Clinical trials: Metabolic Syndrome
Celiac Disease
Oral AGY for Celiac Disease
Celiac disease (CD) is an autoimmune disease of the small intestine caused by the consumption of gluten proteins from widely used food sources such as wheat, rye, and barley.
- Trial name
- NCT01765647
- Testing
- AGY
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Igy Inc.
Metabolic Syndrome, Insulin Resistance
The Effects of the Telomerase Activator TA-65 on Insulin Resistance, Inflammation, and Metabolic Syndrome
Our hypothesis is that TA-65, a dietary supplement will help to reduce insulin resistance and plasma glucose in individuals classified with metabolic syndrome.
- Trial name
- NCT01753674
- Testing
- TA-65
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Metabolic Syndrome, Bipolar Depression
Pioglitazone for the Treatment of Bipolar Disorder and Comorbid Metabolic Syndrome or Insulin Resistance
The study is an open-label 8-week adjunctive trial of pioglitazone for the acute relief of bipolar depression comorbid with metabolic syndrome/insulin resistance.
- Conditions
- Metabolic Syndrome, Bipolar Depression, Insulin Resistance
- Trial name
- NCT00835120
- Testing
- Pioglitazone
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University Hospitals Cleveland Medical Center
Growth Disorders, Metabolic Syndrome
The Effect of Milk and Meat on IGFs in Prepubertal Boys
The objective of the study is to examine whether a 7-day high protein intake from either milk or meat in healthy, prepubertal children can increase fasting levels of serum IGF-I, IGFBP-3 and IGF-I/IGFBP-3 as well as insulin…
- Trial name
- NCT00378859
- Testing
- Skim milk, Lean meat
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
MPS IIIA, Sanfilippo Syndrome
Phase I/II/III Gene Transfer Clinical Trial of scAAV9.U1a.hSGSH
The main objective of this study is to evaluate the efficacy and safety of UX111 for the treatment of MPS IIIA.
- Conditions
- MPS IIIA, Sanfilippo Syndrome, Sanfilippo A, Mucopolysaccharidosis III
- Trial name
- NCT02716246
- Testing
- UX111, Prophylactic Immunomodulatory (IM) Therapy, Optimized Prophylactic IM Therapy
- Where
- 5 sites in United States, Australia and 1 more
- Volunteers
- 36 people
- Sponsor
- Ultragenyx Pharmaceutical Inc
Morquio's Disease
Morquio's Syndrome: a Case Study
OBJECTIVES: Relating about the benefits proportionated by the physiotherapeutic treatment for the patients that have the Morquio's syndrome.
- Trial name
- NCT00609440
- Testing
- physiotherapeutic treatment
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Clínica de Hidroterapia e Recuperacao Funcional
Obesity, Diabetes
Ketogenic Diet Treatment of Obesity With Co-morbid Type 2 Diabetes Mellitus and/or Obstructive Sleep Apnea
The purpose of the study is to evaluate the efficacy and safety of ketogenic diet (KD) treatment of (i) obesity, (ii) type 2 diabetes mellitus and (iii) obstructive sleep apnea (OSA) in patients with obesity and Type 2 DM and in…
- Conditions
- Obesity, Diabetes, Obstructive Sleep Apnea
- Trial name
- KGDobesity (NCT02069197)
- Testing
- Ketogenic diet, Orlistat, Standardized diet
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Mid-Atlantic Epilepsy and Sleep Center, LLC
Down Syndrome, Vitamin D Deficiency
Effect of Exercise Intensity on Vitamin D
Children with Down's syndrome (DS) are more liable to vitamin D deficiency. Treating this deficiency with supplements is associated with the risk of intoxication due to increased intestinal absorption or decreased vitamin D…
- Trial name
- NCT05024110
- Testing
- High intensity treamill exercise training., Moderate intensity treamill exercise training.
- Where
- Saudi Arabia
- Volunteers
- 44 people
- Sponsor
- Taif University
MPS IIIB (Sanfilippo B Syndrome)
Evaluation of Blood Brain Barrier Integrity and Structural Abnormalities in MPS IIIB Patients Using Multimodal Magnetic Resonance Imaging
The purpose of the study is to characterize structural abnormalities in the brain and the integrity of the blood brain barrier in patients with mucopolysaccharidosis type IIIB (MPS IIIB).
