Clinical trials: Metabolic Surgery
Postoperative Nausea and Vomiting, Postoperative Pain
Effect of Ultrasound-guided Transversus Abdominis Plane Block After Laparoscopic Bariatric Surgery
To explore and compare Ultrasound-Guided Transversus Abdominis Plane Block on Postoperative nausea and vomiting and Early Outcome After Laparoscopic Bariatric Surgery To evaluate and examine TAPB can reduce the application of…
- Trial name
- NCT05286008
- Testing
- Normal saline, Ropivacaine at high concentration, Ropivacaine and dexamethasone
- Volunteers
- 90 people
- Sponsor
- Tianjin Medical University General Hospital
Osteoarthritis, Knee, Prosthesis User
Characteristics of Marrow Fatty Cells in the Ageing of Bone and Joints, Osteoarthritis and Osteoporosis
Obesity and other associated complications promote the development and the progression of osteoarthritis. The subcutaneous and abdominal fat release several factors that alter bone and the cartilage.
- Trial name
- MEDADIPO (NCT03678831)
- Testing
- tissue
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Lille
Obesity, Bariatric Surgery
Opioid-Free Versus Opioid-Based Anesthesia in Bariatric
This study is designed as a prospective, randomized, controlled clinical trial. It will be conducted in the operating rooms of the University of Health Sciences, Diyarbakır Gazi Yaşargil Training and Research Hospital.
- Trial name
- NCT07105839
- Testing
- Intraoperative rescue analgesia, Intraoperative rescue analgesia:
- Volunteers
- 50 people
- Sponsor
- Siirt Training and Research Hospital
Hypoglycemia, Perioperative Complication
Wireless Assessment of Respiratory and Circulatory Distress - Continuous Glucose Monitoring
The applicant and research team partners have over the last years developed the WARD project (Wireless Assessment of Respiratory and circulatory Distress), using wireless continuous monitoring of vital signs in high-risk patients…
- Trial name
- WARD-CGM (NCT04473001)
- Testing
- Continuous vital signs and glucose monitoring
- Where
- 2 sites in Denmark
- Volunteers
- 70 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Postoperative Pain, Bariatric Surgery Candidate
Intravenous Ibuprofen Versus Ketorolac in Bariatric Surgery
The aim of the current study is to compare the analgesic effects of both drugs in patients with obesity undergoing bariatric surgery.
- Trial name
- NCT05801900
- Testing
- Ketorolac group, Ibuprofen group
- Where
- Egypt
- Volunteers
- 116 people
- Sponsor
- Cairo University
Obesity
Prebariatric Surgery Physical Activity Program
Introduction: According to studies, a low physical capacity before surgery is linked with smaller weigh loss after surgery and increases risks of peri-surgical complications.
- Trial name
- NCT01452230
- Testing
- Supervised physical activity
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- Université de Sherbrooke
Bariatric Surgery, Morbid Obesity
Pharmacokinetics of Rivaroxaban After Bariatric Surgery
Data on pharmacokinetics of rivaroxaban after bariatric surgery and in morbid obesity are sparse. The aim of this study is to assess the pharmacokinetic and pharmacodynamic parameters of rivaroxaban, used at a therapeutic…
- Trial name
- ABSORB (NCT04180436)
- Testing
- rivaroxaban 20 mg once daily 8 days
- Where
- France
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Obesity, Severe, Surgery
Connected Scales to Optimize the Maintenance of Weight Lost After Bariatric Surgery and Limit Failures and Reoperations
In this research, we hypothesize that post-operative monitoring implemented with a connected scale after the 1st year (weight nadir period) post obesity surgery (i.e.
- Trial name
- COMPA (NCT06133413)
- Testing
- Body Comp Pro connected scale (Withings manufacturer), Alert generation by remote plateform
- Where
- France
- Volunteers
- 182 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Postoperative Pain, Obesity
Comparison of Two Magnesium Sulfate Protocols in Opioid-Free Anesthesia for Bariatric Surgery
This retrospective observational study aims to compare postoperative morphine consumption in patients undergoing bariatric surgery with opioid-free anesthesia (OFA) using two different intravenous magnesium sulfate administration…
- Conditions
- Postoperative Pain, Obesity, Bariatric Surgery, Opioid-free Anesthesia
- Trial name
- OFA-MG (NCT07077031)
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Hospital HM Nou Delfos
Metabolic Associated Fatty Liver Disease, Bariatric Surgery Candidate
Short Term Outcome of Metabolic Associated Fatty Liver Disease (MAFLD) in Patients Undergoing Bariatric Surgery
Obesity has become one of the most critical public health problems in economically developed and developing countries in the world.
