiolitis is a major public health problem and the leading cause of paediatric intensive care unit admission in infants. Hypophosphatemia is common in adult intensive care units and was associated with an increase of the…
- Trial name
- NCT04814641
- Testing
- hypophosphatemia occurrence in infants with severe bronchiolitis admitted in a pediatric intensive care unit
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Hospices Civils de Lyon
Multiple Myeloma, Amyloidosis Cardiac
The Diagnostic Pattern and Prognosis of Multiple Myeloma Patients With Myocardial Amyloidosis Were Evaluated by NMR Based Metabolomics
In this clinical study, a single-center retrospective cohort study was used to explore the clinical characteristics and risk factors of patients with multiple myeloma myocardial amyloidosis.
- Trial name
- NCT05718401
- Testing
- NMR
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Hyperglycemia, Mental Disorder
Explore the Risk Factors for Antenatal Mental Disorders in Pregnant Women With Hyperglycemia
This study aims to investigate the current situation and risk factors of adverse mental disorders in pregnant women with hyperglycemia. it could include any of the following: 18-45 years old pregnant women with hyperglycemia.
- Conditions
- Hyperglycemia, Mental Disorder, Pregnancy Complications
- Trial name
- NCT07003503
- Volunteers
- 635 people, healthy volunteers welcome
- Sponsor
- Shenzhen Hospital of Southern Medical University
Complications
Incidence and Risk Factors of Ocular Complications Among Patients With Homocystinuria
Background: Cysteine beta-synthase (CBS) deficiency, often known as classic homocystinuria (HCU), is an uncommon inborn mistake in methionine metabolism.
- Trial name
- NCT06545305
- Testing
- Lensectomy and vitrectomy
- Where
- Saudi Arabia
- Volunteers
- 6 people
- Sponsor
- King Fahad Armed Forces Hospital
High Blood Pressure, Hypercholesterolemia
Cardiovascular Risk Factors And Intensive Dietary Counselling
The Intensive Dietary Counselling (IDC) intervention is a prevention and health promotion activity. It is being implemented by the Andalusian Health Service to reinforce basic intervention advice on healthy diet and exercise.
- Conditions
- High Blood Pressure, Hypercholesterolemia, Tobacco Smoking
- Trial name
- NCT02173600
- Testing
- Group-level Intensive dietary Counselling, Individual-level Intensive Dietary Counselling
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Andalusian Regional Ministry of Health
Cardiovascular Diseases, Cardiovascular Risk Factor
Digital Nudges to Improve Heart Health Actions After Community Screening in Malaysia (NADI-MyHeartRisk)
This is a pragmatic, risk-stratified, individually randomized controlled trial testing whether personalised WhatsApp-based digital behavioural nudges can improve completion of cardiovascular preventive actions after community…
- Trial name
- NADI-MHR (NCT07879144)
- Testing
- Personalised Digital Behavioural Nudges (NADI-MyHeartRisk Enhanced Pathway)
- Where
- 2 sites in Malaysia
- Volunteers
- 6,588 people, healthy volunteers welcome
- Sponsor
- Cardiovascular Advancement and Research Excellence Institute
Cardiovascular Diseases, Overweight
Enhancing Mental and Physical Health of Women Veterans
Women Veterans are the fastest growing segment of VA users. This dramatic growth has created challenges for VA to ensure that appropriate services are available to meet women Veterans' needs, and that they will want and be able…
- Conditions
- Cardiovascular Diseases, Overweight, Obesity, Smoking
- Trial name
- EMPOWER (NCT05050266)
- Testing
- EBQI, REP
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Hyperuricemia, Diet, Healthy
Vegan Diet, Amla Fruits and Uric Acid
This is an intervention study aiming to test the effectiveness of a vegan diet, My Plate with low purine choices, and amla fruits on uric acid and other cardiometabolic risk factors in individuals with high serum uric acid levels.
- Conditions
- Hyperuricemia, Diet, Healthy, Cardiometabolic Syndrome
- Trial name
- NCT04801745
- Testing
- Healthy vegan diet, My Plate - Low Purine, Amla fruits
- Where
- Taiwan
- Volunteers
- 102 people
- Sponsor
- Fu Jen Catholic University
Retinopathy, Nephropathy
Time To Complications Occurs in Diabetes
Diabetes causing serious complications is well known. In this study the aim is to follow 950 patients with diabetes for 15 years to study when, in who and how the diabetes complications occurs.
- Conditions
- Retinopathy, Nephropathy, Diabetic Neuropathy, Vascular Disease
- Trial name
- NCT00969956
- Where
- Sweden
- Volunteers
- 17 people
- Sponsor
- Karolinska Institutet
Type 1 Diabetes
Risk Factors of Metabolic Control in Children and Adolescents With Type 1 Diabetes
Background: Type 1 diabetes is one of the most common chronic illnesses among children and adolescents. Although, intensive medical care is provided for these patients, some of them have poor metabolic control.