- Trial name
- NCT02090179
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Prader Willi Syndrome, Obesity
Correlation of Hyperghrelinemia With Carotid Artery Intima-Media Thickness in Children With Prader-Willi Syndrome
Prader-Willi syndrome (PWS) is a genetic disorder characterized by childhood-onset obesity and endocrine dysfunction that leads to cardiovascular disability and early death within the first 3 decades of life.To assess the…
- Trial name
- NCT00474643
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Lynch Syndrome
Naproxen in Preventing DNA Mismatch Repair Deficient Colorectal Cancer in Patients With Lynch Syndrome
This randomized phase Ib trial studies the side effects and best dose of naproxen in preventing deoxyribonucleic acid (DNA) mismatch repair deficient colorectal cancer in patients with Lynch syndrome.
- Trial name
- NCT02052908
- Testing
- Laboratory Biomarker Analysis, Naproxen
- Where
- 4 sites in United States
- Volunteers
- 81 people
- Sponsor
- National Cancer Institute (NCI)
Metabolic Syndrome
Effects of Functional Ingredients in an Acute Metabolic Challenge Context
After an energy-rich meal the blood levels of glucose and lipids undergo a marked temporary increase, triggering a wave of oxidative stress due to the appearance of excess free radicals in adipose and muscle tissues.
- Trial name
- NCT02623608
- Testing
- Reference breakfast, Active Ingredient 1, Active Ingredient 2
- Where
- Sweden
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Lund University
Prostate Cancer, Breast Cancer
Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis
Background: Some genes may be associated with a greater chance of side effects during cancer treatment. These genes may also make certain treatments less effective.
- Conditions
- Prostate Cancer, Breast Cancer, Lung Cancer, Ovarian Cancer
- Trial name
- NCT01441089
- Where
- United States
- Volunteers
- 1,100 people
- Sponsor
- National Cancer Institute (NCI)
Obstructive Sleep Apnea (OSA), Bariatric Surgery
Desaturations and Nursing Interventions in Patients Receiving Supplemental Oxygen Therapy After Metabolic and Bariatric Surgery
The goal of this observational study is to learn about the effect of supplemental oxygen therapy during the first night after bariatric and metabolic surgery in a population that is not (routinely) tested for obstructive sleep…
- Trial name
- SATBAR (NCT07174674)
- Where
- Netherlands
- Volunteers
- 563 people
- Sponsor
- Rijnstate Hospital
Metabolic Syndrome
Korean Red Ginseng and Metabolic Syndrome
Five factor consisting of Metabolic syndrome is closely linked by insulin resistance. Until now, several studies have been performed about effects of Korea red ginseng on hypertension, diabetes, and hyperlipidemia, but not…
- Trial name
- NCT00976274
- Testing
- Korean red ginseng, starch
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- The Korean Society of Ginseng
Refeeding Syndrome, Acute Abdomen
Refeeding Like Syndrome in Acute Disease
The refeeding syndrome has been reported without any evidence of prolopnged semistarvation, thus being different from the traditional disease.
- Trial name
- RLS (NCT04966780)
- Testing
- acute abdominal surgery
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Jens Rikardt Andersen
Restless Legs
Intravenous Iron Metabolism in Restless Legs Syndrome
Double-blind, placebo-controlled, entitled: "Intravenous Iron Metabolism in Restless Legs Syndrome
- Trial name
- RLS (NCT00685815)
- Testing
- Ferric Carboxymaltose (FCM)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- American Regent, Inc.
Metabolic Syndrome, Overweight and Obesity
Effects of Early and Late Time-restricted Eating on Overweight Adults With Metabolic Syndrome
Investigators aim to compare the effects of early and late time-restricted feeding on overweight adults with metabolic syndrome
- Conditions
- Metabolic Syndrome, Overweight and Obesity, Time Restricted Eating
- Trial name
- NCT06018415
- Testing
- Early time-restricted eating (eTRE), Late time-restricted eating (lTRE)
- Where
- China
- Volunteers
- 103 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Metabolic Syndrome
The Effect of Supplementation of Flaxseed, Hesperidin, Flaxseed and Hesperidin Together in Metabolic Syndrome
To study the effects of Hesperidin, flaxseed and both together in patients with metabolic syndrome, 100 patients will be randomly allocated to one of following four groups: control group, hesperidin group (2 capsules Hesperidin)…
- Trial name
- NCT03734835
- Testing
- hesperidin, hesperidin and flaxseed, flaxseed
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- National Nutrition and Food Technology Institute
Hypertension, Metabolic Syndrome
WB-EMS Effects on Cardiometabolic Risk Factors
From the age of 50 onwards, there is a disproportionate decline in muscle strength, mass and function, which can be prevented or at least delayed by physical training.
- Conditions
- Hypertension, Metabolic Syndrome, Hypercholesterolemia, Hypertriglyceridemia
- Trial name
- NCT07406191
- Testing
- WB-EMS, Control
- Where
- 2 sites in Germany
- Volunteers
- 28 people
- Sponsor
- University of Erlangen-Nürnberg Medical School