- Trial name
- NCT06180928
- Volunteers
- 50 people
- Sponsor
- Assiut University
Diabetes, Surgery
Perioperative Insulin Glargine Dosing Study
The main objective of this study is to compare three strategies of evening insulin glargine dosing to preoperative glucose values in patients with diabetes undergoing surgery to determine which dosing strategies most often…
- Trial name
- NCT00309465
- Testing
- Lantus, Insulin
- Where
- 2 sites in United States
- Volunteers
- 402 people
- Sponsor
- Tamra Dukatz
Bariatric Surgery Candidate
Effects of Technology-based Physical Activity Interventions for Women After Bariatric Surgery
Regular physical activity (PA) is essential throughout bariatric surgery (BS) management, especially for the long-term maintenance of weight loss.
- Trial name
- OCAPAS (NCT04478331)
- Testing
- Technology-based physical activity interventions
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Pr Fabienne d'Arripe-Longueville
Bariatric Surgery Candidate, Heart Failure
CV Imaging of Metabolic Interventions
Cardiovascular disease is the leading cause of death worldwide. It is becoming clearer that heart failure (HF) is closely associated with body's metabolism.
- Conditions
- Bariatric Surgery Candidate, Heart Failure, Cardiovascular Diseases
- Trial name
- CIRCMeta (NCT05650307)
- Testing
- MRI
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Bariatric Surgery in Postmenopausal Women
Bone Marrow Fat and Bariatric Surgery-Mediated Bone Loss
Results are inconsistent and further studies are needed to better understand the impact of bariatric surgery on the bone-BMA relationship depending on the type of bariatric surgery: RYGB vs. SG.
- Trial name
- ADIMOS-OB (NCT05005039)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Lille
Cardiac Surgery
Epicardial Fat Immunity extRa Cellular vesicleS HearT
The FIRST study is a monocentric observational pilot study investigating the role of extracellular vesicles (EVs) derived from epicardial adipose tissue (EAT) in cardiovascular complications associated with obesity.
- Trial name
- FIRST (NCT07817667)
- Testing
- Epicardial adipose tissue biopsy, Thoracic subcutaneous adipose tissue biopsy
- Volunteers
- 100 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Insulin Resistance, Cardiac Surgery Requiring Cardiopulmonary Bypass
Relation Between Insulinoresistance and Neutrophile to Lymphocyte Ratio in Cardiac Surgery.
The University Hospital of Besançon is conducting a public interest research project called CRYSTAL, who studies the relationship between the Neutrophil to Lymphocyte ratio (NLR) and insulin resistance in post-operative cardiac…
- Conditions
- Insulin Resistance, Cardiac Surgery Requiring Cardiopulmonary Bypass, Neutrophil Lymphocyte Ratio
- Trial name
- CRYSTAL (NCT06945536)
- Where
- France
- Volunteers
- 211 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Type2 Diabetes, Weight Loss
Improving Glucose and Lipid Metabolism Through Caloric Restriction Using Diet or Surgery (CRUDOS)
In this explorative randomized clinical study, the investigators aim to study metabolic, cellular, and molecular changes that occur during weight loss in obese subjects with and without type 2 diabetes.
- Conditions
- Type2 Diabetes, Weight Loss, Insulin Sensitivity, Metabolism and Nutrition Disorder
- Trial name
- CRUDOS (NCT02988011)
- Testing
- Gastric by-pass surgery, Low-caloric diet
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Uppsala University
Neoplasms, Aged
Silent Threat: Impact of Preoperative Albumin Levels on Outcomes in Geriatric Cancer Surgery
This retrospective, single-center study aims to evaluate the impact of preoperative albumin levels on postoperative outcomes in geriatric patients (aged 65 and above) undergoing cancer surgery.
- Conditions
- Neoplasms, Aged, Hypoalbuminemia, Postoperative Complications
- Trial name
- NCT06998030
- Where
- Turkey (Türkiye)
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Osteoporosis
Role of T-cells in Post-Menopausal Osteoporosis
This is an observational study of women undergoing surgical menopause to determine whether T-cells play an important role in the etiology of post-menopausal osteoporosis.
- Trial name
- NCT00787904
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Atlanta VA Medical Center
Obesity
Rapid Eating Is Linked to Emotional Eating in Obese Women Relieving From Bariatric Surgery
The aim of the study was to analyse eating rate in comparison to other aspects of eating habits in women suffering from severe/massive obesity.
- Trial name
- BS-Women (NCT03949595)
- Testing
- Data collection
- Where
- France
- Volunteers
- 116 people
- Sponsor
- CHU de Reims