- Trial name
- NCT03642470
- Where
- Switzerland
- Volunteers
- 197 people
- Sponsor
- University Children's Hospital, Zurich
Cardiovascular Risk Factor, Hypercholesterolemia
The Effect of Viscous Dietary Fibers on LDL-cholesterol
This systematic review and meta-analysis is aimed to assess the effect of commonly consumed viscous fibers on blood lipids including LDL-C, non-HDL-C, and ApoB.
- Trial name
- NCT04133805
- Testing
- viscous fiber
- Where
- Canada
- Volunteers
- 7,845 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Cerebrotendinous Xanthomatosis (CTX)
Evaluation of Carotid IMT and Atherogenic Risk Factors in Patients With Cerebrotendinous Xanthomatosis
The aim of the proposed study is to evaluate the risk for cardiovascular disease and 'atherogenic' features of the serum in CTX and to determine preclinical atherosclerosis.
- Trial name
- CTX (NCT01613898)
- Testing
- Blood tests
- Where
- Israel
- Volunteers
- 17 people
- Sponsor
- Sheba Medical Center
Diabetes Mellitus, Type 2
Effect of Repaglinide Versus Metformin Treatment in Non-Obese Patients With Type-2-Diabetes
Aim: The United Kingdom Prospective Diabetes Study (UKPDS) showed a reduction in cardiovascular events in obese patients with type-2-diabetes treated with metformin compared with other hypoglycaemic treatments with no difference…
- Trial name
- NCT00118963
- Testing
- Metformin, Insulin BIAsp30 (Novolog 70/30), Repaglinide
- Where
- Denmark
- Volunteers
- 102 people
- Sponsor
- Steno Diabetes Center Copenhagen
Dyslipidemias, Atherosclerosis
Dyslipidemia Prevalence, Perception, Treatment, and Awareness in the Tunisian Population
ATERA Survey is a national cross sectional observational study, aiming to determine the prevalence of dyslipidemia and other conventional risk factors for CHD (Coronary Heart Disease), the relationship between environmental and…
- Conditions
- Dyslipidemias, Atherosclerosis, Households, Survey, Family Life
- Trial name
- ATERASurvey (NCT03799185)
- Where
- Tunisia
- Volunteers
- 13,610 people, healthy volunteers welcome
- Sponsor
- Association Tunisienne d'Etude & de Recherche sur l'Athérosclérose
Type II Diabetes Mellitus, Intermediate Hyperglycemia (IHG)
Engagement of coMmunity Through Participatory Learning and Action for cOntrol and preVEntion of Type II Diabetes and Its Risk Factors [EMPOWER-D]
This project aims to adapt, implement, and evaluate Participatory Learning and Action (PLA) based intervention in rural areas of KPK, Pakistan which includes Peshawar and Swabi for TIIDM prevention and control.
- Trial name
- NCT06561126
- Testing
- Participatory, Learning and Action Based Intervention
- Where
- Pakistan
- Volunteers
- 12,744 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Cardiovascular Diseases, Diabetes Mellitus, Type 2
Exercise Training in Older Diabetic Women
Type 2 diabetics (non-insulin-dependent) are more than five times as likely to suffer an initial myocardial infarction (MI; heart attack) compared to nondiabetics.Female diabetics in particular, have a higher mortality rate for…
- Trial name
- NCT00341614
- Testing
- 3-month Exercise Training and Diet Education
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of San Francisco
Diabetes, Dyslipidemia
Strategies to Maintain Cardiac Risk Control After Discharge From Cardiovascular Risk Reduction Clinic
The purpose of this study is to determine whether a combined behavioral and pharmacological intervention provided by a multidisciplinary team will further reduce LDL-C, smoking, BP and Hb-A1C in diabetic patients with A1c between…
- Conditions
- Diabetes, Dyslipidemia, Hypertension, Coronary Atherosclerosis
- Trial name
- NCT00358033
- Testing
- Counseling, Interactive Education, Group Support
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Providence VA Medical Center
Microbiome, Metabolic Syndrome
Dietary Fibers Effect on the Gut Microbiota Composition
The randomized double-blinded placebo-controlled multicenter study will be held in parallel groups. During 5 weeks the efficacy of different endpoints as a measure of response to the daily intake of dietary fibers (8 g of either…
- Conditions
- Microbiome, Metabolic Syndrome, Cardiovascular Risk Factor, Inflammation
- Trial name
- NCT04114513
- Testing
- Maltodextrin, Inulin, Pectin
- Where
- Russia
- Volunteers
- healthy volunteers welcome
- Sponsor
- Atlas Biomed
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